Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 119.0613
Cell Significance Index: 354.0900 - Cell Name: oral mucosa squamous cell (CL1001576)
Fold Change: 71.8655
Cell Significance Index: 617.5400 - Cell Name: epidermal cell (CL0000362)
Fold Change: 21.2954
Cell Significance Index: 48.0100 - Cell Name: reticular cell (CL0000432)
Fold Change: 13.8644
Cell Significance Index: 88.3300 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: 10.9803
Cell Significance Index: 776.5700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 9.4125
Cell Significance Index: -20.6000 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 7.9546
Cell Significance Index: 108.5300 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 7.6918
Cell Significance Index: 3400.7200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 4.0635
Cell Significance Index: 113.5600 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 2.1010
Cell Significance Index: 18.6500 - Cell Name: basal-myoepithelial cell of mammary gland (CL0002324)
Fold Change: 1.8626
Cell Significance Index: 13.7900 - Cell Name: epithelial cell of stratum germinativum of esophagus (CL1000447)
Fold Change: 1.4591
Cell Significance Index: 11.9200 - Cell Name: epithelial cell of lacrimal sac (CL1000436)
Fold Change: 1.4494
Cell Significance Index: 10.4300 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.3003
Cell Significance Index: 167.9900 - Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: 1.1677
Cell Significance Index: 19.9600 - Cell Name: megakaryocyte (CL0000556)
Fold Change: 0.9715
Cell Significance Index: 15.7400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: 0.9398
Cell Significance Index: 44.1700 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.8885
Cell Significance Index: 169.1000 - Cell Name: endothelial tip cell (CL0000704)
Fold Change: 0.5744
Cell Significance Index: 2.4700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.4259
Cell Significance Index: 42.1400 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.4154
Cell Significance Index: 375.0900 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: 0.3360
Cell Significance Index: 25.0400 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.2780
Cell Significance Index: 7.9700 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.2412
Cell Significance Index: 26.2400 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2308
Cell Significance Index: 37.5400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.2117
Cell Significance Index: 12.7100 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 0.1311
Cell Significance Index: 0.8700 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.1297
Cell Significance Index: 1.6700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0885
Cell Significance Index: 6.1200 - Cell Name: precursor B cell (CL0000817)
Fold Change: 0.0309
Cell Significance Index: 0.4000 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.0230
Cell Significance Index: 0.3200 - Cell Name: extravillous trophoblast (CL0008036)
Fold Change: 0.0225
Cell Significance Index: 0.1400 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0069
Cell Significance Index: 0.2000 - Cell Name: neuron associated cell (CL0000095)
Fold Change: 0.0014
Cell Significance Index: 0.0600 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0018
Cell Significance Index: -0.0900 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0021
Cell Significance Index: -0.1300 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0040
Cell Significance Index: -0.1800 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0076
Cell Significance Index: -0.3300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0095
Cell Significance Index: -17.8800 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.0114
Cell Significance Index: -0.1300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0201
Cell Significance Index: -0.7100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0210
Cell Significance Index: -15.8800 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0218
Cell Significance Index: -3.9300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0222
Cell Significance Index: -16.4700 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0244
Cell Significance Index: -0.6100 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0246
Cell Significance Index: -13.8800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0264
Cell Significance Index: -16.5100 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0339
Cell Significance Index: -18.5400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0395
Cell Significance Index: -17.9400 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0399
Cell Significance Index: -5.1200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0435
Cell Significance Index: -15.6200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0660
Cell Significance Index: -4.1600 - Cell Name: vascular lymphangioblast (CL0005022)
Fold Change: -0.0755
Cell Significance Index: -1.3400 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0755
Cell Significance Index: -15.9000 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0769
Cell Significance Index: -9.4500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0774
Cell Significance Index: -2.4800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0839
Cell Significance Index: -9.7800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0888
Cell Significance Index: -17.8100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0892
Cell Significance Index: -17.7000 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -0.0922
