Details for: ITGAM

Gene ID: 3684

Symbol: ITGAM

Ensembl ID: ENSG00000169896

Description: integrin subunit alpha M

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 59.0182
    Cell Significance Index: -9.1800
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 35.0689
    Cell Significance Index: -8.9000
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 24.7873
    Cell Significance Index: -10.0700
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 20.8987
    Cell Significance Index: -10.7500
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 7.4212
    Cell Significance Index: -9.1500
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 4.1922
    Cell Significance Index: 64.8600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 3.9980
    Cell Significance Index: 99.9400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.9974
    Cell Significance Index: 55.4000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 2.9948
    Cell Significance Index: 183.6100
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.5218
    Cell Significance Index: 54.6400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.3758
    Cell Significance Index: -9.3800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 2.1429
    Cell Significance Index: -4.6900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 1.8591
    Cell Significance Index: 15.1600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.7764
    Cell Significance Index: 56.9000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6835
    Cell Significance Index: 67.6100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5420
    Cell Significance Index: 489.4200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.5092
    Cell Significance Index: 10.8500
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 0.4211
    Cell Significance Index: 4.4800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3559
    Cell Significance Index: 57.8900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3457
    Cell Significance Index: 37.6000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.3310
    Cell Significance Index: 9.7200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2335
    Cell Significance Index: 14.0200
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 0.2179
    Cell Significance Index: 1.7700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1264
    Cell Significance Index: 24.0500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0959
    Cell Significance Index: 6.6400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0312
    Cell Significance Index: 6.1900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0031
    Cell Significance Index: 0.6300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0003
    Cell Significance Index: -0.0100
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0017
    Cell Significance Index: -3.2200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0044
    Cell Significance Index: -8.1800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0050
    Cell Significance Index: -7.7500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0051
    Cell Significance Index: -3.5500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0055
    Cell Significance Index: -7.4600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0082
    Cell Significance Index: -1.4700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0103
    Cell Significance Index: -7.8100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0130
    Cell Significance Index: -8.2800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0137
    Cell Significance Index: -10.0100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0148
    Cell Significance Index: -10.9600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0160
    Cell Significance Index: -8.7200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0161
    Cell Significance Index: -5.7700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0161
    Cell Significance Index: -7.1400
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0195
    Cell Significance Index: -1.9900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0197
    Cell Significance Index: -8.9300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0198
    Cell Significance Index: -0.4100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0198
    Cell Significance Index: -11.1500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0210
    Cell Significance Index: -6.0300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0225
    Cell Significance Index: -1.0200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0420
    Cell Significance Index: -6.1100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0528
    Cell Significance Index: -11.1300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0585
    Cell Significance Index: -9.9900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0630
    Cell Significance Index: -8.6500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0641
    Cell Significance Index: -8.2800
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0646
    Cell Significance Index: -4.1700
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.0650
    Cell Significance Index: -0.9500
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0656
    Cell Significance Index: -8.0600
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0657
    Cell Significance Index: -0.9900
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0711
    Cell Significance Index: -9.1200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0774
    Cell Significance Index: -3.6400
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0789
    Cell Significance Index: -9.3000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0795
    Cell Significance Index: -9.2600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0838
    Cell Significance Index: -9.6000
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0862
    Cell Significance Index: -8.9800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0892
    Cell Significance Index: -6.8400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1006
    Cell Significance Index: -2.6900
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1081
    Cell Significance Index: -4.7000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1150
    Cell Significance Index: -7.7300
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.1197
    Cell Significance Index: -1.5900
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: -0.1209
    Cell Significance Index: -1.3200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1319
    Cell Significance Index: -8.1100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1320
    Cell Significance Index: -9.8400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1328
    Cell Significance Index: -3.7100
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.1365
    Cell Significance Index: -1.6400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1460
    Cell Significance Index: -9.2000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1499
    Cell Significance Index: -6.6300
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1505
    Cell Significance Index: -7.8400
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.1555
    Cell Significance Index: -3.0400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1563
    Cell Significance Index: -8.1200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1594
    Cell Significance Index: -4.2700
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1666
    Cell Significance Index: -2.8300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1764
    Cell Significance Index: -9.9000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1789
    Cell Significance Index: -4.5700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1826
    Cell Significance Index: -9.2300
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1831
    Cell Significance Index: -6.9400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1889
    Cell Significance Index: -9.9200
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.1956
    Cell Significance Index: -2.3000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2015
    Cell Significance Index: -7.0600
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.2048
    Cell Significance Index: -2.8800
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.2124
    Cell Significance Index: -1.8000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2136
    Cell Significance Index: -9.9600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2252
    Cell Significance Index: -3.8600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2261
    Cell Significance Index: -7.2000
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.2299
    Cell Significance Index: -5.9100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2370
    Cell Significance Index: -7.7600
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.2454
    Cell Significance Index: -2.5100
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.2595
    Cell Significance Index: -3.2100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2600
    Cell Significance Index: -9.5500
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.2722
    Cell Significance Index: -8.6100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2749
    Cell Significance Index: -7.3400
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.2758
    Cell Significance Index: -2.4300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cell Surface Expression:** ITGAM is predominantly expressed on the surface of immune cells, including classical monocytes, macrophages, and microglial cells. 2. **Integrin Function:** ITGAM forms heterodimers with beta subunits to form functional integrins, which mediate cell-cell and cell-matrix adhesion. 3. **Signaling Pathways:** ITGAM is involved in various signaling pathways, including integrin-mediated signaling, cytokine signaling, and complement-mediated signaling. 4. **Expression in Specific Cells:** ITGAM is highly expressed in myelocytes, CD14-positive monocytes, lung macrophages, and central nervous system macrophages. **Pathways and Functions:** 1. **Cell-Cell Adhesion:** ITGAM mediates cell-cell adhesion via plasma-membrane adhesion molecules, which is essential for the organization of immune cells in tissues. 2. **Phagocytosis:** ITGAM is involved in phagocytosis, a critical function of immune cells, including classical monocytes and macrophages. 3. **Cytokine Signaling:** ITGAM is involved in cytokine signaling, including interleukin-4 and interleukin-13 signaling, which regulates immune responses. 4. **Complement-Mediated Signaling:** ITGAM is involved in complement-mediated signaling, including complement component C3b binding, which is essential for immune response regulation. 5. **Immune Response Regulation:** ITGAM regulates immune responses, including innate immune response, innate immune system, and adaptive immune response. **Clinical Significance:** 1. **Autoimmune Diseases:** ITGAM is associated with autoimmune diseases, including multiple sclerosis, rheumatoid arthritis, and lupus, where its dysfunction leads to immune system dysregulation. 2. **Infectious Diseases:** ITGAM plays a crucial role in the regulation of immune responses to pathogens, including bacteria and viruses. 3. **Cancer:** ITGAM is involved in cancer progression, including metastasis and immune evasion. 4. **Neurological Disorders:** ITGAM is involved in neurological disorders, including Alzheimer's disease, Parkinson's disease, and multiple sclerosis. In conclusion, ITGAM is a crucial component of the immune system, and its dysfunction leads to various diseases. Further research is necessary to fully understand the mechanisms of ITGAM in immune regulation and disease.

