Details for: ITGB6

Gene ID: 3694

Symbol: ITGB6

Ensembl ID: ENSG00000115221

Description: integrin subunit beta 6

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 3.97
    Marker Score: 3937
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: 3.96
    Marker Score: 2249
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 2.16
    Marker Score: 2446
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 2.11
    Marker Score: 33877
  • Cell Name: type II pneumocyte (CL0002063)
    Fold Change: 2.07
    Marker Score: 13495
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 2.05
    Marker Score: 1082
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 1.92
    Marker Score: 3078
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.86
    Marker Score: 2734
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.84
    Marker Score: 3494
  • Cell Name: type I pneumocyte (CL0002062)
    Fold Change: 1.83
    Marker Score: 2210
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: 1.79
    Marker Score: 3167
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 1.59
    Marker Score: 663
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 1.53
    Marker Score: 1161
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.47
    Marker Score: 1021
  • Cell Name: epithelial cell of lung (CL0000082)
    Fold Change: 1.44
    Marker Score: 7594
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 1.42
    Marker Score: 639
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 1.42
    Marker Score: 1120
  • Cell Name: papillary tips cell (CL1000597)
    Fold Change: 1.42
    Marker Score: 286
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 1.4
    Marker Score: 3422
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 1.32
    Marker Score: 3534
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.28
    Marker Score: 2596
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 1.25
    Marker Score: 1770
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 1.25
    Marker Score: 390
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.23
    Marker Score: 2907
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.23
    Marker Score: 19204
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.14
    Marker Score: 1013
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 1.07
    Marker Score: 1090
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.01
    Marker Score: 1061
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71800.5
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48026
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1
    Marker Score: 3837
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30406
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.98
    Marker Score: 505
  • Cell Name: malignant cell (CL0001064)
    Fold Change: 0.98
    Marker Score: 13130
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 459
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2411
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2734
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: 0.91
    Marker Score: 979.5
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 0.91
    Marker Score: 1656
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.91
    Marker Score: 5165
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 324
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 0.89
    Marker Score: 5676
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5285
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.84
    Marker Score: 507
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.82
    Marker Score: 330
  • Cell Name: myoepithelial cell of mammary gland (CL0002324)
    Fold Change: 0.82
    Marker Score: 4017
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.81
    Marker Score: 262
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1269
  • Cell Name: mammary gland epithelial cell (CL0002327)
    Fold Change: 0.77
    Marker Score: 274
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 0.77
    Marker Score: 813
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: 0.76
    Marker Score: 198
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 395
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.76
    Marker Score: 659
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 0.74
    Marker Score: 1686
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.74
    Marker Score: 675
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 0.73
    Marker Score: 211
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 0.71
    Marker Score: 2969
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.69
    Marker Score: 457
  • Cell Name: monocyte (CL0000576)
    Fold Change: 0.69
    Marker Score: 895
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.68
    Marker Score: 2872.5
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 0.68
    Marker Score: 1726
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.68
    Marker Score: 706
  • Cell Name: blood vessel smooth muscle cell (CL0019018)
    Fold Change: 0.68
    Marker Score: 178
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: 0.65
    Marker Score: 540
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.64
    Marker Score: 305
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.62
    Marker Score: 683
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.59
    Marker Score: 147
  • Cell Name: neuronal receptor cell (CL0000006)
    Fold Change: 0.57
    Marker Score: 253
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.57
    Marker Score: 453
  • Cell Name: club cell (CL0000158)
    Fold Change: 0.57
    Marker Score: 662
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.56
    Marker Score: 1191
  • Cell Name: nephron tubule epithelial cell (CL1000494)
    Fold Change: 0.56
    Marker Score: 132
  • Cell Name: basal cell (CL0000646)
    Fold Change: 0.56
    Marker Score: 723
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 0.56
    Marker Score: 1073.5
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 0.55
    Marker Score: 528
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 0.55
    Marker Score: 424
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 0.55
    Marker Score: 1944
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 0.54
    Marker Score: 860
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 0.54
    Marker Score: 889
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.53
    Marker Score: 338
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 0.51
    Marker Score: 2439
  • Cell Name: podocyte (CL0000653)
    Fold Change: 0.51
    Marker Score: 187
  • Cell Name: dendritic cell (CL0000451)
    Fold Change: 0.47
    Marker Score: 321
  • Cell Name: T cell (CL0000084)
    Fold Change: 0.47
    Marker Score: 807
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 0.46
    Marker Score: 276
  • Cell Name: renal intercalated cell (CL0005010)
    Fold Change: 0.46
    Marker Score: 244
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.45
    Marker Score: 451
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: 0.44
    Marker Score: 86
  • Cell Name: ionocyte (CL0005006)
    Fold Change: 0.42
    Marker Score: 127.5
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: 0.42
    Marker Score: 3278
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.41
    Marker Score: 119
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: 0.41
    Marker Score: 109
  • Cell Name: epithelial cell of stratum germinativum of esophagus (CL1000447)
    Fold Change: 0.41
    Marker Score: 99
  • Cell Name: mucus secreting cell (CL0000319)
    Fold Change: 0.41
    Marker Score: 104
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 0.41
    Marker Score: 1278
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.39
    Marker Score: 264
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.38
    Marker Score: 3311.5
  • Cell Name: intestine goblet cell (CL0019031)
    Fold Change: 0.38
    Marker Score: 368
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 0.37
    Marker Score: 135
  • Cell Name: ciliated cell (CL0000064)
    Fold Change: 0.37
    Marker Score: 1278

