Details for: KCNK2
Associated with
Cells (max top 100)
(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: kidney proximal convoluted tubule epithelial cell (CL1000838)
Fold Change: 2.36
Marker Score: 4891 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 1.88
Marker Score: 927 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: 1.71
Marker Score: 14724 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.55
Marker Score: 95304 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 1.47
Marker Score: 26173 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: 1.37
Marker Score: 13006 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 1.35
Marker Score: 2750 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.33
Marker Score: 26386 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 1.32
Marker Score: 2497 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: 1.28
Marker Score: 2454 - Cell Name: vip GABAergic cortical interneuron (CL4023016)
Fold Change: 1.27
Marker Score: 48258 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: 1.13
Marker Score: 681 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: 1.12
Marker Score: 3195 - Cell Name: neural crest cell (CL0011012)
Fold Change: 1.08
Marker Score: 1156 - Cell Name: vascular leptomeningeal cell (CL4023051)
Fold Change: 1.04
Marker Score: 1200 - Cell Name: migratory enteric neural crest cell (CL0002607)
Fold Change: 1
Marker Score: 945 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71814 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48039 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30408 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2413 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.94
Marker Score: 5350 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.92
Marker Score: 2741 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: 0.89
Marker Score: 3696 - Cell Name: neuron (CL0000540)
Fold Change: 0.88
Marker Score: 3575 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5285 - Cell Name: peripheral nervous system neuron (CL2000032)
Fold Change: 0.87
Marker Score: 978 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.78
Marker Score: 1261 - Cell Name: brush cell (CL0002204)
Fold Change: 0.77
Marker Score: 707 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.77
Marker Score: 12117 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.76
Marker Score: 396 - Cell Name: renal alpha-intercalated cell (CL0005011)
Fold Change: 0.73
Marker Score: 385 - Cell Name: meningeal macrophage (CL0000879)
Fold Change: 0.68
Marker Score: 192 - Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
Fold Change: 0.67
Marker Score: 423 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.67
Marker Score: 24819 - Cell Name: retinal bipolar neuron (CL0000748)
Fold Change: 0.63
Marker Score: 5337 - Cell Name: oligodendrocyte precursor cell (CL0002453)
Fold Change: 0.62
Marker Score: 765 - Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
Fold Change: 0.58
Marker Score: 1376 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.58
Marker Score: 258 - Cell Name: goblet cell (CL0000160)
Fold Change: 0.56
Marker Score: 3751 - Cell Name: renal beta-intercalated cell (CL0002201)
Fold Change: 0.56
Marker Score: 178.5 - Cell Name: intestinal enteroendocrine cell (CL1001516)
Fold Change: 0.56
Marker Score: 444 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: 0.55
Marker Score: 2549 - Cell Name: mononuclear cell (CL0000842)
Fold Change: 0.53
Marker Score: 170 - Cell Name: smooth muscle myoblast (CL0000514)
Fold Change: 0.51
Marker Score: 243 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.48
Marker Score: 185 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.46
Marker Score: 15673 - Cell Name: motor neuron (CL0000100)
Fold Change: 0.45
Marker Score: 265 - Cell Name: peptic cell (CL0000155)
Fold Change: 0.43
Marker Score: 182 - Cell Name: interneuron (CL0000099)
Fold Change: 0.43
Marker Score: 198 - Cell Name: glial cell (CL0000125)
Fold Change: 0.43
Marker Score: 474 - Cell Name: neuronal receptor cell (CL0000006)
Fold Change: 0.4
Marker Score: 177 - Cell Name: reticular cell (CL0000432)
Fold Change: 0.37
Marker Score: 136 - Cell Name: respiratory basal cell (CL0002633)
Fold Change: 0.36
Marker Score: 513 - Cell Name: neural cell (CL0002319)
Fold Change: 0.35
Marker Score: 171 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: 0.34
