Details for: DDC

Gene ID: 1644

Symbol: DDC

Ensembl ID: ENSG00000132437

Description: dopa decarboxylase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 18.5694
    Cell Significance Index: -4.7100
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 17.6479
    Cell Significance Index: -7.2700
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 12.2293
    Cell Significance Index: 92.7400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 9.9226
    Cell Significance Index: 625.3900
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 8.4647
    Cell Significance Index: -5.6800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 4.7550
    Cell Significance Index: 328.8400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 3.1622
    Cell Significance Index: 91.1100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 2.9285
    Cell Significance Index: -7.8500
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: 2.6544
    Cell Significance Index: 20.4600
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 2.3253
    Cell Significance Index: 39.1100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.7426
    Cell Significance Index: 1573.4700
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 1.5920
    Cell Significance Index: 16.0600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.5292
    Cell Significance Index: 33.1300
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 1.4937
    Cell Significance Index: 22.5100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.4918
    Cell Significance Index: 31.7700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.1973
    Cell Significance Index: 194.7400
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 1.0909
    Cell Significance Index: 8.7100
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0845
    Cell Significance Index: 107.2800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.0026
    Cell Significance Index: 60.1900
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 0.8367
    Cell Significance Index: 7.3700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6933
    Cell Significance Index: 131.9300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.6843
    Cell Significance Index: 31.0200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.6843
    Cell Significance Index: 74.4300
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 0.6739
    Cell Significance Index: 7.4300
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.5177
    Cell Significance Index: 16.5800
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 0.4591
    Cell Significance Index: 4.0500
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.3489
    Cell Significance Index: 5.7500
  • Cell Name: colonocyte (CL1000347)
    Fold Change: 0.3301
    Cell Significance Index: 2.0400
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.2470
    Cell Significance Index: 2.0000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.2037
    Cell Significance Index: 6.0000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1956
    Cell Significance Index: 38.8200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1853
    Cell Significance Index: 6.5100
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 0.1782
    Cell Significance Index: 2.1600
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 0.1563
    Cell Significance Index: 1.1000
  • Cell Name: stem cell (CL0000034)
    Fold Change: 0.1541
    Cell Significance Index: 1.1200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0889
    Cell Significance Index: 1.0600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: 0.0576
    Cell Significance Index: 4.5600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0401
    Cell Significance Index: 4.6700
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.0279
    Cell Significance Index: 0.2300
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 0.0260
    Cell Significance Index: 0.2000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0236
    Cell Significance Index: 4.0300
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: 0.0175
    Cell Significance Index: 0.0900
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: 0.0163
    Cell Significance Index: 0.1800
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 0.0113
    Cell Significance Index: 0.0700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0049
    Cell Significance Index: 3.3900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0043
    Cell Significance Index: 2.6800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.0019
    Cell Significance Index: 1.4300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0008
    Cell Significance Index: 0.0200
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0007
    Cell Significance Index: -0.4000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0021
    Cell Significance Index: -4.0300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0022
    Cell Significance Index: -4.1000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0027
    Cell Significance Index: -2.0100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0028
    Cell Significance Index: -4.3800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0034
    Cell Significance Index: -4.6700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0039
    Cell Significance Index: -0.7900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0049
    Cell Significance Index: -0.0700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0050
    Cell Significance Index: -3.6900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0068
    Cell Significance Index: -1.4400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0071
    Cell Significance Index: -0.8100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0080
    Cell Significance Index: -4.3500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0083
    Cell Significance Index: -0.3400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0108
    Cell Significance Index: -6.8800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0113
    Cell Significance Index: -3.2600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0118
    Cell Significance Index: -4.2300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0126
    Cell Significance Index: -5.7300
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0138
    Cell Significance Index: -1.5700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0145
    Cell Significance Index: -0.4100
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.0151
    Cell Significance Index: -0.1900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0168
    Cell Significance Index: -0.4500
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0187
    Cell Significance Index: -0.9400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0207
    Cell Significance Index: -2.1100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0302
    Cell Significance Index: -1.8500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0305
    Cell Significance Index: -5.5000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0339
    Cell Significance Index: -4.6500
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.0398
    Cell Significance Index: -0.4500
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.0425
    Cell Significance Index: -0.3700
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0430
    Cell Significance Index: -0.4500
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0432
    Cell Significance Index: -1.0800
  • Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
    Fold Change: -0.0451
    Cell Significance Index: -0.3800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0454
    Cell Significance Index: -6.6000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0461
    Cell Significance Index: -5.6700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0465
    Cell Significance Index: -4.8500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.0469
    Cell Significance Index: -0.3200
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0541
    Cell Significance Index: -1.3500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0547
    Cell Significance Index: -1.4900
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.0553
    Cell Significance Index: -0.4700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0565
    Cell Significance Index: -0.6400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0689
    Cell Significance Index: -8.1300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0706
    Cell Significance Index: -4.7500
  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: -0.0726
    Cell Significance Index: -0.9200
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0815
    Cell Significance Index: -0.8600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0869
    Cell Significance Index: -1.8200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0893
    Cell Significance Index: -5.0100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0916
    Cell Significance Index: -4.8100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1010
    Cell Significance Index: -5.2500
  • Cell Name: goblet cell (CL0000160)
    Fold Change: -0.1017
    Cell Significance Index: -0.9200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1036
    Cell Significance Index: -1.7800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1060
    Cell Significance Index: -4.6900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1060
    Cell Significance Index: -4.9400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** DDC is a pyridoxal phosphate-dependent enzyme, meaning it requires the coenzyme pyridoxal phosphate to catalyze its reaction. This enzyme is also a member of the aromatic L-amino-acid decarboxylase family, which includes other enzymes involved in the decarboxylation of aromatic amino acids. DDC has a high degree of specificity for L-tryptophan, with a Km value of approximately 10-20 μM, indicating its high affinity for this substrate. The enzyme is also sensitive to inhibition by various compounds, including the neurotoxin 6-OHDA, which is commonly used in research to study the effects of dopamine depletion. **Pathways and Functions** DDC is involved in several key metabolic pathways, including: 1. **Catecholamine biosynthesis**: DDC catalyzes the conversion of L-tryptophan to dopamine, which is then further converted to norepinephrine and epinephrine through a series of reactions involving other enzymes. 2. **Amino acid metabolism**: DDC plays a role in the degradation of aromatic amino acids, including tryptophan and tyrosine. 3. **Neurotransmitter regulation**: DDC is involved in regulating the levels of dopamine, norepinephrine, and epinephrine in the brain and peripheral tissues. 4. **Response to toxic substances**: DDC is sensitive to inhibition by various toxins, including 6-OHDA, and plays a role in responding to these substances in the body. **Clinical Significance** DDC has significant clinical implications, particularly in the context of neurodegenerative disorders. For example: 1. **Parkinson's disease**: DDC is involved in the production of dopamine, which is depleted in Parkinson's disease. Inhibitors of DDC, such as carbidopa, are often used in combination with levodopa to treat this condition. 2. **Neurotoxicity**: DDC is sensitive to inhibition by various toxins, including 6-OHDA, which can be used to study the effects of dopamine depletion in research. 3. **Cancer**: DDC has been implicated in the development and progression of certain types of cancer, including neuroblastoma and melanoma. 4. **Neurodevelopmental disorders**: DDC plays a role in the regulation of neurotransmitter levels in the developing brain, and abnormalities in DDC expression have been implicated in neurodevelopmental disorders, such as autism and schizophrenia. In conclusion, Dopa decarboxylase is a critical enzyme involved in the biosynthesis of catecholamines and has significant implications for our understanding of neurodegenerative disorders, cancer, and neurodevelopmental disorders. Further research is needed to fully elucidate the functions and clinical significance of this enzyme.

