Details for: DDC
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: retinal rod cell (CL0000604)
Fold Change: 2.84
Marker Score: 8,102 - Cell Name: sympathetic neuron (CL0011103)
Fold Change: 2.7
Marker Score: 891 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 2.64
Marker Score: 788 - Cell Name: chromaffin cell (CL0000166)
Fold Change: 2.16
Marker Score: 3,036 - Cell Name: enterocyte of colon (CL1000347)
Fold Change: 1.92
Marker Score: 2,958 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 1.84
Marker Score: 6,533 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 1.83
Marker Score: 18,894 - Cell Name: type G enteroendocrine cell (CL0000508)
Fold Change: 1.69
Marker Score: 581 - Cell Name: enterocyte (CL0000584)
Fold Change: 1.67
Marker Score: 8,011 - Cell Name: stem cell (CL0000034)
Fold Change: 1.65
Marker Score: 3,926 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 1.54
Marker Score: 3,633 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 1.37
Marker Score: 868 - Cell Name: enterocyte of epithelium proper of ileum (CL1000342)
Fold Change: 1.33
Marker Score: 383 - Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: 1.28
Marker Score: 482 - Cell Name: precursor cell (CL0011115)
Fold Change: 1.22
Marker Score: 296 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 1.2
Marker Score: 3,757 - Cell Name: hepatoblast (CL0005026)
Fold Change: 1.12
Marker Score: 3,675 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.03
Marker Score: 1,951 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,819 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,043 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.99
Marker Score: 508 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,407 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.98
Marker Score: 461 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.96
Marker Score: 1,551 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,412 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.94
Marker Score: 5,353 - Cell Name: neural cell (CL0002319)
Fold Change: 0.93
Marker Score: 451 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,740 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9
Marker Score: 325 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.89
Marker Score: 885 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,285 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 0.87
Marker Score: 454 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.84
Marker Score: 644 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.83
Marker Score: 13,040 - Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 0.83
Marker Score: 431 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.8
Marker Score: 320 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.77
Marker Score: 750 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 395 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.76
Marker Score: 3,195 - Cell Name: brush cell (CL0002204)
Fold Change: 0.74
Marker Score: 677 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.73
Marker Score: 466 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.69
Marker Score: 178 - Cell Name: endocrine cell (CL0000163)
Fold Change: 0.69
Marker Score: 356 - Cell Name: progenitor cell of endocrine pancreas (CL0002351)
Fold Change: 0.65
Marker Score: 142 - Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 0.65
Marker Score: 261 - Cell Name: kidney cell (CL1000497)
Fold Change: 0.64
Marker Score: 426 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.64
Marker Score: 1,295 - Cell Name: intestine goblet cell (CL0019031)
Fold Change: 0.63
Marker Score: 604 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.61
Marker Score: 151 - Cell Name: type I enteroendocrine cell (CL0002277)
Fold Change: 0.56
Marker Score: 140 - Cell Name: common myeloid progenitor (CL0000049)
Fold Change: 0.56
Marker Score: 148 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.55
Marker Score: 441 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.51
Marker Score: 132 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.49
Marker Score: 154 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 0.48
Marker Score: 287 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.46
Marker Score: 277 - Cell Name: type EC enteroendocrine cell (CL0000577)
Fold Change: 0.46
Marker Score: 435 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.45
Marker Score: 209 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: 0.43
Marker Score: 188 - Cell Name: paneth cell (CL0000510)
Fold Change: 0.43
Marker Score: 300 - Cell Name: M cell of gut (CL0000682)
Fold Change: 0.41
Marker Score: 107 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.41
