Details for: GRIK3
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 1.4385
Cell Significance Index: 88.4200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 1.3164
Cell Significance Index: 31.5700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 1.2710
Cell Significance Index: 56.2200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.7955
Cell Significance Index: 550.1700 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.6804
Cell Significance Index: 136.4800 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 0.3798
Cell Significance Index: 7.5100 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 0.2606
Cell Significance Index: 8.3000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 0.1885
Cell Significance Index: 6.1700 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.0231
Cell Significance Index: 0.4900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.0150
Cell Significance Index: 0.2200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0067
Cell Significance Index: -2.4100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0080
Cell Significance Index: -0.4500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0105
Cell Significance Index: -19.2800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0107
Cell Significance Index: -20.1800 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0140
Cell Significance Index: -21.5100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0163
Cell Significance Index: -22.1600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0244
Cell Significance Index: -18.0400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0302
Cell Significance Index: -19.2000 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0351
Cell Significance Index: -26.5900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0377
Cell Significance Index: -21.2500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0462
Cell Significance Index: -20.9700 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0594
Cell Significance Index: -10.7100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0712
Cell Significance Index: -20.5000 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: -0.0758
Cell Significance Index: -1.0700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.1021
Cell Significance Index: -20.2700 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1166
Cell Significance Index: -24.5600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1440
Cell Significance Index: -20.9300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1443
Cell Significance Index: -24.6400 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1467
Cell Significance Index: -3.6600 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1501
Cell Significance Index: -19.2400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1595
Cell Significance Index: -19.6100 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1735
Cell Significance Index: -22.4200 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.1793
Cell Significance Index: -24.6200 - Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
Fold Change: -0.1986
Cell Significance Index: -1.0400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2133
Cell Significance Index: -24.4400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2186
Cell Significance Index: -6.1100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.2211
Cell Significance Index: -23.0200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.2259
Cell Significance Index: -23.0800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2965
Cell Significance Index: -22.1000 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.3174
Cell Significance Index: -24.3600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.3422
Cell Significance Index: -23.0100 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: -0.3504
Cell Significance Index: -5.9900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3524
Cell Significance Index: -22.2100 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.3566
Cell Significance Index: -4.5000 - Cell Name: neural cell (CL0002319)
Fold Change: -0.3849
Cell Significance Index: -4.4900 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3891
Cell Significance Index: -13.6300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.3899
Cell Significance Index: -18.3300 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.3923
Cell Significance Index: -25.3100 - Cell Name: neuron (CL0000540)
Fold Change: -0.3935
Cell Significance Index: -3.7300 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.4383
Cell Significance Index: -23.0200 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.5057
Cell Significance Index: -5.5100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.5159
Cell Significance Index: -13.2600 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: -0.5351
Cell Significance Index: -6.9400 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -0.5937
Cell Significance Index: -7.1000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.5941
Cell Significance Index: -30.8600 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.6133
Cell Significance Index: -7.7400 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.6236
Cell Significance Index: -12.5200 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.6264
Cell Significance Index: -23.7200 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.6732
Cell Significance Index: -8.9800 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.6819
Cell Significance Index: -23.9600 - Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: -0.6879
