Details for: ZDHHC8

Gene ID: 29801

Symbol: ZDHHC8

Ensembl ID: ENSG00000099904

Description: zinc finger DHHC-type palmitoyltransferase 8

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 96.7564
    Cell Significance Index: -15.0500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 56.3784
    Cell Significance Index: -14.3000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 12.2510
    Cell Significance Index: -15.1100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 5.5285
    Cell Significance Index: -14.8100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.8418
    Cell Significance Index: -15.1600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 2.9009
    Cell Significance Index: -8.9100
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.4582
    Cell Significance Index: -5.3800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.0731
    Cell Significance Index: 106.1500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.7889
    Cell Significance Index: 712.3500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.6795
    Cell Significance Index: 18.9900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6634
    Cell Significance Index: 133.0700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5536
    Cell Significance Index: 60.2200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.5449
    Cell Significance Index: 88.6200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4871
    Cell Significance Index: 29.2400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.4196
    Cell Significance Index: 5.7300
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.2998
    Cell Significance Index: 4.8100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2917
    Cell Significance Index: 13.2200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.2885
    Cell Significance Index: 6.2500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2801
    Cell Significance Index: 193.7400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.2720
    Cell Significance Index: 14.1300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2642
    Cell Significance Index: 18.2700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.2604
    Cell Significance Index: 93.4000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.2402
    Cell Significance Index: 32.9800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2169
    Cell Significance Index: 6.2500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.2018
    Cell Significance Index: 36.3900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.1917
    Cell Significance Index: 12.3700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1732
    Cell Significance Index: 34.3800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1465
    Cell Significance Index: 18.0100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.1205
    Cell Significance Index: 53.2700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1039
    Cell Significance Index: 19.7800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0986
    Cell Significance Index: 7.5700
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0975
    Cell Significance Index: 53.2500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0907
    Cell Significance Index: 4.2300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0852
    Cell Significance Index: 5.3700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0826
    Cell Significance Index: 5.8400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0795
    Cell Significance Index: 5.3500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0633
    Cell Significance Index: 8.1200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0435
    Cell Significance Index: 1.5300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.0405
    Cell Significance Index: 2.2700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0396
    Cell Significance Index: 0.9900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0216
    Cell Significance Index: 0.6200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0194
    Cell Significance Index: 0.5200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0189
    Cell Significance Index: 34.9200
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0178
    Cell Significance Index: 27.4800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0122
    Cell Significance Index: 22.9500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0100
    Cell Significance Index: 13.5800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0036
    Cell Significance Index: 2.2700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0020
    Cell Significance Index: -0.3400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0072
    Cell Significance Index: -3.2800
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.0084
    Cell Significance Index: -0.0900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0115
    Cell Significance Index: -8.4100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0135
    Cell Significance Index: -10.2400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0140
    Cell Significance Index: -0.6200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0160
    Cell Significance Index: -2.3300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0183
    Cell Significance Index: -0.8600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0192
    Cell Significance Index: -14.2200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0256
    Cell Significance Index: -14.4300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0276
    Cell Significance Index: -17.2700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0343
    Cell Significance Index: -1.3000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0352
    Cell Significance Index: -0.7700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0408
    Cell Significance Index: -1.1100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0442
    Cell Significance Index: -12.7100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0487
    Cell Significance Index: -4.9800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0559
