Details for: MUC3A

Gene ID: 4584

Symbol: MUC3A

Ensembl ID: ENSG00000169894

Description: mucin 3A, cell surface associated

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 8.4377
    Cell Significance Index: 182.8000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 7.1757
    Cell Significance Index: 206.7500
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 6.4475
    Cell Significance Index: 96.6100
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 6.3755
    Cell Significance Index: -3.0100
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 4.5006
    Cell Significance Index: -3.0200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 2.9820
    Cell Significance Index: 135.1700
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 2.8619
    Cell Significance Index: 34.5900
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 2.4715
    Cell Significance Index: 26.7900
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.8273
    Cell Significance Index: 18.9100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 1.5753
    Cell Significance Index: -4.2200
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 1.4374
    Cell Significance Index: 14.5000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 1.3778
    Cell Significance Index: 48.4200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.1931
    Cell Significance Index: 25.4100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.9730
    Cell Significance Index: 20.1900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.8524
    Cell Significance Index: 84.3200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.8100
    Cell Significance Index: 8.3900
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.7622
    Cell Significance Index: 12.8200
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.6558
    Cell Significance Index: 15.8900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.6300
    Cell Significance Index: 43.5700
  • Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
    Fold Change: 0.5799
    Cell Significance Index: 5.0700
  • Cell Name: lung goblet cell (CL1000143)
    Fold Change: 0.5465
    Cell Significance Index: 5.3700
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4260
    Cell Significance Index: 22.1300
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.3680
    Cell Significance Index: 5.2700
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 0.3631
    Cell Significance Index: 2.2400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.3146
    Cell Significance Index: 284.0800
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 0.2941
    Cell Significance Index: 2.2300
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 0.1907
    Cell Significance Index: 1.1800
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1560
    Cell Significance Index: 30.9600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1389
    Cell Significance Index: 26.4400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.1259
    Cell Significance Index: 2.1200
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.1183
    Cell Significance Index: 3.7900
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.1117
    Cell Significance Index: 1.8400
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 0.1115
    Cell Significance Index: 0.4200
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 0.0871
    Cell Significance Index: 0.7200
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 0.0397
    Cell Significance Index: 1.1700
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0287
    Cell Significance Index: 0.7800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.0149
    Cell Significance Index: 0.2200
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 0.0089
    Cell Significance Index: 0.0500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0045
    Cell Significance Index: 0.5100
  • Cell Name: stem cell (CL0000034)
    Fold Change: 0.0028
    Cell Significance Index: 0.0200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0025
    Cell Significance Index: 0.4600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0016
    Cell Significance Index: -2.9600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0020
    Cell Significance Index: -3.7400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0023
    Cell Significance Index: -3.5200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0026
    Cell Significance Index: -1.9400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0029
    Cell Significance Index: -3.9600
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0043
    Cell Significance Index: -2.6800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0044
    Cell Significance Index: -3.2800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0045
    Cell Significance Index: -2.4500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0047
    Cell Significance Index: -1.6800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0049
    Cell Significance Index: -3.6000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0054
    Cell Significance Index: -3.0200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0059
    Cell Significance Index: -3.7200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0062
    Cell Significance Index: -0.7600
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0064
    Cell Significance Index: -0.1600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0066
    Cell Significance Index: -1.1400
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: -0.0073
    Cell Significance Index: -0.0600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0077
    Cell Significance Index: -1.5400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0081
    Cell Significance Index: -3.6900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0127
    Cell Significance Index: -3.6400
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0146
    Cell Significance Index: -1.7000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0148
    Cell Significance Index: -1.5100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0157
    Cell Significance Index: -3.3000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0183
    Cell Significance Index: -2.3700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0224
    Cell Significance Index: -3.0800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0246
    Cell Significance Index: -3.5800
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: -0.0260
    Cell Significance Index: -0.2500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0309
    Cell Significance Index: -3.2200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0328
    Cell Significance Index: -3.8700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0377
    Cell Significance Index: -2.3100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0395
    Cell Significance Index: -2.6600
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: -0.0426
    Cell Significance Index: -0.3000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0433
    Cell Significance Index: -3.3300
  • Cell Name: mural cell (CL0008034)
    Fold Change: -0.0444
    Cell Significance Index: -0.5400
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0483
    Cell Significance Index: -0.5100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0523
    Cell Significance Index: -2.4400
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: -0.0528
    Cell Significance Index: -0.3100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0533
    Cell Significance Index: -3.9700
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0566
    Cell Significance Index: -3.4800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0599
    Cell Significance Index: -1.6700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0684
    Cell Significance Index: -3.8400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0687
    Cell Significance Index: -3.2300
  • Cell Name: colonocyte (CL1000347)
    Fold Change: -0.0688
    Cell Significance Index: -0.4300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0707
    Cell Significance Index: -3.7100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0760
    Cell Significance Index: -3.3600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0802
    Cell Significance Index: -4.0600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0871
    Cell Significance Index: -3.0500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0871
    Cell Significance Index: -3.3000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0959
    Cell Significance Index: -3.1400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0961
    Cell Significance Index: -3.0600
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0972
    Cell Significance Index: -2.7800
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0977
    Cell Significance Index: -2.8700
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0999
    Cell Significance Index: -3.1600
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.1008
    Cell Significance Index: -3.7000
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.1010
    Cell Significance Index: -4.1400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.1015
    Cell Significance Index: -2.7100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1038
    Cell Significance Index: -2.5900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1088
    Cell Significance Index: -1.6400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1088
    Cell Significance Index: -2.8600
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.1103
    Cell Significance Index: -1.5300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** MUC3A is a member of the mucin family, which comprises a diverse group of proteins that play crucial roles in maintaining the integrity of epithelial surfaces. MUC3A is distinct from other mucins due to its unique cell surface localization and association with the C-type lectin receptor (CLRs) pathway. This characteristic enables MUC3A to interact with various immune cells, modulating their activities and influencing the immune response. **Pathways and Functions:** MUC3A's involvement in the immune system is mediated through its interaction with CLRs, such as Dectin-2, which is a pattern recognition receptor that recognizes carbohydrate structures on pathogens. This interaction triggers a signaling cascade that activates immune cells, including macrophages and dendritic cells, promoting the production of pro-inflammatory cytokines and chemokines. Furthermore, MUC3A's association with the Golgi lumen and its role in terminating O-linked glycosylation of mucins suggest its involvement in protein modification and glycosylation processes. **Clinical Significance:** MUC3A's expression in various tissues, including the colon, prostate, lung, and intestine, highlights its importance in maintaining epithelial homeostasis. Dysregulation of MUC3A has been implicated in several diseases, including inflammatory bowel disease (IBD), where it contributes to the pathogenesis of colitis by promoting inflammation and recruiting immune cells to the site of injury. Additionally, MUC3A's involvement in the innate immune response suggests its potential role in the development of vaccines and therapeutic strategies targeting mucosal surfaces. **Significantly Expressed Cells:** The expression of MUC3A in various cell types, including colon epithelial cells, luminal cells of prostate epithelium, enterocytes of colon and intestine, lung goblet cells, and intestinal crypt stem cells, underscores its widespread role in maintaining epithelial integrity and modulating the immune response. **Proteins:** The two protein entries for MUC3A, MUC3A_HUMAN and Q9H3Q6_HUMAN, provide a glimpse into the structural and functional characteristics of this mucin. Further studies are necessary to fully elucidate the protein structure and its interactions with other molecules. In conclusion, MUC3A is a multifaceted protein that plays a crucial role in the innate immune system, particularly in the context of mucosal surfaces. Its involvement in signaling pathways, protein modification, and glycosylation processes underscores its importance in maintaining epithelial homeostasis. Further research is necessary to fully elucidate the mechanisms by which MUC3A regulates the immune response and its clinical significance in various diseases.

