Details for: DLG3
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 150.1814
Cell Significance Index: -23.3600 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 91.3684
Cell Significance Index: -23.1800 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 46.3623
Cell Significance Index: -18.8400 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 19.7645
Cell Significance Index: -18.8700 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 18.9382
Cell Significance Index: -23.3500 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 8.6193
Cell Significance Index: -23.0900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 2.8992
Cell Significance Index: 200.5000 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.7990
Cell Significance Index: 177.9700 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 1.6271
Cell Significance Index: 97.6800 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.3311
Cell Significance Index: 144.7800 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.2657
Cell Significance Index: 57.3700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.1164
Cell Significance Index: 223.9400 - Cell Name: peg cell (CL4033014)
Fold Change: 1.0542
Cell Significance Index: 24.3600 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.0137
Cell Significance Index: 15.1900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.9199
Cell Significance Index: 19.9300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.8350
Cell Significance Index: 135.8100 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.7818
Cell Significance Index: 40.6100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.7384
Cell Significance Index: 21.2800 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.7097
Cell Significance Index: 17.0200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.6581
Cell Significance Index: 40.4500 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.6433
Cell Significance Index: 127.6700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.6210
Cell Significance Index: 17.7200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.6070
Cell Significance Index: 28.3000 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.6020
Cell Significance Index: 33.7800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.5985
Cell Significance Index: 14.9600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.5640
Cell Significance Index: 202.3100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.4160
Cell Significance Index: 27.9700 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.3987
Cell Significance Index: 8.7300 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3880
Cell Significance Index: 211.9100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2969
Cell Significance Index: 53.5200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.2904
Cell Significance Index: 200.8500 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.2787
Cell Significance Index: 7.7900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.2615
Cell Significance Index: 11.5700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.2601
Cell Significance Index: 44.4100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.2471
Cell Significance Index: 30.3800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.2337
Cell Significance Index: 8.8500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.2262
Cell Significance Index: 7.9500 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.2249
Cell Significance Index: 4.7900 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.2227
Cell Significance Index: 3.1700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.2155
Cell Significance Index: 16.5400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1356
Cell Significance Index: 122.4200 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.0980
Cell Significance Index: 18.6500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0939
Cell Significance Index: 41.5300 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0177
Cell Significance Index: 2.2700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.0152
Cell Significance Index: 11.1100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0119
Cell Significance Index: 22.4900 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0054
Cell Significance Index: 2.4600 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0053
Cell Significance Index: 8.0900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0032
Cell Significance Index: 5.8200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0013
Cell Significance Index: 0.7900 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0066
Cell Significance Index: -4.1100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0093
Cell Significance Index: -6.9100 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0098
Cell Significance Index: -1.3500 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0149
Cell Significance Index: -20.2100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0171
Cell Significance Index: -12.9200 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0249
Cell Significance Index: -14.0300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0270
Cell Significance Index: -3.9200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0286
Cell Significance Index: -0.4900 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.0299
Cell Significance Index: -0.6400 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0528
Cell Significance Index: -1.4100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0565
Cell Significance Index: -11.9100 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0584
Cell Significance Index: -1.8700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0608
Cell Significance Index: -0.8300 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.0642
Cell Significance Index: -7.3300 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0646
Cell Significance Index: -18.6000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0647
Cell Significance Index: -7.4100 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0692
Cell Significance Index: -8.0600 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0699
Cell Significance Index: -3.2900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1193
Cell Significance Index: -12.1900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1275
Cell Significance Index: -16.4700 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -0.1366
Cell Significance Index: -1.3000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.1412
Cell Significance Index: -8.9000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1499
Cell Significance Index: -11.1700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1506
Cell Significance Index: -17.7600 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1558
Cell Significance Index: -11.0200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1738
Cell Significance Index: -4.7300 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: -0.1755
Cell Significance Index: -1.7700 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.1757
Cell Significance Index: -13.9100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1982
Cell Significance Index: -20.6400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.2668
Cell Significance Index: -17.2100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2756
Cell Significance Index: -14.4700 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.3032
Cell Significance Index: -18.5900 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.3277
Cell Significance Index: -17.0700 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: -0.3354
Cell Significance Index: -3.4600 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: -0.3574
Cell Significance Index: -2.3300 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.3694
Cell Significance Index: -7.8400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3862
Cell Significance Index: -12.3000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3870
Cell Significance Index: -12.6700 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.4069
Cell Significance Index: -10.7000 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.4403
Cell Significance Index: -4.0600 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.4420
Cell Significance Index: -8.7400 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.4473
Cell Significance Index: -8.9800 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.4488
Cell Significance Index: -3.7700 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.4679
Cell Significance Index: -16.2600 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.4690
Cell Significance Index: -9.7300 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.4863
Cell Significance Index: -17.8500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.5020
Cell Significance Index: -12.9100 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.5147
Cell Significance Index: -11.1200 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.5233
Cell Significance Index: -15.3700 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.5315
Cell Significance Index: -18.6200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3189669499
Symbol: DLG3_HUMAN
Name: Disks large homolog 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9188857
Title: Cloning and characterization of NE-dlg: a novel human homolog of the Drosophila discs large (dlg) tumor suppressor protein interacts with the APC protein.