    Cell Significance Index: -6.5200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0564
    Cell Significance Index: -6.6500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0672
    Cell Significance Index: -4.1300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0708
    Cell Significance Index: -2.0200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0732
    Cell Significance Index: -9.4600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0806
    Cell Significance Index: -16.9800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0933
    Cell Significance Index: -10.6900
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1043
    Cell Significance Index: -1.7500
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.1059
    Cell Significance Index: -1.6800
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.1129
    Cell Significance Index: -1.5900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.1164
    Cell Significance Index: -2.4800
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.1222
    Cell Significance Index: -1.6300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.1282
    Cell Significance Index: -2.6600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1321
    Cell Significance Index: -13.7500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1385
    Cell Significance Index: -3.7000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1430
    Cell Significance Index: -4.5800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1462
    Cell Significance Index: -3.8500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1471
    Cell Significance Index: -10.9600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1473
    Cell Significance Index: -2.1100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1683
    Cell Significance Index: -10.3200
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1718
    Cell Significance Index: -13.6100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1735
    Cell Significance Index: -9.1100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1844
    Cell Significance Index: -4.7400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1920
    Cell Significance Index: -3.2900
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.2034
    Cell Significance Index: -2.9200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.2035
    Cell Significance Index: -3.0100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2169
    Cell Significance Index: -4.5400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2249
    Cell Significance Index: -6.0200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2348
    Cell Significance Index: -8.1600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2355
    Cell Significance Index: -7.5000
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2365
    Cell Significance Index: -5.0200
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.2407
    Cell Significance Index: -12.5400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2660
    Cell Significance Index: -8.7100
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.2716
    Cell Significance Index: -1.8400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.2742
    Cell Significance Index: -2.5300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3032
    Cell Significance Index: -10.6200
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3038
    Cell Significance Index: -7.7600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** ZDHHC8 is a zinc finger DHHC-type palmitoyltransferase, a type of enzyme that catalyzes the post-translational modification of cysteine residues in proteins, leading to their palmitoylation. This post-translational modification plays a critical role in regulating protein localization, protein-protein interactions, and signaling pathways. The unique characteristics of ZDHHC8, including its specificity for palmitoyltransferase activity and its involvement in various cellular processes, make it an attractive target for further investigation. **Pathways and Functions:** ZDHHC8 is implicated in several cellular pathways, including: 1. **Protein Palmitoylation**: ZDHHC8 is responsible for palmitoylating cysteine residues in proteins, which is essential for regulating protein localization, protein-protein interactions, and signaling pathways. 2. **Cholesterol Efflux**: ZDHHC8 has been shown to positively regulate cholesterol efflux, a critical process in maintaining lipid homeostasis and preventing atherosclerosis. 3. **Viral Infection Pathways**: ZDHHC8 is involved in the regulation of viral infection pathways, including the maturation of spike proteins and the positive regulation of viral replication. 4. **Immune Response**: ZDHHC8 is expressed in various immune cells, including GABAergic interneurons, cardiac muscle myoblasts, and intestinal epithelial cells, suggesting its potential role in regulating immune responses. **Clinical Significance:** The identification of ZDHHC8 as a key regulator of protein localization, cholesterol efflux, and viral infection pathways has significant implications for the understanding and treatment of various diseases, including: 1. **Atherosclerosis**: ZDHHC8's involvement in cholesterol efflux makes it a potential target for the development of novel therapeutic strategies for preventing and treating atherosclerosis. 2. **Viral Infections**: ZDHHC8's role in regulating viral infection pathways makes it a potential target for the development of antiviral therapies. 3. **Immunological Disorders**: ZDHHC8's expression in immune cells suggests its potential role in regulating immune responses, making it a potential target for the development of novel immunotherapies. In conclusion, ZDHHC8 is a critical regulator of protein localization, cholesterol efflux, and viral infection pathways, with significant implications for the understanding and treatment of various diseases. Further investigation into the functional significance of ZDHHC8 is necessary to fully elucidate its role in immunological processes and to develop novel therapeutic strategies.

