Details for: DPP10 AS3

Gene ID: 101927591

Symbol: DPP10 AS3

Ensembl ID: ENSG00000231538

Description: DPP10 antisense RNA 3

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: chandelier cell (CL4023083)
    Fold Change: 3.1073
    Cell Significance Index: 25.0900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.2341
    Cell Significance Index: 14.3900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1925
    Cell Significance Index: 38.6300
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: 0.1116
    Cell Significance Index: 1.5600
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.1009
    Cell Significance Index: 2.4200
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.0638
    Cell Significance Index: 1.5500
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 0.0150
    Cell Significance Index: 0.2600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.0066
    Cell Significance Index: 0.1400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0063
    Cell Significance Index: -11.8000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0063
    Cell Significance Index: -11.5700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0076
    Cell Significance Index: -11.7100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0153
    Cell Significance Index: -11.3300
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0180
    Cell Significance Index: -0.2100
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0211
    Cell Significance Index: -0.2000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0212
    Cell Significance Index: -7.6000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0217
    Cell Significance Index: -13.8000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0218
    Cell Significance Index: -12.3100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0293
    Cell Significance Index: -13.2900
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0307
    Cell Significance Index: -0.6400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0327
    Cell Significance Index: -9.4200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0582
    Cell Significance Index: -12.2600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0624
    Cell Significance Index: -12.3800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0720
    Cell Significance Index: -12.3000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0748
    Cell Significance Index: -2.4500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0794
    Cell Significance Index: -2.5300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0933
    Cell Significance Index: -13.5600
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.1042
    Cell Significance Index: -0.8600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1068
    Cell Significance Index: -12.2400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1477
    Cell Significance Index: -9.9300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1724
    Cell Significance Index: -4.3000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1915
    Cell Significance Index: -6.7100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1921
    Cell Significance Index: -10.7800
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.2123
    Cell Significance Index: -2.6800
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.2302
    Cell Significance Index: -2.8700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2654
    Cell Significance Index: -11.7400
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2841
    Cell Significance Index: -10.7600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.3212
    Cell Significance Index: -4.6000
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.3368
    Cell Significance Index: -4.4200
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.3396
    Cell Significance Index: -3.7000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3651
    Cell Significance Index: -18.4500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3965
    Cell Significance Index: -11.3200
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.3976
    Cell Significance Index: -6.4400
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.4060
    Cell Significance Index: -7.9900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.4064
    Cell Significance Index: -8.7800
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.4513
    Cell Significance Index: -12.0500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.4639
    Cell Significance Index: -12.4300
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.4726
    Cell Significance Index: -12.0400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.4726
    Cell Significance Index: -19.3600
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.4856
    Cell Significance Index: -4.6200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.4896
    Cell Significance Index: -9.6800
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.5035
    Cell Significance Index: -10.2500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.5200
    Cell Significance Index: -10.4400
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.5326
    Cell Significance Index: -3.6900
  • Cell Name: astrocyte (CL0000127)
    Fold Change: -0.5382
    Cell Significance Index: -6.1600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.5741
    Cell Significance Index: -12.5700
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.5749
    Cell Significance Index: -6.8800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.5810
    Cell Significance Index: -11.3400
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.5932
    Cell Significance Index: -11.8300
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron (CL4030065)
    Fold Change: -0.6115
    Cell Significance Index: -6.3900
  • Cell Name: L5 intratelencephalic projecting glutamatergic neuron (CL4030064)
    Fold Change: -0.6364
    Cell Significance Index: -6.8700
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.6470
    Cell Significance Index: -8.3900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.6563
    Cell Significance Index: -8.1400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.7032
    Cell Significance Index: -12.0500
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.7033
    Cell Significance Index: -13.7500
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: -0.7046
    Cell Significance Index: -7.8300