Genular Protein ID: 286483829

Symbol: ITAM_HUMAN

Name: Integrin alpha-M

UniProtKB Accession Codes:

P11215 Q4VAK0 Q4VAK1 Q4VAK2

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CORUM 1 CPTC 1 CTD 1 ChEBI 11 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 39 EMDB 2 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 44 Gene3D 5 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 24 PDBsum 24 PIR 1 PRIDE 1 PRINTS 2 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 5 RefSeq 2 SASBDB 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2457584

Title: The human leukocyte adhesion glycoprotein Mac-1 (complement receptor type 3, CD11b) alpha subunit. Cloning, primary structure, and relation to the integrins, von Willebrand factor and factor B.

PubMed ID: 2457584

DOI: 10.1016/s0021-9258(18)37770-6

PubMed ID: 2833753

Title: Molecular cloning of the alpha subunit of human and guinea pig leukocyte adhesion glycoprotein Mo1: chromosomal localization and homology to the alpha subunits of integrins.

PubMed ID: 2833753

DOI: 10.1073/pnas.85.8.2776

PubMed ID: 2454931

Title: Amino acid sequence of the alpha subunit of human leukocyte adhesion receptor Mo1 (complement receptor type 3).

PubMed ID: 2454931

DOI: 10.1083/jcb.106.6.2153

PubMed ID: 8419480

Title: Structural analysis of the CD11b gene and phylogenetic analysis of the alpha-integrin gene family demonstrate remarkable conservation of genomic organization and suggest early diversification during evolution.

PubMed ID: 8419480

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2563162

Title: cDNA sequence for the alpha M subunit of the human neutrophil adherence receptor indicates homology to integrin alpha subunits.

PubMed ID: 2563162

DOI: 10.1073/pnas.86.1.257

PubMed ID: 1683702

Title: The promoter of the CD11b gene directs myeloid-specific and developmentally regulated expression.

PubMed ID: 1683702

DOI: 10.1073/pnas.88.23.10525

PubMed ID: 1346576

Title: Characterization of the myeloid-specific CD11b promoter.

PubMed ID: 1346576

PubMed ID: 3539202

Title: N-terminal sequence of human leukocyte glycoprotein Mo1: conservation across species and homology to platelet IIb/IIIa.

PubMed ID: 3539202

DOI: 10.1016/0167-4838(86)90037-3

PubMed ID: 9558116

Title: Human polymorphonuclear leukocytes adhere to complement factor H through an interaction that involves alphaMbeta2 (CD11b/CD18).

PubMed ID: 9558116

PubMed ID: 12208882

Title: The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1.

PubMed ID: 12208882

DOI: 10.1084/jem.20020267

PubMed ID: 15194813

Title: JAM-C is a component of desmosomes and a ligand for CD11b/CD18-mediated neutrophil transepithelial migration.

PubMed ID: 15194813

DOI: 10.1091/mbc.e04-04-0317

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 20008295

Title: Factor H and factor H-related protein 1 bind to human neutrophils via complement receptor 3, mediate attachment to Candida albicans, and enhance neutrophil antimicrobial activity.

