Gene DSG2 - ENSG00000046604 | NCBI Gene ID: 1829

Details for: DSG2

Gene ID: 1829

Symbol: DSG2

Ensembl ID: ENSG00000046604

Description: desmoglein 2

Associated with

Apoptosis
(R-HSA-109581)
Apoptotic cleavage of cell adhesion proteins
(R-HSA-351906)
Apoptotic cleavage of cellular proteins
(R-HSA-111465)
Apoptotic execution phase
(R-HSA-75153)
Developmental biology
(R-HSA-1266738)
Formation of the cornified envelope
(R-HSA-6809371)
Keratinization
(R-HSA-6805567)
Programmed cell death
(R-HSA-5357801)
Rac2 gtpase cycle
(R-HSA-9013404)
Rac3 gtpase cycle
(R-HSA-9013423)
Rhog gtpase cycle
(R-HSA-9013408)
Rho gtpase cycle
(R-HSA-9012999)
Signaling by rho gtpases
(R-HSA-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-HSA-9716542)
Signal transduction
(R-HSA-162582)
Apical plasma membrane
(GO:0016324)
Bundle of his cell-purkinje myocyte adhesion involved in cell communication
(GO:0086073)
Calcium ion binding
(GO:0005509)
Cell-cell adhesion
(GO:0098609)
Cell-cell junction
(GO:0005911)
Cell adhesion
(GO:0007155)
Cell adhesion molecule binding
(GO:0050839)
Cell adhesive protein binding involved in bundle of his cell-purkinje myocyte communication
(GO:0086083)
Cell junction
(GO:0030054)
Cell surface
(GO:0009986)
Cornified envelope
(GO:0001533)
Desmosome
(GO:0030057)
Desmosome organization
(GO:0002934)
Extracellular exosome
(GO:0070062)
Homophilic cell adhesion via plasma membrane adhesion molecules
(GO:0007156)
Intercalated disc
(GO:0014704)
Intracellular membrane-bounded organelle
(GO:0043231)
Lateral plasma membrane
(GO:0016328)
Maternal process involved in female pregnancy
(GO:0060135)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Purkinje myocyte development
(GO:0003165)
Regulation of heart rate by cardiac conduction
(GO:0086091)
Regulation of ventricular cardiac muscle cell action potential
(GO:0098911)
Response to progesterone
(GO:0032570)

