Details for: GLP1R

Gene ID: 2740

Symbol: GLP1R

Ensembl ID: ENSG00000112164

Description: glucagon like peptide 1 receptor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.4505
    Cell Significance Index: 31.4300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.1577
    Cell Significance Index: 52.4800
  • Cell Name: duodenum glandular cell (CL1001589)
    Fold Change: 1.1489
    Cell Significance Index: 8.2300
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.0984
    Cell Significance Index: 26.6100
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 0.9587
    Cell Significance Index: 16.3900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.8181
    Cell Significance Index: 155.7000
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 0.7961
    Cell Significance Index: 9.6200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6192
    Cell Significance Index: 61.2600
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.5874
    Cell Significance Index: 9.6800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.5351
    Cell Significance Index: 17.1400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4915
    Cell Significance Index: 443.8300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.4310
    Cell Significance Index: 9.1800
  • Cell Name: retinal blood vessel endothelial cell (CL0002585)
    Fold Change: 0.3808
    Cell Significance Index: 4.9200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3150
    Cell Significance Index: 51.2300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3027
    Cell Significance Index: 32.9300
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 0.3004
    Cell Significance Index: 3.0300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1881
    Cell Significance Index: 11.2900
  • Cell Name: epithelial cell of lacrimal sac (CL1000436)
    Fold Change: 0.1848
    Cell Significance Index: 1.3300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1640
    Cell Significance Index: 11.3400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1264
    Cell Significance Index: 87.4500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.1216
    Cell Significance Index: 9.3400
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.1047
    Cell Significance Index: 2.6100
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 0.1009
    Cell Significance Index: 1.3600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0512
    Cell Significance Index: 10.1700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0479
    Cell Significance Index: 1.3800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0477
    Cell Significance Index: 0.9900
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.0222
    Cell Significance Index: 0.1800
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.0156
    Cell Significance Index: 0.2300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0088
    Cell Significance Index: 0.3100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0077
    Cell Significance Index: 0.9000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0062
    Cell Significance Index: 2.2400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0040
    Cell Significance Index: 0.6800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0020
    Cell Significance Index: 0.4000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0018
    Cell Significance Index: 0.0300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0004
    Cell Significance Index: -0.3300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0004
    Cell Significance Index: -0.8200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0005
    Cell Significance Index: -0.9000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0006
    Cell Significance Index: -0.3300
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0009
    Cell Significance Index: -1.3200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0011
    Cell Significance Index: -1.4700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0021
    Cell Significance Index: -0.0300
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0029
    Cell Significance Index: -1.5700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0031
    Cell Significance Index: -1.9600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0032
    Cell Significance Index: -2.0100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0033
    Cell Significance Index: -0.2100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0040
    Cell Significance Index: -0.1000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0041
    Cell Significance Index: -1.8500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0041
    Cell Significance Index: -0.8600
  • Cell Name: pancreatic epsilon cell (CL0005019)
    Fold Change: -0.0054
    Cell Significance Index: -0.0500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0056
    Cell Significance Index: -0.2600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0058
    Cell Significance Index: -1.6600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0058
    Cell Significance Index: -0.6700
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.0090
    Cell Significance Index: -0.1200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0103
    Cell Significance Index: -1.8600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0116
    Cell Significance Index: -1.6800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0150
    Cell Significance Index: -1.8500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0159
    Cell Significance Index: -2.0500
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0166
    Cell Significance Index: -0.2500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0167
    Cell Significance Index: -1.1200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0183
    Cell Significance Index: -1.9100
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.0188
    Cell Significance Index: -0.2600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0195
    Cell Significance Index: -1.2000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0223
    Cell Significance Index: -1.0500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0223
    Cell Significance Index: -1.2500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0226
    Cell Significance Index: -2.3100
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0282
    Cell Significance Index: -0.4100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0308
    Cell Significance Index: -1.6100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0319
    Cell Significance Index: -0.8200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0322
    Cell Significance Index: -2.4000
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0325
    Cell Significance Index: -0.4200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0327
    Cell Significance Index: -0.8900
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0332
    Cell Significance Index: -0.6500
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0343
    Cell Significance Index: -0.4700
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0377
    Cell Significance Index: -0.9600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0407
    Cell Significance Index: -1.8000
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: -0.0419
    Cell Significance Index: -0.5100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0428
    Cell Significance Index: -1.5000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0447
    Cell Significance Index: -1.4300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0454
    Cell Significance Index: -1.7200
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.0454
    Cell Significance Index: -0.6900
  • Cell Name: acinar cell (CL0000622)
    Fold Change: -0.0462
    Cell Significance Index: -0.5800
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0465
    Cell Significance Index: -1.4700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0470
    Cell Significance Index: -1.5400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0490
    Cell Significance Index: -1.0400
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: -0.0534
    Cell Significance Index: -0.3200
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0545
    Cell Significance Index: -0.9400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0555
    Cell Significance Index: -1.5500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0558
    Cell Significance Index: -1.1200
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0560
    Cell Significance Index: -0.8500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0575
    Cell Significance Index: -1.6400
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0579
    Cell Significance Index: -1.1400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0581
    Cell Significance Index: -2.0200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0588
    Cell Significance Index: -1.4100
  • Cell Name: plasmacytoid dendritic cell (CL0000784)
    Fold Change: -0.0591
    Cell Significance Index: -0.7800
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0602
    Cell Significance Index: -0.8400
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0613
    Cell Significance Index: -1.3300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0627
    Cell Significance Index: -1.5700
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0627
    Cell Significance Index: -1.5300
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0637
    Cell Significance Index: -0.9400
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0642
    Cell Significance Index: -1.2700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Structure:** GLP1R is a transmembrane receptor belonging to the secretin family of G-protein coupled receptors. It is characterized by seven transmembrane alpha-helices, a large extracellular N-terminal domain, and a small intracellular C-terminal domain. 2. **Ligand:** The primary ligand for GLP1R is Glucagon-Like Peptide-1 (GLP-1), a 36-amino acid peptide hormone produced by the intestines in response to nutrient ingestion. 3. **Signaling Pathways:** GLP1R activation triggers a complex signaling cascade involving G-proteins, adenylate cyclase, and various downstream effectors, including protein kinase A (PKA), phospholipase C (PLC), and calcium channels. 4. **Expression:** GLP1R is widely expressed in various tissues, including the pancreas, liver, adipose tissue, and the nervous system. **Pathways and Functions:** 1. **Metabolic Regulation:** GLP1R plays a crucial role in regulating glucose homeostasis by stimulating insulin secretion, glycogen synthesis, and energy expenditure. 2. **Cardiovascular Regulation:** GLP1R activation has been shown to regulate blood pressure, cardiac function, and cardiovascular remodeling. 3. **Neurological Functions:** GLP1R has been implicated in learning, memory, and cognitive functions, suggesting a potential role in neuroprotection and neuroregulation. 4. **Energy Metabolism:** GLP1R regulates energy expenditure by modulating fat oxidation, glucose utilization, and appetite regulation. **Clinical Significance:** 1. **Type 2 Diabetes:** GLP1R agonists, such as exenatide and liraglutide, have become a cornerstone in the treatment of type 2 diabetes, improving glycemic control and cardiovascular outcomes. 2. **Obesity and Metabolic Syndrome:** GLP1R agonists have been shown to promote weight loss, improve insulin sensitivity, and reduce cardiovascular risk factors in obese individuals. 3. **Cardiovascular Disease:** GLP1R activation has been implicated in the regulation of blood pressure, cardiac function, and cardiovascular remodeling, making it a potential therapeutic target for cardiovascular disease prevention and treatment. 4. **Neurological Disorders:** The role of GLP1R in neurological functions and neuroprotection suggests potential therapeutic applications in the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's. In conclusion, the Glucagon-Like Peptide 1 Receptor (GLP1R) is a multifunctional receptor that plays a critical role in regulating glucose homeostasis, energy metabolism, and cardiovascular function. Its clinical significance extends beyond its metabolic functions, with implications for the treatment of type 2 diabetes, obesity, and cardiovascular disease, as well as potential therapeutic applications in neurological disorders.

