Details for: HMOX2

Gene ID: 3163

Symbol: HMOX2

Ensembl ID: ENSG00000103415

Description: heme oxygenase 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 252.4025
    Cell Significance Index: -39.2600
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 137.8904
    Cell Significance Index: -34.9800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 94.6199
    Cell Significance Index: -38.4400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 90.0402
    Cell Significance Index: -42.5100
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 83.1089
    Cell Significance Index: -42.7500
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 40.6916
    Cell Significance Index: -38.8500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 32.1747
    Cell Significance Index: -39.6700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.0759
    Cell Significance Index: -39.7600
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 9.4157
    Cell Significance Index: -28.9200
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 7.3061
    Cell Significance Index: -15.9900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 5.5359
    Cell Significance Index: -14.8300
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 2.3487
    Cell Significance Index: 68.9800
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 2.0060
    Cell Significance Index: 16.8500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.4093
    Cell Significance Index: 84.6100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.9952
    Cell Significance Index: 52.2500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.9611
    Cell Significance Index: 73.7500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.8674
    Cell Significance Index: 174.0000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.8522
    Cell Significance Index: 109.2500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.7266
    Cell Significance Index: 130.9800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6696
    Cell Significance Index: 108.9100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.6597
    Cell Significance Index: 31.0100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.6440
    Cell Significance Index: 351.7000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6087
    Cell Significance Index: 42.1000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.5923
    Cell Significance Index: 72.8300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.5353
    Cell Significance Index: 69.1600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.5130
    Cell Significance Index: 26.6500
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.5078
    Cell Significance Index: 7.5000
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.4695
    Cell Significance Index: 207.5600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4691
    Cell Significance Index: 21.8700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4482
    Cell Significance Index: 44.3400
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.4455
    Cell Significance Index: 33.2100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.4427
    Cell Significance Index: 9.5900
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 0.4335
    Cell Significance Index: 6.4000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4187
    Cell Significance Index: 83.0900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4098
    Cell Significance Index: 56.2800
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.3798
    Cell Significance Index: 26.8600
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.3657
    Cell Significance Index: 4.9900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3417
    Cell Significance Index: 122.5800
  • Cell Name: germ cell (CL0000586)
    Fold Change: 0.3020
    Cell Significance Index: 2.2800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.2779
    Cell Significance Index: 192.2000
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.2275
    Cell Significance Index: 14.6800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2070
    Cell Significance Index: 5.9700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1487
    Cell Significance Index: 28.3000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1377
    Cell Significance Index: 6.2400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1315
    Cell Significance Index: 22.4600
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.1267
    Cell Significance Index: 3.4500
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0997
    Cell Significance Index: 11.7600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0884
    Cell Significance Index: 3.9100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0698
    Cell Significance Index: 3.5300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0057
    Cell Significance Index: 0.1600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0005
    Cell Significance Index: -0.3600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0067
    Cell Significance Index: -4.9700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0069
    Cell Significance Index: -13.0500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0119
    Cell Significance Index: -7.4300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0164
    Cell Significance Index: -12.0000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0194
    Cell Significance Index: -0.6800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0198
    Cell Significance Index: -36.5600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0230
    Cell Significance Index: -35.4800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0301
    Cell Significance Index: -17.0000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0308
    Cell Significance Index: -41.8800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0391
    Cell Significance Index: -1.4800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0421
    Cell Significance Index: -26.7200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0508
    Cell Significance Index: -5.1900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.0539
    Cell Significance Index: -3.4000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0672
