Details for: LMX1B

Gene ID: 4010

Symbol: LMX1B

Ensembl ID: ENSG00000136944

Description: LIM homeobox transcription factor 1 beta

Associated with

  • Chromatin
    (GO:0000785)
  • Dna-binding transcription factor activity
    (GO:0003700)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dopaminergic neuron differentiation
    (GO:0071542)
  • Dorsal/ventral pattern formation
    (GO:0009953)
  • Metal ion binding
    (GO:0046872)
  • Neuron differentiation
    (GO:0030182)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of dna-templated transcription
    (GO:0006355)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 23.1759
    Cell Significance Index: 396.1700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 2.4821
    Cell Significance Index: 152.1800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.4913
    Cell Significance Index: 47.7700
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 1.3989
    Cell Significance Index: 20.3100
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 1.2024
    Cell Significance Index: 18.1200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.9635
    Cell Significance Index: 183.3700
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.6554
    Cell Significance Index: 10.8000
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.6028
    Cell Significance Index: 3.7100
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 0.4826
    Cell Significance Index: 3.2700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.4717
    Cell Significance Index: 11.7900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4503
    Cell Significance Index: 44.5400
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.3961
    Cell Significance Index: 8.4400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3902
    Cell Significance Index: 352.3500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.2765
    Cell Significance Index: 30.0800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2449
    Cell Significance Index: 14.7000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2403
    Cell Significance Index: 39.0900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.1667
    Cell Significance Index: 75.6700
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 0.1486
    Cell Significance Index: 2.2600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1401
    Cell Significance Index: 9.6900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.1390
    Cell Significance Index: 2.9100
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.1103
    Cell Significance Index: 1.7500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0764
    Cell Significance Index: 3.5900
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.0655
    Cell Significance Index: 0.9400
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0583
    Cell Significance Index: 25.7900
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: 0.0384
    Cell Significance Index: 0.8000
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.0359
    Cell Significance Index: 0.5300
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0355
    Cell Significance Index: 0.4900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0242
    Cell Significance Index: 4.8100
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: 0.0230
    Cell Significance Index: 0.2200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.0202
    Cell Significance Index: 0.9400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.0092
    Cell Significance Index: 0.6500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0066
    Cell Significance Index: 12.4000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0027
    Cell Significance Index: 5.0400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0025
    Cell Significance Index: 3.8900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0021
    Cell Significance Index: 2.8300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0017
    Cell Significance Index: 0.0500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0009
    Cell Significance Index: 0.0300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0003
    Cell Significance Index: 0.0600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0003
    Cell Significance Index: 0.0200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0003
    Cell Significance Index: -0.1500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0006
    Cell Significance Index: -0.4500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0007
    Cell Significance Index: -0.0100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0014
    Cell Significance Index: -0.0300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0021
    Cell Significance Index: -0.3100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0027
    Cell Significance Index: -1.7300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0033
    Cell Significance Index: -1.2000
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0070
    Cell Significance Index: -5.3200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0071
    Cell Significance Index: -5.1800
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0085
    Cell Significance Index: -2.4400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0088
    Cell Significance Index: -4.7800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0106
    Cell Significance Index: -2.2400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0106
    Cell Significance Index: -1.8100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0139
    Cell Significance Index: -0.6300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0140
    Cell Significance Index: -0.2400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0146
    Cell Significance Index: -1.8900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0196
    Cell Significance Index: -2.2500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0219
    Cell Significance Index: -3.9500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0222
    Cell Significance Index: -0.4800
  • Cell Name: paneth cell (CL0000510)
    Fold Change: -0.0222
    Cell Significance Index: -0.2300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0235
    Cell Significance Index: -2.4500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0351
    Cell Significance Index: -4.0900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0353
    Cell Significance Index: -4.3400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0356
    Cell Significance Index: -4.8900
  • Cell Name: luminal epithelial cell of mammary gland (CL0002326)
    Fold Change: -0.0450
    Cell Significance Index: -0.5800
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.0456
    Cell Significance Index: -0.6300
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0556
    Cell Significance Index: -1.4300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0569
    Cell Significance Index: -0.8100
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0574
    Cell Significance Index: -1.1200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0601
    Cell Significance Index: -4.0400
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.0647
    Cell Significance Index: -0.5500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0682
    Cell Significance Index: -5.2300
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.0691
    Cell Significance Index: -0.8700
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0719
    Cell Significance Index: -3.1800
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0743
    Cell Significance Index: -2.3500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0757
    Cell Significance Index: -2.0600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0797
    Cell Significance Index: -4.9000
  • Cell Name: osteoblast (CL0000062)
    Fold Change: -0.0866
    Cell Significance Index: -0.8400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0935
    Cell Significance Index: -3.2500
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0989
    Cell Significance Index: -1.2800
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0992
    Cell Significance Index: -2.4200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0998
    Cell Significance Index: -5.6000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.1006
    Cell Significance Index: -3.8100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1059
    Cell Significance Index: -5.3500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1071
    Cell Significance Index: -3.9300
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.1072
    Cell Significance Index: -1.4700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.1077
    Cell Significance Index: -2.8900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1095
    Cell Significance Index: -3.0600
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1107
    Cell Significance Index: -1.3200
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.1115
    Cell Significance Index: -1.4300
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1176
    Cell Significance Index: -4.1200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1205
    Cell Significance Index: -3.9500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1228
    Cell Significance Index: -3.9100
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: -0.1298
    Cell Significance Index: -1.7500
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.1358
    Cell Significance Index: -1.9300
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.1369
    Cell Significance Index: -3.4200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1395
    Cell Significance Index: -2.0600
  • Cell Name: stromal cell of endometrium (CL0002255)
    Fold Change: -0.1427
    Cell Significance Index: -2.0300
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.1433
    Cell Significance Index: -4.2200
  • Cell Name: progenitor cell (CL0011026)
    Fold Change: -0.1450
    Cell Significance Index: -1.5400
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.1541
    Cell Significance Index: -3.1400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Function:** LMX1B acts as a transcription factor, regulating the expression of target genes involved in neuronal and hematopoietic development, cell differentiation, and survival. 2. **Cellular localization:** LMX1B is primarily found in the nucleus, where it binds to specific DNA sequences to regulate gene expression. 3. **Expression pattern:** LMX1B is expressed in a wide range of cell types, including neurons, hematopoietic stem cells, and cells of the blood system. 4. **Protein structure:** LMX1B contains a LIM domain, which is a characteristic feature of the LIM homeobox family of transcription factors. **Pathways and Functions:** LMX1B is involved in various biological pathways, including: 1. **Neuronal differentiation:** LMX1B regulates the expression of genes involved in neuronal differentiation, including those involved in the development of neurons and neural cells. 2. **Hematopoietic development:** LMX1B plays a critical role in the development and differentiation of hematopoietic cells, including erythrocytes, megakaryocytes, and other blood cells. 3. **Dorsal/ventral pattern formation:** LMX1B is involved in the regulation of gene expression during the development of the nervous system, including the formation of dorsal and ventral patterns. 4. **Metal ion binding:** LMX1B contains a metal ion-binding domain, which is thought to play a role in its function as a transcription factor. **Clinical Significance:** LMX1B has been implicated in various neurological and hematological disorders, including: 1. **Neurological disorders:** Mutations in LMX1B have been associated with neurological disorders, such as autism spectrum disorder and epilepsy. 2. **Hematological disorders:** LMX1B has been implicated in the development of hematological disorders, including leukemia and lymphoma. 3. **Cancer:** LMX1B has been found to be overexpressed in certain types of cancer, including ovarian and breast cancer. 4. **Developmental abnormalities:** LMX1B has been implicated in the development of developmental abnormalities, including craniofacial defects and limb abnormalities. In conclusion, LMX1B is a critical transcription factor that plays a pivotal role in the development and differentiation of various cell types, including neurons and hematopoietic cells. Its dysregulation has been implicated in various neurological and hematological disorders, highlighting the importance of further research into the function and regulation of this gene.