PubMed ID: 9188857
PubMed ID: 10574462
Title: Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
PubMed ID: 10574462
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15772651
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9278515
PubMed ID: 10725395
Title: The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses.
PubMed ID: 10725395
PubMed ID: 15185169
Title: Mutations in the DLG3 gene cause nonsyndromic X-linked mental retardation.
PubMed ID: 15185169
DOI: 10.1086/422703
PubMed ID: 16630835
Title: SALM synaptic cell adhesion-like molecules regulate the differentiation of excitatory synapses.
PubMed ID: 16630835
PubMed ID: 19118189
Title: Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis.
PubMed ID: 19118189
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 817
- Mass: 90314
- Checksum: CE125E9BEE3EEC66
- Sequence:
MHKHQHCCKC PECYEVTRLA ALRRLEPPGY GDWQVPDPYG PGGGNGASAG YGGYSSQTLP SQAGATPTPR TKAKLIPTGR DVGPVPPKPV PGKSTPKLNG SGPSWWPECT CTNRDWYEQV NGSDGMFKYE EIVLERGNSG LGFSIAGGID NPHVPDDPGI FITKIIPGGA AAMDGRLGVN DCVLRVNEVD VSEVVHSRAV EALKEAGPVV RLVVRRRQPP PETIMEVNLL KGPKGLGFSI AGGIGNQHIP GDNSIYITKI IEGGAAQKDG RLQIGDRLLA VNNTNLQDVR HEEAVASLKN TSDMVYLKVA KPGSLHLNDM YAPPDYASTF TALADNHISH NSSLGYLGAV ESKVSYPAPP QVPPTRYSPI PRHMLAEEDF TREPRKIILH KGSTGLGFNI VGGEDGEGIF VSFILAGGPA DLSGELRRGD RILSVNGVNL RNATHEQAAA ALKRAGQSVT IVAQYRPEEY SRFESKIHDL REQMMNSSMS SGSGSLRTSE KRSLYVRALF DYDRTRDSCL PSQGLSFSYG DILHVINASD DEWWQARLVT PHGESEQIGV IPSKKRVEKK ERARLKTVKF HARTGMIESN RDFPGLSDDY YGAKNLKGQE DAILSYEPVT RQEIHYARPV IILGPMKDRV NDDLISEFPH KFGSCVPHTT RPRRDNEVDG QDYHFVVSRE QMEKDIQDNK FIEAGQFNDN LYGTSIQSVR AVAERGKHCI LDVSGNAIKR LQQAQLYPIA IFIKPKSIEA LMEMNRRQTY EQANKIYDKA MKLEQEFGEY FTAIVQGDSL EEIYNKIKQI IEDQSGHYIW VPSPEKL
Genular Protein ID: 998630435
Symbol: Q59FY1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 917
- Mass: 99796
- Checksum: DFF5EAD57A2C1196
- Sequence:
APASSLPLGL GPEATTGDTE PPVLEGEPWV RGSVGAEAPG RPPGPRPRSA RAPPRVPPPS WSEQCECARE PGGGGGGGGG GGGGVESGVG WGVRAAGGSA MHKHQHCCKC PECYEVTRLA ALRRLEPPGY GDWQVPDPYG PGGGNGASAG YGGYSSQTLP SQAGATPTPR TKAKLIPTGR DVGPVPPKPV PGKSTPKLNG SGPSWWPECT CTNRDWYEQV NGSDGMFKYE EIVLERGNSG LGFSIAGGID NPHVPDDPGI FITKIIPGGA AAMDGRLGVN DCVLRVNEVD VSEVVHSRAV EALKEAGPVV RLVVRRRQPP PETIMEVNLL KGPKGLGFSI AGGIGNQHIP GDNSIYITKI IEGGAAQKDG RLQIGDRLLA VNNTNLQDVR HEEAVASLKN TSDMVYLKVA KPGSLHLNDM YAPPDYASTF TALADNHISH NSSLGYLGAV ESKVSYPAPP QVPPTRYSPI PRHMLAEEDF TREPRKIILH KGSTGLGFNI VGGEDGEGIF VSFILAGGPA DLSGELRRGD RILSVNGVNL RNATHEQAAA ALKRAGQSVT IVAQYRPEEY SRFESKIHDL REQMMNSSMS SGSGSLRTSE KRSLYVRALF DYDRTRDSCL PSQGLSFSYG DILHVINASD DEWWQARLVT PHGESEQIGV IPSKKRVEKK ERARLKTVKF HARTGMIESN RDFPGLSDDY YGAKNLKGQE DAILSYEPVT RQEIHYARPV IILGPMKDRV NDDLISEFPH KFGSCVPHTT RPRRDNEVDG QDYHFVVSRE QMEKDIQDNK FIEAGQFNDN LYGTSIQSVR AVAERGKHCI LDVSGNAIKR LQQAQLYPIA IFIKPKSIEA LMEMNRRQTY EQANKIYDKA MKLEQEFGEY FTAIVQGDSL EEIYNKIKQI IEDQSGHYIW VPSPEKL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.