Details for: DSG2

Gene ID: 1829

Symbol: DSG2

Ensembl ID: ENSG00000046604

Description: desmoglein 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 149.5385
    Cell Significance Index: -23.2600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 82.7934
    Cell Significance Index: -21.0000
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 55.1284
    Cell Significance Index: -22.7100
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 35.5502
    Cell Significance Index: -23.8600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 18.9463
    Cell Significance Index: -23.3600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 9.9595
    Cell Significance Index: -26.6800
  • Cell Name: columnar/cuboidal epithelial cell (CL0000075)
    Fold Change: 8.3965
    Cell Significance Index: 32.1500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 4.5616
    Cell Significance Index: 236.9600
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 3.6132
    Cell Significance Index: 36.4500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 3.1355
    Cell Significance Index: 142.1200
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.9907
    Cell Significance Index: 27.5400
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 2.2904
    Cell Significance Index: 34.3200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.1976
    Cell Significance Index: 59.8200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.1366
    Cell Significance Index: 61.5600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 1.8903
    Cell Significance Index: 307.4400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.8172
    Cell Significance Index: 197.6600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 1.6410
    Cell Significance Index: 41.0200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.6364
    Cell Significance Index: 201.2200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 1.5580
    Cell Significance Index: 41.6000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.5244
    Cell Significance Index: 150.8000
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 1.4510
    Cell Significance Index: 8.9300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.1165
    Cell Significance Index: 201.2700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.0585
    Cell Significance Index: 201.4300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.0378
    Cell Significance Index: 566.7700
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 0.9431
    Cell Significance Index: 5.8600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.8676
    Cell Significance Index: 40.7800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.8146
    Cell Significance Index: 37.9800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.8090
    Cell Significance Index: 17.2300
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.7899
    Cell Significance Index: 18.2500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7659
    Cell Significance Index: 151.9900
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 0.7501
    Cell Significance Index: 2.8300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.7286
    Cell Significance Index: 94.1300
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.6755
    Cell Significance Index: 6.9900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.5821
    Cell Significance Index: 99.3900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5225
    Cell Significance Index: 231.0000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.5200
    Cell Significance Index: 36.7800
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.4182
    Cell Significance Index: 6.4700
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.2759
    Cell Significance Index: 9.7000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2547
    Cell Significance Index: 18.9800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2343
    Cell Significance Index: 6.1600
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.2004
    Cell Significance Index: 1.6000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.1841
    Cell Significance Index: 5.9000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1755
    Cell Significance Index: 13.4700
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.1602
    Cell Significance Index: 18.2900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0535
    Cell Significance Index: 39.2400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0220
    Cell Significance Index: 41.4400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0136
    Cell Significance Index: 0.3800
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0085
    Cell Significance Index: 6.4700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0068
    Cell Significance Index: 0.9400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.0011
    Cell Significance Index: 0.7900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0010
    Cell Significance Index: 1.9200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0055
    Cell Significance Index: -3.5000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0064
    Cell Significance Index: -9.8700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0155
    Cell Significance Index: -9.7100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0168
    Cell Significance Index: -22.9000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0196
    Cell Significance Index: -1.1000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0229
    Cell Significance Index: -2.6200
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0249
    Cell Significance Index: -0.3400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0270
    Cell Significance Index: -15.2500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0324
    Cell Significance Index: -3.3100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0342
    Cell Significance Index: -0.7400
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0401
    Cell Significance Index: -0.4200
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0484
    Cell Significance Index: -10.2000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0508
    Cell Significance Index: -18.2300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0530
    Cell Significance Index: -10.6300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0535
    Cell Significance Index: -24.2700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0645
    Cell Significance Index: -18.5700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0648
    Cell Significance Index: -9.4200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0798
    Cell Significance Index: -10.2300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0832
    Cell Significance Index: -9.7000
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.0936
    Cell Significance Index: -0.6800
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.2063
    Cell Significance Index: -1.2800
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.2143
    Cell Significance Index: -3.0500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2183
    Cell Significance Index: -25.7400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2231
    Cell Significance Index: -23.2300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.2510
    Cell Significance Index: -12.6900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2514
    Cell Significance Index: -19.9100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2806
    Cell Significance Index: -5.8200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2855
    Cell Significance Index: -4.2200
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.2955
    Cell Significance Index: -3.7900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3036
    Cell Significance Index: -10.5500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.3391
    Cell Significance Index: -13.9000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.3419
    Cell Significance Index: -22.9900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3751
    Cell Significance Index: -24.2000
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.3789
    Cell Significance Index: -4.8800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3822
    Cell Significance Index: -24.0900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3839
    Cell Significance Index: -23.5400
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.4005
    Cell Significance Index: -4.2300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.4067
    Cell Significance Index: -25.0000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.4227
    Cell Significance Index: -7.0800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.4380
    Cell Significance Index: -12.9000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.4852
    Cell Significance Index: -17.8100
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.5248
    Cell Significance Index: -8.8400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5509
    Cell Significance Index: -19.3000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.5563
    Cell Significance Index: -14.3000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.5629
    Cell Significance Index: -29.5600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.5648
    Cell Significance Index: -14.4300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.5943
    Cell Significance Index: -12.4400
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.6261
    Cell Significance Index: -10.5300
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.6301
    Cell Significance Index: -5.9900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** DSG2 is a transmembrane protein with four extracellular cadherin domains, which mediate homophilic cell-to-cell adhesion. The protein is composed of two domains, an extracellular domain and an intracellular domain, which interact with other desmoglein proteins and the cytoskeleton to maintain cell adhesion. DSG2 is also a calcium-binding protein, which is essential for the proper functioning of desmosomes. The protein is highly conserved across species, with high sequence identity to its mouse and zebrafish counterparts. **Pathways and Functions** DSG2 is involved in several cellular processes, including: 1. **Cell-to-cell adhesion**: DSG2 mediates homophilic cell-to-cell adhesion, which is essential for the maintenance of tissue structure and the prevention of cell migration. 2. **Desmosome formation**: DSG2 contributes to the formation of desmosomes, which are strong adhesion complexes that link adjacent cells together. 3. **Apoptosis regulation**: DSG2 is involved in the regulation of apoptosis, particularly in the context of programmed cell death in the skin. 4. **Cardiac conduction**: DSG2 regulates heart rate and cardiac conduction by interacting with other proteins and the cytoskeleton in cardiac tissue. 5. **Cell signaling**: DSG2 is involved in cell signaling pathways, including the Rac2 and Rac3 GTPase cycles, which regulate cell migration and proliferation. **Clinical Significance** DSG2 mutations have been associated with various diseases, including: 1. **Pemphigus**: DSG2 mutations can lead to pemphigus, a group of autoimmune diseases characterized by blistering skin lesions. 2. **Congenital skin disorders**: DSG2 mutations can also cause congenital skin disorders, such as epidermolysis bullosa simplex. 3. **Cardiac arrhythmias**: DSG2 mutations have been associated with cardiac arrhythmias, including atrial fibrillation and ventricular tachycardia. 4. **Cancer**: DSG2 is also involved in cancer development and progression, particularly in the context of skin and cardiac cancer. In summary, DSG2 is a critical protein that plays a key role in cell-to-cell adhesion, desmosome formation, and cardiac conduction. Mutations in this gene can lead to various diseases, highlighting the importance of DSG2 in maintaining tissue structure and function.