Genular Protein ID: 4071522668

Symbol: DDC_HUMAN

Name: N/A

UniProtKB Accession Codes:

P20711 C9IYA0 E7ER62 E7EU95 Q16723 Q5W5T9 Q75MJ6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CTD 1 ChEBI 13 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 11 DrugCentral 1 EC 3 EMBL 22 Ensembl 6 EvolutionaryTrace 1 ExpressionAtlas 1 GO 16 Gene3D 3 GeneCards 1 GeneReviews 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 5 PDBsum 5 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 2 RefSeq 7 Rhea 2 SABIO-RK 1 SASBDB 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2590185

Title: Isolation and characterization of a cDNA clone encoding human aromatic L-amino acid decarboxylase.

PubMed ID: 2590185

DOI: 10.1016/0006-291x(89)91772-5

PubMed ID: 1612608

Title: Human dopa decarboxylase: localization to human chromosome 7p11 and characterization of hepatic cDNAs.

PubMed ID: 1612608

DOI: 10.1016/0888-7543(92)90275-w

PubMed ID: 1540578

Title: Molecular cloning of genomic DNA and chromosomal assignment of the gene for human aromatic L-amino acid decarboxylase, the enzyme for catecholamine and serotonin biosynthesis.

PubMed ID: 1540578

DOI: 10.1021/bi00123a004

PubMed ID: 15532536

Title: Identification and characterization of a novel form of the human L-dopa decarboxylase mRNA.

PubMed ID: 15532536

DOI: 10.1023/b:nere.0000042207.05071.ea

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8510497

Title: Identification of a neuron-specific promoter of human aromatic L-amino acid decarboxylase gene.

PubMed ID: 8510497

DOI: 10.1016/0169-328x(93)90006-b

PubMed ID: 1395716

Title: Localisation of the gene for human aromatic L-amino acid decarboxylase (DDC) to chromosome 7p13-->p11 by in situ hybridisation.

PubMed ID: 1395716

DOI: 10.1159/000133384

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 22143761

Title: Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases.

