Details for: NAGLU

Gene ID: 4669

Symbol: NAGLU

Ensembl ID: ENSG00000108784

Description: N-acetyl-alpha-glucosaminidase

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 106.8500
    Cell Significance Index: -16.6200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 64.9928
    Cell Significance Index: -16.4900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 13.6907
    Cell Significance Index: -16.8800
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 6.0585
    Cell Significance Index: -16.2300
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 4.5353
    Cell Significance Index: -13.9300
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 4.2992
    Cell Significance Index: -16.9700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.3536
    Cell Significance Index: 63.0700
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 1.4883
    Cell Significance Index: 69.3900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.1963
    Cell Significance Index: 71.8200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 1.1451
    Cell Significance Index: 133.4500
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 1.1201
    Cell Significance Index: 17.9700
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.0325
    Cell Significance Index: 112.3000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.8173
    Cell Significance Index: 132.9300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.7695
    Cell Significance Index: 16.6700
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.6133
    Cell Significance Index: 9.7300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.6127
    Cell Significance Index: 121.6000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.5806
    Cell Significance Index: 40.1500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4917
    Cell Significance Index: 13.7400
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: 0.4452
    Cell Significance Index: 3.7400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.4343
    Cell Significance Index: 22.5600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.4124
    Cell Significance Index: 56.6400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.3922
    Cell Significance Index: 70.7000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.2876
    Cell Significance Index: 14.5300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.2744
    Cell Significance Index: 33.7400
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.2737
    Cell Significance Index: 2.5200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.2620
    Cell Significance Index: 7.5500
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.2243
    Cell Significance Index: 5.9900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.2192
    Cell Significance Index: 21.6800
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.2166
    Cell Significance Index: 3.0400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.2153
    Cell Significance Index: 9.7600
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2141
    Cell Significance Index: 116.9400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.1478
    Cell Significance Index: 25.2400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1400
    Cell Significance Index: 3.5000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1101
    Cell Significance Index: 99.3800
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1022
    Cell Significance Index: 20.5100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 0.0980
    Cell Significance Index: 2.8100
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0972
    Cell Significance Index: 42.9800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0923
    Cell Significance Index: 7.0900
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.0895
    Cell Significance Index: 1.2900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0707
    Cell Significance Index: 13.4500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0645
    Cell Significance Index: 23.1200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.0643
    Cell Significance Index: 3.0200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0630
    Cell Significance Index: 2.2200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 0.0628
    Cell Significance Index: 8.0500
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.0618
    Cell Significance Index: 0.8900
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.0588
    Cell Significance Index: 0.5000
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.0433
    Cell Significance Index: 1.0000
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0155
    Cell Significance Index: 0.3300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0138
    Cell Significance Index: 0.8900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0079
    Cell Significance Index: 5.7800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0014
    Cell Significance Index: -0.0300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0024
    Cell Significance Index: -1.8500
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0037
    Cell Significance Index: -0.0300
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: -0.0046
    Cell Significance Index: -0.0300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0070
    Cell Significance Index: -13.2400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0093
    Cell Significance Index: -0.6600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0104
    Cell Significance Index: -19.1300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0114
    Cell Significance Index: -0.8500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0128
    Cell Significance Index: -1.6600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0133
    Cell Significance Index: -20.5000
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0158
    Cell Significance Index: -21.5000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0165
    Cell Significance Index: -12.2500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0226