Genular Protein ID: 19951875

Symbol: LMX1B_HUMAN

Name: LIM homeobox transcription factor 1-beta

UniProtKB Accession Codes:

O60663 F8W7W6 O75463 Q5JU95 Q6ISC9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 11 Ensembl 3 GO 13 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 RefSeq 2 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 9618165

Title: Loss-of-function mutations in the LIM-homeodomain gene, LMX1B, in nail-patella syndrome.

PubMed ID: 9618165

DOI: 10.1093/hmg/7.7.1091

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9590287

Title: Mutations in LMX1B cause abnormal skeletal patterning and renal dysplasia in nail patella syndrome.

PubMed ID: 9590287

DOI: 10.1038/ng0598-47

PubMed ID: 23308148

Title: LMX1B is part of a transcriptional complex with PSPC1 and PSF.

PubMed ID: 23308148

DOI: 10.1371/journal.pone.0053122

PubMed ID: 9837817

Title: Mutation analysis of LMX1B gene in nail-patella syndrome patients.

PubMed ID: 9837817

DOI: 10.1086/302165

PubMed ID: 10571942

Title: Restricted distribution of loss-of-function mutations within the LMX1B genes of nail-patella syndrome patients.

PubMed ID: 10571942

DOI: 10.1002/(sici)1098-1004(199912)14:6<459::aid-humu3>3.0.co;2-9

PubMed ID: 11668639

Title: Twenty-two novel LMX1B mutations identified in nail patella syndrome (NPS) patients.

PubMed ID: 11668639

DOI: 10.1002/humu.1217.abs

PubMed ID: 23687361

Title: LMX1B mutations cause hereditary FSGS without extrarenal involvement.