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: kidney collecting duct intercalated cell (CL1001432)
Fold Change: 2.71
Marker Score: 4487
Cell Name: renal intercalated cell (CL0005010)
Fold Change: 2.42
Marker Score: 1293
Cell Name: colon epithelial cell (CL0011108)
Fold Change: 2.39
Marker Score: 7520
Cell Name: double negative thymocyte (CL0002489)
Fold Change: 2.16
Marker Score: 2974
Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 2.15
Marker Score: 3169
Cell Name: enterocyte (CL0000584)
Fold Change: 2.11
Marker Score: 10104.5
Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 2.06
Marker Score: 3646
Cell Name: stem cell (CL0000034)
Fold Change: 2.04
Marker Score: 4849
Cell Name: double-positive, alpha-beta thymocyte (CL0000809)
Fold Change: 2.01
Marker Score: 3941
Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 1.96
Marker Score: 1547.5
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.94
Marker Score: 4419
Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 1.93
Marker Score: 1018.5
Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 1.91
Marker Score: 12166
Cell Name: intestine goblet cell (CL0019031)
Fold Change: 1.83
Marker Score: 1754
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: 1.66
Marker Score: 1723
Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
Fold Change: 1.62
Marker Score: 4352
Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: 1.62
Marker Score: 611
Cell Name: cell in vitro (CL0001034)
Fold Change: 1.55
Marker Score: 53730
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 1.55
Marker Score: 1628
Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 1.53
Marker Score: 11381.5
Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 1.52
Marker Score: 1217.5
Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.49
Marker Score: 5850
Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168334
Cell Name: endothelial cell of sinusoid (CL0002262)
Fold Change: 1.46
Marker Score: 353
Cell Name: myoepithelial cell of mammary gland (CL0002324)
Fold Change: 1.41
Marker Score: 6931
Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 1.4
Marker Score: 815
Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.38
Marker Score: 1377.5
Cell Name: duct epithelial cell (CL0000068)
Fold Change: 1.37
Marker Score: 639
Cell Name: mammary gland epithelial cell (CL0002327)
Fold Change: 1.33
Marker Score: 473
Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 1.31
Marker Score: 874
Cell Name: acinar cell (CL0000622)
Fold Change: 1.26
Marker Score: 889
Cell Name: glandular cell of esophagus (CL0002657)
Fold Change: 1.26
Marker Score: 399
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 1.25
Marker Score: 3049
Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.25
Marker Score: 4617
Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.22
Marker Score: 2576
Cell Name: type G enteroendocrine cell (CL0000508)
Fold Change: 1.21
Marker Score: 417
Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
Fold Change: 1.19
Marker Score: 1263
Cell Name: basal cell (CL0000646)
Fold Change: 1.18
Marker Score: 1521
Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 1.15
Marker Score: 4803.5
Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.12
Marker Score: 278
Cell Name: enterocyte of colon (CL1000347)
Fold Change: 1.11
Marker Score: 1717
Cell Name: mucous neck cell (CL0000651)
Fold Change: 1.11
Marker Score: 2522
Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 1.09
Marker Score: 1795.5
Cell Name: secretory cell (CL0000151)
Fold Change: 1.06
Marker Score: 1942
Cell Name: kidney collecting duct principal cell (CL1001431)
Fold Change: 1.06
Marker Score: 2680
Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.04
Marker Score: 251771
Cell Name: epithelial cell (CL0000066)
Fold Change: 1.02
Marker Score: 1623
Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71790
Cell Name: type I pneumocyte (CL0002062)
Fold Change: 1
Marker Score: 1202
Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
Fold Change: 1
Marker Score: 1012
Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48014
Cell Name: Unknown (CL0002371)
Fold Change: 0.98
Marker Score: 1046
Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30406
Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.98
Marker Score: 505
Cell Name: kidney cell (CL1000497)
Fold Change: 0.98
Marker Score: 652
Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.97
Marker Score: 458
Cell Name: precursor cell (CL0011115)
Fold Change: 0.97
Marker Score: 235
Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2411
Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.95
Marker Score: 1540
Cell Name: mesothelial cell of epicardium (CL0011019)
Fold Change: 0.95
Marker Score: 304
Cell Name: type A enteroendocrine cell (CL0002067)
Fold Change: 0.94
Marker Score: 377
Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.93
Marker Score: 5330
Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: 0.93
Marker Score: 3300.5
Cell Name: pulmonary ionocyte (CL0017000)
Fold Change: 0.92
Marker Score: 564
Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.92
Marker Score: 264
Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 0.92
Marker Score: 718
Cell Name: granulosa cell (CL0000501)
Fold Change: 0.92
Marker Score: 9215
Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2741
Cell Name: paneth cell (CL0000510)
Fold Change: 0.91
Marker Score: 633
Cell Name: lung secretory cell (CL1000272)
Fold Change: 0.91
Marker Score: 810
Cell Name: PP cell (CL0000696)
Fold Change: 0.9
Marker Score: 203
Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.9
Marker Score: 323.5
Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 0.89
Marker Score: 258
Cell Name: kidney connecting tubule epithelial cell (CL1000768)
Fold Change: 0.89
Marker Score: 1264
Cell Name: primordial germ cell (CL0000670)
Fold Change: 0.88
Marker Score: 1104
Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5295
Cell Name: type II pneumocyte (CL0002063)
Fold Change: 0.87
Marker Score: 5652
Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.87
Marker Score: 13547
Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 0.85
Marker Score: 938
Cell Name: nephron tubule epithelial cell (CL1000494)
Fold Change: 0.85
Marker Score: 199
Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 0.84
Marker Score: 4429
Cell Name: taste receptor cell (CL0000209)
Fold Change: 0.84
Marker Score: 724
Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.82
Marker Score: 628
Cell Name: mesothelial cell (CL0000077)
Fold Change: 0.82
Marker Score: 329
Cell Name: lung ciliated cell (CL1000271)
Fold Change: 0.82
Marker Score: 388.5
Cell Name: epithelial cell of glomerular capsule (CL1000450)
Fold Change: 0.8
Marker Score: 205
Cell Name: papillary tips cell (CL1000597)
Fold Change: 0.8
Marker Score: 161
Cell Name: male germ cell (CL0000015)
Fold Change: 0.79
Marker Score: 228
Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 0.79
Marker Score: 433
Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 0.79
Marker Score: 293
Cell Name: pneumocyte (CL0000322)
Fold Change: 0.78
Marker Score: 1246
Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.77
Marker Score: 309
Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.76
Marker Score: 2068
Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 393
Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 0.76
Marker Score: 516
Cell Name: peptic cell (CL0000155)
Fold Change: 0.75
Marker Score: 316
Cell Name: club cell (CL0000158)
Fold Change: 0.74
Marker Score: 868
Cell Name: endocrine cell (CL0000163)
Fold Change: 0.74
Marker Score: 383
Cell Name: type L enteroendocrine cell (CL0002279)
Fold Change: 0.74
Marker Score: 202
Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
Fold Change: 0.74
Marker Score: 796.5