Genular Protein ID: 790684932

Symbol: DSG2_HUMAN

Name: Desmoglein-2

UniProtKB Accession Codes:

Q14126 Q4KKU6

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CPTAC 1 CTD 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 4 EMDB 8 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 24 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 4 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 12 PIR 1 PRINTS 3 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 6 RefSeq 1 SASBDB 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8143788

Title: Identification of the ubiquitous human desmoglein, Dsg2, and the expression catalogue of the desmoglein subfamily of desmosomal cadherins.

PubMed ID: 8143788

DOI: 10.1006/excr.1994.1103

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1935985

Title: Complete amino acid sequence of the epidermal desmoglein precursor polypeptide and identification of a second type of desmoglein gene.

PubMed ID: 1935985

PubMed ID: 11790773

Title: Protein binding and functional characterization of plakophilin 2. Evidence for its diverse roles in desmosomes and beta -catenin signaling.

PubMed ID: 11790773

DOI: 10.1074/jbc.m108765200

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 18691976

Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.

PubMed ID: 18691976

DOI: 10.1016/j.molcel.2008.07.007

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 20859650

Title: E-cadherin and plakoglobin recruit plakophilin3 to the cell border to initiate desmosome assembly.

PubMed ID: 20859650

DOI: 10.1007/s00018-010-0531-3

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25208567

Title: Plakophilin 3 mediates Rap1-dependent desmosome assembly and adherens junction maturation.

