Details for: ERG

Gene ID: 2078

Symbol: ERG

Ensembl ID: ENSG00000157554

Description: ETS transcription factor ERG

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 103.5069
    Cell Significance Index: -16.1000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 38.3009
    Cell Significance Index: -15.5600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 31.6586
    Cell Significance Index: -8.0300
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 13.0662
    Cell Significance Index: -16.1100
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 6.3014
    Cell Significance Index: 90.6300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.1307
    Cell Significance Index: -16.3000
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 3.9305
    Cell Significance Index: 40.7100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 3.2587
    Cell Significance Index: 169.7400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 2.3233
    Cell Significance Index: 41.0600
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 1.6795
    Cell Significance Index: 19.0800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 1.5432
    Cell Significance Index: 94.6100
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 1.4184
    Cell Significance Index: 8.5700
  • Cell Name: glomerular capillary endothelial cell (CL1001005)
    Fold Change: 1.2450
    Cell Significance Index: 4.6400
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 1.1641
    Cell Significance Index: 4.0500
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.0051
    Cell Significance Index: 7.9400
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.8752
    Cell Significance Index: 13.3200
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 0.8464
    Cell Significance Index: 5.3000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.7889
    Cell Significance Index: 50.9000
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.6168
    Cell Significance Index: 4.4300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.6135
    Cell Significance Index: 116.7500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4257
    Cell Significance Index: 42.1100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3440
    Cell Significance Index: 9.9100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.2994
    Cell Significance Index: 6.2100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.2928
    Cell Significance Index: 6.2400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.2684
    Cell Significance Index: 7.1800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2651
    Cell Significance Index: 239.3600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2178
    Cell Significance Index: 35.4200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1792
    Cell Significance Index: 19.5000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1745
    Cell Significance Index: 6.1300
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.1405
    Cell Significance Index: 2.9400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1336
    Cell Significance Index: 8.0200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0476
    Cell Significance Index: 29.7100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0363
    Cell Significance Index: 2.5100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0341
    Cell Significance Index: 6.8400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0220
    Cell Significance Index: 4.3800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0040
    Cell Significance Index: 0.7300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.0001
    Cell Significance Index: 0.0700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0013
    Cell Significance Index: -2.4400
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0036
    Cell Significance Index: -2.6700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0050
    Cell Significance Index: -9.2900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0060
    Cell Significance Index: -0.0900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0066
    Cell Significance Index: -10.2200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0082
    Cell Significance Index: -1.0100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0099
    Cell Significance Index: -13.4600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0107
    Cell Significance Index: -6.0100
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0113
    Cell Significance Index: -7.8400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0125
    Cell Significance Index: -0.3200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0144
    Cell Significance Index: -0.3600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0153
    Cell Significance Index: -9.7100
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.0187
    Cell Significance Index: -0.2900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0206
    Cell Significance Index: -15.0900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0214
    Cell Significance Index: -4.5100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0215
    Cell Significance Index: -16.2900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0243
    Cell Significance Index: -8.7000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0276
    Cell Significance Index: -1.2500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0287
    Cell Significance Index: -15.6900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0300
    Cell Significance Index: -0.4300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0305
    Cell Significance Index: -0.6600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0459
    Cell Significance Index: -13.2000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0528
    Cell Significance Index: -9.0100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0538
    Cell Significance Index: -6.9000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0623
    Cell Significance Index: -9.0600