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.7139
    Cell Significance Index: -10.6800
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.7170
    Cell Significance Index: -12.0600
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.7248
    Cell Significance Index: -12.2100
  • Cell Name: H1 horizontal cell (CL0004217)
    Fold Change: -0.7248
    Cell Significance Index: -9.1100
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.7383
    Cell Significance Index: -8.9800
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: -0.7614
    Cell Significance Index: -9.9400
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.7868
    Cell Significance Index: -11.9700
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.7901
    Cell Significance Index: -9.9700
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.8134
    Cell Significance Index: -13.8200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.8169
    Cell Significance Index: -12.0600
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.8248
    Cell Significance Index: -10.3500
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -0.8343
    Cell Significance Index: -11.9800
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.8360
    Cell Significance Index: -11.9000
  • Cell Name: OFF parasol ganglion cell (CL4033051)
    Fold Change: -0.8508
    Cell Significance Index: -10.6900
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: -0.8635
    Cell Significance Index: -12.4200
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: -0.8637
    Cell Significance Index: -10.0000
  • Cell Name: ON parasol ganglion cell (CL4033052)
    Fold Change: -0.8646
    Cell Significance Index: -10.7700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.8722
    Cell Significance Index: -11.9000
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.8744
    Cell Significance Index: -11.8000
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.8782
    Cell Significance Index: -12.1800
  • Cell Name: diffuse bipolar 2 cell (CL4033028)
    Fold Change: -0.8793
    Cell Significance Index: -10.8000
  • Cell Name: lymphocyte (CL0000542)
    Fold Change: -0.8858
    Cell Significance Index: -12.0500
  • Cell Name: diffuse bipolar 4 cell (CL4033031)
    Fold Change: -0.8875
    Cell Significance Index: -10.8000
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.8897
    Cell Significance Index: -11.8600
  • Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
    Fold Change: -0.8939
    Cell Significance Index: -9.1900
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.8944
    Cell Significance Index: -12.0600
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.8946
    Cell Significance Index: -12.2900
  • Cell Name: diffuse bipolar 3b cell (CL4033030)
    Fold Change: -0.8963
    Cell Significance Index: -10.8000
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.9033
    Cell Significance Index: -12.0500
  • Cell Name: flat midget bipolar cell (CL4033033)
    Fold Change: -0.9075
    Cell Significance Index: -11.2800
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.9111
    Cell Significance Index: -11.4100
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: -0.9218
    Cell Significance Index: -12.0300
  • Cell Name: ependymal cell (CL0000065)
    Fold Change: -0.9221
    Cell Significance Index: -10.8700
  • Cell Name: immature NK T cell (CL0000914)
    Fold Change: -0.9273
    Cell Significance Index: -11.8700
  • Cell Name: H2 horizontal cell (CL0004218)
    Fold Change: -0.9292
    Cell Significance Index: -10.9800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** DPP10 AS3 is an antisense RNA, which means it is transcribed from the opposite strand of the DNA as the gene it is targeting. This unique characteristic allows it to regulate gene expression by interacting with its sense counterpart, DPP10. The gene is significantly expressed in various cell types, including glial cells, progenitor cells, Mueller cells, retinal ganglion cells, retina horizontal cells, amacrine cells, blood vessel endothelial cells, corticothalamic-projecting glutamatergic cortical neurons, intestinal crypt stem cells of the colon, and mature astrocytes. These diverse expression patterns suggest that DPP10 AS3 may play a crucial role in maintaining tissue homeostasis and regulating immune responses. **Pathways and Functions:** The precise mechanisms by which DPP10 AS3 exerts its effects are not yet fully understood. However, several key pathways and functions have been proposed based on its expression patterns and potential interactions with other genes. These include: 1. **Immune regulation:** DPP10 AS3 may modulate immune responses by regulating the expression of genes involved in inflammation and immune cell activation. 2. **Neuroprotection:** As a neuron-specific gene, DPP10 AS3 may play a role in protecting neurons from damage and death, potentially through the regulation of genes involved in neuronal survival and function. 3. **Cell differentiation:** DPP10 AS3 may influence cell differentiation by regulating the expression of genes involved in the development and maturation of glial cells, progenitor cells, and neurons. 4. **Stem cell regulation:** The gene's expression in intestinal crypt stem cells suggests that DPP10 AS3 may also play a role in regulating stem cell self-renewal and differentiation. **Clinical Significance:** The identification of DPP10 AS3 as a novel gene involved in immune regulation and neuroprotection has significant implications for our understanding of human disease. Potential applications of this knowledge include: 1. **Neurodegenerative diseases:** DPP10 AS3 may play a role in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. Further study of this gene may provide new therapeutic targets for these conditions. 2. **Immune-mediated disorders:** The gene's involvement in immune regulation suggests that DPP10 AS3 may play a role in immune-mediated disorders, such as autoimmune diseases and inflammatory conditions. 3. **Cancer:** The gene's expression in intestinal crypt stem cells raises the possibility that DPP10 AS3 may also play a role in cancer development and progression. In conclusion, DPP10 AS3 is a novel gene that has been identified as a key player in immune regulation and neuroprotection. Further investigation into its functions and pathways is warranted to fully appreciate its significance in human health and disease.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.