Genular Protein ID: 72370368

Symbol: MUC3A_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q02505 A6NP22 O14650 O14651 O43418 O43421 Q02506 Q6W763 Q9H3Q7 Q9UKW9 Q9UN93 Q9UN94 Q9UN95

Database IDs:

AGR 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 2 ExpressionAtlas 1 GO 6 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MEROPS 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PIR 2 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pharos 1 PhosphoSitePlus 1 Proteomes 1 RNAct 1 Reactome 6 RefSeq 1 SMART 2 STRING 1 SUPFAM 1 SignaLink 1 UCSC 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12853948

Title: The DNA sequence of human chromosome 7.

PubMed ID: 12853948

DOI: 10.1038/nature01782

PubMed ID: 12958310

Title: Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus.

PubMed ID: 12958310

DOI: 10.1074/jbc.m305769200

PubMed ID: 9334251

Title: MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region.

PubMed ID: 9334251

DOI: 10.1074/jbc.272.42.26678

PubMed ID: 10512748

Title: Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.

PubMed ID: 10512748

DOI: 10.1006/bbrc.1999.1466

PubMed ID: 11289722

Title: Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease.

PubMed ID: 11289722

DOI: 10.1007/s100380170118

PubMed ID: 10405327

Title: The MUC3 gene encodes a transmembrane mucin and is alternatively spliced.

PubMed ID: 10405327

DOI: 10.1006/bbrc.1999.1001

PubMed ID: 2393399

Title: Molecular cloning of cDNAs derived from a novel human intestinal mucin gene.

PubMed ID: 2393399

DOI: 10.1016/0006-291x(90)91408-k

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

Sequence Information:

  • Length: 3323
  • Mass: 345127
  • Checksum: 8C6E21ADD26637EF
  • Sequence:
    • MQLLGLLGLL WMLKASPWAT GTLSTATSIS QVPFPRAEAA SAVLSNSPHS RDLAGWPLGV 
PQLASPAPGH RENAPMTLTT SPHDTLISET LLNSPVSSNT STTPTSKFAF KVETTPPTVL 
VYSATTECVY PTSFIITISH PTSICVTTTQ VAFTSSYTST PVTQKPVTTV TSTYSMTTTE 
KGTSAMTSSP STTTARETPI VTVTPSSVSA TDTTFHTTIS STTRTTERTP LPTGSIHTTT 
SPTPVFTTLK TAVTSTSPIT SSITSTNTVT SMTTTASQPT ATNTLSSPTR TILSSTPVLS 
TETITSGITN TTPLSTLVTT LPTTISRSTP TSETTYTTSP TSTVTDSTTK IAYSTSMTGT 
LSTETSLPPT SSSLPTTETA TTPMTNLVTT TTEISSHSTP SFSSSTIYST VSTSTTAISS 
LPPTSGTMVT STTMTPSSLS TDIPFTTPTT ITHHSVGSTG FLTTATDLTS TFTVSSSSAM 
STSVIPSSPS IQNTETSSLV SMTSATTPNV RPTFVSTLST PTSSLLTTFP ATYSFSSSMS 
ASSAGTTHTE SISSPPASTS TLHTTAESTL APTTTTSFTT STTMEPPSTT AATTGTGQTT 
FTSSTATFPE TTTPTPTTDM STESLTTAMT SPPITSSVTS TNTVTSMTTT TSPPTTTNSF 
TSLTSMPLSS TPVPSTEVVT SGTINTIPPS ILVTTLPTPN ASSMTTSETT YPNSPTGPGT 
NSTTEITYPT TMTETSSTAT SLPPTSPLVS TAKTAKTPTT NLVTTTTKTT SHSTTSFTSS 
TVYSTASTYT TAITSVPTTL GTMVTSTSMI SSTVSTGIPT SQPTTITPSS VGISGSLPMM 
TDLTSVYTVS NMSARPTTVI PSSPTVQNTE ISISVSMTSA TTPSGGPTFT STENTPTRSL 
LTSFPMTHSF SSSMSESSAG TTHTESISSP RGTTSTLHTT VESTPSPTTT TSFTTSTMME 
PPSSTVSTTG RGQTTFPSST ATFPETTTLT PTTDISTVSL TTAMTSPPPV SSSITPTNTM 
TSMRTTTYWP TATNTLSPLT SSILSSTPVP STEMITSHTT NTTPLSTLVT TLLTTITRST 
PTSETTYPTS PTSIVSDSTT EITYSTSITG TLSTATTLPP TSSSLPTTET ATMTPTTTLI 
TTTPNTTSLS TPSFTSSTIY STVSTSTTAI SSASPTSGTM VTSTTMTPSS LSTDTPSTTP 
TTITYPSVGS TGFLTTATDL TSTFTVSSSS AMSTSVIPSS PSIQNTETSS LVSMTSATTP 
SLRPTITSTD STLTSSLLTT FPSTYSFSSS MSASSAGTTH TETISSLPAS TNTIHTTAES 
ALAPTTTTSF TTSPTMEPPS TTVATTGTGQ TTFPSSTATF LETTTLTPTT DFSTESLTTA 
MTSTPPITSS ITPTDTMTSM RTTTSWPTAT NTLSPLTSSI LSSTPVPSTE VTTSHTTNTN 
PVSTLVTTLP ITITRSTLTS ETAYPSSPTS TVTESTTEIT YPTTMTETSS TATSLPPTSS 
LVSTAETAKT PTTNLVTTTT KTTSHSTTSF TSSTIYSTAS TPTTAITSVP TTLGTMVTST 
SMIPSTVSTG IPTSQPTTIT PSSVGISGSL PMMTDLTSVY TVSSMSARPT SVIPSSPTVQ 