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**Key characteristics:** * The human homolog of the mouse desmoglein 2 gene is known as desmoglein 2 (DSG2). * It is a large protein with a molecular weight of approximately 120 kDa. * It is a transmembrane protein that is expressed in a variety of cell types, including epithelial cells, endothelial cells, and immune cells. * It is a key component of desmosomes, which are cell adhesion complexes that hold epithelial cells together and provide structural support for tissues. * It is also involved in cell signaling and migration. **Pathways and functions:** * Desmoglein 2 is involved in cell adhesion, migration, and signaling in epithelial tissues. * It is a key component of desmosomes, which are cell adhesion complexes that hold epithelial cells together and provide structural support for tissues. * It is also involved in cell signaling and migration. * It has been shown to play a role in the regulation of epithelial cell migration, proliferation, and differentiation. * It is also involved in the regulation of immune cell trafficking. **Clinical significance:** * Mutations in the DSG2 gene have been linked to several human diseases, including cancer, cardiovascular disease, and kidney disease. * These mutations can disrupt desmoglein 2 signaling, leading to cell adhesion defects and tissue disorganization. * Targeting the DSG2 gene has been explored as a therapeutic strategy for these diseases.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Desmoglein-2

Genular Protein ID: 790684932

Symbol: DSG2_HUMAN

Name: Desmoglein-2

UniProtKB Accession Codes:

Q14126 Q4KKU6

Database IDs:

Citations:

PubMed ID: 8143788

Title: Identification of the ubiquitous human desmoglein, Dsg2, and the expression catalogue of the desmoglein subfamily of desmosomal cadherins.

PubMed ID: 8143788

DOI: 10.1006/excr.1994.1103

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1935985

Title: Complete amino acid sequence of the epidermal desmoglein precursor polypeptide and identification of a second type of desmoglein gene.

PubMed ID: 1935985

PubMed ID: 11790773

Title: Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling.

PubMed ID: 11790773

DOI: 10.1074/jbc.m108765200

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 31402609

Title: S-acylated Golga7b stabilises DHHC5 at the plasma membrane to regulate cell adhesion.

PubMed ID: 31402609

DOI: 10.15252/embr.201847472

PubMed ID: 16773573

Title: DSG2 mutations contribute to arrhythmogenic right ventricular dysplasia/cardiomyopathy.

PubMed ID: 16773573

DOI: 10.1086/504393

PubMed ID: 18678517

Title: A missense variant in desmoglein-2 predisposes to dilated cardiomyopathy.

PubMed ID: 18678517

DOI: 10.1016/j.ymgme.2008.06.005

PubMed ID: 20031617

Title: Comprehensive desmosome mutation analysis in North Americans with arrhythmogenic right ventricular dysplasia/cardiomyopathy.

PubMed ID: 20031617

DOI: 10.1161/circgenetics.109.858217

PubMed ID: 19863551

Title: Role of genetic testing in arrhythmogenic right ventricular cardiomyopathy/dysplasia.

PubMed ID: 19863551

DOI: 10.1111/j.1399-0004.2009.01282.x

PubMed ID: 21062920

Title: Mechanistic insights into arrhythmogenic right ventricular cardiomyopathy caused by desmocollin-2 mutations.