    Cell Significance Index: -14.3800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0261
    Cell Significance Index: -2.6700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0265
    Cell Significance Index: -14.9700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0281
    Cell Significance Index: -17.5400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0358
    Cell Significance Index: -10.3100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0365
    Cell Significance Index: -16.5600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0532
    Cell Significance Index: -3.2700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0544
    Cell Significance Index: -3.0500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0642
    Cell Significance Index: -1.6500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0714
    Cell Significance Index: -8.1800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0728
    Cell Significance Index: -1.4200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0833
    Cell Significance Index: -9.8200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0834
    Cell Significance Index: -2.2700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0854
    Cell Significance Index: -17.9900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1054
    Cell Significance Index: -15.3200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1099
    Cell Significance Index: -6.7400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1368
    Cell Significance Index: -4.3800
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1612
    Cell Significance Index: -16.7800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1745
    Cell Significance Index: -13.8200
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1948
    Cell Significance Index: -12.2800
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.2027
    Cell Significance Index: -3.4200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2073
    Cell Significance Index: -5.4500
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2238
    Cell Significance Index: -15.0500
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2434
    Cell Significance Index: -6.5100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.2501
    Cell Significance Index: -4.1900
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.2644
    Cell Significance Index: -5.7900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.2791
    Cell Significance Index: -4.1200
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2798
    Cell Significance Index: -14.6900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2807
    Cell Significance Index: -3.8300
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.2908
    Cell Significance Index: -1.9700
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.3123
    Cell Significance Index: -4.6100
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.3130
    Cell Significance Index: -3.2400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.3531
    Cell Significance Index: -15.6200
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.3593
    Cell Significance Index: -4.4800
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.3685
    Cell Significance Index: -4.6400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.3712
    Cell Significance Index: -12.9000
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: -0.3856
    Cell Significance Index: -3.9900
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.3872
    Cell Significance Index: -4.7900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Enzymatic activity**: NAGLU catalyzes the hydrolysis of N-acetylglucosamine (GlcNAc) from heparan sulfate proteoglycans and glycosaminoglycans, resulting in the release of GlcNAc and desulfated HSPGs. 2. **Subcellular localization**: NAGLU is primarily localized to the lysosome and Golgi apparatus, where it regulates HSPG and GAG degradation. 3. **Cellular expression**: NAGLU is expressed in various cell types, including immature innate lymphoid cells, pancreatic A cells, and cardiac muscle myoblasts, highlighting its importance in different cellular processes. 4. **Disease association**: Mutations in the NAGLU gene have been linked to Mucopolysaccharidoses (MPS), a group of lysosomal storage disorders characterized by the accumulation of HSPGs and GAGs. **Pathways and Functions** 1. **HSPG and GAG degradation**: NAGLU plays a critical role in the degradation of HSPGs and GAGs, which are essential for maintaining cellular homeostasis and regulating various cellular processes. 2. **Cell signaling**: NAGLU influences cell signaling pathways, including the Wnt/β-catenin and Notch signaling pathways, by regulating the availability of HSPGs and GAGs. 3. **Cell adhesion**: NAGLU contributes to cell adhesion by regulating the expression of HSPGs and GAGs, which are essential for maintaining cell-cell interactions and tissue architecture. 4. **Immune regulation**: NAGLU is involved in immune regulation, as it influences the function of immune cells, including innate lymphoid cells and microglia. **Clinical Significance** 1. **Mucopolysaccharidoses**: Mutations in the NAGLU gene are associated with MPS type I (Sanfilippo syndrome B), a severe lysosomal storage disorder characterized by the accumulation of HSPGs and GAGs. 2. **Cancer**: NAGLU has been implicated in cancer, as it influences the expression of HSPGs and GAGs, which can impact tumor progression and metastasis. 3. **Neurological disorders**: NAGLU has been linked to various neurological disorders, including Alzheimer's disease and Parkinson's disease, as it influences the regulation of HSPGs and GAGs in the brain. 4. **Cardiovascular disease**: NAGLU may play a role in cardiovascular disease, as it influences the regulation of HSPGs and GAGs in the cardiovascular system. In conclusion, NAGLU is a crucial enzyme involved in the degradation of HSPGs and GAGs, regulating various cellular processes, and influencing disease progression. Further research is necessary to fully understand the functions and clinical significance of NAGLU in different diseases.