Cell Significance Index: -1.3900 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0951
Cell Significance Index: -2.0600 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1064
Cell Significance Index: -18.1700 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.1077
Cell Significance Index: -2.6900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1131
Cell Significance Index: -16.4400 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.1131
Cell Significance Index: -1.6100 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1209
Cell Significance Index: -3.2900 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.1379
Cell Significance Index: -18.9400 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.1437
Cell Significance Index: -16.9500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.1448
Cell Significance Index: -6.7500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1591
Cell Significance Index: -18.2300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1624
Cell Significance Index: -16.5900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1708
Cell Significance Index: -4.5600 - Cell Name: progenitor cell (CL0011026)
Fold Change: -0.2043
Cell Significance Index: -2.1700 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.2203
Cell Significance Index: -4.5700 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.2242
Cell Significance Index: -8.2300 - Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
Fold Change: -0.2519
Cell Significance Index: -1.5500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.2571
Cell Significance Index: -19.7300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.3242
Cell Significance Index: -6.9100 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.3603
Cell Significance Index: -9.1800 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3755
Cell Significance Index: -21.0700 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: -0.4062
Cell Significance Index: -6.2900 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: -0.4540
Cell Significance Index: -2.8100 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.4610
Cell Significance Index: -16.1500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.4709
Cell Significance Index: -20.8300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.4867
Cell Significance Index: -25.2800 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.5140
Cell Significance Index: -16.8300 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.5266
Cell Significance Index: -16.7700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.5480
Cell Significance Index: -20.7500 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.5841
Cell Significance Index: -12.7900 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.5972
Cell Significance Index: -17.5900 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.6400
Cell Significance Index: -16.8300 - Cell Name: basal cell (CL0000646)
Fold Change: -0.6479
Cell Significance Index: -7.7100 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.6514
Cell Significance Index: -18.5900 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.6561
Cell Significance Index: -16.3600 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.6567
Cell Significance Index: -16.3800 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.6999
Cell Significance Index: -17.8800 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.7386
Cell Significance Index: -17.8900 - Cell Name: seromucus secreting cell (CL0000159)
Fold Change: -0.7782
Cell Significance Index: -16.2300 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.7874
Cell Significance Index: -16.8300 - Cell Name: adipocyte of breast (CL0002617)
Fold Change: -0.8068
Cell Significance Index: -10.1600
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3768819188
Symbol: K1C14_HUMAN
Name: Keratin, type I cytoskeletal 14
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 6210150
Title: Remarkable conservation of structure among intermediate filament genes.
PubMed ID: 6210150
PubMed ID: 2580298
Title: Complete sequence of a gene encoding a human type I keratin: sequences homologous to enhancer elements in the regulatory region of the gene.
PubMed ID: 2580298
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 6186381
Title: The cDNA sequence of a human epidermal keratin: divergence of sequence but conservation of structure among intermediate filament proteins.
PubMed ID: 6186381
PubMed ID: 8601736
Title: Genetic analysis of a severe case of Dowling-Meara epidermolysis bullosa simplex.
PubMed ID: 8601736
PubMed ID: 1717157
Title: Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: genetic and functional analyses.
PubMed ID: 1717157
PubMed ID: 7526926
Title: A novel mutation of Leu122 to Phe at a highly conserved hydrophobic residue in the helix initiation motif of keratin 14 in epidermolysis bullosa simplex.
PubMed ID: 7526926
DOI: 10.1093/hmg/3.7.1171
PubMed ID: 9457912
Title: Characterization and chromosomal localization of human hair-specific keratin genes and comparative expression during the hair growth cycle.
PubMed ID: 9457912
PubMed ID: 10852826
Title: Interaction of plakophilins with desmoplakin and intermediate filament proteins: an in vitro analysis.
PubMed ID: 10852826
PubMed ID: 11684708
Title: Keratin attenuates tumor necrosis factor-induced cytotoxicity through association with TRADD.
PubMed ID: 11684708
PubMed ID: 11724817
Title: The nonhelical tail domain of keratin 14 promotes filament bundling and enhances the mechanical properties of keratin intermediate filaments in vitro.
