Details for: FLG

Gene ID: 2312

Symbol: FLG

Ensembl ID: ENSG00000143631

Description: filaggrin

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: epidermal cell (CL0000362)
    Fold Change: 3.8813
    Cell Significance Index: 8.7500
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 1.0500
    Cell Significance Index: 6.9700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 1.0294
    Cell Significance Index: 37.7900
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.8146
    Cell Significance Index: 8.4300
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.6370
    Cell Significance Index: 15.4300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.1290
    Cell Significance Index: 1.7600
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.0977
    Cell Significance Index: 1.6700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0713
    Cell Significance Index: 1.9100
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.0473
    Cell Significance Index: 0.6900
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0472
    Cell Significance Index: 2.3800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0203
    Cell Significance Index: 4.0700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0106
    Cell Significance Index: 16.2700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0095
    Cell Significance Index: 3.4000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0041
    Cell Significance Index: 0.8200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0039
    Cell Significance Index: 0.3000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.0036
    Cell Significance Index: 0.2200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0029
    Cell Significance Index: 5.3000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0026
    Cell Significance Index: 4.9300
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0001
    Cell Significance Index: 0.0200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0032
    Cell Significance Index: -2.0200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0041
    Cell Significance Index: -2.2600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0046
    Cell Significance Index: -6.2500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0050
    Cell Significance Index: -2.2100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0052
    Cell Significance Index: -3.9000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0069
    Cell Significance Index: -3.8700
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0076
    Cell Significance Index: -1.1000
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.0084
    Cell Significance Index: -0.1300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0096
    Cell Significance Index: -4.3400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0176
    Cell Significance Index: -3.1800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0226
    Cell Significance Index: -3.8600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0236
    Cell Significance Index: -1.5900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0246
    Cell Significance Index: -1.0900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0248
    Cell Significance Index: -0.6900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0265
    Cell Significance Index: -3.6400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0286
    Cell Significance Index: -2.9200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0286
    Cell Significance Index: -1.6100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0290
    Cell Significance Index: -3.5600
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0312
    Cell Significance Index: -3.6400
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0324
    Cell Significance Index: -3.7100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0363
    Cell Significance Index: -1.3800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0375
    Cell Significance Index: -3.9000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0397
    Cell Significance Index: -2.5000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0422
    Cell Significance Index: -1.7300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0443
    Cell Significance Index: -1.1400
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0450
    Cell Significance Index: -1.1300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0525
    Cell Significance Index: -1.1500
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0595
    Cell Significance Index: -1.5200
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0678
    Cell Significance Index: -1.6900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0709
    Cell Significance Index: -1.7000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0755
    Cell Significance Index: -3.5500
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.0814
    Cell Significance Index: -1.1400
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: -0.0976
    Cell Significance Index: -1.1300
  • Cell Name: monocyte (CL0000576)
    Fold Change: -0.1025
    Cell Significance Index: -1.1800
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.1079
    Cell Significance Index: -1.4800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1105
    Cell Significance Index: -3.8700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1109
    Cell Significance Index: -1.9000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1226
    Cell Significance Index: -3.6100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1230
    Cell Significance Index: -3.5100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1240
    Cell Significance Index: -4.0600
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.1312
    Cell Significance Index: -2.6700
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.1321
    Cell Significance Index: -2.1400
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: -0.1337
    Cell Significance Index: -1.2800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1377
