Details for: GLI3

Gene ID: 2737

Symbol: GLI3

Ensembl ID: ENSG00000106571

Description: GLI family zinc finger 3

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 3.99
    Marker Score: 3280
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 2.85
    Marker Score: 60903
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 2.78
    Marker Score: 3462
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 2.74
    Marker Score: 1599
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.31
    Marker Score: 9663
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.82
    Marker Score: 1577
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 1.7
    Marker Score: 1116
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 1.68
    Marker Score: 490
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 1.62
    Marker Score: 552
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 1.59
    Marker Score: 892
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.59
    Marker Score: 1156
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 1.53
    Marker Score: 850
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.52
    Marker Score: 3092
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 1.39
    Marker Score: 2678
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.37
    Marker Score: 679
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.36
    Marker Score: 860
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.35
    Marker Score: 1553
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.27
    Marker Score: 1434
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 1.26
    Marker Score: 831
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.24
    Marker Score: 389
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.24
    Marker Score: 19390.5
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.18
    Marker Score: 2777
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.15
    Marker Score: 1023
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.14
    Marker Score: 4785
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.08
    Marker Score: 281
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.06
    Marker Score: 637
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 1.06
    Marker Score: 6367
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 1.04
    Marker Score: 251762
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71780
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48005
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30405
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 0.98
    Marker Score: 4065
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.97
    Marker Score: 501
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.96
    Marker Score: 455
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.96
    Marker Score: 2602
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2410
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.94
    Marker Score: 2212
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.94
    Marker Score: 6111
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 0.94
    Marker Score: 704.5
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.94
    Marker Score: 388
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.94
    Marker Score: 238
  • Cell Name: neural progenitor cell (CL0011020)
    Fold Change: 0.93
    Marker Score: 3595
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.93
    Marker Score: 5282
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 0.93
    Marker Score: 12208
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.92
    Marker Score: 368
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2733
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 322
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5275
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.86
    Marker Score: 199
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 0.85
    Marker Score: 589
  • Cell Name: Unknown (CL0002371)
    Fold Change: 0.83
    Marker Score: 884
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.83
    Marker Score: 396
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.81
    Marker Score: 13030
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.79
    Marker Score: 607
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: 0.77
    Marker Score: 2867
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.77
    Marker Score: 1251
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.76
    Marker Score: 7681
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.76
    Marker Score: 819
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.76
    Marker Score: 692
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.76
    Marker Score: 335
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 391
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 0.75
    Marker Score: 718
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.75
    Marker Score: 213
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 0.75
    Marker Score: 798
  • Cell Name: neural cell (CL0002319)
    Fold Change: 0.74
    Marker Score: 358
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.73
    Marker Score: 808
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.72
    Marker Score: 871.5
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.71
    Marker Score: 455
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.7
    Marker Score: 179
  • Cell Name: fat cell (CL0000136)
    Fold Change: 0.69
    Marker Score: 387
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.69
    Marker Score: 254
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.68
    Marker Score: 822
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.67
    Marker Score: 215
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 0.66
    Marker Score: 2741.5
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.66
    Marker Score: 24376.5
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 0.66
    Marker Score: 621.5
  • Cell Name: skeletal muscle satellite stem cell (CL0008011)
    Fold Change: 0.66
    Marker Score: 703
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.66
    Marker Score: 392.5
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 0.65
    Marker Score: 1007
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 0.65
    Marker Score: 436
  • Cell Name: Schwann cell (CL0002573)
    Fold Change: 0.65
    Marker Score: 224
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 0.64
    Marker Score: 158
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.63
    Marker Score: 668
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 0.63
    Marker Score: 613
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.63
    Marker Score: 812
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.62
    Marker Score: 537
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 0.61
    Marker Score: 4547
  • Cell Name: mesothelial cell (CL0000077)
    Fold Change: 0.61
    Marker Score: 244
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.6
    Marker Score: 2345
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.59
    Marker Score: 221
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.58
    Marker Score: 252
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.58
    Marker Score: 10220
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.57
    Marker Score: 208
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.57
    Marker Score: 263
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.57
    Marker Score: 148
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 0.57
    Marker Score: 784
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 0.56
    Marker Score: 1478.5
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.56
    Marker Score: 148
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 0.56
    Marker Score: 987
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.56
    Marker Score: 443