Genular Protein ID: 1148053368

Symbol: ZDHC8_HUMAN

Name: Zinc finger protein 378

UniProtKB Accession Codes:

Q9ULC8 Q2TGE9 Q6ICL1 Q6ZNF5 Q7Z6L9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CTD 1 ChEBI 4 DMDM 1 DNASU 1 DisGeNET 1 EC 1 EMBL 7 Ensembl 3 ExpressionAtlas 1 GO 13 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 2 RefSeq 3 Rhea 4 SMR 1 STRING 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10591208

Title: The DNA sequence of human chromosome 22.

PubMed ID: 10591208

DOI: 10.1038/990031

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15461802

Title: A genome annotation-driven approach to cloning the human ORFeome.

PubMed ID: 15461802

DOI: 10.1186/gb-2004-5-10-r84

PubMed ID: 10574462

Title: Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10574462

DOI: 10.1093/dnares/6.5.337

PubMed ID: 15489219

Title: Case-control study and transmission disequilibrium test provide consistent evidence for association between schizophrenia and genetic variation in the 22q11 gene ZDHHC8.

PubMed ID: 15489219

DOI: 10.1093/hmg/ddh322

PubMed ID: 15184899

Title: Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia.

PubMed ID: 15184899

DOI: 10.1038/ng1375

PubMed ID: 15992527

Title: No association between the putative functional ZDHHC8 single nucleotide polymorphism rs175174 and schizophrenia in large European samples.

PubMed ID: 15992527

DOI: 10.1016/j.biopsych.2005.03.017

PubMed ID: 15631889

Title: No association was found between a functional SNP in ZDHHC8 and schizophrenia in a Japanese case-control population.

PubMed ID: 15631889

DOI: 10.1016/j.neulet.2004.10.015

PubMed ID: 16150541

Title: The ZDHHC8 gene did not associate with bipolar disorder or schizophrenia.

PubMed ID: 16150541

DOI: 10.1016/j.neulet.2005.08.019

PubMed ID: 16647879

Title: Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins.

PubMed ID: 16647879

DOI: 10.1016/j.bbalip.2006.03.010

PubMed ID: 18220336

Title: Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis.

PubMed ID: 18220336

DOI: 10.1021/pr0705441

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 19556522

Title: Palmitoylation of ATP-binding cassette transporter A1 is essential for its trafficking and function.

PubMed ID: 19556522

DOI: 10.1161/circresaha.108.193011

PubMed ID: 23034182

Title: Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system.

PubMed ID: 23034182

DOI: 10.1091/mbc.e12-05-0336

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26535572

Title: Effect of C-Terminal S-Palmitoylation on D2 Dopamine Receptor Trafficking and Stability.

PubMed ID: 26535572

DOI: 10.1371/journal.pone.0140661

PubMed ID: 34599882

Title: S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity.

PubMed ID: 34599882

DOI: 10.1016/j.devcel.2021.09.016

Sequence Information:

  • Length: 765
  • Mass: 81443
  • Checksum: 005FCA33D7FD7397
  • Sequence:
    • MPRSPGTRLK PAKYIPVATA AALLVGSSTL FFVFTCPWLT RAVSPAVPVY NGIIFLFVLA 
NFSMATFMDP GVFPRADEDE DKEDDFRAPL YKNVDVRGIQ VRMKWCATCH FYRPPRCSHC 
SVCDNCVEDF DHHCPWVNNC IGRRNYRYFF LFLLSLSAHM VGVVAFGLVY VLNHAEGLGA 
AHTTITMAVM CVAGLFFIPV IGLTGFHVVL VTRGRTTNEQ VTGKFRGGVN PFTRGCCGNV 
EHVLCSPLAP RYVVEPPRLP LAVSLKPPFL RPELLDRAAP LKVKLSDNGL KAGLGRSKSK 
GSLDRLDEKP LDLGPPLPPK IEAGTFSSDL QTPRPGSAES ALSVQRTSPP TPAMYKFRPA 
FPTGPKVPFC GPGEQVPGPD SLTLGDDSIR SLDFVSEPSL DLPDYGPGGL HAAYPPSPPL 
SASDAFSGAL RSLSLKASSR RGGDHVALQP LRSEGGPPTP HRSIFAPHAL PNRNGSLSYD 
SLLNPGSPGG HACPAHPAVG VAGYHSPYLH PGATGDPPRP LPRSFSPVLG PRPREPSPVR 
YDNLSRTIMA SIQERKDREE RERLLRSQAD SLFGDSGVYD APSSYSLQQA SVLSEGPRGP 
ALRYGSRDDL VAGPGFGGAR NPALQTSLSS LSSSVSRAPR TSSSSLQADQ ASSNAPGPRP 
SSGSHRSPAR QGLPSPPGTP HSPSYAGPKA VAFIHTDLPE PPPSLTVQRD HPQLKTPPSK 
LNGQSPGLAR LGPATGPPGP SASPTRHTLV KKVSGVGGTT YEISV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.