    Cell Significance Index: -4.3900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1386
    Cell Significance Index: -7.2000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1397
    Cell Significance Index: -3.7300
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1422
    Cell Significance Index: -2.1000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1434
    Cell Significance Index: -3.7700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1446
    Cell Significance Index: -1.6400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1447
    Cell Significance Index: -1.7300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1448
    Cell Significance Index: -6.7500
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: -0.1533
    Cell Significance Index: -1.6600
  • Cell Name: T cell (CL0000084)
    Fold Change: -0.1635
    Cell Significance Index: -1.9300
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.1644
    Cell Significance Index: -2.0700
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1652
    Cell Significance Index: -2.0600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1658
    Cell Significance Index: -2.3800
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: -0.1666
    Cell Significance Index: -2.3400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1679
    Cell Significance Index: -3.3700
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.1706
    Cell Significance Index: -2.8700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1743
    Cell Significance Index: -3.7000
  • Cell Name: professional antigen presenting cell (CL0000145)
    Fold Change: -0.1748
    Cell Significance Index: -1.5800
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: -0.1762
    Cell Significance Index: -1.9600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1774
    Cell Significance Index: -4.4300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1800
    Cell Significance Index: -3.8900
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.1816
    Cell Significance Index: -3.5500
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.1834
    Cell Significance Index: -3.5800
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.1868
    Cell Significance Index: -3.2300
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1878
    Cell Significance Index: -3.1900
  • Cell Name: neutrophil (CL0000775)
    Fold Change: -0.1905
    Cell Significance Index: -2.3800
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.1932
    Cell Significance Index: -2.5000
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1953
    Cell Significance Index: -3.2900
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.1974
    Cell Significance Index: -4.1200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1982
    Cell Significance Index: -3.9200
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.2024
    Cell Significance Index: -3.7400
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.2042
    Cell Significance Index: -4.0200
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: -0.2043
    Cell Significance Index: -2.5900
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.2065
    Cell Significance Index: -6.5300
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.2121
    Cell Significance Index: -4.2300
  • Cell Name: ionocyte (CL0005006)
    Fold Change: -0.2152
    Cell Significance Index: -2.2500
  • Cell Name: basal cell (CL0000646)
    Fold Change: -0.2168
    Cell Significance Index: -2.5800
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.2271
    Cell Significance Index: -3.1500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** Filaggrin is a multifunctional protein that exhibits several key characteristics, including: 1. **Calcium ion binding**: FLG binds to calcium ions, which is essential for the protein's function in the skin barrier. 2. **Protein binding**: FLG interacts with various proteins, including keratin 14 and keratin 17, to regulate the structure and function of the skin's extracellular matrix. 3. **Peptide cross-linking**: FLG facilitates the cross-linking of peptides, which is critical for the formation of the cornified envelope. 4. **Structural constituent of skin epidermis**: FLG is a structural component of the skin's epidermis, where it contributes to the maintenance of the skin barrier. **Pathways and Functions** FLG is involved in several key pathways, including: 1. **Establishment of skin barrier**: FLG plays a critical role in the establishment and maintenance of the skin barrier, where it regulates the structure and function of the skin's extracellular matrix. 2. **Formation of the cornified envelope**: FLG is essential for the formation of the cornified envelope, a critical component of the skin's outermost layer. 3. **Keratinization**: FLG regulates the process of keratinization, which is the process by which keratinocytes undergo differentiation to form the skin's outermost layer. 4. **Immune homeostasis**: FLG is also involved in regulating immune responses, where it interacts with various immune cells, including mast cells and goblet cells. **Clinical Significance** Dysregulation of FLG has been implicated in several skin disorders, including: 1. **Atopic dermatitis**: FLG mutations have been associated with atopic dermatitis, a chronic skin condition characterized by dry, itchy skin. 2. **Eczema**: FLG mutations have also been linked to eczema, a condition characterized by dry, scaly skin. 3. **Psoriasis**: FLG mutations have been associated with psoriasis, a condition characterized by thick, scaly skin. In conclusion, FLG is a critical protein that plays a vital role in maintaining the integrity of the skin barrier and regulating immune responses. Dysregulation of FLG has been implicated in several skin disorders, highlighting the importance of this protein in maintaining skin health. Further research is needed to fully understand the mechanisms by which FLG regulates skin barrier function and immune homeostasis.