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Other Information

**Key characteristics**: * GLI3 is a zinc finger protein that is highly expressed in proliferating cells. * It is a key regulator of epithelial cell differentiation. * It is also involved in the regulation of cell growth and survival. **Pathways and functions**: * GLI3 binds to DNA sequences that are involved in the regulation of epithelial cell differentiation. * It is a key regulator of the expression of genes that are involved in epithelial cell differentiation, such as those encoding collagen, proteoglycans, and other extracellular matrix proteins. * GLI3 also binds to DNA sequences that are involved in the regulation of cell growth and survival. * It is involved in the regulation of cell cycle progression, apoptosis, and angiogenesis. **Clinical significance**: * Mutations in the GLI3 gene have been linked to a number of human diseases, including cancer and developmental disorders. * GLI3 inhibitors are being investigated as a potential therapy for these diseases. **Additional information**: * GLI3 is a member of the GLI family of zinc finger proteins. * GLI proteins are known to be transcription factors that regulate the expression of a variety of genes. * They play an important role in cell differentiation, proliferation, and survival.

Genular Protein ID: 3411184940

Symbol: GLI3_HUMAN

Name: Transcriptional activator GLI3

UniProtKB Accession Codes:

P10071 A4D1W1 O75219 Q17RW4 Q75MT0 Q75MU9 Q9UDT5 Q9UJ39

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 ELM 1 EMBL 10 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 94 Gene3D 1 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 10 MINT 1 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 7 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 5 RefSeq 1 SAM 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2118997

Title: GLI3 encodes a 190-kilodalton protein with multiple regions of GLI similarity.

PubMed ID: 2118997

DOI: 10.1128/mcb.10.10.5408-5415.1990

PubMed ID: 10441342

Title: Point mutations throughout the GLI3 gene cause Greig cephalopolysyndactylysyndrome.

PubMed ID: 10441342

DOI: 10.1093/hmg/8.9.1769

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12690205

Title: Human chromosome 7: DNA sequence and biology.

PubMed ID: 12690205

DOI: 10.1126/science.1083423

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2850480

Title: The GLI-Kruppel family of human genes.

PubMed ID: 2850480

DOI: 10.1128/mcb.8.8.3104-3113.1988

PubMed ID: 10693759

Title: Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb.

PubMed ID: 10693759

DOI: 10.1016/s0092-8674(00)80678-9

PubMed ID: 11238441

Title: Physical and functional interactions between Zic and Gli proteins.

PubMed ID: 11238441

DOI: 10.1074/jbc.c000773200

PubMed ID: 16705181

Title: Multisite protein kinase A and glycogen synthase kinase 3beta phosphorylation leads to Gli3 ubiquitination by SCFbetaTrCP.

PubMed ID: 16705181

DOI: 10.1128/mcb.02183-05

PubMed ID: 16371461

Title: Evidence for the direct involvement of {beta}TrCP in Gli3 protein processing.

PubMed ID: 16371461

DOI: 10.1073/pnas.0509927103

PubMed ID: 18455992

Title: Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling.

PubMed ID: 18455992

DOI: 10.1016/j.cell.2008.02.047

PubMed ID: 17764085

Title: Characterization of the interactions of human ZIC3 mutants with GLI3.

PubMed ID: 17764085

DOI: 10.1002/humu.20606

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19592253

Title: The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development.

PubMed ID: 19592253

DOI: 10.1016/j.cub.2009.06.046

PubMed ID: 19389374

Title: Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3.

PubMed ID: 19389374

DOI: 10.1016/j.ydbio.2009.01.012

PubMed ID: 19878745

Title: Identification of a novel serine/threonine kinase ULK3 as a positive regulator of Hedgehog pathway.

PubMed ID: 19878745

DOI: 10.1016/j.yexcr.2009.10.018

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23955340

Title: Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis.

PubMed ID: 23955340

DOI: 10.1074/jbc.m113.492066

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 24311597

Title: Structural basis of SUFU-GLI interaction in human Hedgehog signalling regulation.

PubMed ID: 24311597

DOI: 10.1107/s0907444913028473

PubMed ID: 9302279

Title: Point mutations in human GLI3 cause Greig syndrome.

PubMed ID: 9302279

DOI: 10.1093/hmg/6.11.1979

PubMed ID: 10441570

Title: The phenotypic spectrum of GLI3 morphopathies includes autosomal dominant preaxial polydactyly type-IV and postaxial polydactyly type-A/B; no phenotype prediction from the position of GLI3 mutations.

PubMed ID: 10441570

DOI: 10.1086/302557

PubMed ID: 12414818

Title: De novo GLI3 mutation in acrocallosal syndrome: broadening the phenotypic spectrum of GLI3 defects and overlap with murine models.

