Details for: GSTA1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: epithelial cell of exocrine pancreas (CL1001433)
Fold Change: 97.4788
Cell Significance Index: 48.9600 - Cell Name: precursor cell (CL0011115)
Fold Change: 32.7258
Cell Significance Index: 248.1600 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 28.8265
Cell Significance Index: 431.9400 - Cell Name: Leydig cell (CL0000178)
Fold Change: 20.6442
Cell Significance Index: 102.9900 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 11.3518
Cell Significance Index: -30.4100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 7.0846
Cell Significance Index: 204.1200 - Cell Name: Sertoli cell (CL0000216)
Fold Change: 5.6999
Cell Significance Index: 79.9500 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 5.4734
Cell Significance Index: 146.6600 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 3.5437
Cell Significance Index: 51.4500 - Cell Name: hepatoblast (CL0005026)
Fold Change: 3.3551
Cell Significance Index: 56.4300 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 3.1885
Cell Significance Index: 32.8900 - Cell Name: granulosa cell (CL0000501)
Fold Change: 2.9213
Cell Significance Index: 76.8200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 2.7163
Cell Significance Index: 163.0700 - Cell Name: tuft cell of small intestine (CL0009080)
Fold Change: 2.6081
Cell Significance Index: 26.3100 - Cell Name: fraction A pre-pro B cell (CL0002045)
Fold Change: 2.4809
Cell Significance Index: 29.3200 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 1.9247
Cell Significance Index: 209.3500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 1.8415
Cell Significance Index: 1662.7600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 1.6774
Cell Significance Index: 41.9300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.8504
Cell Significance Index: 138.3100 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: 0.8215
Cell Significance Index: 65.0600 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.7465
Cell Significance Index: 148.1400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.5651
Cell Significance Index: 107.5400 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.3055
Cell Significance Index: 7.4000 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.2836
Cell Significance Index: 6.0400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.2594
Cell Significance Index: 17.9400 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.2342
Cell Significance Index: 8.2300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: 0.1787
Cell Significance Index: 131.0300 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1599
Cell Significance Index: 15.8200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 0.1575
Cell Significance Index: 26.9000 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 0.1328
Cell Significance Index: 1.9600 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.0947
Cell Significance Index: 0.9800 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.0620
Cell Significance Index: 0.9600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0540
Cell Significance Index: 1.7300 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: 0.0419
Cell Significance Index: 4.8900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0250
Cell Significance Index: 4.5100 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 0.0246
Cell Significance Index: 0.4200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0201
Cell Significance Index: 0.9100 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 0.0184
Cell Significance Index: 0.1200 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0104
Cell Significance Index: 5.6800 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: 0.0062
Cell Significance Index: 0.2700 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0015
Cell Significance Index: -0.0200 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0021
Cell Significance Index: -0.2800 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0042
Cell Significance Index: -3.1500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0133
Cell Significance Index: -25.1000 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0134
Cell Significance Index: -0.5500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0170
Cell Significance Index: -31.4300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0192
Cell Significance Index: -0.5400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0200
Cell Significance Index: -1.0100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0205
Cell Significance Index: -31.5000 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0232
Cell Significance Index: -31.5000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0285
Cell Significance Index: -3.5100 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0291
Cell Significance Index: -0.6300 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0297
Cell Significance Index: -3.8100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0304
Cell Significance Index: -13.4600 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: -0.0321
Cell Significance Index: -0.3000 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0334
Cell Significance Index: -24.7500 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0373
Cell Significance Index: -0.9600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0390
Cell Significance Index: -24.7700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0408
Cell Significance Index: -25.4900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0441
Cell Significance Index: -24.8600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0577
Cell Significance Index: -26.1900 - Cell Name: eosinophil (CL0000771)
Fold Change: -0.0699
Cell Significance Index: -0.6200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0842
Cell Significance Index: -8.6100 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0956
Cell Significance Index: -1.4400 - Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
Fold Change: -0.0983
Cell Significance Index: -0.5200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1232
Cell Significance Index: -14.1200 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.1269
Cell Significance Index: -25.4500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.1344
Cell Significance Index: -18.4600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1398
Cell Significance Index: -29.4500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1398
Cell Significance Index: -9.8900 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.1526
Cell Significance Index: -1.7300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1698
Cell Significance Index: -24.6800 - Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: -0.1988
Cell Significance Index: -1.5200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2047
Cell Significance Index: -12.5500 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.2615
Cell Significance Index: -7.0000 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.3099
Cell Significance Index: -14.4500 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: -0.3389
Cell Significance Index: -4.3400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.3420
Cell Significance Index: -16.0800 - Cell Name: epithelial cell (CL0000066)
Fold Change: -0.3460
Cell Significance Index: -3.6500 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: -0.3472
Cell Significance Index: -4.3000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.3905
Cell Significance Index: -26.2600 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.3929
Cell Significance Index: -29.2800 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3940
Cell Significance Index: -24.8300 - Cell Name: lung ciliated cell (CL1000271)
Fold Change: -0.4094
Cell Significance Index: -4.0100 - Cell Name: colonocyte (CL1000347)
Fold Change: -0.4159
Cell Significance Index: -2.5700 - Cell Name: peg cell (CL4033014)
Fold Change: -0.4160
Cell Significance Index: -9.6100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.4666
Cell Significance Index: -28.6800 - Cell Name: progenitor cell (CL0011026)
Fold Change: -0.4744
Cell Significance Index: -5.0400 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.4815
Cell Significance Index: -7.9400 - Cell Name: enterocyte (CL0000584)
Fold Change: -0.5094
Cell Significance Index: -3.1600 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: -0.5157
Cell Significance Index: -2.9700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.5192
Cell Significance Index: -26.9700 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.5298
Cell Significance Index: -29.7300 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.5366
Cell Significance Index: -19.7000 - Cell Name: tracheal goblet cell (CL1000329)
Fold Change: -0.6381
Cell Significance Index: -5.2800 - Cell Name: secretory cell (CL0000151)
Fold Change: -0.6417
Cell Significance Index: -4.4500 - Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: -0.6478
Cell Significance Index: -8.3700 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.6524
Cell Significance Index: -28.8600 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.6964
Cell Significance Index: -11.6600 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.7168
Cell Significance Index: -25.1100
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 487563818
Symbol: GSTA1_HUMAN
Name: GST HA subunit 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3800996
Title: Human liver glutathione S-transferases: complete primary sequence of an Ha subunit cDNA.