Genular Protein ID: 2686266898

Symbol: FILA_HUMAN

Name: Filaggrin

UniProtKB Accession Codes:

P20930 Q01720 Q5T583 Q9UC71

Database IDs:

AGR 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEBI 5 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 1 EvolutionaryTrace 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 3 PRIDE 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 1429717

Title: Characterization of the human epidermal profilaggrin gene. Genomic organization and identification of an S-100-like calcium binding domain at the amino terminus.

PubMed ID: 1429717

DOI: 10.1016/s0021-9258(18)35905-2

PubMed ID: 2740331

Title: Characterization of a cDNA clone encoding human filaggrin and localization of the gene to chromosome region 1q21.

PubMed ID: 2740331

DOI: 10.1073/pnas.86.13.4848

PubMed ID: 7612609

Title: Identification of the amino terminus of human filaggrin using differential LC/MS techniques: implications for profilaggrin processing.

PubMed ID: 7612609

DOI: 10.1021/bi00027a018

PubMed ID: 25946035

Title: Human basal tear peptidome characterization by CID, HCD, and ETD followed by in silico and in vitro analyses for antimicrobial peptide identification.

PubMed ID: 25946035

DOI: 10.1021/acs.jproteome.5b00179

PubMed ID: 8780679

Title: Preferential deimination of keratin K1 and filaggrin during the terminal differentiation of human epidermis.

PubMed ID: 8780679

DOI: 10.1006/bbrc.1996.1240

PubMed ID: 16815158

Title: Loss-of-function variations within the filaggrin gene predispose for atopic dermatitis with allergic sensitizations.

PubMed ID: 16815158

DOI: 10.1016/j.jaci.2006.05.004

PubMed ID: 17030239

Title: Filaggrin loss-of-function mutations predispose to phenotypes involved in the atopic march.

PubMed ID: 17030239

DOI: 10.1016/j.jaci.2006.07.026

PubMed ID: 16444271

Title: Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris.

PubMed ID: 16444271

DOI: 10.1038/ng1743

PubMed ID: 16550169

Title: Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis.

PubMed ID: 16550169

DOI: 10.1038/ng1767

PubMed ID: 17291859

Title: Unique mutations in the filaggrin gene in Japanese patients with ichthyosis vulgaris and atopic dermatitis.

PubMed ID: 17291859

DOI: 10.1016/j.jaci.2006.12.646

PubMed ID: 19384417

Title: Molecular identification and expression analysis of filaggrin-2, a member of the S100 fused-type protein family.

PubMed ID: 19384417

DOI: 10.1371/journal.pone.0005227

PubMed ID: 21531719

Title: Deimination of human filaggrin-2 promotes its proteolysis by calpain 1.