Genular Protein ID: 2596835132

Symbol: GLP1R_HUMAN

Name: Glucagon-like peptide 1 receptor

UniProtKB Accession Codes:

P43220 Q2M229 Q99669

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChEMBL 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 11 DrugCentral 1 EMBL 11 EMDB 33 Ensembl 1 EvolutionaryTrace 1 GO 18 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 48 PDBsum 48 PIR 2 PRINTS 3 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 3 RefSeq 1 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 8405712

Title: Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin-4 is an agonist and exendin-(9-39) an antagonist of the receptor.

PubMed ID: 8405712

DOI: 10.2337/diab.42.11.1678

PubMed ID: 8404634

Title: Cloning and functional expression of the human glucagon-like peptide-1 (GLP-1) receptor.

PubMed ID: 8404634

DOI: 10.1210/endo.133.4.8404634

PubMed ID: 8216285

Title: Cloning and functional expression of a human glucagon-like peptide-1 receptor.

PubMed ID: 8216285

DOI: 10.1006/bbrc.1993.2226

PubMed ID: 7517895

Title: Signal transduction of the GLP-1-receptor cloned from a human insulinoma.

PubMed ID: 7517895

DOI: 10.1016/0014-5793(94)00553-2

PubMed ID: 7843404

Title: Tissue-specific expression of the human receptor for glucagon-like peptide-I: brain, heart and pancreatic forms have the same deduced amino acid sequences.

