Details for: GYS1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 123.3082
Cell Significance Index: -19.1800 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 73.8044
Cell Significance Index: -18.7200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 41.5254
Cell Significance Index: -16.8700 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 17.6906
Cell Significance Index: -16.8900 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 15.7670
Cell Significance Index: -19.4400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 7.2083
Cell Significance Index: -19.3100 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.9518
Cell Significance Index: -19.5400 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 4.7336
Cell Significance Index: -10.3600 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 1.5722
Cell Significance Index: 38.3600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.5433
Cell Significance Index: 39.6700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 1.2401
Cell Significance Index: 95.1600 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.0075
Cell Significance Index: 99.6600 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.9957
Cell Significance Index: 26.6800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.8997
Cell Significance Index: 180.4800 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.8741
Cell Significance Index: 789.2400 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.7858
Cell Significance Index: 21.9600 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 0.6780
Cell Significance Index: 10.9400 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.6392
Cell Significance Index: 126.8500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.6310
Cell Significance Index: 68.6300 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.5524
Cell Significance Index: 89.8400 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: 0.5225
Cell Significance Index: 8.6100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.4985
Cell Significance Index: 178.8200 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.4766
Cell Significance Index: 329.6000 - Cell Name: subcutaneous adipocyte (CL0002521)
Fold Change: 0.4755
Cell Significance Index: 2.0700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.4509
Cell Significance Index: 12.9900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.4206
Cell Significance Index: 21.8500 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.4046
Cell Significance Index: 5.5200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.3995
Cell Significance Index: 18.1100 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.3643
Cell Significance Index: 22.9600 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.3361
Cell Significance Index: 7.1900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3170
Cell Significance Index: 57.1500 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3116
Cell Significance Index: 21.5500 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.2452
Cell Significance Index: 30.1600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.2384
Cell Significance Index: 5.9600 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: 0.2239
Cell Significance Index: 3.3100 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.1314
Cell Significance Index: 3.7500 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.1065
Cell Significance Index: 58.1800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.1006
Cell Significance Index: 6.7700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0716
Cell Significance Index: 134.8200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0706
Cell Significance Index: 32.0400 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0581
Cell Significance Index: 89.5100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.0536
Cell Significance Index: 2.3700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0456
Cell Significance Index: 20.1700 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0450
Cell Significance Index: 1.5800 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0395
Cell Significance Index: 72.9200 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.0361
Cell Significance Index: 0.4300 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.0297
Cell Significance Index: 0.6500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0286
Cell Significance Index: 3.9300 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0282
Cell Significance Index: 17.8900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0181
Cell Significance Index: 24.6100 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.0124
Cell Significance Index: 0.4700 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.0122
Cell Significance Index: 0.2700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0116
Cell Significance Index: 0.7100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.0037
Cell Significance Index: 0.2100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.0033
Cell Significance Index: 0.4200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0005
Cell Significance Index: -0.0600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0023
Cell Significance Index: -0.0400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0158
Cell Significance Index: -11.9900 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0185
Cell Significance Index: -13.5400 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0238
Cell Significance Index: -1.1100 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0266
Cell Significance Index: -19.7000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0337
Cell Significance Index: -0.9000 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0358
Cell Significance Index: -22.3600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0367
Cell Significance Index: -20.7200 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0454
Cell Significance Index: -4.6400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0460
Cell Significance Index: -0.9800 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0590
Cell Significance Index: -16.9700 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0645
Cell Significance Index: -11.0200 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0693
Cell Significance Index: -10.0700 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.0817
Cell Significance Index: -1.3100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0908
Cell Significance Index: -9.4600 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0931
Cell Significance Index: -12.0300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0949
Cell Significance Index: -4.4600 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1030
Cell Significance Index: -12.0000 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1054
Cell Significance Index: -22.1900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.1118
Cell Significance Index: -7.2200 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.1133
Cell Significance Index: -3.6300 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1181
Cell Significance Index: -2.4500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1324
Cell Significance Index: -15.1700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1484
Cell Significance Index: -4.0400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.1668
Cell Significance Index: -11.8000 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.1897
Cell Significance Index: -14.1400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2198
Cell Significance Index: -17.4100 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: -0.2220
Cell Significance Index: -1.8100 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.2226
Cell Significance Index: -13.6500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.2320
Cell Significance Index: -12.1800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.2379
Cell Significance Index: -5.0500 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.2542
Cell Significance Index: -4.2600 - Cell Name: hippocampal astrocyte (CL0002604)
Fold Change: -0.2739
Cell Significance Index: -3.8300 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.2780
Cell Significance Index: -2.5600 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.2896
Cell Significance Index: -6.9500 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.2932
Cell Significance Index: -8.6100 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2946
Cell Significance Index: -5.7500 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.2978
Cell Significance Index: -15.5100 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.3058
Cell Significance Index: -8.0400 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.3205
Cell Significance Index: -4.5900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3699
Cell Significance Index: -11.7800 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.3865
Cell Significance Index: -8.3500 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3980
Cell Significance Index: -13.0300 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: -0.4089
Cell Significance Index: -2.5300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1444685186
Symbol: GYS1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2493642
Title: Human muscle glycogen synthase cDNA sequence: a negatively charged protein with an asymmetric charge distribution.