    Cell Significance Index: -30.5000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0949
    Cell Significance Index: -19.9900
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1150
    Cell Significance Index: -3.0700
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -0.1189
    Cell Significance Index: -1.1000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1208
    Cell Significance Index: -13.8400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1263
    Cell Significance Index: -36.3500
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.1310
    Cell Significance Index: -1.6800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1320
    Cell Significance Index: -3.4700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1344
    Cell Significance Index: -15.6600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1604
    Cell Significance Index: -23.3200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1643
    Cell Significance Index: -2.7500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1739
    Cell Significance Index: -2.9800
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.2250
    Cell Significance Index: -6.0300
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.2604
    Cell Significance Index: -6.5100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.2761
    Cell Significance Index: -5.7800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2873
    Cell Significance Index: -32.7900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.2911
    Cell Significance Index: -9.3300
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.3370
    Cell Significance Index: -8.6100
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.3417
    Cell Significance Index: -9.1400
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3440
    Cell Significance Index: -17.9200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.3644
    Cell Significance Index: -7.7600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3780
    Cell Significance Index: -39.3600
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.3828
    Cell Significance Index: -8.8500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.4357
    Cell Significance Index: -34.5100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.4409
    Cell Significance Index: -24.7400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.5436
    Cell Significance Index: -22.2700
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: -0.5596
    Cell Significance Index: -8.3900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.6141
    Cell Significance Index: -37.6500
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.6667
    Cell Significance Index: -11.2300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.7168
    Cell Significance Index: -25.1100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.7194
    Cell Significance Index: -25.0000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.7328
    Cell Significance Index: -23.3400
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.7433
    Cell Significance Index: -8.8600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.7563
    Cell Significance Index: -24.7600
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.8057
    Cell Significance Index: -14.2400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.8552
    Cell Significance Index: -18.1500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Heme degradation**: HMOX2 is a heme oxygenase, an enzyme that catalyzes the degradation of heme into biliverdin, carbon monoxide, and ferrous iron. 2. **Oxidative stress protection**: The enzyme's activity helps to protect cells against oxidative stress by breaking down heme, a toxic molecule that can cause damage to cellular components. 3. **Widespread expression**: HMOX2 is expressed in various cell types, including immune cells, epithelial cells, and neurons, suggesting its importance in maintaining cellular homeostasis. 4. **Regulation of immune responses**: The enzyme's activity can influence immune responses, particularly in the context of inflammation and oxidative stress. **Pathways and Functions** 1. **Heme catabolic process**: HMOX2 is involved in the breakdown of heme into biliverdin, carbon monoxide, and ferrous iron. 2. **Cytoprotection**: The enzyme's activity helps to protect cells against oxidative stress by breaking down heme. 3. **Immune system regulation**: HMOX2 can influence immune responses, particularly in the context of inflammation and oxidative stress. 4. **Response to hypoxia**: The enzyme's activity can be upregulated in response to hypoxic conditions, suggesting its role in maintaining cellular homeostasis under low oxygen conditions. 5. **Redox regulation**: HMOX2 can regulate redox reactions, influencing the balance between oxidative and reductive processes within the cell. **Clinical Significance** 1. **Oxidative stress disorders**: Alterations in HMOX2 expression or activity have been implicated in various oxidative stress disorders, including neurodegenerative diseases, cancer, and inflammatory conditions. 2. **Immunological disorders**: The enzyme's role in regulating immune responses makes it an important target in the treatment of immunological disorders, such as autoimmune diseases and cancer. 3. **Cardiovascular disease**: HMOX2 has been shown to play a protective role in cardiovascular disease, particularly in the context of oxidative stress and inflammation. 4. **Cancer therapy**: The enzyme's activity can influence cancer progression and treatment outcomes, highlighting its potential as a therapeutic target. 5. **Neurodegenerative diseases**: HMOX2 has been implicated in the pathogenesis of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, suggesting its potential as a therapeutic target. In conclusion, HMOX2 is a critical enzyme involved in maintaining cellular homeostasis and protecting against oxidative stress. Its widespread expression and regulation of immune responses make it an important target for the treatment of various diseases, including oxidative stress disorders, immunological disorders, and neurodegenerative diseases. Further research is needed to fully elucidate the mechanisms underlying HMOX2's functions and to explore its therapeutic potential.