Marker Score: 339 - Cell Name: enteric neuron (CL0007011)
Fold Change: 0.34
Marker Score: 180 - Cell Name: inhibitory motor neuron (CL0008015)
Fold Change: 0.34
Marker Score: 159 - Cell Name: connective tissue cell (CL0002320)
Fold Change: 0.33
Marker Score: 86 - Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
Fold Change: 0.32
Marker Score: 107 - Cell Name: mast cell (CL0000097)
Fold Change: 0.32
Marker Score: 183 - Cell Name: preosteoblast (CL0007010)
Fold Change: 0.3
Marker Score: 86 - Cell Name: kidney capillary endothelial cell (CL1000892)
Fold Change: 0.3
Marker Score: 94 - Cell Name: plasma cell (CL0000786)
Fold Change: 0.29
Marker Score: 325 - Cell Name: brainstem motor neuron (CL2000047)
Fold Change: 0.29
Marker Score: 168 - Cell Name: stellate neuron (CL0000122)
Fold Change: 0.27
Marker Score: 1447 - Cell Name: rod bipolar cell (CL0000751)
Fold Change: 0.27
Marker Score: 139 - Cell Name: retinal pigment epithelial cell (CL0002586)
Fold Change: 0.25
Marker Score: 74 - Cell Name: blood vessel endothelial cell (CL0000071)
Fold Change: 0.25
Marker Score: 253 - Cell Name: pyramidal neuron (CL0000598)
Fold Change: 0.25
Marker Score: 422 - Cell Name: Schwann cell precursor (CL0002375)
Fold Change: 0.25
Marker Score: 62 - Cell Name: osteoblast (CL0000062)
Fold Change: 0.25
Marker Score: 133 - Cell Name: mesenchymal stem cell (CL0000134)
Fold Change: 0.24
Marker Score: 368 - Cell Name: ependymal cell (CL0000065)
Fold Change: 0.23
Marker Score: 81 - Cell Name: fibroblast of breast (CL4006000)
Fold Change: 0.23
Marker Score: 132 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: 0.23
Marker Score: 137 - Cell Name: podocyte (CL0000653)
Fold Change: 0.23
Marker Score: 84 - Cell Name: astrocyte (CL0000127)
Fold Change: 0.21
Marker Score: 183 - Cell Name: neuronal brush cell (CL0000555)
Fold Change: 0.21
Marker Score: 702 - Cell Name: oligodendrocyte (CL0000128)
Fold Change: 0.2
Marker Score: 487.5 - Cell Name: melanocyte (CL0000148)
Fold Change: 0.2
Marker Score: 79 - Cell Name: interstitial cell of Cajal (CL0002088)
Fold Change: 0.19
Marker Score: 65 - Cell Name: B cell (CL0000236)
Fold Change: 0.18
Marker Score: 172 - Cell Name: endothelial cell (CL0000115)
Fold Change: 0.18
Marker Score: 159 - Cell Name: cerebellar granule cell precursor (CL0002362)
Fold Change: 0.17
Marker Score: 97 - Cell Name: ciliated epithelial cell (CL0000067)
Fold Change: 0.17
Marker Score: 76 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 0.16
Marker Score: 126 - Cell Name: tracheal goblet cell (CL1000329)
Fold Change: 0.16
Marker Score: 452 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.16
Marker Score: 35 - Cell Name: stromal cell (CL0000499)
Fold Change: 0.16
Marker Score: 185 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.14
Marker Score: 141 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 0.14
Marker Score: 28 - Cell Name: blood vessel smooth muscle cell (CL0019018)
Fold Change: 0.14
Marker Score: 36 - Cell Name: central nervous system macrophage (CL0000878)
Fold Change: 0.14
Marker Score: 68 - Cell Name: skin fibroblast (CL0002620)
Fold Change: 0.13
Marker Score: 35 - Cell Name: pericyte (CL0000669)
Fold Change: 0.13
Marker Score: 78 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 0.13
Marker Score: 796 - Cell Name: ON retinal ganglion cell (CL4023032)
Fold Change: 0.13
Marker Score: 36 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 0.13
Marker Score: 140 - Cell Name: granule cell (CL0000120)
Fold Change: 0.13
Marker Score: 979 - Cell Name: bronchial epithelial cell (CL0002328)
Fold Change: 0.13
Marker Score: 34
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Other Information
Genular Protein ID: 1042329577
Symbol: KCNK2_HUMAN
Name: Potassium channel subfamily K member 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10321245
Title: Inhalational anesthetics activate two-pore-domain background K+ channels.
PubMed ID: 10321245
DOI: 10.1038/8084
PubMed ID: 10784345
Title: Cloning, localisation and functional expression of the human orthologue of the TREK-1 potassium channel.
PubMed ID: 10784345
PubMed ID: 24196565
Title: A splice variant of the two-pore domain potassium channel TREK-1 with only one pore domain reduces the surface expression of full-length TREK-1 channels.
PubMed ID: 24196565
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 11319556
Title: KCNK2: reversible conversion of a hippocampal potassium leak into a voltage-dependent channel.
