Details for: A1CF

Gene ID: 29974

Symbol: A1CF

Ensembl ID: ENSG00000148584

Description: APOBEC1 complementation factor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 7.6379
    Cell Significance Index: 128.6600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 6.6615
    Cell Significance Index: -4.4700
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 4.9558
    Cell Significance Index: 37.5800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 3.6195
    Cell Significance Index: 718.3100
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 3.4457
    Cell Significance Index: 34.7600
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 3.2486
    Cell Significance Index: 12.2400
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 3.0327
    Cell Significance Index: 8.0000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.6830
    Cell Significance Index: 121.6100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 2.5745
    Cell Significance Index: 74.1800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 2.4115
    Cell Significance Index: -6.4600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 2.2895
    Cell Significance Index: 137.4500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.9132
    Cell Significance Index: 41.4500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.8930
    Cell Significance Index: 220.6100
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.8505
    Cell Significance Index: 201.2800
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.4849
    Cell Significance Index: 22.2500
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.4283
    Cell Significance Index: 8.2300
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 1.2353
    Cell Significance Index: 13.3900
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.1242
    Cell Significance Index: 27.2300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.9527
    Cell Significance Index: 20.2900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.8591
    Cell Significance Index: 12.6800
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.7642
    Cell Significance Index: 7.5400
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.5299
    Cell Significance Index: 4.2900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.4856
    Cell Significance Index: 17.0700
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.4440
    Cell Significance Index: 3.5500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4029
    Cell Significance Index: 39.8600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.3534
    Cell Significance Index: 11.3200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3474
    Cell Significance Index: 66.1100
  • Cell Name: colonocyte (CL1000347)
    Fold Change: 0.1165
    Cell Significance Index: 0.7200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0882
    Cell Significance Index: 14.3500
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.0842
    Cell Significance Index: 9.6100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0776
    Cell Significance Index: 13.2500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 0.0657
    Cell Significance Index: 1.6900
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.0654
    Cell Significance Index: 0.5000
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0565
    Cell Significance Index: 0.5900
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.0515
    Cell Significance Index: 0.4900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0221
    Cell Significance Index: 1.3900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0162
    Cell Significance Index: 4.6600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0071
    Cell Significance Index: 10.9000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0065
    Cell Significance Index: 1.3100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.0049
    Cell Significance Index: 4.4100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0047
    Cell Significance Index: 6.3500
  • Cell Name: stem cell (CL0000034)
    Fold Change: 0.0041
    Cell Significance Index: 0.0300
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0037
    Cell Significance Index: 2.5700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0021
    Cell Significance Index: 3.8700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.0020
    Cell Significance Index: 1.4500
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 0.0016
    Cell Significance Index: 0.0100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: 0.0009
    Cell Significance Index: 0.1800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0003
    Cell Significance Index: 0.6400
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0003
    Cell Significance Index: -0.1700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0017
    Cell Significance Index: -0.9400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0049
    Cell Significance Index: -1.7400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0056
    Cell Significance Index: -3.0500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0073
    Cell Significance Index: -5.3500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0075
    Cell Significance Index: -0.8600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0084
    Cell Significance Index: -0.1200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0086
    Cell Significance Index: -5.4600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0090
    Cell Significance Index: -4.0700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0107
    Cell Significance Index: -0.8200
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0139
    Cell Significance Index: -0.2100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0223
    Cell Significance Index: -3.0600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0270
    Cell Significance Index: -2.8100
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0285
    Cell Significance Index: -5.1300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0337
    Cell Significance Index: -4.9000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0344
    Cell Significance Index: -1.5200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0357
    Cell Significance Index: -2.1900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0367