PubMed ID: 20008295

DOI: 10.4049/jimmunol.0901702

PubMed ID: 21193407

Title: Complement receptor Mac-1 is an adaptor for NB1 (CD177)-mediated PR3-ANCA neutrophil activation.

PubMed ID: 21193407

DOI: 10.1074/jbc.m110.171256

PubMed ID: 27055590

Title: LFA-1 and Mac-1 integrins bind to the serine/threonine-rich domain of thrombomodulin.

PubMed ID: 27055590

DOI: 10.1016/j.bbrc.2016.04.007

PubMed ID: 28807980

Title: CD177 modulates human neutrophil migration through activation-mediated integrin and chemoreceptor regulation.

PubMed ID: 28807980

DOI: 10.1182/blood-2017-03-768507

PubMed ID: 38730209

Title: Deletion of Tmem268 in mice suppresses anti-infectious immune responses by downregulating CD11b signaling.

PubMed ID: 38730209

DOI: 10.1038/s44319-024-00141-6

PubMed ID: 7867070

Title: Crystal structure of the A domain from the alpha subunit of integrin CR3 (CD11b/CD18).

PubMed ID: 7867070

DOI: 10.1016/0092-8674(95)90517-0

PubMed ID: 8747460

Title: Two conformations of the integrin A-domain (I-domain): a pathway for activation?

PubMed ID: 8747460

DOI: 10.1016/s0969-2126(01)00271-4

PubMed ID: 9687375

Title: Cation binding to the integrin CD11b I domain and activation model assessment.

PubMed ID: 9687375

DOI: 10.1016/s0969-2126(98)00093-8

PubMed ID: 9560195

Title: Experimental support for a beta-propeller domain in integrin alpha-subunits and a calcium binding site on its lower surface.

PubMed ID: 9560195

DOI: 10.1073/pnas.95.9.4870

PubMed ID: 18204448

Title: A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus.

PubMed ID: 18204448

DOI: 10.1038/ng.71

PubMed ID: 18204446

Title: Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

PubMed ID: 18204446

DOI: 10.1038/ng.81

Sequence Information:

  • Length: 1152
  • Mass: 127179
  • Checksum: DF77408ED5EE25F9
  • Sequence:
    • MALRVLLLTA LTLCHGFNLD TENAMTFQEN ARGFGQSVVQ LQGSRVVVGA PQEIVAANQR 
GSLYQCDYST GSCEPIRLQV PVEAVNMSLG LSLAATTSPP QLLACGPTVH QTCSENTYVK 
GLCFLFGSNL RQQPQKFPEA LRGCPQEDSD IAFLIDGSGS IIPHDFRRMK EFVSTVMEQL 
KKSKTLFSLM QYSEEFRIHF TFKEFQNNPN PRSLVKPITQ LLGRTHTATG IRKVVRELFN 
ITNGARKNAF KILVVITDGE KFGDPLGYED VIPEADREGV IRYVIGVGDA FRSEKSRQEL 
NTIASKPPRD HVFQVNNFEA LKTIQNQLRE KIFAIEGTQT GSSSSFEHEM SQEGFSAAIT 
SNGPLLSTVG SYDWAGGVFL YTSKEKSTFI NMTRVDSDMN DAYLGYAAAI ILRNRVQSLV 
LGAPRYQHIG LVAMFRQNTG MWESNANVKG TQIGAYFGAS LCSVDVDSNG STDLVLIGAP 
HYYEQTRGGQ VSVCPLPRGR ARWQCDAVLY GEQGQPWGRF GAALTVLGDV NGDKLTDVAI 
GAPGEEDNRG AVYLFHGTSG SGISPSHSQR IAGSKLSPRL QYFGQSLSGG QDLTMDGLVD 
LTVGAQGHVL LLRSQPVLRV KAIMEFNPRE VARNVFECND QVVKGKEAGE VRVCLHVQKS 
TRDRLREGQI QSVVTYDLAL DSGRPHSRAV FNETKNSTRR QTQVLGLTQT CETLKLQLPN 
CIEDPVSPIV LRLNFSLVGT PLSAFGNLRP VLAEDAQRLF TALFPFEKNC GNDNICQDDL 
SITFSFMSLD CLVVGGPREF NVTVTVRNDG EDSYRTQVTF FFPLDLSYRK VSTLQNQRSQ 
RSWRLACESA SSTEVSGALK STSCSINHPI FPENSEVTFN ITFDVDSKAS LGNKLLLKAN 
VTSENNMPRT NKTEFQLELP VKYAVYMVVT SHGVSTKYLN FTASENTSRV MQHQYQVSNL 
GQRSLPISLV FLVPVRLNQT VIWDRPQVTF SENLSSTCHT KERLPSHSDF LAELRKAPVV 
NCSIAVCQRI QCDIPFFGIQ EEFNATLKGN LSFDWYIKTS HNHLLIVSTA EILFNDSVFT 
LLPGQGAFVR SQTETKVEPF EVPNPLPLIV GSSVGGLLLL ALITAALYKL GFFKRQYKDM 
MSEGGPPGAE PQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.