Genular Protein ID: 181133486

Symbol: HMOX2_HUMAN

Name: Heme oxygenase 2

UniProtKB Accession Codes:

P30519 A8MT35 D3DUD5 I3L430 O60605

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEBI 14 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EC 1 EMBL 10 Ensembl 18 EvolutionaryTrace 1 ExpressionAtlas 1 GO 11 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 7 PDBsum 7 PIR 2 PIRSF 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 5 RefSeq 11 Rhea 4 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 7890772

Title: Heme oxygenase-2. Properties of the heme complex of the purified tryptic fragment of recombinant human heme oxygenase-2.

PubMed ID: 7890772

DOI: 10.1074/jbc.270.11.6345

PubMed ID: 1575508

Title: Human heme oxygenase-2: characterization and expression of a full-length cDNA and evidence suggesting that the two HO-2 transcripts may differ by choice of polyadenylation signal.

PubMed ID: 1575508

DOI: 10.1016/0003-9861(92)90481-b

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 38056462

Title: An enzyme that selectively S-nitrosylates proteins to regulate insulin signaling.

PubMed ID: 38056462

DOI: 10.1016/j.cell.2023.11.009

PubMed ID: 17965015

Title: Comparison of apo- and heme-bound crystal structures of a truncated human heme oxygenase-2.

PubMed ID: 17965015

DOI: 10.1074/jbc.m707396200

Sequence Information:

  • Length: 316
  • Mass: 36033
  • Checksum: BF4B6A341F1A81AC
  • Sequence:
    • MSAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAEN TQFVKDFLKG 
NIKKELFKLA TTALYFTYSA LEEEMERNKD HPAFAPLYFP MELHRKEALT KDMEYFFGEN 
WEEQVQCPKA AQKYVERIHY IGQNEPELLV AHAYTRYMGD LSGGQVLKKV AQRALKLPST 
GEGTQFYLFE NVDNAQQFKQ LYRARMNALD LNMKTKERIV EEANKAFEYN MQIFNELDQA 
GSTLARETLE DGFPVHDGKG DMRKCPFYAA EQDKGALEGS SCPFRTAMAV LRKPSLQFIL 
AAGVALAAGL LAWYYM

Genular Protein ID: 185400223

Symbol: B3KSE0_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KSE0

Database IDs:

ARBA 6 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 14 DNASU 1 DisGeNET 1 EC 1 EMBL 2 GO 7 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 1 RefSeq 1 Rhea 3 SAM 2 SUPFAM 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 316
  • Mass: 35961
  • Checksum: 99896A34B53881AD
  • Sequence:
    • MSAEVETSEG VDESEKKNSG ALEKENQMRM ADLSELLKEG TKEAHDRAGN TQFVKDFLKG 
NIKKELFKLA TTALYFTYSA LEEEMERNKD HPAFAPLYFP MELHRKEALT KDMEYFFGEN 
WEEQVQCPKA AQKYVERIHY IGQNEPELLV AHAYTRYMGD LSGGQVLKKV AQRALKLPST 
GEGTQFYLFE NVDNAQQFKQ LYRARMNALD LNMKTKERIV EEANKAFEYN MQIFNELDQA 
GSTLARETLE DGFPVHDGKG DMRKCPFYAA EQDKGALEGS SCPFRTAMAV LRKPSLQFIL 
AAGVALAAGL LAWYYM

Genular Protein ID: 2425497970

Symbol: A0A087WT44_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WT44

Database IDs:

ARBA 7 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 1 Ensembl 3 GO 4 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 2 SAM 2 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15616553

Title: The sequence and analysis of duplication-rich human chromosome 16.

PubMed ID: 15616553

DOI: 10.1038/nature03187

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

Sequence Information:

  • Length: 370
  • Mass: 41669
  • Checksum: A2E0B8443B79108C
  • Sequence:
    • MESRSVAQAG VQWISLAHCS LHLLGSRDSP ASASCVAGIT GPEEREQQEP HPAAMSAEVE 
TSEGVDESEK KNSGALEKEN QMRMADLSEL LKEGTKEAHD RAENTQFVKD FLKGNIKKEL 
FKLATTALYF TYSALEEEME RNKDHPAFAP LYFPMELHRK EALTKDMEYF FGENWEEQVQ 
CPKAAQKYVE RIHYIGQNEP ELLVAHAYTR YMGDLSGGQV LKKVAQRALK LPSTGEGTQF 
YLFENVDNAQ QFKQLYRARM NALDLNMKTK ERIVEEANKA FEYNMQIFNE LDQAGSTLAR 
ETLEDGFPVH DGKGDMRKCP FYAAEQDKGA LEGSSCPFRT AMAVLRKPSL QFILAAGVAL 
AAGLLAWYYM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.