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0844
    Cell Significance Index: -2.3600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.1113
    Cell Significance Index: -12.7100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1126
    Cell Significance Index: -15.4600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1173
    Cell Significance Index: -9.0000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1269
    Cell Significance Index: -16.4000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1416
    Cell Significance Index: -16.5000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1431
    Cell Significance Index: -14.9000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1457
    Cell Significance Index: -16.7000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1510
    Cell Significance Index: -15.4200
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1558
    Cell Significance Index: -2.6700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1715
    Cell Significance Index: -5.6200
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1815
    Cell Significance Index: -7.8900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1870
    Cell Significance Index: -5.9900
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.1893
    Cell Significance Index: -2.6000
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: -0.1904
    Cell Significance Index: -2.3400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1907
    Cell Significance Index: -15.1000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2106
    Cell Significance Index: -14.1600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.2117
    Cell Significance Index: -5.2800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2178
    Cell Significance Index: -16.2300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.2731
    Cell Significance Index: -16.7900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2860
    Cell Significance Index: -10.0200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2974
    Cell Significance Index: -16.6900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3021
    Cell Significance Index: -14.2000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3231
    Cell Significance Index: -14.2900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3363
    Cell Significance Index: -15.6800
  • Cell Name: early promyelocyte (CL0002154)
    Fold Change: -0.3446
    Cell Significance Index: -2.2000
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.3562
    Cell Significance Index: -4.8600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.3774
    Cell Significance Index: -14.2900
  • Cell Name: blood vessel endothelial cell (CL0000071)
    Fold Change: -0.3884
    Cell Significance Index: -4.2200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4027
    Cell Significance Index: -10.3500
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.4057
    Cell Significance Index: -10.8700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.4207
    Cell Significance Index: -7.0400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4397
    Cell Significance Index: -15.2800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.4418
    Cell Significance Index: -14.0700
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.4428
    Cell Significance Index: -9.0100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.4464
    Cell Significance Index: -12.7400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.4748
    Cell Significance Index: -17.4300
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.5124
    Cell Significance Index: -16.2100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ERG is a member of the ETS family of transcription factors, characterized by its ability to bind to specific DNA sequences and regulate gene expression. Its expression is tightly regulated by various signaling pathways, including those involved in cell proliferation, differentiation, and survival. ERG exhibits a high degree of specificity in its DNA binding, allowing it to target specific gene promoters and regulate the expression of target genes. Its ability to interact with other transcription factors and signaling molecules enables it to modulate the transcriptional landscape of target cells. **Pathways and Functions:** ERG plays a crucial role in various cellular processes, including: 1. **Cell Differentiation**: ERG regulates the expression of genes involved in differentiation, including those involved in the development of neural and cardiovascular tissues. 2. **Chromatin Remodeling**: ERG interacts with chromatin remodeling complexes to regulate the accessibility of DNA to transcriptional machinery. 3. **Transcriptional Regulation**: ERG regulates the expression of target genes by binding to specific DNA sequences and recruiting coactivators and corepressors. 4. **Signal Transduction**: ERG interacts with signaling molecules to modulate the transcriptional response to various stimuli. **Clinical Significance:** ERG dysregulation has been implicated in several diseases, including: 1. **Prostate Cancer**: ERG amplification and overexpression are common in prostate cancer, where it contributes to tumorigenesis and progression. 2. **Neurological Disorders**: ERG mutations and dysregulation have been implicated in neurological disorders, including Parkinson's disease, Alzheimer's disease, and amyotrophic lateral sclerosis. 3. **Immune Cell Development**: ERG regulates the development and function of immune cells, including T cells and dendritic cells. In conclusion, ERG is a critical transcription factor that plays a pivotal role in various cellular processes, including cell differentiation, development, and survival. Its dysregulation has been implicated in several diseases, highlighting the importance of ERG in maintaining tissue homeostasis and preventing disease. Further research is needed to fully elucidate the mechanisms by which ERG regulates gene expression and to identify potential therapeutic targets for ERG-related diseases.