    Cell Significance Index: -3.7500
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0369
    Cell Significance Index: -1.6100
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0384
    Cell Significance Index: -1.5700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0402
    Cell Significance Index: -2.7100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0418
    Cell Significance Index: -5.1500
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0427
    Cell Significance Index: -1.3500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0433
    Cell Significance Index: -1.6400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0448
    Cell Significance Index: -2.2600
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0455
    Cell Significance Index: -0.4800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0455
    Cell Significance Index: -3.6100
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0471
    Cell Significance Index: -1.1500
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0493
    Cell Significance Index: -0.8300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0495
    Cell Significance Index: -1.3800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0577
    Cell Significance Index: -1.5500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0593
    Cell Significance Index: -3.0800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0594
    Cell Significance Index: -2.7700
  • Cell Name: goblet cell (CL0000160)
    Fold Change: -0.0652
    Cell Significance Index: -0.5900
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.0668
    Cell Significance Index: -1.1000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0670
    Cell Significance Index: -3.7600
  • Cell Name: pancreatic epsilon cell (CL0005019)
    Fold Change: -0.0680
    Cell Significance Index: -0.6300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0705
    Cell Significance Index: -2.4700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0709
    Cell Significance Index: -4.3600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0764
    Cell Significance Index: -2.5000
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0833
    Cell Significance Index: -1.1600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0854
    Cell Significance Index: -2.7200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0862
    Cell Significance Index: -2.5400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0872
    Cell Significance Index: -2.1800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0904
    Cell Significance Index: -2.4600
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: -0.1016
    Cell Significance Index: -1.6400
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1035
    Cell Significance Index: -1.2900
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: -0.1037
    Cell Significance Index: -0.7300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1044
    Cell Significance Index: -2.6100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1088
    Cell Significance Index: -1.8700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1138
    Cell Significance Index: -1.6800
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1144
    Cell Significance Index: -3.2700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The A1CF gene is a single-codon gene that encodes a protein with a molecular weight of approximately 30 kDa. The protein has a high degree of structural similarity to other APOBEC1 proteins, which are known to be involved in the editing of cytidine to uridine conversions in mRNA. The A1CF protein is highly conserved across species, suggesting that it plays a critical role in the evolution of RNA editing mechanisms. The gene is also highly expressed in several cell types, including retinal cells, hepatocytes, and enteroendocrine cells, which are involved in various metabolic and regulatory processes. **Pathways and Functions** The A1CF gene is involved in several key pathways, including: 1. **Apolipoprotein b mRNA editing enzyme complex**: A1CF is a component of the apolipoprotein b mRNA editing enzyme complex, which is responsible for the editing of cytidine to uridine conversions in mRNA. 2. **Cytidine to uridine editing**: A1CF is involved in the editing of cytidine to uridine conversions in mRNA, which is essential for the proper functioning of various cellular processes. 3. **RNA binding**: A1CF binds to RNA, facilitating the assembly of the editosome and the editing of cytidine to uridine conversions. 4. **Double-stranded RNA binding**: A1CF binds to double-stranded RNA, which is involved in the regulation of gene expression and the modulation of RNA editing. 5. **Endoplasmic reticulum**: A1CF is involved in the regulation of gene expression in the endoplasmic reticulum, which is a critical organelle involved in protein synthesis and modification. The A1CF gene plays a critical role in various cellular processes, including: 1. **DNA demethylation**: A1CF is involved in the regulation of DNA demethylation, which is essential for the proper functioning of various cellular processes. 2. **Nonsense-mediated decay**: A1CF is involved in the regulation of nonsense-mediated decay, which is a process that degrades aberrant mRNAs. 3. **Negative regulation of nuclear-transcribed mRNA catabolic process**: A1CF is involved in the regulation of the nuclear-transcribed mRNA catabolic process, which is essential for the proper functioning of various cellular processes. **Clinical Significance** The A1CF gene has been implicated in various diseases, including: 1. **Retinal diseases**: Mutations in the A1CF gene have been associated with retinal diseases, including retinitis pigmentosa and age-related macular degeneration. 2. **Hepatocellular carcinoma**: A1CF has been implicated in the development of hepatocellular carcinoma, a type of liver cancer. 3. **Enteroendocrine tumors**: A1CF has been implicated in the development of enteroendocrine tumors, which are tumors that arise from the enteroendocrine cells of the pancreas and small intestine. Overall, the A1CF gene plays a critical role in the post-transcriptional regulation of gene expression and has been implicated in various diseases. Further research is needed to fully understand the role of the A1CF gene in human disease.