PubMed ID: 3800996
PubMed ID: 3036131
Title: The basic glutathione S-transferases from human livers are products of separate genes.
PubMed ID: 3036131
PubMed ID: 3678589
Title: Nucleotide sequence of the human liver glutathione S-transferase subunit 1 cDNA.
PubMed ID: 3678589
DOI: 10.1042/bst0150734
PubMed ID: 3031680
Title: Isolation of a cDNA clone and localization of human glutathione S-transferase 2 genes to chromosome band 6p12.
PubMed ID: 3031680
PubMed ID: 1731620
Title: Isolation and characterization of a human glutathione S-transferase Ha1 subunit gene.
PubMed ID: 1731620
PubMed ID: 1330133
Title: Heterologous expression of recombinant human glutathione transferase A1-1 from a hepatoma cell line.
PubMed ID: 1330133
PubMed ID: 14574404
Title: The DNA sequence and analysis of human chromosome 6.
PubMed ID: 14574404
DOI: 10.1038/nature02055
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 3138230
Title: Human glutathione S-transferases. The Ha multigene family encodes products of different but overlapping substrate specificities.
PubMed ID: 3138230
PubMed ID: 8431482
Title: Characterization of two novel subunits of the alpha-class glutathione S-transferases of human liver.
PubMed ID: 8431482
PubMed ID: 2604726
Title: Evidence that glutathione S-transferases B1B1 and B2B2 are the products of separate genes and that their expression in human liver is subject to inter-individual variation. Molecular relationships between the B1 and B2 subunits and other alpha class glutathione S-transferases.
PubMed ID: 2604726
DOI: 10.1042/bj2640437
PubMed ID: 2018473
Title: The contribution of the C-terminal sequence to the catalytic activity of GST2, a human alpha-class glutathione transferase.
PubMed ID: 2018473
DOI: 10.1042/bj2750171
PubMed ID: 9084911
Title: Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1.
PubMed ID: 9084911
DOI: 10.1021/tx9601770
PubMed ID: 11152686
Title: The role of glutathione in the isomerization of delta 5-androstene-3,17-dione catalyzed by human glutathione transferase A1-1.
PubMed ID: 11152686
PubMed ID: 16624487
Title: Metabolism of oxidized linoleic acid by glutathione transferases: peroxidase activity toward 13-hydroperoxyoctadecadienoic acid.
PubMed ID: 16624487
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 8331657
Title: Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes.
PubMed ID: 8331657
PubMed ID: 8591048
Title: Structural analysis of human alpha-class glutathione transferase A1-1 in the apo-form and in complexes with ethacrynic acid and its glutathione conjugate.
PubMed ID: 8591048
PubMed ID: 12211029
Title: 1.3-A resolution structure of human glutathione S-transferase with S-hexyl glutathione bound reveals possible extended ligandin binding site.
PubMed ID: 12211029
DOI: 10.1002/prot.10162
PubMed ID: 15333749
Title: Incorporation of a single His residue by rational design enables thiol-ester hydrolysis by human glutathione transferase A1-1.
PubMed ID: 15333749
PubMed ID: 15893769
Title: Tertiary interactions stabilise the C-terminal region of human glutathione transferase A1-1: a crystallographic and calorimetric study.
PubMed ID: 15893769
PubMed ID: 16421451
Title: New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
PubMed ID: 16421451
PubMed ID: 19618965
Title: Structural analysis of a glutathione transferase A1-1 mutant tailored for high catalytic efficiency with toxic alkenals.
PubMed ID: 19618965
DOI: 10.1021/bi900895b
PubMed ID: 20606271
Title: The role of a topologically conserved isoleucine in glutathione transferase structure, stability and function.
PubMed ID: 20606271
Sequence Information:
- Length: 222
- Mass: 25631
- Checksum: C8B6786DCD761350
- Sequence:
MAEKPKLHYF NARGRMESTR WLLAAAGVEF EEKFIKSAED LDKLRNDGYL MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKERA LIDMYIEGIA DLGEMILLLP VCPPEEKDAK LALIKEKIKN RYFPAFEKVL KSHGQDYLVG NKLSRADIHL VELLYYVEEL DSSLISSFPL LKALKTRISN LPTVKKFLQP GSPRKPPMDE KSLEEARKIF RF
Genular Protein ID: 1303165266
Symbol: B7Z1F9_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 225
- Mass: 25648
- Checksum: 10E7597C948D5DF2
- Sequence:
MAEKPKLHYF NARGRMESTR WLLAAAGVEF EEKFIKSAED LDKLRNDGYL MFQQVPMVEI DGMKLVQTRA ILNYIASKYN LYGKDIKERA LIDMYIEGIA DLGEMILLLP VCPPEEKDAK LALIKEKIKN RYFPAFEKVL KSHGQDYLVG NKLSRADIHL VELLYYVEEL DSSLISSFPL LKVTHFTAQR GSPTSPILGS CIWALRLTKF CPSLLQAFSA PRSPK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.