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Other Information

**Key characteristics:** * ITGB6 is a transmembrane protein with a predicted molecular weight of approximately 140 kDa. * It is expressed in high levels in epithelial cells, including type B pancreatic cells, megakaryocytes, and basal epithelial cells of the tracheobronchial tree. * ITGB6 is also expressed in other cell types, including hematopoietic stem cells, pneumocytes, bladder urothelial cells, and cardiac endothelial cells. **Pathways and functions:** * ITGB6 is involved in cell-matrix adhesion by binding to extracellular matrix proteins, such as collagen and fibronectin. * ITGB6 is also involved in cell adhesion to other cells through its interactions with integrins on neighboring cells. * ITGB6 is involved in cell morphogenesis by promoting cell migration and adhesion. * ITGB6 is also involved in the organization of the ECM by interacting with other ECM proteins, such as collagen and proteoglycans. * ITGB6 is involved in the immune response by binding to ligands on immune cells, such as CD11a and CD11b. * ITGB6 is also involved in the inflammatory response by binding to inflammatory cytokines and signaling through the TGFB receptor pathway. **Clinical significance:** * Mutations in ITGB6 have been linked to several human diseases, including cancer, cardiovascular disease, and autoimmune disorders. * Targeting ITGB6 has been investigated as a therapeutic strategy for these diseases. * In one study, silencing ITGB6 in cancer cells reduced their ability to migrate and grow. * In another study, blocking ITGB6 with an antibody improved the anti-tumor activity of immune checkpoint blockade antibodies.

Genular Protein ID: 2926514725

Symbol: ITB6_HUMAN

Name: Integrin beta-6

UniProtKB Accession Codes:

P18564 B2R9W5 C9JA97 Q0VA95 Q16500 Q53RG5 Q53RR6

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CORUM 1 CTD 1 ChEBI 14 ChEMBL 1 ChiTaRS 1 ComplexPortal 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 1 ELM 1 EMBL 7 EMDB 4 EPD 1 Ensembl 3 ExpressionAtlas 1 GO 37 Gene3D 6 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PDB 16 PDBsum 9 PIR 1 PIRSF 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 5 RefSeq 4 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 5 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2365683

Title: Complete amino acid sequence of a novel integrin beta subunit (beta 6) identified in epithelial cells using the polymerase chain reaction.