Genular Protein ID: 90790890

Symbol: ERG_HUMAN

Name: Transcriptional regulator ERG

UniProtKB Accession Codes:

P11308 B4DTW5 B4E0T4 Q16113 Q6XXX4 Q6XXX5 Q8IXK9

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 4 CDD 1 CORUM 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 ELM 1 EMBL 8 Ensembl 6 EvolutionaryTrace 1 ExpressionAtlas 1 GO 15 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 1 PRINTS 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 RNAct 1 RefSeq 8 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3299708

Title: erg, a human ets-related gene on chromosome 21: alternative splicing, polyadenylation, and translation.

PubMed ID: 3299708

DOI: 10.1126/science.3299708

PubMed ID: 3476934

Title: The erg gene: a human gene related to the ets oncogene.

PubMed ID: 3476934

DOI: 10.1073/pnas.84.17.6131

PubMed ID: 14693372

Title: Detailed mapping of the ERG-ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16.

PubMed ID: 14693372

DOI: 10.1016/j.gene.2003.09.047

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8290279

Title: Differentially spliced erg-3 product functions as a transcriptional activator.

PubMed ID: 8290279

PubMed ID: 8076344

Title: ERG gene is translocated in an Ewing's sarcoma cell line.

PubMed ID: 8076344

DOI: 10.1016/0165-4608(94)90063-9

PubMed ID: 8187069

Title: An RNA-binding protein gene, TLS/FUS, is fused to ERG in human myeloid leukemia with t(16;21) chromosomal translocation.

PubMed ID: 8187069

PubMed ID: 16303180

Title: ELF4 is fused to ERG in a case of acute myeloid leukemia with a t(X;21)(q25-26;q22).

PubMed ID: 16303180

DOI: 10.1016/j.leukres.2005.10.014

PubMed ID: 17289661

Title: Molecular composition of IMP1 ribonucleoprotein granules.

PubMed ID: 17289661

DOI: 10.1074/mcp.m600346-mcp200

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 15351649

Title: Diversity in structure and function of the Ets family PNT domains.

PubMed ID: 15351649

DOI: 10.1016/j.jmb.2004.07.094

PubMed ID: 36928819

Title: Genetic association analysis of 77,539 genomes reveals rare disease etiologies.

PubMed ID: 36928819

DOI: 10.1038/s41591-023-02211-z

Sequence Information:

  • Length: 479
  • Mass: 53838
  • Checksum: A5069C393E409483
  • Sequence:
    • MASTIKEALS VVSEDQSLFE CAYGTPHLAK TEMTASSSSD YGQTSKMSPR VPQQDWLSQP 
PARVTIKMEC NPSQVNGSRN SPDECSVAKG GKMVGSPDTV GMNYGSYMEE KHMPPPNMTT 
NERRVIVPAD PTLWSTDHVR QWLEWAVKEY GLPDVNILLF QNIDGKELCK MTKDDFQRLT 
PSYNADILLS HLHYLRETPL PHLTSDDVDK ALQNSPRLMH ARNTGGAAFI FPNTSVYPEA 
TQRITTRPDL PYEPPRRSAW TGHGHPTPQS KAAQPSPSTV PKTEDQRPQL DPYQILGPTS 
SRLANPGSGQ IQLWQFLLEL LSDSSNSSCI TWEGTNGEFK MTDPDEVARR WGERKSKPNM 
NYDKLSRALR YYYDKNIMTK VHGKRYAYKF DFHGIAQALQ PHPPESSLYK YPSDLPYMGS 
YHAHPQKMNF VAPHPPALPV TSSSFFAAPN PYWNSPTGGI YPNTRLPTSH MPSHLGTYY

Genular Protein ID: 2777376488

Symbol: B5MDW0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B5MDW0

Database IDs:

ARBA 5 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 10 Ensembl 2 GO 5 Gene3D 2 GeneTree 1 HGNC 1 HOGENOM 1 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 6 PeptideAtlas 1 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 455
  • Mass: 51261
  • Checksum: DCC10774F9DA32F7
  • Sequence:
    • MASTIKEALS VVSEDQSLFE CAYGTPHLAK TEMTASSSSD YGQTSKMSPR VPQQDWLSQP 
PARVTIKMEC NPSQVNGSRN SPDECSVAKG GKMVGSPDTV GMNYGSYMEE KHMPPPNMTT 
NERRVIVPAD PTLWSTDHVR QWLEWAVKEY GLPDVNILLF QNIDGKELCK MTKDDFQRLT 
PSYNADILLS HLHYLRETPL PHLTSDDVDK ALQNSPRLMH ARNTDLPYEP PRRSAWTGHG 
HPTPQSKAAQ PSPSTVPKTE DQRPQLDPYQ ILGPTSSRLA NPGSGQIQLW QFLLELLSDS 
SNSSCITWEG TNGEFKMTDP DEVARRWGER KSKPNMNYDK LSRALRYYYD KNIMTKVHGK 
RYAYKFDFHG IAQALQPHPP ESSLYKYPSD LPYMGSYHAH PQKMNFVAPH PPALPVTSSS 
FFAAPNPYWN SPTGGIYPNT RLPTSHMPSH LGTYY