PubMed ID: 11319556
DOI: 10.1038/87434
PubMed ID: 23169818
Title: SUMOylation silences heterodimeric TASK potassium channels containing K2P1 subunits in cerebellar granule neurons.
PubMed ID: 23169818
PubMed ID: 26642364
Title: POPDC1S201F causes muscular dystrophy and arrhythmia by affecting protein trafficking.
PubMed ID: 26642364
DOI: 10.1172/jci79562
Sequence Information:
- Length: 426
- Mass: 47093
- Checksum: DB10382B1803DA13
- Sequence:
MLPSASRERP GYRAGVAAPD LLDPKSAAQN SKPRLSFSTK PTVLASRVES DTTINVMKWK TVSTIFLVVV LYLIIGATVF KALEQPHEIS QRTTIVIQKQ TFISQHSCVN STELDELIQQ IVAAINAGII PLGNTSNQIS HWDLGSSFFF AGTVITTIGF GNISPRTEGG KIFCIIYALL GIPLFGFLLA GVGDQLGTIF GKGIAKVEDT FIKWNVSQTK IRIISTIIFI LFGCVLFVAL PAIIFKHIEG WSALDAIYFV VITLTTIGFG DYVAGGSDIE YLDFYKPVVW FWILVGLAYF AAVLSMIGDW LRVISKKTKE EVGEFRAHAA EWTANVTAEF KETRRRLSVE IYDKFQRATS IKRKLSAELA GNHNQELTPC RRTLSVNHLT SERDVLPPLL KTESIYLNGL TPHCAGEEIA VIENIK
Genular Protein ID: 782303559
Symbol: U3N6F0_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 411
- Mass: 45495
- Checksum: FDE40CAB21B42A1C
- Sequence:
MAAPDLLDPK SAAQNSKPRL SFSTKPTVLA SRVESDTTIN VMKWKTVSTI FLVVVLYLII GATVFKALEQ PHEISQRTTI VIQKQTFISQ HSCVNSTELD ELIQQIVAAI NAGIIPLGNT SNQISHWDLG SSFFFAGTVI TTIGFGNISP RTEGGKIFCI IYALLGIPLF GFLLAGVGDQ LGTIFGKGIA KVEDTFIKWN VSQTKIRIIS TIIFILFGCV LFVALPAIIF KHIEGWSALD AIYFVVITLT TIGFGDYVAG GSDIEYLDFY KPVVWFWILV GLAYFAAVLS MIGDWLRVIS KKTKEEVGEF RAHAAEWTAN VTAEFKETRR RLSVEIYDKF QRATSIKRKL SAELAGNHNQ ELTPCRRTLS VNHLTSERDV LPPLLKTESI YLNGLTPHCA GEEIAVIENI K
Genular Protein ID: 3940273243
Symbol: Q6ZW95_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
Sequence Information:
- Length: 152
- Mass: 17248
- Checksum: DC9BF5C52AC672AB
- Sequence:
MMNPRAKRDF YLAAPDLLDP KSAAQNSKPR LSFSTKPTVL ASRVESDTTI NVMKWKTVST IFLVVVLYLI IGATVFKALE QPHEISQRTT IVIQKQTFIS QHSCVNSTEL DELIQDLETS HHAQKAAKYS VSSMPYWEFP SLVFSWLELE IS
Genular Protein ID: 2967993962
Symbol: U3N834_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 422
- Mass: 46888
- Checksum: 1AD4E0B5C1B6CBE7
- Sequence:
MMNPRAKRDF YLAAPDLLDP KSAAQNSKPR LSFSTKPTVL ASRVESDTTI NVMKWKTVST IFLVVVLYLI IGATVFKALE QPHEISQRTT IVIQKQTFIS QHSCVNSTEL DELIQQIVAA INAGIIPLGN TSNQISHWDL GSSFFFAGTV ITTIGFGNIS PRTEGGKIFC IIYALLGIPL FGFLLAGVGD QLGTIFGKGI AKVEDTFIKW NVSQTKIRII STIIFILFGC VLFVALPAII FKHIEGWSAL DAIYFVVITL TTIGFGDYVA GGSDIEYLDF YKPVVWFWIL VGLAYFAAVL SMIGDWLRVI SKKTKEEVGE FRAHAAEWTA NVTAEFKETR RRLSVEIYDK FQRATSIKRK LSAELAGNHN QELTPCRRTL SVNHLTSERD VLPPLLKTES IYLNGLTPHC AGEEIAVIEN IK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.