PubMed ID: 2365683

DOI: 10.1016/s0021-9258(19)38425-x

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1382574

Title: The gene organization of the human beta 7 subunit, the common beta subunit of the leukocyte integrins HML-1 and LPAM-1.

PubMed ID: 1382574

DOI: 10.1093/intimm/4.9.1031

PubMed ID: 9426447

Title: Integrin alpha v beta 6 enhances coxsackievirus B1 lytic infection of human colon cancer cells.

PubMed ID: 9426447

DOI: 10.1006/viro.1997.8831

PubMed ID: 11807098

Title: Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin (beta) subunits.

PubMed ID: 11807098

DOI: 10.1083/jcb.200103037

PubMed ID: 15184403

Title: Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1.

PubMed ID: 15184403

DOI: 10.1083/jcb.200312172

PubMed ID: 15194773

Title: Integrin alpha v beta 6 is an RGD-dependent receptor for coxsackievirus A9.

PubMed ID: 15194773

DOI: 10.1128/jvi.78.13.6967-6973.2004

PubMed ID: 17545607

Title: HS1-associated protein X-1 regulates carcinoma cell migration and invasion via clathrin-mediated endocytosis of integrin alphavbeta6.

PubMed ID: 17545607

DOI: 10.1158/0008-5472.can-07-0318

PubMed ID: 17158881

Title: alphaVbeta6 is a novel receptor for human fibrillin-1. Comparative studies of molecular determinants underlying integrin-rgd affinity and specificity.

PubMed ID: 17158881

DOI: 10.1074/jbc.m607008200

PubMed ID: 22278742

Title: GARP regulates the bioavailability and activation of TGFbeta.

PubMed ID: 22278742

DOI: 10.1091/mbc.e11-12-1018

PubMed ID: 24367260

Title: alphavbeta6- and alphavbeta8-integrins serve as interchangeable receptors for HSV gH/gL to promote endocytosis and activation of membrane fusion.

PubMed ID: 24367260

DOI: 10.1371/journal.ppat.1003806

PubMed ID: 25383667

Title: Structural determinants of integrin beta-subunit specificity for latent TGF-beta.

PubMed ID: 25383667

DOI: 10.1038/nsmb.2905

PubMed ID: 28117447

Title: Force interacts with macromolecular structure in activation of TGF-beta.

PubMed ID: 28117447

DOI: 10.1038/nature21035

PubMed ID: 24319098

Title: A missense mutation in ITGB6 causes pitted hypomineralized amelogenesis imperfecta.

PubMed ID: 24319098

DOI: 10.1093/hmg/ddt616

PubMed ID: 24305999

Title: ITGB6 loss-of-function mutations cause autosomal recessive amelogenesis imperfecta.

PubMed ID: 24305999

DOI: 10.1093/hmg/ddt611

Sequence Information:

  • Length: 788
  • Mass: 85936
  • Checksum: EDB7D533EC4C8C4D
  • Sequence:
    • MGIELLCLFF LFLGRNDHVQ GGCALGGAET CEDCLLIGPQ CAWCAQENFT HPSGVGERCD 
TPANLLAKGC QLNFIENPVS QVEILKNKPL SVGRQKNSSD IVQIAPQSLI LKLRPGGAQT 
LQVHVRQTED YPVDLYYLMD LSASMDDDLN TIKELGSRLS KEMSKLTSNF RLGFGSFVEK 
PVSPFVKTTP EEIANPCSSI PYFCLPTFGF KHILPLTNDA ERFNEIVKNQ KISANIDTPE 
GGFDAIMQAA VCKEKIGWRN DSLHLLVFVS DADSHFGMDS KLAGIVIPND GLCHLDSKNE 
YSMSTVLEYP TIGQLIDKLV QNNVLLIFAV TQEQVHLYEN YAKLIPGATV GLLQKDSGNI 
LQLIISAYEE LRSEVELEVL GDTEGLNLSF TAICNNGTLF QHQKKCSHMK VGDTASFSVT 
VNIPHCERRS RHIIIKPVGL GDALELLVSP ECNCDCQKEV EVNSSKCHHG NGSFQCGVCA 
CHPGHMGPRC ECGEDMLSTD SCKEAPDHPS CSGRGDCYCG QCICHLSPYG NIYGPYCQCD 
NFSCVRHKGL LCGGNGDCDC GECVCRSGWT GEYCNCTTST DSCVSEDGVL CSGRGDCVCG 
KCVCTNPGAS GPTCERCPTC GDPCNSKRSC IECHLSAAGQ AREECVDKCK LAGATISEEE 
DFSKDGSVSC SLQGENECLI TFLITTDNEG KTIIHSINEK DCPKPPNIPM IMLGVSLAIL 
LIGVVLLCIW KLLVSFHDRK EVAKFEAERS KAKWQTGTNP LYRGSTSTFK NVTYKHREKQ 
KVDLSTDC