PubMed ID: 11724817
PubMed ID: 14654843
Title: Proteomic characterization of the human centrosome by protein correlation profiling.
PubMed ID: 14654843
DOI: 10.1038/nature02166
PubMed ID: 18691976
Title: Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.
PubMed ID: 18691976
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 24940650
Title: Interaction of plectin with keratins 5 and 14: dependence on several plectin domains and keratin quaternary structure.
PubMed ID: 24940650
DOI: 10.1038/jid.2014.255
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 26758872
Title: Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy.
PubMed ID: 26758872
DOI: 10.1093/hmg/ddw001
PubMed ID: 27798626
Title: Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility.
PubMed ID: 27798626
DOI: 10.1038/ng.3701
PubMed ID: 32179842
Title: Serum lipids, retinoic acid and phenol red differentially regulate expression of keratins K1, K10 and K2 in cultured keratinocytes.
PubMed ID: 32179842
PubMed ID: 22705788
Title: Structural basis for heteromeric assembly and perinuclear organization of keratin filaments.
PubMed ID: 22705788
DOI: 10.1038/nsmb.2330
PubMed ID: 31995743
Title: Structure-Function Analyses of a Keratin Heterotypic Complex Identify Specific Keratin Regions Involved in Intermediate Filament Assembly.
PubMed ID: 31995743
PubMed ID: 1720261
Title: Epidermolysis bullosa simplex: evidence in two families for keratin gene abnormalities.
PubMed ID: 1720261
PubMed ID: 7506606
Title: A novel three-nucleotide deletion in the helix 2B region of keratin 14 in epidermolysis bullosa simplex: delta E375.
PubMed ID: 7506606
PubMed ID: 7682883
Title: A mutation (Met-->Arg) in the type I keratin (K14) gene responsible for autosomal dominant epidermolysis bullosa simplex.
PubMed ID: 7682883
PubMed ID: 7688405
Title: A keratin 14 mutational hot spot for epidermolysis bullosa simplex, Dowling-Meara: implications for diagnosis.
PubMed ID: 7688405
PubMed ID: 7526933
Title: A missense mutation in the rod domain of keratin 14 associated with recessive epidermolysis bullosa simplex.
PubMed ID: 7526933
DOI: 10.1038/ng0493-327
PubMed ID: 7506097
Title: Missing links: Weber-Cockayne keratin mutations implicate the L12 linker domain in effective cytoskeleton function.
PubMed ID: 7506097
DOI: 10.1038/ng1193-294
PubMed ID: 7561171
Title: Keratin 14 gene mutations in patients with epidermolysis bullosa simplex.
PubMed ID: 7561171
PubMed ID: 9284105
Title: Partial dominance of a keratin 14 mutation in epidermolysis bullosa simplex: increased severity of disease in a homozygote.
PubMed ID: 9284105
PubMed ID: 9804355
Title: Severe palmo-plantar hyperkeratosis in Dowling-Meara epidermolysis bullosa simplex caused by a mutation in the keratin 14 gene (KRT14).
PubMed ID: 9804355
PubMed ID: 9804357
Title: Novel K5 and K14 mutations in German patients with the Weber-Cockayne variant of epidermolysis bullosa simplex.
PubMed ID: 9804357
PubMed ID: 10583131
Title: A recurrent keratin 14 mutation in Dowling-Meara epidermolysis bullosa simplex.
PubMed ID: 10583131
PubMed ID: 9989794
Title: Identification of novel and known mutations in the genes for keratin 5 and 14 in Danish patients with epidermolysis bullosa simplex: correlation between genotype and phenotype.
PubMed ID: 9989794
PubMed ID: 10730767
Title: Laryngeal involvement in the Dowling-Meara variant of epidermolysis bullosa simplex with keratin mutations of severely disruptive potential.
PubMed ID: 10730767
PubMed ID: 10733662
Title: Exempting homologous pseudogene sequences from polymerase chain reaction amplification allows genomic keratin 14 hotspot analysis.