Marker Score: 194 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.4
Marker Score: 397 - Cell Name: epithelial cell of nephron (CL1000449)
Fold Change: 0.4
Marker Score: 835 - Cell Name: type L enteroendocrine cell (CL0002279)
Fold Change: 0.4
Marker Score: 108 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.39
Marker Score: 126 - Cell Name: mast cell (CL0000097)
Fold Change: 0.38
Marker Score: 218 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.36
Marker Score: 151 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.35
Marker Score: 201 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 0.34
Marker Score: 2,186 - Cell Name: acinar cell (CL0000622)
Fold Change: 0.34
Marker Score: 239 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 0.32
Marker Score: 321 - Cell Name: goblet cell (CL0000160)
Fold Change: 0.3
Marker Score: 1,989 - Cell Name: epithelial fate stem cell (CL0000036)
Fold Change: 0.29
Marker Score: 84 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.28
Marker Score: 245 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.28
Marker Score: 125 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 0.28
Marker Score: 149 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: 0.28
Marker Score: 116 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 0.26
Marker Score: 78 - Cell Name: lung neuroendocrine cell (CL1000223)
Fold Change: 0.26
Marker Score: 72 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 0.25
Marker Score: 565 - Cell Name: blood vessel endothelial cell (CL0000071)
Fold Change: 0.24
Marker Score: 243 - Cell Name: epithelial cell (CL0000066)
Fold Change: 0.22
Marker Score: 353 - Cell Name: parietal epithelial cell (CL1000452)
Fold Change: 0.21
Marker Score: 78 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 0.21
Marker Score: 924 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.21
Marker Score: 151 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.21
Marker Score: 438 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.21
Marker Score: 59 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 0.2
Marker Score: 60 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.2
Marker Score: 133 - Cell Name: enteric neuron (CL0007011)
Fold Change: 0.2
Marker Score: 106 - Cell Name: OFF retinal ganglion cell (CL4023033)
Fold Change: 0.2
Marker Score: 82 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 0.19
Marker Score: 65 - Cell Name: type D enteroendocrine cell (CL0000502)
Fold Change: 0.19
Marker Score: 58 - Cell Name: ON-bipolar cell (CL0000749)
Fold Change: 0.18
Marker Score: 537 - Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 0.18
Marker Score: 84 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: 0.18
Marker Score: 67 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: 0.17
Marker Score: 513 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.17
Marker Score: 1,103 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 0.17
Marker Score: 690
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4071522668
Symbol: DDC_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2590185
Title: Isolation and characterization of a cDNA clone encoding human aromatic L-amino acid decarboxylase.
PubMed ID: 2590185
PubMed ID: 1612608
Title: Human dopa decarboxylase: localization to human chromosome 7p11 and characterization of hepatic cDNAs.
PubMed ID: 1612608
PubMed ID: 1540578
Title: Molecular cloning of genomic DNA and chromosomal assignment of the gene for human aromatic L-amino acid decarboxylase, the enzyme for catecholamine and serotonin biosynthesis.
PubMed ID: 1540578
DOI: 10.1021/bi00123a004
PubMed ID: 15532536
Title: Identification and characterization of a novel form of the human L-dopa decarboxylase mRNA.
PubMed ID: 15532536
PubMed ID: 12853948
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8510497
Title: Identification of a neuron-specific promoter of human aromatic L-amino acid decarboxylase gene.
PubMed ID: 8510497
PubMed ID: 1395716
Title: Localisation of the gene for human aromatic L-amino acid decarboxylase (DDC) to chromosome 7p13-->p11 by in situ hybridisation.
PubMed ID: 1395716
DOI: 10.1159/000133384
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 22143761
Title: Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases.
PubMed ID: 22143761
PubMed ID: 10391209
Title: Characterization of single-nucleotide polymorphisms in coding regions of human genes.
PubMed ID: 10391209
DOI: 10.1038/10290
PubMed ID: 14991824
Title: Levodopa-responsive aromatic L-amino acid decarboxylase deficiency.
PubMed ID: 14991824
DOI: 10.1002/ana.20055
PubMed ID: 15079002
Title: Aromatic L-amino acid decarboxylase deficiency: clinical features, treatment, and prognosis.
