Details for: HAS3
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 24.4302
Cell Significance Index: -3.8000 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 15.0211
Cell Significance Index: -3.8100 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 8.6415
Cell Significance Index: 25.7000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 5.5635
Cell Significance Index: 289.0100 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 3.0982
Cell Significance Index: -3.8200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 1.5202
Cell Significance Index: 43.8000 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 1.3944
Cell Significance Index: 85.4900 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 1.3605
Cell Significance Index: 8.4200 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 1.3468
Cell Significance Index: 14.3100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.5935
Cell Significance Index: 12.6400 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: 0.5753
Cell Significance Index: 5.0300 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 0.5750
Cell Significance Index: 15.6500 - Cell Name: granule cell (CL0000120)
Fold Change: 0.5073
Cell Significance Index: 5.7800 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: 0.4952
Cell Significance Index: 4.2600 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.4312
Cell Significance Index: 19.5500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.4306
Cell Significance Index: 81.9500 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 0.4269
Cell Significance Index: 9.1300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.3931
Cell Significance Index: 70.8700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.3725
Cell Significance Index: 36.8500 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 0.3537
Cell Significance Index: 5.3000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.3451
Cell Significance Index: 20.7200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.3443
Cell Significance Index: 42.3300 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.2949
Cell Significance Index: 8.2400 - Cell Name: stellate neuron (CL0000122)
Fold Change: 0.2862
Cell Significance Index: 3.2500 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: 0.2861
Cell Significance Index: 2.6400 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.2783
Cell Significance Index: 6.0300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.2661
Cell Significance Index: 9.3500 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2412
Cell Significance Index: 26.2400 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.2019
Cell Significance Index: 4.4200 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.1759
Cell Significance Index: 2.4000 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1746
Cell Significance Index: 28.4100 - Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 0.1567
Cell Significance Index: 1.7400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.1488
Cell Significance Index: 65.7900 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.1395
Cell Significance Index: 2.0300 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.1387
Cell Significance Index: 125.2500 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.1202
Cell Significance Index: 2.0600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0996
Cell Significance Index: 6.8900 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0551
Cell Significance Index: 3.4700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0516
Cell Significance Index: 10.2500 - Cell Name: keratinocyte (CL0000312)
Fold Change: 0.0316
Cell Significance Index: 0.7900 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.0308
Cell Significance Index: 16.8300 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0272
Cell Significance Index: 5.4500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 0.0175
Cell Significance Index: 0.5600 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: 0.0159
Cell Significance Index: 12.0200 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0108
Cell Significance Index: 0.2700 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.0096
Cell Significance Index: 0.5000 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0078
Cell Significance Index: 1.1400 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0072
Cell Significance Index: 2.5700 - Cell Name: lactocyte (CL0002325)
Fold Change: 0.0022
Cell Significance Index: 0.2900 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.0020
Cell Significance Index: 0.0300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0002
Cell Significance Index: -0.3000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0010
Cell Significance Index: -1.6000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0018
Cell Significance Index: -3.3900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0033
Cell Significance Index: -4.4900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0034
Cell Significance Index: -2.1500 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0035
Cell Significance Index: -0.2500 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0046
Cell Significance Index: -3.3700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0056
Cell Significance Index: -4.1600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0068
Cell Significance Index: -3.8600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0085
Cell Significance Index: -3.8700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0109
Cell Significance Index: -3.1500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0119
Cell Significance Index: -1.3900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0122
Cell Significance Index: -0.1800 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0140
Cell Significance Index: -1.7900 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0154
Cell Significance Index: -2.6300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0181
Cell Significance Index: -1.8500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0187
Cell Significance Index: -2.1400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0201
Cell Significance Index: -0.9500 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0256
Cell Significance Index: -3.5100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0276
Cell Significance Index: -5.8200 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0307
Cell Significance Index: -0.8200 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0314
Cell Significance Index: -3.7000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0368
Cell Significance Index: -3.8300 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0393
Cell Significance Index: -2.9300 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0394
Cell Significance Index: -2.6500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0432
Cell Significance Index: -2.4300 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: -0.0445
Cell Significance Index: -0.2900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0468
Cell Significance Index: -3.6000 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0468
Cell Significance Index: -0.9700 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0499
Cell Significance Index: -3.0700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0523
Cell Significance Index: -2.4400 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0577
Cell Significance Index: -3.7200 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0662
Cell Significance Index: -2.9300 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.0663
Cell Significance Index: -0.9300 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0672
Cell Significance Index: -1.8000 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0752
Cell Significance Index: -2.7600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0781
Cell Significance Index: -4.1000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0804
Cell Significance Index: -3.0500 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.0814
Cell Significance Index: -2.1400 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0833
Cell Significance Index: -2.1400 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0853
Cell Significance Index: -1.8100 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0863
Cell Significance Index: -4.3600 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0867
Cell Significance Index: -2.7600 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0945
Cell Significance Index: -3.3100 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0964
Cell Significance Index: -3.3500 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0964
Cell Significance Index: -3.1600 - Cell Name: proerythroblast (CL0000547)
Fold Change: -0.1001
Cell Significance Index: -1.4400 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.1020
Cell Significance Index: -1.5100 - Cell Name: pulmonary alveolar type 2 cell (CL0002063)
Fold Change: -0.1040
Cell Significance Index: -0.8600 - Cell Name: mucous neck cell (CL0000651)
Fold Change: -0.1050
Cell Significance Index: -0.5000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 4257301785
Symbol: HYAS3_HUMAN
Name: Hyaluronan synthase 3
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15616553
Title: The sequence and analysis of duplication-rich human chromosome 16.
