Details for: SLC29A1

Gene ID: 2030

Symbol: SLC29A1

Ensembl ID: ENSG00000112759

Description: solute carrier family 29 member 1 (Augustine blood group)

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 73.4102
    Cell Significance Index: -18.6200
  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 54.5179
    Cell Significance Index: -8.4800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 43.6751
    Cell Significance Index: -20.6200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 15.9130
    Cell Significance Index: -19.6200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.9915
    Cell Significance Index: -17.4900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.3091
    Cell Significance Index: -19.5800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 5.3547
    Cell Significance Index: -21.1300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 1.1923
    Cell Significance Index: 30.4600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.1199
    Cell Significance Index: 58.1800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.9624
    Cell Significance Index: 112.1600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.8251
    Cell Significance Index: 22.1100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.7183
    Cell Significance Index: 206.6900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6467
    Cell Significance Index: 105.1800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5794
    Cell Significance Index: 63.0200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.5135
    Cell Significance Index: 103.0000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.4603
    Cell Significance Index: 35.3300
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.4360
    Cell Significance Index: 4.7400
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.4310
    Cell Significance Index: 12.3600
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 0.3656
    Cell Significance Index: 6.4600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.3251
    Cell Significance Index: 19.5200
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 0.3100
    Cell Significance Index: 7.5700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.3018
    Cell Significance Index: 59.9000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.2885
    Cell Significance Index: 49.2700
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2747
    Cell Significance Index: 19.0000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2552
    Cell Significance Index: 91.5500
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2417
    Cell Significance Index: 6.3600
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.2238
    Cell Significance Index: 3.5500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2201
    Cell Significance Index: 21.7700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1816
    Cell Significance Index: 32.7500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.1636
    Cell Significance Index: 12.1900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.1498
    Cell Significance Index: 19.3500
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.1497
    Cell Significance Index: 7.8600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.1268
    Cell Significance Index: 5.9100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.1080
    Cell Significance Index: 2.3400
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 0.1058
    Cell Significance Index: 0.6900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1009
    Cell Significance Index: 11.9000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0905
    Cell Significance Index: 62.6200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0821
    Cell Significance Index: 15.6200
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0720
    Cell Significance Index: 31.8200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0658
    Cell Significance Index: 123.9700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0556
    Cell Significance Index: 6.8400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0424
    Cell Significance Index: 65.3000
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0359
    Cell Significance Index: 0.5300
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.0345
    Cell Significance Index: 0.1500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0332
    Cell Significance Index: 61.3100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0320
    Cell Significance Index: 17.4800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0125
    Cell Significance Index: 0.3600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0091
    Cell Significance Index: 0.4300
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0086
    Cell Significance Index: 0.2300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0058
    Cell Significance Index: 7.8400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0056
    Cell Significance Index: 0.3500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0045
    Cell Significance Index: 2.0300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0017
    Cell Significance Index: 0.0600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0044
    Cell Significance Index: -0.6000
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0047
    Cell Significance Index: -3.0100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0051
    Cell Significance Index: -3.8100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0107
    Cell Significance Index: -7.8600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0129
    Cell Significance Index: -1.3200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0131
    Cell Significance Index: -9.9400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0153
    Cell Significance Index: -0.7000
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0167
    Cell Significance Index: -10.4000
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0175
    Cell Significance Index: -1.2400
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0236
    Cell Significance Index: -0.4600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0243