PubMed ID: 7843404

DOI: 10.1016/0014-5793(94)01430-9

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9213353

Title: Cloning and characterization of the 5' flanking sequences (promoter region) of the human GLP-1 receptor gene.

PubMed ID: 9213353

DOI: 10.1016/s0196-9781(97)00001-6

PubMed ID: 20869417

Title: Functional coupling of Cys-226 and Cys-296 in the glucagon-like peptide-1 (GLP-1) receptor indicates a disulfide bond that is close to the activation pocket.

PubMed ID: 20869417

DOI: 10.1016/j.peptides.2010.09.015

PubMed ID: 21901419

Title: Glucagon like-peptide-1 receptor is covalently modified by endogenous mono-ADP-ribosyltransferase.

PubMed ID: 21901419

DOI: 10.1007/s11033-011-1225-0

PubMed ID: 22412906

Title: Regulation of GIP and GLP1 receptor cell surface expression by N-glycosylation and receptor heteromerization.

PubMed ID: 22412906

DOI: 10.1371/journal.pone.0032675

PubMed ID: 18287102

Title: Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domain.

PubMed ID: 18287102

DOI: 10.1074/jbc.m708740200

PubMed ID: 19861722

Title: Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor.

PubMed ID: 19861722

DOI: 10.1074/jbc.m109.033829

PubMed ID: 26308095

Title: Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide.

PubMed ID: 26308095

DOI: 10.1021/acs.jmedchem.5b00726

PubMed ID: 27196125

Title: Structural insight into antibody-mediated antagonism of the Glucagon-like peptide-1 Receptor.

PubMed ID: 27196125

DOI: 10.1038/srep26236

PubMed ID: 28514449

Title: Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators.

PubMed ID: 28514449

DOI: 10.1038/nature22378

Sequence Information:

  • Length: 463
  • Mass: 53026
  • Checksum: EE7C0EAE29931F5D
  • Sequence:
    • MAGAPGPLRL ALLLLGMVGR AGPRPQGATV SLWETVQKWR EYRRQCQRSL TEDPPPATDL 
FCNRTFDEYA CWPDGEPGSF VNVSCPWYLP WASSVPQGHV YRFCTAEGLW LQKDNSSLPW 
RDLSECEESK RGERSSPEEQ LLFLYIIYTV GYALSFSALV IASAILLGFR HLHCTRNYIH 
LNLFASFILR ALSVFIKDAA LKWMYSTAAQ QHQWDGLLSY QDSLSCRLVF LLMQYCVAAN 
YYWLLVEGVY LYTLLAFSVL SEQWIFRLYV SIGWGVPLLF VVPWGIVKYL YEDEGCWTRN 
SNMNYWLIIR LPILFAIGVN FLIFVRVICI VVSKLKANLM CKTDIKCRLA KSTLTLIPLL 
GTHEVIFAFV MDEHARGTLR FIKLFTELSF TSFQGLMVAI LYCFVNNEVQ LEFRKSWERW 
RLEHLHIQRD SSMKPLKCPT SSLSSGATAG SSMYTATCQA SCS

Genular Protein ID: 3670634888

Symbol: A0A142FHB8_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A142FHB8

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 7 Gene3D 2 InterPro 9 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 3 PROSITE 6 Pfam 2 RefSeq 1 SAM 2 SMART 1 SMR 1 SUPFAM 2

Citations:

PubMed ID: 26936963

Title: Glucagon-like peptide-1 receptor activation attenuates platelet aggregation and thrombosis.

PubMed ID: 26936963

Sequence Information:

  • Length: 463
  • Mass: 53042
  • Checksum: 1C02BC0B2056CD23
  • Sequence:
    • MAGAPGLLRL ALLLLGMVGR AGPRPQGATV SLWETVQKWR EYRRQCQRSL TEDPPPATDL 
FCNRTFDEYA CWPDGEPGSF VNVSCPWYLP WASSVPQGHV YRFCTAEGLW LQKDNSSLPW 
RDLSECEESK RGERSSPEEQ LLFLYIIYTV GYALSFSALV IASAILLGFR HLHCTRNYIH 
LNLFASFILR ALSVFIKDAA LKWMYSTAAQ QHQWDGLLSY QDSLSCRLVF LLMQYCVAAN 
YYWLLVEGVY LYTLLAFSVL SEQWIFRLYV SIGWGVPLLF VVPWGIVKYL YEDEGCWTRN 
SNMNYWLIIR LPILFAIGVN FLIFVRVICI VVSKLKANLM CKTDIKCRLA KSTLTLIPLL 
GTHEVIFAFV MDEHARGTLR FIKLFTELSF TSFQGLMVAI LYCFVNNEVQ LEFRKSWERW 
RLEHLHIQRD SSMKPLKCPT SSLSSGATAG SSMYTATCQA SCS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.