PubMed ID: 22143761

DOI: 10.1073/pnas.1111456108

PubMed ID: 10391209

Title: Characterization of single-nucleotide polymorphisms in coding regions of human genes.

PubMed ID: 10391209

DOI: 10.1038/10290

PubMed ID: 14991824

Title: Levodopa-responsive aromatic L-amino acid decarboxylase deficiency.

PubMed ID: 14991824

DOI: 10.1002/ana.20055

PubMed ID: 15079002

Title: Aromatic L-amino acid decarboxylase deficiency: clinical features, treatment, and prognosis.

PubMed ID: 15079002

DOI: 10.1212/wnl.62.7.1058

Sequence Information:

  • Length: 480
  • Mass: 53926
  • Checksum: 0A2CFF9A39BDE298
  • Sequence:
    • MNASEFRRRG KEMVDYMANY MEGIEGRQVY PDVEPGYLRP LIPAAAPQEP DTFEDIINDV 
EKIIMPGVTH WHSPYFFAYF PTASSYPAML ADMLCGAIGC IGFSWAASPA CTELETVMMD 
WLGKMLELPK AFLNEKAGEG GGVIQGSASE ATLVALLAAR TKVIHRLQAA SPELTQAAIM 
EKLVAYSSDQ AHSSVERAGL IGGVKLKAIP SDGNFAMRAS ALQEALERDK AAGLIPFFMV 
ATLGTTTCCS FDNLLEVGPI CNKEDIWLHV DAAYAGSAFI CPEFRHLLNG VEFADSFNFN 
PHKWLLVNFD CSAMWVKKRT DLTGAFRLDP TYLKHSHQDS GLITDYRHWQ IPLGRRFRSL 
KMWFVFRMYG VKGLQAYIRK HVQLSHEFES LVRQDPRFEI CVEVILGLVC FRLKGSNKVN 
EALLQRINSA KKIHLVPCHL RDKFVLRFAI CSRTVESAHV QRAWEHIKEL AADVLRAERE

Genular Protein ID: 3985871827

Symbol: A0A087WV24_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WV24

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 2 GeneTree 1 HGNC 1 InterPro 6 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 1 PROSITE 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 442
  • Mass: 49697
  • Checksum: 5CC2298848EFE098
  • Sequence:
    • MNASEFRRRG KEMVDYMANY MEGIEGRQVY PDVEPGYLRP LIPAAAPQEP DTFEDIINDV 
EKIIMPGAAS PACTELETVM MDWLGKMLEL PKAFLNEKAG EGGGVIQGSA SEATLVALLA 
ARTKVIHRLQ AASPELTQAA IMEKLVAYSS DQAHSSVERA GLIGGVKLKA IPSDGNFAMR 
ASALQEALER DKAAGLIPFF MVATLGTTTC CSFDNLLEVG PICNKEDIWL HVDAAYAGSA 
FICPEFRHLL NGVEFADSFN FNPHKWLLVN FDCSAMWVKK RTDLTGAFRL DPTYLKHSHQ 
DSGLITDYRH WQIPLGRRFR SLKMWFVFRM YGVKGLQAYI RKHVQLSHEF ESLVRQDPRF 
EICVEVILGL VCFRLKGSNK VNEALLQRIN SAKKIHLVPC HLRDKFVLRF AICSRTVESA 
HVQRAWEHIK ELAADVLRAE RE

Genular Protein ID: 3803880510

Symbol: Q53Y41_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q53Y41

Database IDs:

ARBA 11 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 6 GO 5 Gene3D 3 InterPro 6 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 1 PRINTS 1 PROSITE 1 Pfam 1 PharmGKB 1 RefSeq 2 RuleBase 1 SMR 1 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

Sequence Information:

  • Length: 480
  • Mass: 53894
  • Checksum: 898FD4B99A96C13E
  • Sequence:
    • MNASEFRRRG KEMVDYVANY MEGIEGRQVY PDVEPGYLRP LIPAAAPQEP DTFEDIINDV 
EKIIMPGVTH WHSPYFFAYF PTASSYPAML ADMLCGAIGC IGFSWAASPA CTELETVMMD 
WLGKMLELPK AFLNEKAGEG GGVIQGSASE ATLVALLAAR TKVIHRLQAA SPELTQAAIM 
EKLVAYSSDQ AHSSVERAGL IGGVKLKAIP SDGNFAMRAS ALQEALERDK AAGLIPFFMV 
ATLGTTTCCS FDNLLEVGPI CNKEDIWLHV DAAYAGSAFI CPEFRHLLNG VEFADSFNFN 
PHKWLLVNFD CSAMWVKKRT DLTGAFRLDP TYLKHSHQDS GLITDYRHWQ IPLGRRFRSL 
KMWFVFRMYG VKGLQAYIRK HVQLSHEFES LVRQDPRFEI CVEVILGLVC FRLKGSNKVN 
EALLQRINSA KKIHLVPCHL RDKFVLRFAI CSRTVESAHV QRAWEHIKEL AADVLRAERE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.