Genular Protein ID: 228784616

Symbol: A0A0C4DG41_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A0C4DG41

Database IDs:

ARBA 5 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 2 GeneTree 1 HGNC 1 InterPro 6 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 6 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SMR 1 SUPFAM 2 VEuPathDB 1

Citations:

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 387
  • Mass: 43974
  • Checksum: 6C19CE3D70C769EA
  • Sequence:
    • MVGSPDTVGM NYGSYMEEKH MPPPNMTTNE RRVIVPADPT LWSTDHVRQW LEWAVKEYGL 
PDVNILLFQN IDGKELCKMT KDDFQRLTPS YNADILLSHL HYLRETPLPH LTSDDVDKAL 
QNSPRLMHAR NTGGAAFIFP NTSVYPEATQ RITTRPDLPY EPPRRSAWTG HGHPTPQSKA 
AQPSPSTVPK TEDQRPQLDP YQILGPTSSR LANPGSGQIQ LWQFLLELLS DSSNSSCITW 
EGTNGEFKMT DPDEVARRWG ERKSKPNMNY DKLSRALRYY YDKNIMTKVH GKRYAYKFDF 
HGIAQALQPH PPESSLYKYP SDLPYMGSYH AHPQKMNFVA PHPPALPVTS SSFFAAPNPY 
WNSPTGGIYP NTRLPTSHMP SHLGTYY

Genular Protein ID: 1543255446

Symbol: B4DN83_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DN83

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 2 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 6 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 2 RuleBase 1 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 486
  • Mass: 54634
  • Checksum: BAEAEB929311D334
  • Sequence:
    • MIQTVPDPAA HIKEALSVVS EDQSLFECAY GTPHLAKTEM TASSSSDYGQ TSKMSPRVPQ 
QDWLSQPPAR VTIKMECNPS QVNGSRNSPD ECSVAKGGKM VGSPDTVGMN YGSYMEEKHM 
PPPNMTTNER RVIVPPDPTL WSTDHVRQWL EWAVKEYGLP DVNILLFQNI DGKELCKMTK 
DDFQRLTPSY NADILLSHLH YLRETPLPHL TSDDVDKALQ NSPRLMHARN TGGAAFIFPN 
TSVYPEATQR ITTRPDLPYE PPRRSAWTGH GHPTPQSKAA QPSPSTVPKT EDQRPQLDPY 
QILGPTSSRL ANPGSGQIQL WQFLLELLSD SSNSSCITWE GTNGEFKMTD PDEVARRWGE 
RKSKPNMNYD KLSRALRYYY DKNIMTKVHG KRYAYKFDFH GIAQALQPHP PESSLYKYPS 
DLPYMGSYHA HPQKMNFVAP HPPALPVTSS SFFAAPNPYW NSPTGGIYPN TRLPTSHMPS 
HLGTYY

Genular Protein ID: 1814007607

Symbol: B4DVX5_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DVX5

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 2 InterPro 6 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 6 PeptideAtlas 1 Pfam 2 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SUPFAM 2

Sequence Information:

  • Length: 362
  • Mass: 41222
  • Checksum: 2858CEE65306887A
  • Sequence:
    • MTTNERRVIV PADPTLWSTD HVRQWLEWAV KEYGLPDVNI LLFQNIDGKE LCKMTKDDFQ 
RLTPSYNADI LLSHLHYLRE TPLPHLTSDD VDKALQNSPR LMHARNTGGA AFIFPNTSVY 
PEATQRITTR PDLPYEPPRR SAWTGHGHPT PQSKAAQPSP STVPKTEDQR PQLDPYQILG 
PTSSRLANPG SGQIQLWQFL LELLSDSSNS SCITWEGTNG EFKMTDPDEV ARRWGERKSK 
PNMNYDKLSR ALRYYYDKNI MTKVHGKRYA YKFDFHGIAQ ALQPHPPESS LYKYPSDLPY 
MGSYHAHPQK MNFVAPHPPA LPVTSSSFFA APNPYWNSPT GGIYPNTRLP TSHMPSHLGT 
YY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.