Genular Protein ID: 4114501141

Symbol: A1CF_HUMAN

Name: APOBEC1 complementation factor

UniProtKB Accession Codes:

Q9NQ94 A1L4F2 A8K7G7 B7ZM14 Q5SZQ0 Q9NQ93 Q9NQX8 Q9NQX9 Q9NXC9 Q9NZD3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 4 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 6 EvolutionaryTrace 1 ExpressionAtlas 1 GO 17 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 RNAct 1 Reactome 2 RefSeq 9 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10781591

Title: Purification and molecular cloning of a novel essential component of the apolipoprotein B mRNA editing enzyme-complex.

PubMed ID: 10781591

DOI: 10.1074/jbc.m001786200

PubMed ID: 10669759

Title: Molecular cloning of APOBEC-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA.

PubMed ID: 10669759

DOI: 10.1128/mcb.20.5.1846-1854.2000

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11134005

Title: Identification of GRY-RBP as an apolipoprotein B RNA-binding protein that interacts with both apobec-1 and apobec-1 complementation factor to modulate C to U editing.

PubMed ID: 11134005

DOI: 10.1074/jbc.m006435200

PubMed ID: 11577082

Title: Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor.

PubMed ID: 11577082

DOI: 10.1074/jbc.m104911200

PubMed ID: 11718896

Title: Isolation, characterization and developmental regulation of the human apobec-1 complementation factor (ACF) gene.

PubMed ID: 11718896

DOI: 10.1016/s0167-4781(01)00295-0

PubMed ID: 11871661

Title: Identification of domains in apobec-1 complementation factor required for RNA binding and apolipoprotein-B mRNA editing.

PubMed ID: 11871661

DOI: 10.1017/s1355838202015649

PubMed ID: 12881431

Title: The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay.

PubMed ID: 12881431

DOI: 10.1093/emboj/cdg369

PubMed ID: 12896982

Title: A novel nuclear localization signal in the auxiliary domain of apobec-1 complementation factor regulates nucleocytoplasmic import and shuttling.

PubMed ID: 12896982

DOI: 10.1074/jbc.m302951200

PubMed ID: 24916387

Title: C to U RNA editing mediated by APOBEC1 requires RNA-binding protein RBM47.

PubMed ID: 24916387

DOI: 10.15252/embr.201438450

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 594
  • Mass: 65202
  • Checksum: AA5EF76BD8815807
  • Sequence:
    • MESNHKSGDG LSGTQKEAAL RALVQRTGYS LVQENGQRKY GGPPPGWDAA PPERGCEIFI 
GKLPRDLFED ELIPLCEKIG KIYEMRMMMD FNGNNRGYAF VTFSNKVEAK NAIKQLNNYE 
IRNGRLLGVC ASVDNCRLFV GGIPKTKKRE EILSEMKKVT EGVVDVIVYP SAADKTKNRG 
FAFVEYESHR AAAMARRKLL PGRIQLWGHG IAVDWAEPEV EVDEDTMSSV KILYVRNLML 
STSEEMIEKE FNNIKPGAVE RVKKIRDYAF VHFSNREDAV EAMKALNGKV LDGSPIEVTL 
AKPVDKDSYV RYTRGTGGRG TMLQGEYTYS LGQVYDPTTT YLGAPVFYAP QTYAAIPSLH 
FPATKGHLSN RAIIRAPSVR EIYMNVPVGA AGVRGLGGRG YLAYTGLGRG YQVKGDKRED 
KLYDILPGME LTPMNPVTLK PQGIKLAPQI LEEICQKNNW GQPVYQLHSA IGQDQRQLFL 
YKITIPALAS QNPAIHPFTP PKLSAFVDEA KTYAAEYTLQ TLGIPTDGGD GTMATAAAAA 
TAFPGYAVPN ATAPVSAAQL KQAVTLGQDL AAYTTYEVYP TFAVTARGDG YGTF