NTETSIFVSM MSATTPSGGP TFTSTENTPT RSLLTSFPVT HSFSSSMSAS SVGTTHTQSI 
SSPPAITSTL HTTAESTPSP TTTMSFTTFT KMETPSSTVA TTGTGQTTFT SSTATSPKTT 
TLTPTSDIST GSFKTAVSST PPITSSITST YTVTSMTTTT PLGPTATNTL PSFTSSVSSS 
TPVPSTEAIT SGTTNTTPLS TLVTTFSNSD TSSTPTSETT YPTSLTSALT DSTTRTTYST 
NMTGTLSTVT SLRPTSSSLL TTVTATVPTT NLVTTTTKIT SHSTPSFTSS IATTETPSHS 
TPRFTSSITT TETPSHSTPR FTSSITNTKT TSHSSPSFTS SITTTETTSH NTPSLTSSIT 
TTKTTSHSTP SYTSLITTTT TTSHSTPSFT SSITTTETTS HNTPSLTSSI TTTETTSHST 
PSFTSSITTE TTSHSTPSFT SLITITEITS HSTLSYTTSI TTTETPSHST LSFTSSITTT 
ETTSHSTPSF TSSITTSEMP SHSTPSFTSS ITTTENATHS TPNFTSSITT TETTSHSTPS 
FTSLITTTET TSHRWGTTET TSYSTPSFTS SNTITETTSH STPSYITSIT TTETPSSSTP 
SFSSSITTTE TTSHSTPGFT SSITTTETTS HSTPSFTSSI TTTETTSHDT PSFTSSITTS 
ETPSHSTPSS TSLITTTKTT SHSTPSFTSS ITTTETTSHS AHSFTSSITT TETTSHNTRS 
FTSSITTTET NSHSTTSFTS SITTTETTSH STPSFSSSIT TTETPLHSTP GLTSWVTTTK 
TTSHITPGLT SSITTTETTS HSTPGFTSSI TTTETTSEST PSLSSSTIYS TVSTSTTAIT 
SHFTTSETAV TPTPVTPSSL STDIPTTSLR TLTPSSVGTS TSLTTTTDFP SIPTDISTLP 
TRTHIISSSP SIQSTETSSL VGTTSPTMST VRMTLRITEN TPISSFSTSI VVIPETPTQT 
PPVLTSATGT QTSPAPTTVT FGSTDSSTST LHTLTPSTAL STIVSTSQVP IPSTHSSTLQ 
TTPSTPSLQT SLTSTSEFTT ESFTRGSTST NAILTSFSTI IWSSTPTIIM SSSPSSASIT 
PVFSTTIHSV PSSPYIFSTE NVGSASITGF PSLSSSATTS TSSTSSSLTT ALTEITPFSY 
ISLPSTTPCP GTITITIVPA SPTDPCVEMD PSTEATSPPT TPLTVFPFTT EMVTCPTSIS 
IQTTLTTYMD TSSMMPESES SISPNASSST GTGTVPTNTV FTSTRLPTSE TWLSNSSVIP 
LPLPGVSTIP LTMKPSSSLP TILRTSSKST HPSPPTTRTS ETPVATTQTP TTLTSRRTTR 
ITSQMTTQST LTTTAGTCDN GGTWEQGQCA CLPGFSGDRC QLQTRCQNGG QWDGLKCQCP 
STFYGSSCEF AVEQVDLDVV ETEVGMEVSV DQQFSPDLND NTSQAYRDFN KTFWNQMQKI 
FADMQGFTFK GVEILSLRNG SIVVDYLVLL EMPFSPQLES EYEQVKTTLK EGLQNASQDV 
NSCQDSQTLC FKPDSIKVNN NSKTELTPAA ICRRAAPTGY EEFYFPLVEA TRLRCVTKCT 
SGVDNAIDCH QGQCVLETSG PTCRCYSTDT HWFSGPRCEV AVHWRALVGG LTAGAALLVL 
LLLALGVRAV RSGWWGGQRR GRSWDQDRKW FETWDEEVVG TFSNWGFEDD GTDKDTNFYV 
ALENVDTTMK VHIKRPEMTS SSV