PubMed ID: 15079002
Sequence Information:
- Length: 480
- Mass: 53926
- Checksum: 0A2CFF9A39BDE298
- Sequence:
MNASEFRRRG KEMVDYMANY MEGIEGRQVY PDVEPGYLRP LIPAAAPQEP DTFEDIINDV EKIIMPGVTH WHSPYFFAYF PTASSYPAML ADMLCGAIGC IGFSWAASPA CTELETVMMD WLGKMLELPK AFLNEKAGEG GGVIQGSASE ATLVALLAAR TKVIHRLQAA SPELTQAAIM EKLVAYSSDQ AHSSVERAGL IGGVKLKAIP SDGNFAMRAS ALQEALERDK AAGLIPFFMV ATLGTTTCCS FDNLLEVGPI CNKEDIWLHV DAAYAGSAFI CPEFRHLLNG VEFADSFNFN PHKWLLVNFD CSAMWVKKRT DLTGAFRLDP TYLKHSHQDS GLITDYRHWQ IPLGRRFRSL KMWFVFRMYG VKGLQAYIRK HVQLSHEFES LVRQDPRFEI CVEVILGLVC FRLKGSNKVN EALLQRINSA KKIHLVPCHL RDKFVLRFAI CSRTVESAHV QRAWEHIKEL AADVLRAERE
Genular Protein ID: 3803880510
Symbol: Q53Y41_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
PubMed ID: 12690205
Title: Human chromosome 7: DNA sequence and biology.
PubMed ID: 12690205
PubMed ID: 37466248
Title: Human aromatic amino acid decarboxylase is an asymmetric and flexible enzyme: Implication in aromatic amino acid decarboxylase deficiency.
PubMed ID: 37466248
DOI: 10.1002/pro.4732
Sequence Information:
- Length: 480
- Mass: 53894
- Checksum: 898FD4B99A96C13E
- Sequence:
MNASEFRRRG KEMVDYVANY MEGIEGRQVY PDVEPGYLRP LIPAAAPQEP DTFEDIINDV EKIIMPGVTH WHSPYFFAYF PTASSYPAML ADMLCGAIGC IGFSWAASPA CTELETVMMD WLGKMLELPK AFLNEKAGEG GGVIQGSASE ATLVALLAAR TKVIHRLQAA SPELTQAAIM EKLVAYSSDQ AHSSVERAGL IGGVKLKAIP SDGNFAMRAS ALQEALERDK AAGLIPFFMV ATLGTTTCCS FDNLLEVGPI CNKEDIWLHV DAAYAGSAFI CPEFRHLLNG VEFADSFNFN PHKWLLVNFD CSAMWVKKRT DLTGAFRLDP TYLKHSHQDS GLITDYRHWQ IPLGRRFRSL KMWFVFRMYG VKGLQAYIRK HVQLSHEFES LVRQDPRFEI CVEVILGLVC FRLKGSNKVN EALLQRINSA KKIHLVPCHL RDKFVLRFAI CSRTVESAHV QRAWEHIKEL AADVLRAERE
Genular Protein ID: 3985871827
Symbol: A0A087WV24_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 12853948
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
Sequence Information:
- Length: 442
- Mass: 49697
- Checksum: 5CC2298848EFE098
- Sequence:
MNASEFRRRG KEMVDYMANY MEGIEGRQVY PDVEPGYLRP LIPAAAPQEP DTFEDIINDV EKIIMPGAAS PACTELETVM MDWLGKMLEL PKAFLNEKAG EGGGVIQGSA SEATLVALLA ARTKVIHRLQ AASPELTQAA IMEKLVAYSS DQAHSSVERA GLIGGVKLKA IPSDGNFAMR ASALQEALER DKAAGLIPFF MVATLGTTTC CSFDNLLEVG PICNKEDIWL HVDAAYAGSA FICPEFRHLL NGVEFADSFN FNPHKWLLVN FDCSAMWVKK RTDLTGAFRL DPTYLKHSHQ DSGLITDYRH WQIPLGRRFR SLKMWFVFRM YGVKGLQAYI RKHVQLSHEF ESLVRQDPRF EICVEVILGL VCFRLKGSNK VNEALLQRIN SAKKIHLVPC HLRDKFVLRF AICSRTVESA HVQRAWEHIK ELAADVLRAE RE
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.