Genular Protein ID: 1362643794

Symbol: B4E1E3_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E1E3

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 4 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 2 InterPro 6 KEGG 1 NCBI Taxonomy 1 NCBIfam 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 2 RefSeq 2 SMART 1 SUPFAM 2

Sequence Information:

  • Length: 587
  • Mass: 64453
  • Checksum: FAB6C3ABA54CD26A
  • Sequence:
    • MSTAIPGLKK GNNALQSIIL QTLLEKENGQ RKYGGPPPGW DAAPPERGCE IFIGKLPRDL 
FEDELIPLCE KIGKIYEMRM MMDFNGNNRG YAFVTFSNKV EAKNAIKQLN NYEIRNGRLL 
GVCASVDNCR LFVGGIPKTK KREEILSEMK KVTEGVVDVI VYPSAADKTK NRGFAFVEYE 
SHRAAAMARR KLLPGRIQLW GHGIAVDWAE PEVEVDEDTM SSVKILYVRN LMLSTSEEMI 
EKEFNNIKPG AVERVKKIRD YAFVHFSNRE DAVEAMKALN GKVLDGSPIE VTLAKPVDKD 
SYVRYTRGTG GRGTMLQGEY TYSLGQVYDP TTTYLGAPVF YAPQTYAAIP SLHFPATKGH 
LSNRAIIRAP SVREIYMNVP VGAAGVRGLG GRGYLAYTGL GRGYQVKGDK REDKLYDILP 
GMELTPMNPV TLKPQGIKLA PQILEEICQK NNWGQPVYQL HSAIGQDQRQ LFLYEITIPA 
LASQNPAIHP FTPPKLSAFV DEAKTYAAEY TLQTLGIPTD GGDGTMATAA AAATAFPGYA 
VPNATAPVSA AQLKQAVTLG QDLAAYTTYE VYPTFAVTAR GDGYGTF

Genular Protein ID: 3807097321

Symbol: F8W9F8_HUMAN

Name: N/A

UniProtKB Accession Codes:

F8W9F8

Database IDs:

ARBA 2 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 4 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 3 Gene3D 2 GeneTree 1 HGNC 1 InterPro 6 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OrthoDB 1 PANTHER 2 PROSITE 2 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 2 RefSeq 2 SMART 1 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 602
  • Mass: 65971
  • Checksum: EF5B389E70154C87
  • Sequence:
    • MEAVCLGTCP EPEASMSTAI PGLKKGNNAL QSIILQTLLE KENGQRKYGG PPPGWDAAPP 
ERGCEIFIGK LPRDLFEDEL IPLCEKIGKI YEMRMMMDFN GNNRGYAFVT FSNKVEAKNA 
IKQLNNYEIR NGRLLGVCAS VDNCRLFVGG IPKTKKREEI LSEMKKVTEG VVDVIVYPSA 
ADKTKNRGFA FVEYESHRAA AMARRKLLPG RIQLWGHGIA VDWAEPEVEV DEDTMSSVKI 
LYVRNLMLST SEEMIEKEFN NIKPGAVERV KKIRDYAFVH FSNREDAVEA MKALNGKVLD 
GSPIEVTLAK PVDKDSYVRY TRGTGGRGTM LQGEYTYSLG QVYDPTTTYL GAPVFYAPQT 
YAAIPSLHFP ATKGHLSNRA IIRAPSVREI YMNVPVGAAG VRGLGGRGYL AYTGLGRGYQ 
VKGDKREDKL YDILPGMELT PMNPVTLKPQ GIKLAPQILE EICQKNNWGQ PVYQLHSAIG 
QDQRQLFLYK ITIPALASQN PAIHPFTPPK LSAFVDEAKT YAAEYTLQTL GIPTDGGDGT 
MATAAAAATA FPGYAVPNAT APVSAAQLKQ AVTLGQDLAA YTTYEVYPTF AVTARGDGYG 
TF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.