PubMed ID: 10733662
PubMed ID: 10820403
Title: DNA based prenatal testing for the skin blistering disorder epidermolysis bullosa simplex.
PubMed ID: 10820403
DOI: 10.1002/(sici)1097-0223(200005)20:5<371::aid-pd818>3.0.co;2-5
PubMed ID: 11710919
Title: Keratin 14 point mutations at codon 119 of helix 1A resulting in different epidermolysis bullosa simplex phenotypes.
PubMed ID: 11710919
PubMed ID: 12707098
Title: Epidermolysis bullosa simplex in Israel: clinical and genetic features.
PubMed ID: 12707098
PubMed ID: 12655565
Title: Mutation analysis of the entire keratin 5 and 14 genes in patients with epidermolysis bullosa simplex and identification of novel mutations.
PubMed ID: 12655565
DOI: 10.1002/humu.9124
PubMed ID: 12603865
Title: Long-range polymerase chain reaction for specific full-length amplification of the human keratin 14 gene and novel keratin 14 mutations in epidermolysis bullosa simplex patients.
PubMed ID: 12603865
PubMed ID: 14987259
Title: Novel keratin 14 gene mutations in patients from Hungary with epidermolysis bullosa simplex.
PubMed ID: 14987259
PubMed ID: 16960809
Title: Naegeli-Franceschetti-Jadassohn syndrome and dermatopathia pigmentosa reticularis: two allelic ectodermal dysplasias caused by dominant mutations in KRT14.
PubMed ID: 16960809
DOI: 10.1086/507792
PubMed ID: 16882168
Title: Epidermolysis bullosa simplex in Japanese and Korean patients: genetic studies in 19 cases.
PubMed ID: 16882168
PubMed ID: 16786515
Title: Novel and recurrent mutations in keratin KRT5 and KRT14 genes in epidermolysis bullosa simplex: implications for disease phenotype and keratin filament assembly.
PubMed ID: 16786515
DOI: 10.1002/humu.9437
PubMed ID: 21375516
Title: Mutations in KRT5 and KRT14 cause epidermolysis bullosa simplex in 75% of the patients.
PubMed ID: 21375516
PubMed ID: 22832485
Title: Digenic inheritance in epidermolysis bullosa simplex.
PubMed ID: 22832485
DOI: 10.1038/jid.2012.229
PubMed ID: 24981776
Title: Novel KRT14 mutation causing epidermolysis bullosa simplex with variable phenotype.
PubMed ID: 24981776
DOI: 10.1111/exd.12478
PubMed ID: 26432462
Title: Novel sporadic and recurrent mutations in KRT5 and KRT14 genes in Polish epidermolysis bullosa simplex patients: further insights into epidemiology and genotype-phenotype correlation.
PubMed ID: 26432462
Sequence Information:
- Length: 472
- Mass: 51561
- Checksum: 120BA30BA2F8E397
- Sequence:
MTTCSRQFTS SSSMKGSCGI GGGIGGGSSR ISSVLAGGSC RAPSTYGGGL SVSSSRFSSG GACGLGGGYG GGFSSSSSSF GSGFGGGYGG GLGAGLGGGF GGGFAGGDGL LVGSEKVTMQ NLNDRLASYL DKVRALEEAN ADLEVKIRDW YQRQRPAEIK DYSPYFKTIE DLRNKILTAT VDNANVLLQI DNARLAADDF RTKYETELNL RMSVEADING LRRVLDELTL ARADLEMQIE SLKEELAYLK KNHEEEMNAL RGQVGGDVNV EMDAAPGVDL SRILNEMRDQ YEKMAEKNRK DAEEWFFTKT EELNREVATN SELVQSGKSE ISELRRTMQN LEIELQSQLS MKASLENSLE ETKGRYCMQL AQIQEMIGSV EEQLAQLRCE MEQQNQEYKI LLDVKTRLEQ EIATYRRLLE GEDAHLSSSQ FSSGSQSSRD VTSSSRQIRT KVMDVHDGKV VSTHEQVLRT KN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.