    Cell Significance Index: -13.7300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0418
    Cell Significance Index: -8.8100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0493
    Cell Significance Index: -7.1700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0807
    Cell Significance Index: -10.3400
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0830
    Cell Significance Index: -9.4700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0863
    Cell Significance Index: -9.8900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1021
    Cell Significance Index: -6.5900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1033
    Cell Significance Index: -3.5900
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.1142
    Cell Significance Index: -0.6900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1291
    Cell Significance Index: -2.7500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1303
    Cell Significance Index: -2.1800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1443
    Cell Significance Index: -3.8600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1655
    Cell Significance Index: -17.2300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1798
    Cell Significance Index: -3.7300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1985
    Cell Significance Index: -12.2000
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.1988
    Cell Significance Index: -1.2400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2019
    Cell Significance Index: -8.9300
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2156
    Cell Significance Index: -1.9900
  • Cell Name: germ cell (CL0000586)
    Fold Change: -0.2159
    Cell Significance Index: -1.6300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.2209
    Cell Significance Index: -2.5100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2299
    Cell Significance Index: -18.2100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2589
    Cell Significance Index: -17.4100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2679
    Cell Significance Index: -10.1500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2860
    Cell Significance Index: -17.5400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.3242
    Cell Significance Index: -18.1900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.3285
    Cell Significance Index: -10.5200
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: -0.3462
    Cell Significance Index: -2.2100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.3616
    Cell Significance Index: -9.0400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3623
    Cell Significance Index: -11.5400
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.3666
    Cell Significance Index: -4.1500
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.3716
    Cell Significance Index: -6.2500
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.3750
    Cell Significance Index: -7.9600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.3801
    Cell Significance Index: -19.2100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.3836
    Cell Significance Index: -8.4000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.4096
    Cell Significance Index: -14.3500
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.4194
    Cell Significance Index: -5.2300
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.4270
    Cell Significance Index: -5.0900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Nucleoside Transporter:** SLC29A1 encodes for ENT1, a transporter that facilitates the uptake of nucleosides across cellular membranes. 2. **Widespread Expression:** The gene is expressed in various cell types, including erythroid progenitor cells, placental villous trophoblasts, and other cells involved in immune regulation. 3. **Adenosine Signaling:** ENT1 is involved in the regulation of adenosine signaling, a key player in immune responses, inflammation, and tissue homeostasis. 4. **Regulation of Immune Responses:** SLC29A1 has been implicated in the regulation of immune responses, including the modulation of T-cell activation, cytokine production, and inflammation. 5. **Blood-Brain Barrier Permeability:** ENT1 has been shown to be involved in the transport of nucleosides across the blood-brain barrier, highlighting its potential role in neurological disorders. **Pathways and Functions:** 1. **Adenosine Signaling Pathway:** ENT1 is involved in the regulation of adenosine signaling, which plays a crucial role in immune responses, inflammation, and tissue homeostasis. 2. **Immune Response Regulation:** SLC29A1 has been implicated in the regulation of immune responses, including the modulation of T-cell activation, cytokine production, and inflammation. 3. **Nucleoside Transport Pathway:** ENT1 facilitates the uptake of nucleosides across cellular membranes, which is essential for the regulation of nucleoside metabolism and signaling. 4. **Blood-Brain Barrier Transport:** ENT1 is involved in the transport of nucleosides across the blood-brain barrier, highlighting its potential role in neurological disorders. **Clinical Significance:** 1. **Immunological Disorders:** Alterations in SLC29A1 expression have been linked to various immunological disorders, including rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease. 2. **Neurological Disorders:** ENT1's role in nucleoside transport across the blood-brain barrier makes it a potential target for the treatment of neurological disorders, such as Alzheimer's disease and Parkinson's disease. 3. **Cancer Therapy:** SLC29A1 has been implicated in cancer therapy, as ENT1's expression is often upregulated in cancer cells, making it a potential target for cancer treatment. 4. **Pregnancy and Fetal Development:** The expression of SLC29A1 in placental villous trophoblasts highlights its potential role in fetal development and pregnancy complications. In conclusion, SLC29A1 is a complex gene involved in nucleoside transport and immune regulation. Its widespread expression and involvement in various cellular processes make it an attractive target for research in immunology, disease pathology, and potential therapeutic applications.