PubMed ID: 23687361

DOI: 10.1681/asn.2013020171

PubMed ID: 24042019

Title: LMX1B mutation with residual transcriptional activity as a cause of isolated glomerulopathy.

PubMed ID: 24042019

DOI: 10.1093/ndt/gft359

PubMed ID: 26560070

Title: Clinical and histological findings of autosomal dominant renal-limited disease with LMX1B mutation.

PubMed ID: 26560070

DOI: 10.1111/nep.12666

PubMed ID: 28059119

Title: Dysregulation of WTI (-KTS) is associated with the kidney-specific effects of the LMX1B R246Q mutation.

PubMed ID: 28059119

DOI: 10.1038/srep39933

PubMed ID: 32791958

Title: Nail-patella-like renal disease masquerading as Fabry disease on kidney biopsy: a case report.

PubMed ID: 32791958

DOI: 10.1186/s12882-020-02012-3

PubMed ID: 32356190

Title: Myelin bodies in LMX1B-associated nephropathy: potential for misdiagnosis.

PubMed ID: 32356190

DOI: 10.1007/s00467-020-04564-w

Sequence Information:

  • Length: 402
  • Mass: 44917
  • Checksum: E59FC36C39C7C9A3
  • Sequence:
    • MDIATGPESL ERCFPRGQTD CAKMLDGIKM EEHALRPGPA TLGVLLGSDC PHPAVCEGCQ 
RPISDRFLMR VNESSWHEEC LQCAACQQAL TTSCYFRDRK LYCKQDYQQL FAAKCSGCME 
KIAPTEFVMR ALECVYHLGC FCCCVCERQL RKGDEFVLKE GQLLCKGDYE KEKDLLSSVS 
PDESDSVKSE DEDGDMKPAK GQGSQSKGSG DDGKDPRRPK RPRTILTTQQ RRAFKASFEV 
SSKPCRKVRE TLAAETGLSV RVVQVWFQNQ RAKMKKLARR HQQQQEQQNS QRLGQEVLSS 
RMEGMMASYT PLAPPQQQIV AMEQSPYGSS DPFQQGLTPP QMPGDHMNPY GNDSIFHDID 
SDTSLTSLSD CFLGSSDVGS LQARVGNPID RLYSMQSSYF AS

Genular Protein ID: 1744571347

Symbol: Q6ISE0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6ISE0

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 6 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 377
  • Mass: 42165
  • Checksum: 342C0EAD3206548A
  • Sequence:
    • DGIKMEEHAL RPGPATLGVL LGSDCPHPAV CEGCQRPISD RFLMRVNESS WHEECLQCAA 
CQQALTTSCY FRDRKLYCKQ DYQQLFAAKC SGCMEKIAPT EFVMRALECV YHLGCFCCCV 
CERQLRKGDE FVLKEGQLLC KGDYEKEKDL LSSVSPDESD SVKSEDEDGD MKPAKGQGSQ 
SKGSGDDGKD PRRPKRPRTI LTTQQRRAFK ASFEVSSKPC RKVRETLAAE TGLSVRVVQV 
WFQNQRAKMK KLARRHQQQQ EQQNSQRLGQ EVLSSRMEGM MASYTPLAPP QQQIVAMEQS 
PYGSSDPFQQ GLTPPQMPGD HMNPYGNDSI FHDIDSDTSL TSLSDCFLGS SDVGSLQARV 
GNPIDRLYSM QSSYFAS

Genular Protein ID: 3942536012

Symbol: B7ZLH2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7ZLH2

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 HOGENOM 1 InterPro 5 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 6 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 2 PharmGKB 1 ProteomicsDB 1 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SMR 1 SUPFAM 2 UCSC 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 383
  • Mass: 42572
  • Checksum: 28C51599518CF4FC
  • Sequence:
    • MLDGIKMEEH ALRPGPATLG VLLGSDCPHP AVCEGCQRPI SDRFLMRVNE SSWHEECLQC 
AACQQALTTS CYFRDRKLYC KQDYQQLFAA KCSGCMEKIA PTEFVMRALE CVYHLGCFCC 
CVCERQLRKG DEFVLKEGQL LCKGDYEKEK DLLSSVSPDE SDSVKSEDED GDMKPAKGQG 
SQSKGSGDDG KDPRRPKRPR TILTTQQRRA FKASFEVSSK PCRKVRETLA AETGLSVRVV 
QVWFQNQRAK MKKLARRHQQ QQEQQNSQRL GQGEPGPGQG LGQEVLSSRM EGMMASYTPL 
APPQQQIVAM EQSPYGSSDP FQQGLTPPQM PGNDSIFHDI DSDTSLTSLS DCFLGSSDVG 
SLQARVGNPI DRLYSMQSSY FAS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.