PubMed ID: 25208567

DOI: 10.1091/mbc.e14-05-0968

PubMed ID: 31402609

Title: S-acylated Golga7b stabilises DHHC5 at the plasma membrane to regulate cell adhesion.

PubMed ID: 31402609

DOI: 10.15252/embr.201847472

PubMed ID: 16773573

Title: DSG2 mutations contribute to arrhythmogenic right ventricular dysplasia/cardiomyopathy.

PubMed ID: 16773573

DOI: 10.1086/504393

PubMed ID: 18678517

Title: A missense variant in desmoglein-2 predisposes to dilated cardiomyopathy.

PubMed ID: 18678517

DOI: 10.1016/j.ymgme.2008.06.005

PubMed ID: 20031617

Title: Comprehensive desmosome mutation analysis in North Americans with arrhythmogenic right ventricular dysplasia/cardiomyopathy.

PubMed ID: 20031617

DOI: 10.1161/circgenetics.109.858217

PubMed ID: 19863551

Title: Role of genetic testing in arrhythmogenic right ventricular cardiomyopathy/dysplasia.

PubMed ID: 19863551

DOI: 10.1111/j.1399-0004.2009.01282.x

PubMed ID: 21062920

Title: Mechanistic insights into arrhythmogenic right ventricular cardiomyopathy caused by desmocollin-2 mutations.

PubMed ID: 21062920

DOI: 10.1093/cvr/cvq353

Sequence Information:

  • Length: 1118
  • Mass: 122294
  • Checksum: E1481AA1686DB80A
  • Sequence:
    • MARSPGRAYA LLLLLICFNV GSGLHLQVLS TRNENKLLPK HPHLVRQKRA WITAPVALRE 
GEDLSKKNPI AKIHSDLAEE RGLKITYKYT GKGITEPPFG IFVFNKDTGE LNVTSILDRE 
ETPFFLLTGY ALDARGNNVE KPLELRIKVL DINDNEPVFT QDVFVGSVEE LSAAHTLVMK 
INATDADEPN TLNSKISYRI VSLEPAYPPV FYLNKDTGEI YTTSVTLDRE EHSSYTLTVE 
ARDGNGEVTD KPVKQAQVQI RILDVNDNIP VVENKVLEGM VEENQVNVEV TRIKVFDADE 
IGSDNWLANF TFASGNEGGY FHIETDAQTN EGIVTLIKEV DYEEMKNLDF SVIVANKAAF 
HKSIRSKYKP TPIPIKVKVK NVKEGIHFKS SVISIYVSES MDRSSKGQII GNFQAFDEDT 
GLPAHARYVK LEDRDNWISV DSVTSEIKLA KLPDFESRYV QNGTYTVKIV AISEDYPRKT 
ITGTVLINVE DINDNCPTLI EPVQTICHDA EYVNVTAEDL DGHPNSGPFS FSVIDKPPGM 
AEKWKIARQE STSVLLQQSE KKLGRSEIQF LISDNQGFSC PEKQVLTLTV CECLHGSGCR 
EAQHDSYVGL GPAAIALMIL AFLLLLLVPL LLLMCHCGKG AKGFTPIPGT IEMLHPWNNE 
GAPPEDKVVP SFLPVDQGGS LVGRNGVGGM AKEATMKGSS SASIVKGQHE MSEMDGRWEE 
HRSLLSGRAT QFTGATGAIM TTETTKTARA TGASRDMAGA QAAAVALNEE FLRNYFTDKA 
ASYTEEDENH TAKDCLLVYS QEETESLNAS IGCCSFIEGE LDDRFLDDLG LKFKTLAEVC 
LGQKIDINKE IEQRQKPATE TSMNTASHSL CEQTMVNSEN TYSSGSSFPV PKSLQEANAE 
KVTQEIVTER SVSSRQAQKV ATPLPDPMAS RNVIATETSY VTGSTMPPTT VILGPSQPQS 
LIVTERVYAP ASTLVDQPYA NEGTVVVTER VIQPHGGGSN PLEGTQHLQD VPYVMVRERE 
SFLAPSSGVQ PTLAMPNIAV GQNVTVTERV LAPASTLQSS YQIPTENSMT ARNTTVSGAG 
VPGPLPDFGL EESGHSNSTI TTSSTRVTKH STVQHSYS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.