PubMed ID: 21531719

DOI: 10.1074/jbc.m110.197400

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 4061
  • Mass: 435170
  • Checksum: 3F4B1181F04AD9C0
  • Sequence:
    • MSTLLENIFA IINLFKQYSK KDKNTDTLSK KELKELLEKE FRQILKNPDD PDMVDVFMDH 
LDIDHNKKID FTEFLLMVFK LAQAYYESTR KENLPISGHK HRKHSHHDKH EDNKQEENKE 
NRKRPSSLER RNNRKGNKGR SKSPRETGGK RHESSSEKKE RKGYSPTHRE EEYGKNHHNS 
SKKEKNKTEN TRLGDNRKRL SERLEEKEDN EEGVYDYENT GRMTQKWIQS GHIATYYTIQ 
DEAYDTTDSL LEENKIYERS RSSDGKSSSQ VNRSRHENTS QVPLQESRTR KRRGSRVSQD 
RDSEGHSEDS ERHSGSASRN HHGSAWEQSR DGSRHPRSHD EDRASHGHSA DSSRQSGTRH 
AETSSRGQTA SSHEQARSSP GERHGSGHQQ SADSSRHSAT GRGQASSAVS DRGHRGSSGS 
QASDSEGHSE NSDTQSVSGH GKAGLRQQSH QESTRGRSGE RSGRSGSSLY QVSTHEQPDS 
AHGRTGTSTG GRQGSHHEQA RDSSRHSASQ EGQDTIRGHP GSSRGGRQGS HHEQSVNRSG 
HSGSHHSHTT SQGRSDASHG QSGSRSASRQ TRNEEQSGDG TRHSGSRHHE ASSQADSSRH 
SQVGQGQSSG PRTSRNQGSS VSQDSDSQGH SEDSERWSGS ASRNHHGSAQ EQSRDGSRHP 
RSHHEDRAGH GHSADSSRKS GTRHTQNSSS GQAASSHEQA RSSAGERHGS RHQLQSADSS 
RHSGTGHGQA SSAVRDSGHR GSSGSQATDS EGHSEDSDTQ SVSGHGQAGH HQQSHQESAR 
DRSGERSRRS GSFLYQVSTH KQSESSHGWT GPSTGVRQGS HHEQARDNSR HSASQDGQDT 
IRGHPGSSRR GRQGSHHEQS VDRSGHSGSH HSHTTSQGRS DASRGQSGSR SASRTTRNEE 
QSRDGSRHSG SRHHEASSHA DISRHSQAGQ GQSEGSRTSR RQGSSVSQDS DSEGHSEDSE 
RWSGSASRNH RGSAQEQSRH GSRHPRSHHE DRAGHGHSAD SSRQSGTPHA ETSSGGQAAS 
SHEQARSSPG ERHGSRHQQS ADSSRHSGIP RRQASSAVRD SGHWGSSGSQ ASDSEGHSEE 
SDTQSVSGHG QDGPHQQSHQ ESARDWSGGR SGRSGSFIYQ VSTHEQSESA HGRTRTSTGR 
RQGSHHEQAR DSSRHSASQE GQDTIRAHPG SRRGGRQGSH HEQSVDRSGH SGSHHSHTTS 
QGRSDASHGQ SGSRSASRQT RKDKQSGDGS RHSGSRHHEA ASWADSSRHS QVGQEQSSGS 
RTSRHQGSSV SQDSDSERHS DDSERLSGSA SRNHHGSSRE QSRDGSRHPG FHQEDRASHG 
HSADSSRQSG THHTESSSHG QAVSSHEQAR SSPGERHGSR HQQSADSSRH SGIGHRQASS 
AVRDSGHRGS SGSQVTNSEG HSEDSDTQSV SAHGQAGPHQ QSHKESARGQ SGESSGRSRS 
FLYQVSSHEQ SESTHGQTAP STGGRQGSRH EQARNSSRHS ASQDGQDTIR GHPGSSRGGR 
QGSYHEQSVD RSGHSGYHHS HTTPQGRSDA SHGQSGPRSA SRQTRNEEQS GDGSRHSGSR 
HHEPSTRAGS SRHSQVGQGE SAGSKTSRRQ GSSVSQDRDS EGHSEDSERR SESASRNHYG 
SAREQSRHGS RNPRSHQEDR ASHGHSAESS RQSGTRHAET SSGGQAASSQ EQARSSPGER 
HGSRHQQSAD SSTDSGTGRR QDSSVVGDSG NRGSSGSQAS DSEGHSEESD TQSVSAHGQA 
GPHQQSHQES TRGQSGERSG RSGSFLYQVS THEQSESAHG RTGPSTGGRQ RSRHEQARDS 
SRHSASQEGQ DTIRGHPGSS RGGRQGSHYE QSVDSSGHSG SHHSHTTSQE RSDVSRGQSG 
SRSVSRQTRN EKQSGDGSRH SGSRHHEASS RADSSRHSQV GQGQSSGPRT SRNQGSSVSQ 
DSDSQGHSED SERWSGSASR NHLGSAWEQS RDGSRHPGSH HEDRAGHGHS ADSSRQSGTR 