PubMed ID: 21062920

DOI: 10.1093/cvr/cvq353

Sequence Information:

Length: 1118
Mass: 122294
Checksum: E1481AA1686DB80A
Sequence:

MARSPGRAYA LLLLLICFNV GSGLHLQVLS TRNENKLLPK HPHLVRQKRA WITAPVALRE 
GEDLSKKNPI AKIHSDLAEE RGLKITYKYT GKGITEPPFG IFVFNKDTGE LNVTSILDRE 
ETPFFLLTGY ALDARGNNVE KPLELRIKVL DINDNEPVFT QDVFVGSVEE LSAAHTLVMK 
INATDADEPN TLNSKISYRI VSLEPAYPPV FYLNKDTGEI YTTSVTLDRE EHSSYTLTVE 
ARDGNGEVTD KPVKQAQVQI RILDVNDNIP VVENKVLEGM VEENQVNVEV TRIKVFDADE 
IGSDNWLANF TFASGNEGGY FHIETDAQTN EGIVTLIKEV DYEEMKNLDF SVIVANKAAF 
HKSIRSKYKP TPIPIKVKVK NVKEGIHFKS SVISIYVSES MDRSSKGQII GNFQAFDEDT 
GLPAHARYVK LEDRDNWISV DSVTSEIKLA KLPDFESRYV QNGTYTVKIV AISEDYPRKT 
ITGTVLINVE DINDNCPTLI EPVQTICHDA EYVNVTAEDL DGHPNSGPFS FSVIDKPPGM 
AEKWKIARQE STSVLLQQSE KKLGRSEIQF LISDNQGFSC PEKQVLTLTV CECLHGSGCR 
EAQHDSYVGL GPAAIALMIL AFLLLLLVPL LLLMCHCGKG AKGFTPIPGT IEMLHPWNNE 
GAPPEDKVVP SFLPVDQGGS LVGRNGVGGM AKEATMKGSS SASIVKGQHE MSEMDGRWEE 
HRSLLSGRAT QFTGATGAIM TTETTKTARA TGASRDMAGA QAAAVALNEE FLRNYFTDKA 
ASYTEEDENH TAKDCLLVYS QEETESLNAS IGCCSFIEGE LDDRFLDDLG LKFKTLAEVC 
LGQKIDINKE IEQRQKPATE TSMNTASHSL CEQTMVNSEN TYSSGSSFPV PKSLQEANAE 
KVTQEIVTER SVSSRQAQKV ATPLPDPMAS RNVIATETSY VTGSTMPPTT VILGPSQPQS 
LIVTERVYAP ASTLVDQPYA NEGTVVVTER VIQPHGGGSN PLEGTQHLQD VPYVMVRERE 
SFLAPSSGVQ PTLAMPNIAV GQNVTVTERV LAPASTLQSS YQIPTENSMT ARNTTVSGAG 
VPGPLPDFGL EESGHSNSTI TTSSTRVTKH STVQHSYS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.

Details for: DSG2

Associated with

Cells (max top 100)

Other Information

Identification of the ubiquitous human desmoglein, Dsg2, and the expression catalogue of the desmoglein subfamily of desmosomal cadherins. PubMed ID: 8143788

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Complete amino acid sequence of the epidermal desmoglein precursor polypeptide and identification of a second type of desmoglein gene. PubMed ID: 1935985

Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling. PubMed ID: 11790773

Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. PubMed ID: 12754519

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. PubMed ID: 16335952

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. PubMed ID: 17081983

Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. PubMed ID: 18691976

A quantitative atlas of mitotic phosphorylation. PubMed ID: 18669648

Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry. PubMed ID: 19159218

A strategy for precise and large scale identification of core fucosylated glycoproteins. PubMed ID: 19139490

Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. PubMed ID: 19349973

Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. PubMed ID: 19690332

Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. PubMed ID: 20068231

Initial characterization of the human central proteome. PubMed ID: 21269460

System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. PubMed ID: 21406692

Toward a comprehensive characterization of a human cancer cell phosphoproteome. PubMed ID: 23186163

An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. PubMed ID: 24275569

S-acylated Golga7b stabilises DHHC5 at the plasma membrane to regulate cell adhesion. PubMed ID: 31402609

DSG2 mutations contribute to arrhythmogenic right ventricular dysplasia/cardiomyopathy. PubMed ID: 16773573

A missense variant in desmoglein-2 predisposes to dilated cardiomyopathy. PubMed ID: 18678517

Comprehensive desmosome mutation analysis in North Americans with arrhythmogenic right ventricular dysplasia/cardiomyopathy. PubMed ID: 20031617

Role of genetic testing in arrhythmogenic right ventricular cardiomyopathy/dysplasia. PubMed ID: 19863551

Mechanistic insights into arrhythmogenic right ventricular cardiomyopathy caused by desmocollin-2 mutations. PubMed ID: 21062920