PubMed ID: 12414818

DOI: 10.1136/jmg.39.11.804

PubMed ID: 12794692

Title: Variable phenotype in Greig cephalopolysyndactyly syndrome: clinical and radiological findings in 4 independent families and 3 sporadic cases with identified GLI3 mutations.

PubMed ID: 12794692

DOI: 10.1002/ajmg.a.20018

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

PubMed ID: 28965847

Title: Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects.

PubMed ID: 28965847

DOI: 10.1016/j.ajhg.2017.08.017

PubMed ID: 29263200

Title: WDR11-mediated Hedgehog signalling defects underlie a new ciliopathy related to Kallmann syndrome.

PubMed ID: 29263200

DOI: 10.15252/embr.201744632

Sequence Information:

  • Length: 1580
  • Mass: 169863
  • Checksum: 423B7495FCE3C37C
  • Sequence:
    • MEAQSHSSTT TEKKKVENSI VKCSTRTDVS EKAVASSTTS NEDESPGQTY HRERRNAITM 
QPQNVQGLSK VSEEPSTSSD ERASLIKKEI HGSLPHVAEP SVPYRGTVFA MDPRNGYMEP 
HYHPPHLFPA FHPPVPIDAR HHEGRYHYDP SPIPPLHMTS ALSSSPTYPD LPFIRISPHR 
NPTAASESPF SPPHPYINPY MDYIRSLHSS PSLSMISATR GLSPTDAPHA GVSPAEYYHQ 
MALLTGQRSP YADIIPSAAT AGTGAIHMEY LHAMDSTRFS SPRLSARPSR KRTLSISPLS 
DHSFDLQTMI RTSPNSLVTI LNNSRSSSSA SGSYGHLSAS AISPALSFTY SSAPVSLHMH 
QQILSRQQSL GSAFGHSPPL IHPAPTFPTQ RPIPGIPTVL NPVQVSSGPS ESSQNKPTSE 
SAVSSTGDPM HNKRSKIKPD EDLPSPGARG QQEQPEGTTL VKEEGDKDES KQEPEVIYET 
NCHWEGCARE FDTQEQLVHH INNDHIHGEK KEFVCRWLDC SREQKPFKAQ YMLVVHMRRH 
TGEKPHKCTF EGCTKAYSRL ENLKTHLRSH TGEKPYVCEH EGCNKAFSNA SDRAKHQNRT 
HSNEKPYVCK IPGCTKRYTD PSSLRKHVKT VHGPEAHVTK KQRGDIHPRP PPPRDSGSHS 
QSRSPGRPTQ GALGEQQDLS NTTSKREECL QVKTVKAEKP MTSQPSPGGQ SSCSSQQSPI 
SNYSNSGLEL PLTDGGSIGD LSAIDETPIM DSTISTATTA LALQARRNPA GTKWMEHVKL 
ERLKQVNGMF PRLNPILPPK APAVSPLIGN GTQSNNTCSL GGPMTLLPGR SDLSGVDVTM 
LNMLNRRDSS ASTISSAYLS SRRSSGISPC FSSRRSSEAS QAEGRPQNVS VADSYDPIST 
DASRRSSEAS QSDGLPSLLS LTPAQQYRLK AKYAAATGGP PPTPLPNMER MSLKTRLALL 
GDALEPGVAL PPVHAPRRCS DGGAHGYGRR HLQPHDAPGH GVRRASDPVR TGSEGLALPR 
VPRFSSLSSC NPPAMATSAE KRSLVLQNYT RPEGGQSRNF HSSPCPPSIT ENVTLESLTM 
DADANLNDED FLPDDVVQYL NSQNQAGYEQ HFPSALPDDS KVPHGPGDFD APGLPDSHAG 
QQFHALEQPC PEGSKTDLPI QWNEVSSGSA DLSSSKLKCG PRPAVPQTRA FGFCNGMVVH 
PQNPLRSGPA GGYQTLGENS NPYGGPEHLM LHNSPGSGTS GNAFHEQPCK APQYGNCLNR 
QPVAPGALDG ACGAGIQASK LKSTPMQGSG GQLNFGLPVA PNESAGSMVN GMQNQDPVGQ 
GYLAHQLLGD SMQHPGAGRP GQQMLGQISA TSHINIYQGP ESCLPGAHGM GSQPSSLAVV 
RGYQPCASFG GSRRQAMPRD SLALQSGQLS DTSQTCRVNG IKMEMKGQPH PLCSNLQNYS 
GQFYDQTVGF SQQDTKAGSF SISDASCLLQ GTSAKNSELL SPGANQVTST VDSLDSHDLE 
GVQIDFDAII DDGDHSSLMS GALSPSIIQN LSHSSSRLTT PRASLPFPAL SMSTTNMAIG 
DMSSLLTSLA EESKFLAVMQ