HTESSSRGQA ASSHEQARSS AGERHGSHHQ LQSADSSRHS GIGHGQASSA VRDSGHRGYS 
GSQASDSEGH SEDSDTQSVS AQGKAGPHQQ SHKESARGQS GESSGRSGSF LYQVSTHEQS 
ESTHGQSAPS TGGRQGSHYD QAQDSSRHSA SQEGQDTIRG HPGPSRGGRQ GSHQEQSVDR 
SGHSGSHHSH TTSQGRSDAS RGQSGSRSAS RKTYDKEQSG DGSRHSGSHH HEASSWADSS 
RHSLVGQGQS SGPRTSRPRG SSVSQDSDSE GHSEDSERRS GSASRNHHGS AQEQSRDGSR 
HPRSHHEDRA GHGHSAESSR QSGTHHAENS SGGQAASSHE QARSSAGERH GSHHQQSADS 
SRHSGIGHGQ ASSAVRDSGH RGSSGSQASD SEGHSEDSDT QSVSAHGQAG PHQQSHQEST 
RGRSAGRSGR SGSFLYQVST HEQSESAHGR TGTSTGGRQG SHHKQARDSS RHSTSQEGQD 
TIHGHPGSSS GGRQGSHYEQ LVDRSGHSGS HHSHTTSQGR SDASHGHSGS RSASRQTRND 
EQSGDGSRHS GSRHHEASSR ADSSGHSQVG QGQSEGPRTS RNWGSSFSQD SDSQGHSEDS 
ERWSGSASRN HHGSAQEQLR DGSRHPRSHQ EDRAGHGHSA DSSRQSGTRH TQTSSGGQAA 
SSHEQARSSA GERHGSHHQQ SADSSRHSGI GHGQASSAVR DSGHRGYSGS QASDNEGHSE 
DSDTQSVSAH GQAGSHQQSH QESARGRSGE TSGHSGSFLY QVSTHEQSES SHGWTGPSTR 
GRQGSRHEQA QDSSRHSASQ DGQDTIRGHP GSSRGGRQGY HHEHSVDSSG HSGSHHSHTT 
SQGRSDASRG QSGSRSASRT TRNEEQSGDG SRHSGSRHHE ASTHADISRH SQAVQGQSEG 
SRRSRRQGSS VSQDSDSEGH SEDSERWSGS ASRNHHGSAQ EQLRDGSRHP RSHQEDRAGH 
GHSADSSRQS GTRHTQTSSG GQAASSHEQA RSSAGERHGS HHQQSADSSR HSGIGHGQAS 
SAVRDSGHRG YSGSQASDNE GHSEDSDTQS VSAHGQAGSH QQSHQESARG RSGETSGHSG 
SFLYQVSTHE QSESSHGWTG PSTRGRQGSR HEQAQDSSRH SASQYGQDTI RGHPGSSRGG 
RQGYHHEHSV DSSGHSGSHH SHTTSQGRSD ASRGQSGSRS ASRTTRNEEQ SGDSSRHSVS 
RHHEASTHAD ISRHSQAVQG QSEGSRRSRR QGSSVSQDSD SEGHSEDSER WSGSASRNHR 
GSVQEQSRHG SRHPRSHHED RAGHGHSADR SRQSGTRHAE TSSGGQAASS HEQARSSPGE 
RHGSRHQQSA DSSRHSGIPR GQASSAVRDS RHWGSSGSQA SDSEGHSEES DTQSVSGHGQ 
AGPHQQSHQE SARDRSGGRS GRSGSFLYQV STHEQSESAH GRTRTSTGRR QGSHHEQARD 
SSRHSASQEG QDTIRGHPGS SRRGRQGSHY EQSVDRSGHS GSHHSHTTSQ GRSDASRGQS 
GSRSASRQTR NDEQSGDGSR HSWSHHHEAS TQADSSRHSQ SGQGQSAGPR TSRNQGSSVS 
QDSDSQGHSE DSERWSGSAS RNHRGSAQEQ SRDGSRHPTS HHEDRAGHGH SAESSRQSGT 
HHAENSSGGQ AASSHEQARS SAGERHGSHH QQSADSSRHS GIGHGQASSA VRDSGHRGSS 
GSQASDSEGH SEDSDTQSVS AHGQAGPHQQ SHQESTRGRS AGRSGRSGSF LYQVSTHEQS 
ESAHGRAGPS TGGRQGSRHE QARDSSRHSA SQEGQDTIRG HPGSRRGGRQ GSYHEQSVDR 
SGHSGSHHSH TTSQGRSDAS HGQSGSRSAS RETRNEEQSG DGSRHSGSRH HEASTQADSS 
RHSQSGQGES AGSRRSRRQG SSVSQDSDSE AYPEDSERRS ESASRNHHGS SREQSRDGSR 
HPGSSHRDTA SHVQSSPVQS DSSTAKEHGH FSSLSQDSAY HSGIQSRGSP HSSSSYHYQS 
EGTERQKGQS GLVWRHGSYG SADYDYGESG FRHSQHGSVS YNSNPVVFKE RSDICKASAF 
GKDHPRYYAT YINKDPGLCG HSSDISKQLG FSQSQRYYYY E

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.