Genular Protein ID: 92181643

Symbol: S29A1_HUMAN

Name: Equilibrative nucleoside transporter 1

UniProtKB Accession Codes:

Q99808 B3KQV7 B3KQY5 Q5T9W9 Q9UJY2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChEBI 11 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 20 DrugCentral 1 EMBL 10 Ensembl 8 ExpressionAtlas 1 GO 41 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIRSF 1 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 3 RefSeq 12 Rhea 11 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8986748

Title: Cloning of a human nucleoside transporter implicated in the cellular uptake of adenosine and chemotherapeutic drugs.

PubMed ID: 8986748

DOI: 10.1038/nm0197-89

PubMed ID: 10755314

Title: Human intestinal es nucleoside transporter: molecular characterization and nucleoside inhibitory profiles.

PubMed ID: 10755314

DOI: 10.1007/s002800050040

PubMed ID: 12384580

Title: Comparative genomic analysis of equilibrative nucleoside transporters suggests conserved protein structure despite limited sequence identity.

PubMed ID: 12384580

DOI: 10.1093/nar/gkf564

PubMed ID: 12527552

Title: Localization of human equilibrative nucleoside transporters, hENT1 and hENT2, in renal epithelial cells.

PubMed ID: 12527552

DOI: 10.1152/ajprenal.00215.2002

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10722669

Title: Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells. Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity for inosine.

PubMed ID: 10722669

DOI: 10.1074/jbc.275.12.8375

PubMed ID: 11584005

Title: Topology of a human equilibrative, nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (hENT1) implicated in the cellular uptake of adenosine and anti-cancer drugs.

PubMed ID: 11584005

DOI: 10.1074/jbc.m107169200

PubMed ID: 11311901

Title: Distinct regional distribution of human equilibrative nucleoside transporter proteins 1 and 2 (hENT1 and hENT2) in the central nervous system.

PubMed ID: 11311901

DOI: 10.1016/s0028-3908(00)00207-0

PubMed ID: 14759222

Title: Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1.

PubMed ID: 14759222

DOI: 10.1042/bj20031880

PubMed ID: 15037197

Title: Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep.

PubMed ID: 15037197

DOI: 10.1016/j.bcp.2003.09.018

PubMed ID: 15501974

Title: The absence of human equilibrative nucleoside transporter 1 is associated with reduced survival in patients with gemcitabine-treated pancreas adenocarcinoma.

PubMed ID: 15501974

DOI: 10.1158/1078-0432.ccr-04-0224

PubMed ID: 17379602

Title: Residues 334 and 338 in transmembrane segment 8 of human equilibrative nucleoside transporter 1 are important determinants of inhibitor sensitivity, protein folding, and catalytic turnover.

PubMed ID: 17379602

DOI: 10.1074/jbc.m701735200

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 21795683

Title: Nucleobase transport by human equilibrative nucleoside transporter 1 (hENT1).

PubMed ID: 21795683

DOI: 10.1074/jbc.m111.236117

PubMed ID: 23219802

Title: Stomatin interacts with GLUT1/SLC2A1, band 3/SLC4A1, and aquaporin-1 in human erythrocyte membrane domains.

PubMed ID: 23219802

DOI: 10.1016/j.bbamem.2012.11.030

PubMed ID: 23639800

Title: Basolateral uptake of nucleosides by Sertoli cells is mediated primarily by equilibrative nucleoside transporter 1.

PubMed ID: 23639800

DOI: 10.1124/jpet.113.203265

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26406980

Title: The Role of Flexible Loops in Folding, Trafficking and Activity of Equilibrative Nucleoside Transporters.

PubMed ID: 26406980

DOI: 10.1371/journal.pone.0136779

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27995448

Title: Functional characterization of human equilibrative nucleoside transporter 1.

PubMed ID: 27995448

DOI: 10.1007/s13238-016-0350-x

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 35790189

Title: Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine.

PubMed ID: 35790189

DOI: 10.1038/s41586-022-05041-0

Sequence Information:

  • Length: 456
  • Mass: 50219
  • Checksum: F18535A95DEBC95D
  • Sequence:
    • MTTSHQPQDR YKAVWLIFFM LGLGTLLPWN FFMTATQYFT NRLDMSQNVS LVTAELSKDA 
QASAAPAAPL PERNSLSAIF NNVMTLCAML PLLLFTYLNS FLHQRIPQSV RILGSLVAIL 
LVFLITAILV KVQLDALPFF VITMIKIVLI NSFGAILQGS LFGLAGLLPA SYTAPIMSGQ 
GLAGFFASVA MICAIASGSE LSESAFGYFI TACAVIILTI ICYLGLPRLE FYRYYQQLKL 
EGPGEQETKL DLISKGEEPR AGKEESGVSV SNSQPTNESH SIKAILKNIS VLAFSVCFIF 
TITIGMFPAV TVEVKSSIAG SSTWERYFIP VSCFLTFNIF DWLGRSLTAV FMWPGKDSRW 
LPSLVLARLV FVPLLLLCNI KPRRYLTVVF EHDAWFIFFM AAFAFSNGYL ASLCMCFGPK 
KVKPAEAETA GAIMAFFLCL GLALGAVFSF LFRAIV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.