Genular Protein ID: 3498213119

Symbol: A0A2R8YGX0_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A2R8YGX0

Database IDs:

ARBA 13 Antibodypedia 1 Bgee 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 1 GeneTree 1 HGNC 1 InterPro 3 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 Proteomes 2 RefSeq 1 SAM 1 SMART 1 SMR 1 SUPFAM 1 VEuPathDB 1

Citations:

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

Sequence Information:

  • Length: 1521
  • Mass: 163351
  • Checksum: EC027BE010E051C7
  • Sequence:
    • MQPQNVQGLS KVSEEPSTSS DERASLIKKE IHGSLPHVAE PSVPYRGTVF AMDPRNGYME 
PHYHPPHLFP AFHPPVPIDA RHHEGRYHYD PSPIPPLHMT SALSSSPTYP DLPFIRISPH 
RNPTAASESP FSPPHPYINP YMDYIRSLHS SPSLSMISAT RGLSPTDAPH AGVSPAEYYH 
QMALLTGQRS PYADIIPSAA TAGTGAIHME YLHAMDSTRF SSPRLSARPS RKRTLSISPL 
SDHSFDLQTM IRTSPNSLVT ILNNSRSSSS ASGSYGHLSA SAISPALSFT YSSAPVSLHM 
HQQILSRQQS LGSAFGHSPP LIHPAPTFPT QRPIPGIPTV LNPVQVSSGP SESSQNKPTS 
ESAVSSTGDP MHNKRSKIKP DEDLPSPGAR GQQEQPEGTT LVKEEGDKDE SKQEPEVIYE 
TNCHWEGCAR EFDTQEQLVH HINNDHIHGE KKEFVCRWLD CSREQKPFKA QYMLVVHMRR 
HTGEKPHKCT FEGCTKAYSR LENLKTHLRS HTGEKPYVCE HEGCNKAFSN ASDRAKHQNR 
THSNEKPYVC KIPGCTKRYT DPSSLRKHVK TVHGPEAHVT KKQRGDIHPR PPPPRDSGSH 
SQSRSPGRPT QGALGEQQDL SNTTSKREEC LQVKTVKAEK PMTSQPSPGG QSSCSSQQSP 
ISNYSNSGLE LPLTDGGSIG DLSAIDETPI MDSTISTATT ALALQARRNP AGTKWMEHVK 
LERLKQVNGM FPRLNPILPP KAPAVSPLIG NGTQSNNTCS LGGPMTLLPG RSDLSGVDVT 
MLNMLNRRDS SASTISSAYL SSRRSSGISP CFSSRRSSEA SQAEGRPQNV SVADSYDPIS 
TDASRRSSEA SQSDGLPSLL SLTPAQQYRL KAKYAAATGG PPPTPLPNME RMSLKTRLAL 
LGDALEPGVA LPPVHAPRRC SDGGAHGYGR RHLQPHDAPG HGVRRASDPV RTGSEGLALP 
RVPRFSSLSS CNPPAMATSA EKRSLVLQNY TRPEGGQSRN FHSSPCPPSI TENVTLESLT 
MDADANLNDE DFLPDDVVQY LNSQNQAGYE QHFPSALPDD SKVPHGPGDF DAPGLPDSHA 
GQQFHALEQP CPEGSKTDLP IQWNEVSSGS ADLSSSKLKC GPRPAVPQTR AFGFCNGMVV 
HPQNPLRSGP AGGYQTLGEN SNPYGGPEHL MLHNSPGSGT SGNAFHEQPC KAPQYGNCLN 
RQPVAPGALD GACGAGIQAS KLKSTPMQGS GGQLNFGLPV APNESAGSMV NGMQNQDPVG 
QGYLAHQLLG DSMQHPGAGR PGQQMLGQIS ATSHINIYQG PESCLPGAHG MGSQPSSLAV 
VRGYQPCASF GGSRRQAMPR DSLALQSGQL SDTSQTCRVN GIKMEMKGQP HPLCSNLQNY 
SGQFYDQTVG FSQQDTKAGS FSISDASCLL QGTSAKNSEL LSPGANQVTS TVDSLDSHDL 
EGVQIDFDAI IDDGDHSSLM SGALSPSIIQ NLSHSSSRLT TPRASLPFPA LSMSTTNMAI 
GDMSSLLTSL AEESKFLAVM Q

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.