Genular Protein ID: 3439987401

Symbol: B4E2B8_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4E2B8

Database IDs:

ARBA 16 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 5 Gene3D 5 GenomeRNAi 1 InterPro 9 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 1 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 5 RefSeq 1 RuleBase 1 SAM 1 SMART 6 SUPFAM 4

Sequence Information:

  • Length: 746
  • Mass: 81522
  • Checksum: E435089EF5DD0367
  • Sequence:
    • MITYKNFTHP SGVGERCDTP ANLLAKGCQL NFIENPVSQV EILKNKPLSV GRQKNSSDIV 
QIAPQSLILK LRPGGAQTLQ VHVRQTEDYP VDLYYLMDLS ASMDDDLNTI KELGSRLSKE 
MSKLTSNFRL GFGSFVEKPV SPFVKTTPEE IANPCSSIPY FCLPTFGFKH ILPLTNDAER 
FNEIVKNQKI SANIDTPEGG FDAIMQAAVC KEKIGWRNDS LHLLVFVSDA DSHFGMDSKL 
AGIVIPNDGL CHLDSKNEYS MSTVLEYPTI GQLIDKLVQN NVLLIFAVTQ EQVHLYENYA 
KLIPGATVGL LQKDSGNILQ LIISAYEELR SEVELEVLGD TEGLNLSFTA ICNNGTLFQH 
QKKCSHMKVG DTASFSVTVN IPHCERRSRH IIIKPVGLGD ALELLVSPEC NCDCQKEVEV 
NSSKCHHGNG SFQCGVCACH PGHMGPRCEC GEDMLSTDPC KEAPDHPSCS GRGDCYCGQC 
ICHLSPYGNI YGPYCQCDNF SCVRHKGLLC GGNGDCDCGE CVCRSGWTGE YCNCTTSTDS 
CVSEDGVLCS GRGDCVCGKC VCTNPGASGP TCERCPTCGD PCNSKRSCIE CHLSAAGQAR 
EECVDKCKLA GATISEEEDF SKDGSVSCSL QGENECLITF LITTDNEGKT IIHSINEKDC 
PKPPNIPVIM LGVSLAILLI GVVLLCIWKL LVSFHDRKEV AKFEAERSKA KWQTGTNPLY 
RGSTSTFKNV TYKHREKQKV DLSTDC

Genular Protein ID: 2098844688

Symbol: A0A087WXP3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WXP3

Database IDs:

ARBA 16 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 8 Gene3D 5 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 9 MassIVE 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 5 Proteomes 2 RefSeq 1 RuleBase 1 SAM 2 SMART 6 SMR 1 SUPFAM 4 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 693
  • Mass: 75849
  • Checksum: F04FC7553E9228C7
  • Sequence:
    • MGIELLCLFF LFLGRNDHVQ GGAQTLQVHV RQTEDYPVDL YYLMDLSASM DDDLNTIKEL 
GSRLSKEMSK LTSNFRLGFG SFVEKPVSPF VKTTPEEIAN PCSSIPYFCL PTFGFKHILP 
LTNDAERFNE IVKNQKISAN IDTPEGGFDA IMQAAVCKEK IGWRNDSLHL LVFVSDADSH 
FGMDSKLAGI VIPNDGLCHL DSKNEYSMST VLEYPTIGQL IDKLVQNNVL LIFAVTQEQV 
HLYENYAKLI PGATVGLLQK DSGNILQLII SAYEELRSEV ELEVLGDTEG LNLSFTAICN 
NGTLFQHQKK CSHMKVGDTA SFSVTVNIPH CERRSRHIII KPVGLGDALE LLVSPECNCD 
CQKEVEVNSS KCHHGNGSFQ CGVCACHPGH MGPRCECGED MLSTDSCKEA PDHPSCSGRG 
DCYCGQCICH LSPYGNIYGP YCQCDNFSCV RHKGLLCGGN GDCDCGECVC RSGWTGEYCN 
CTTSTDSCVS EDGVLCSGRG DCVCGKCVCT NPGASGPTCE RCPTCGDPCN SKRSCIECHL 
SAAGQAREEC VDKCKLAGAT ISEEEDFSKD GSVSCSLQGE NECLITFLIT TDNEGKTIIH 
SINEKDCPKP PNIPMIMLGV SLAILLIGVV LLCIWKLLVS FHDRKEVAKF EAERSKAKWQ 
TGTNPLYRGS TSTFKNVTYK HREKQKVDLS TDC

Genular Protein ID: 857721210

Symbol: E9PEE8_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PEE8

Database IDs:

ARBA 16 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 EPD 1 Ensembl 2 ExpressionAtlas 1 GO 8 Gene3D 5 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 9 MassIVE 1 MaxQB 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSF 1 PIRSR 1 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 5 Proteomes 2 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1 SMART 6 SMR 1 SUPFAM 4 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

Sequence Information:

  • Length: 746
  • Mass: 81544
  • Checksum: A3767C1EEB3DF1CD
  • Sequence:
    • MITYKNFTHP SGVGERCDTP ANLLAKGCQL NFIENPVSQV EILKNKPLSV GRQKNSSDIV 
QIAPQSLILK LRPGGAQTLQ VHVRQTEDYP VDLYYLMDLS ASMDDDLNTI KELGSRLSKE 
MSKLTSNFRL GFGSFVEKPV SPFVKTTPEE IANPCSSIPY FCLPTFGFKH ILPLTNDAER 
FNEIVKNQKI SANIDTPEGG FDAIMQAAVC KEKIGWRNDS LHLLVFVSDA DSHFGMDSKL 
AGIVIPNDGL CHLDSKNEYS MSTVLEYPTI GQLIDKLVQN NVLLIFAVTQ EQVHLYENYA 
KLIPGATVGL LQKDSGNILQ LIISAYEELR SEVELEVLGD TEGLNLSFTA ICNNGTLFQH 
QKKCSHMKVG DTASFSVTVN IPHCERRSRH IIIKPVGLGD ALELLVSPEC NCDCQKEVEV 
NSSKCHHGNG SFQCGVCACH PGHMGPRCEC GEDMLSTDSC KEAPDHPSCS GRGDCYCGQC 
ICHLSPYGNI YGPYCQCDNF SCVRHKGLLC GGNGDCDCGE CVCRSGWTGE YCNCTTSTDS 
CVSEDGVLCS GRGDCVCGKC VCTNPGASGP TCERCPTCGD PCNSKRSCIE CHLSAAGQAR 
EECVDKCKLA GATISEEEDF SKDGSVSCSL QGENECLITF LITTDNEGKT IIHSINEKDC 
PKPPNIPMIM LGVSLAILLI GVVLLCIWKL LVSFHDRKEV AKFEAERSKA KWQTGTNPLY 
RGSTSTFKNV TYKHREKQKV DLSTDC

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.