Genular Protein ID: 4117297913

Symbol: Q9H3Q6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9H3Q6

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 2 InterPro 5 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 RefSeq 1 SAM 2 SMART 2 SUPFAM 1

Citations:

PubMed ID: 11289722

Title: Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease.

PubMed ID: 11289722

DOI: 10.1007/s100380170118

Sequence Information:

  • Length: 877
  • Mass: 93721
  • Checksum: 09EE5E86BC838DFA
  • Sequence:
    • TIYSTVSTST TAITSHFTTS ETAVTPTPVT PSSLSTDIPT TSLRTLTPSS VGTSTSLTTT 
TDFPSIPTDI STLPTRTHII SSSPSIQSTE TSSLVGTTSP TMSTVRMTLR ITENTPISSF 
STSIVVIPET PTQTPPVLTS ATGTQTSPAP TTVTFGSTDS STSTLHTLTP STALSTIVST 
SQVPIPSTHS STLQTTPSTP SLQTSLTSTS EFTTESFTRG STSTNAILTS FSTIIWSSTP 
TIIMSSSPSS ASITPVFSTT IHSVPSSPYI FSTENVGSAS ITGFPSLSSS ATTSTSSTSS 
SLTTALTEIT PFSYISLPST TPCPGTITIT IVPASPTDPC VEMDPSTEAT SPPTTPLTVF 
PFTTEMVTCP TSISIQTTLT TYMDTSSMMP ESESSISPNA SSSTGTGTVP TNTVFTSTRL 
PTSETWLSNS SVIPLPLPGV STIPLTMKPS SSLPTILRTS SKSTHPSPPT TRTSETPVAT 
TQTPTTLTSR RTTRITSQMT TQSTLTTTAG TCDNGGTWEQ GQCACLPGFS GDRCQLQTRC 
QNGGQWDGLK CQCPSTFYGS SCEFAVEQVD LDVVETEVGM EVSVDQQFSP DLNDNTSQAY 
RDFNKTFWNQ MQKIFADMQG FTFKGVEILS LRNGSIVVDY LVLLEMPFSP QLESEYEQVK 
TTLKEGLQNA SQDVNSCQDS QTLCFKPDSI KVNNNSKTEL TPAAICRRAA PTGYEEFYFP 
LVEATRLRCV TKCTSGVDNA IDCHQGQCVL ETSGPTCRCY STDTHWFSGP RCEVAVHWRA 
LVGGLTAGAA LLVLLLLALG VRAVRSGWWG GQRRGRSWDQ DRKWFETWDE EVVGTFSNWG 
FEDDGTDKDT NFYVALENVD TTMKVHIKRP EMTSSSV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.