PubMed ID: 2493642
PubMed ID: 7657035
Title: Isolation and characterization of the human muscle glycogen synthase gene.
PubMed ID: 7657035
PubMed ID: 9010351
Title: Cloning and characterization of a glycogen synthase cDNA from human endometrium.
PubMed ID: 9010351
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17055998
Title: Interaction between glycogenin and glycogen synthase.
PubMed ID: 17055998
PubMed ID: 17928598
Title: Cardiomyopathy and exercise intolerance in muscle glycogen storage disease 0.
PubMed ID: 17928598
DOI: 10.1056/nejmoa066691
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19413330
Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
PubMed ID: 19413330
DOI: 10.1021/ac9004309
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21668450
Title: R3F, a novel membrane-associated glycogen targeting subunit of protein phosphatase 1 regulates glycogen synthase in astrocytoma cells in response to glucose and extracellular signals.
PubMed ID: 21668450
PubMed ID: 21406692
Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
PubMed ID: 21406692
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 35690592
Title: Mechanism of glycogen synthase inactivation and interaction with glycogenin.
PubMed ID: 35690592
PubMed ID: 35835870
Title: Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate.
PubMed ID: 35835870
Sequence Information:
- Length: 737
- Mass: 83786
- Checksum: 0E321BBFDEB0BD7F
- Sequence:
MPLNRTLSMS SLPGLEDWED EFDLENAVLF EVAWEVANKV GGIYTVLQTK AKVTGDEWGD NYFLVGPYTE QGVRTQVELL EAPTPALKRT LDSMNSKGCK VYFGRWLIEG GPLVVLLDVG ASAWALERWK GELWDTCNIG VPWYDREAND AVLFGFLTTW FLGEFLAQSE EKPHVVAHFH EWLAGVGLCL CRARRLPVAT IFTTHATLLG RYLCAGAVDF YNNLENFNVD KEAGERQIYH RYCMERAAAH CAHVFTTVSQ ITAIEAQHLL KRKPDIVTPN GLNVKKFSAM HEFQNLHAQS KARIQEFVRG HFYGHLDFNL DKTLYFFIAG RYEFSNKGAD VFLEALARLN YLLRVNGSEQ TVVAFFIMPA RTNNFNVETL KGQAVRKQLW DTANTVKEKF GRKLYESLLV GSLPDMNKML DKEDFTMMKR AIFATQRQSF PPVCTHNMLD DSSDPILTTI RRIGLFNSSA DRVKVIFHPE FLSSTSPLLP VDYEEFVRGC HLGVFPSYYE PWGYTPAECT VMGIPSISTN LSGFGCFMEE HIADPSAYGI YILDRRFRSL DDSCSQLTSF LYSFCQQSRR QRIIQRNRTE RLSDLLDWKY LGRYYMSARH MALSKAFPEH FTYEPNEADA AQGYRYPRPA SVPPSPSLSR HSSPHQSEDE EDPRNGPLEE DGERYDEDEE AAKDRRNIRA PEWPRRASCT SSTSGSKRNS VDTATSSSLS TPSEPLSPTS SLGEERN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.