Cell Significance Index: -7.5900 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.6964
Cell Significance Index: -24.2000 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.7183
Cell Significance Index: -17.4000 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.7408
Cell Significance Index: -21.1400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.7730
Cell Significance Index: -22.1600 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.7759
Cell Significance Index: -24.5400 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: -0.8055
Cell Significance Index: -8.3400 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.8148
Cell Significance Index: -24.0000 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.8150
Cell Significance Index: -11.5800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.8288
Cell Significance Index: -23.8800 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.8321
Cell Significance Index: -20.7500 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.8360
Cell Significance Index: -21.3000 - Cell Name: skeletal muscle fibroblast (CL0011027)
Fold Change: -0.8885
Cell Significance Index: -6.0200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.8898
Cell Significance Index: -23.7600 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.9069
Cell Significance Index: -24.3000 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.9152
Cell Significance Index: -19.1000 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: -0.9283
Cell Significance Index: -9.6700 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.9298
Cell Significance Index: -24.4500 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.9437
Cell Significance Index: -20.3900 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.9503
Cell Significance Index: -23.7400 - Cell Name: medial ganglionic eminence derived GABAergic cortical interneuron (CL4023069)
Fold Change: -0.9518
Cell Significance Index: -8.9900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.9696
Cell Significance Index: -21.2300 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: -0.9708
Cell Significance Index: -12.6700 - Cell Name: interneuron (CL0000099)
Fold Change: -0.9708
Cell Significance Index: -11.3400 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: -0.9710
Cell Significance Index: -13.3200 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.9716
Cell Significance Index: -16.6500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.9725
Cell Significance Index: -24.3100 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.9841
Cell Significance Index: -20.0300 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: -0.9924
Cell Significance Index: -8.8100 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.9942
Cell Significance Index: -20.8100 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -1.0465
Cell Significance Index: -25.5400 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -1.0833
Cell Significance Index: -18.7300 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -1.0898
Cell Significance Index: -21.4500 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -1.1051
Cell Significance Index: -13.7800 - Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
Fold Change: -1.1078
Cell Significance Index: -22.0900 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -1.1436
Cell Significance Index: -24.4500 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -1.1676
Cell Significance Index: -24.2200 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -1.2135
Cell Significance Index: -17.2800 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -1.2444
Cell Significance Index: -24.3300 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -1.2446
Cell Significance Index: -16.5900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2350861067
Symbol: GRIK3_HUMAN
Name: Glutamate receptor ionotropic, kainate 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7719709
Title: Molecular characterization of the human EAA5 (GluR7) receptor: a high-affinity kainate receptor with novel potential RNA editing sites.
PubMed ID: 7719709
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 8128318
Title: Chromosomal localization of gene for human glutamate receptor subunit-7.
PubMed ID: 8128318
DOI: 10.1007/bf01233385
PubMed ID: 11124978
Title: Unequal expression of allelic kainate receptor GluR7 mRNAs in human brains.
PubMed ID: 11124978
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
Sequence Information:
- Length: 919
- Mass: 104037
- Checksum: 0F68F6CF33E4CE71
- Sequence:
MTAPWRRLRS LVWEYWAGLL VCAFWIPDSR GMPHVIRIGG IFEYADGPNA QVMNAEEHAF RFSANIINRN RTLLPNTTLT YDIQRIHFHD SFEATKKACD QLALGVVAIF GPSQGSCTNA VQSICNALEV PHIQLRWKHH PLDNKDTFYV NLYPDYASLS HAILDLVQYL KWRSATVVYD DSTGLIRLQE LIMAPSRYNI RLKIRQLPID SDDSRPLLKE MKRGREFRII FDCSHTMAAQ ILKQAMAMGM MTEYYHFIFT TLDLYALDLE PYRYSGVNLT GFRILNVDNP HVSAIVEKWS MERLQAAPRS ESGLLDGVMM TDAALLYDAV HIVSVCYQRA PQMTVNSLQC HRHKAWRFGG RFMNFIKEAQ WEGLTGRIVF NKTSGLRTDF DLDIISLKED GLEKVGVWSP ADGLNITEVA KGRGPNVTDS LTNRSLIVTT VLEEPFVMFR KSDRTLYGND RFEGYCIDLL KELAHILGFS YEIRLVEDGK YGAQDDKGQW NGMVKELIDH KADLAVAPLT ITHVREKAID FSKPFMTLGV SILYRKPNGT NPSVFSFLNP LSPDIWMYVL LAYLGVSCVL FVIARFSPYE WYDAHPCNPG SEVVENNFTL LNSFWFGMGS LMQQGSELMP KALSTRIIGG IWWFFTLIII SSYTANLAAF LTVERMESPI DSADDLAKQT KIEYGAVKDG ATMTFFKKSK ISTFEKMWAF MSSKPSALVK NNEEGIQRAL TADYALLMES TTIEYVTQRN CNLTQIGGLI DSKGYGIGTP MGSPYRDKIT IAILQLQEED KLHIMKEKWW RGSGCPEEEN KEASALGIQK IGGIFIVLAA GLVLSVLVAV GEFVYKLRKT AEREQRSFCS TVADEIRFSL TCQRRVKHKP QPPMMVKTDA VINMHTFNDR RLPGKDSMAC STSLAPVFP
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.