PubMed ID: 15616553
DOI: 10.1038/nature03187
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9083017
Title: Molecular cloning and characterization of a cDNA encoding the third putative mammalian hyaluronan synthase.
PubMed ID: 9083017
PubMed ID: 23303191
Title: Hyaluronan synthase 1 (HAS1) requires higher cellular UDP-GlcNAc concentration than HAS2 and HAS3.
PubMed ID: 23303191
PubMed ID: 25795779
Title: Fluorescence resonance energy transfer (FRET) and proximity ligation assays reveal functionally relevant homo- and heteromeric complexes among hyaluronan synthases HAS1, HAS2, and HAS3.
PubMed ID: 25795779
PubMed ID: 26883802
Title: UDP-sugar substrates of HAS3 regulate its O-GlcNAcylation, intracellular traffic, extracellular shedding and correlate with melanoma progression.
PubMed ID: 26883802
PubMed ID: 30394292
Title: Effects of mutations in the post-translational modification sites on the trafficking of hyaluronan synthase 2 (HAS2).
PubMed ID: 30394292
Sequence Information:
- Length: 553
- Mass: 62998
- Checksum: 82F3B0C932EE9EA3
- Sequence:
MPVQLTTALR VVGTSLFALA VLGGILAAYV TGYQFIHTEK HYLSFGLYGA ILGLHLLIQS LFAFLEHRRM RRAGQALKLP SPRRGSVALC IAAYQEDPDY LRKCLRSAQR ISFPDLKVVM VVDGNRQEDA YMLDIFHEVL GGTEQAGFFV WRSNFHEAGE GETEASLQEG MDRVRDVVRA STFSCIMQKW GGKREVMYTA FKALGDSVDY IQVCDSDTVL DPACTIEMLR VLEEDPQVGG VGGDVQILNK YDSWISFLSS VRYWMAFNVE RACQSYFGCV QCISGPLGMY RNSLLQQFLE DWYHQKFLGS KCSFGDDRHL TNRVLSLGYR TKYTARSKCL TETPTKYLRW LNQQTRWSKS YFREWLYNSL WFHKHHLWMT YESVVTGFFP FFLIATVIQL FYRGRIWNIL LFLLTVQLVG IIKATYACFL RGNAEMIFMS LYSLLYMSSL LPAKIFAIAT INKSGWGTSG RKTIVVNFIG LIPVSIWVAV LLGGLAYTAY CQDLFSETEL AFLVSGAILY GCYWVALLML YLAIIARRCG KKPEQYSLAF AEV
Genular Protein ID: 3686707703
Symbol: Q96RV2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11431361
Title: Hyaluronan synthase 3 overexpression promotes the growth of TSU prostate cancer cells.
PubMed ID: 11431361
Sequence Information:
- Length: 553
- Mass: 62894
- Checksum: 75D8E2A3F6BD2469
- Sequence:
MPVQLTTALR VVGTSLFALA VLGGILAAYV TGYQFIHTEK HYLSFGLYGA ILGLHLLIQS LFAFLEHRRM QRAGQALKLP SPRRGSVALC IAAYQEDPDY LRKCLRSAQR ISFPDLKVVM VVDGNRQEDA YMLDIFHEVL GGTEQAGFFV WRSNFHEAGE GETEASLQEG MDRVRDVVRA STFSCIMQKW GGKREVMYTA FKALGDSVDY IQVCDSDTVL DPACTIEMLR VLEEDPQVGG VGGDVQILNK YDSWISFLSS VRYWMAFNVE RACQSYFGCV QCISGPLGMY RNSLLQQFLE DWYHQKFLGS KCSFGDDRHL TNRVLSLGYR TKYTARSKCL TETPTKYLRW LNQQTRWSKS YFREWLYNSL WFHKHHLWMT YESVVTGFFP FFLIATVIQL FYRGRIWNIL LFLLTVQLVG IIKATYACFL RGNAEMIFMS LYSLLYMSSL LPAKIFAIAT INKSGWGTSG RKTIVVNFIG LIPVSIWVAV LLGGLAYTAY CQDLFSETEL AFLVSGAILY GCYWVALLML YLAIIARRCG KKPEQSSLAF AEV
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.