Genular Protein ID: 2682412388

Symbol: ANAG_HUMAN

Name: Alpha-N-acetylglucosaminidase

UniProtKB Accession Codes:

P54802

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CAZy 1 CCDS 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 EC 2 EMBL 6 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 54 Gene3D 3 GeneCards 1 GeneReviews 1 GeneTree 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 2 RefSeq 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8650226

Title: The molecular basis of Sanfilippo syndrome type B.

PubMed ID: 8650226

DOI: 10.1073/pnas.93.12.6101

PubMed ID: 8776591

Title: Cloning and expression of the gene involved in Sanfilippo B syndrome (mucopolysaccharidosis III B).

PubMed ID: 8776591

DOI: 10.1093/hmg/5.6.771

PubMed ID: 8703123

Title: Molecular dissection of a cosmid from a gene-rich region in 17q21 and characterization of a candidate gene for alpha-N-acetylglucosaminidase with two cDNA isoforms.

PubMed ID: 8703123

DOI: 10.1007/s003359900206

PubMed ID: 16625196

Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.

PubMed ID: 16625196

DOI: 10.1038/nature04689

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 25818867

Title: Adult-onset painful axonal polyneuropathy caused by a dominant NAGLU mutation.

PubMed ID: 25818867

DOI: 10.1093/brain/awv074

PubMed ID: 9443875

Title: Genotype-phenotype correspondence in Sanfilippo syndrome type B.

PubMed ID: 9443875

DOI: 10.1086/301682

PubMed ID: 9443878

Title: NAGLU mutations underlying Sanfilippo syndrome type B.

PubMed ID: 9443878

DOI: 10.1086/301685

PubMed ID: 9832037

Title: Identification of 12 novel mutations in the alpha-N-acetylglucosaminidase gene in 14 patients with Sanfilippo syndrome type B (mucopolysaccharidosis type IIIB).

PubMed ID: 9832037

DOI: 10.1136/jmg.35.11.910

PubMed ID: 9950362

Title: Mucopolysaccharidosis type IIIB (Sanfilippo B): identification of 18 novel alpha-N-acetylglucosaminidase gene mutations.

PubMed ID: 9950362

PubMed ID: 10094189

Title: Sanfilippo type B syndrome (mucopolysaccharidosis III B): allelic heterogeneity corresponds to the wide spectrum of clinical phenotypes.

PubMed ID: 10094189

DOI: 10.1038/sj.ejhg.5200242

PubMed ID: 11068184

Title: Mucopolysaccharidosis type IIIB: characterisation and expression of wild-type and mutant recombinant alpha-N-acetylglucosaminidase and relationship with sanfilippo phenotype in an attenuated patient.

PubMed ID: 11068184

DOI: 10.1016/s0925-4439(00)00066-1

PubMed ID: 11153910

Title: Molecular defects in the alpha-N-acetylglucosaminidase gene in Italian Sanfilippo type B patients.

PubMed ID: 11153910

DOI: 10.1007/s004390000429

PubMed ID: 11286389

Title: Allelic heterogeneity in Spanish patients with Sanfilippo disease type B. Identification of eight new mutations.

PubMed ID: 11286389

DOI: 10.1023/a:1005627311402

PubMed ID: 11793481

Title: Sanfilippo syndrome in Turkey: identification of novel mutations in subtypes A and B.

PubMed ID: 11793481

DOI: 10.1002/humu.9009

PubMed ID: 12202988

Title: Molecular analysis of the alpha-N-acetylglucosaminidase gene in seven Japanese patients from six unrelated families with mucopolysaccharidosis IIIB (Sanfilippo type B), including two novel mutations.

PubMed ID: 12202988

DOI: 10.1007/s100380200070

PubMed ID: 11836372

Title: Identification and characterisation of mutations underlying Sanfilippo syndrome type B (mucopolysaccharidosis type IIIB).

PubMed ID: 11836372

DOI: 10.1136/jmg.39.2.e3

PubMed ID: 14984474

Title: Sanfilippo B syndrome: molecular defects in Greek patients.

PubMed ID: 14984474

DOI: 10.1111/j.0009-9163.2004.00210.x

PubMed ID: 15933803

Title: Sanfilippo type B syndrome: five patients with an R565P homozygous mutation in the alpha-N-acetylglucosaminidase gene from the Okinawa islands in Japan.

PubMed ID: 15933803

DOI: 10.1007/s10038-005-0258-4

PubMed ID: 16151907

Title: Molecular defects in Sanfilippo syndrome type B (mucopolysaccharidosis IIIB).

PubMed ID: 16151907

DOI: 10.1007/s10545-005-0093-y

PubMed ID: 28101780

Title: Update of the spectrum of mucopolysaccharidoses type III in Tunisia: identification of three novel mutations and in silico structural analysis of the missense mutations.

PubMed ID: 28101780

DOI: 10.1007/s12519-017-0005-x

Sequence Information:

  • Length: 743
  • Mass: 82266
  • Checksum: 6D8D6A42C7BA7CF3
  • Sequence:
    • MEAVAVAAAV GVLLLAGAGG AAGDEAREAA AVRALVARLL GPGPAADFSV SVERALAAKP 
GLDTYSLGGG GAARVRVRGS TGVAAAAGLH RYLRDFCGCH VAWSGSQLRL PRPLPAVPGE 
LTEATPNRYR YYQNVCTQSY SFVWWDWARW EREIDWMALN GINLALAWSG QEAIWQRVYL 
ALGLTQAEIN EFFTGPAFLA WGRMGNLHTW DGPLPPSWHI KQLYLQHRVL DQMRSFGMTP 
VLPAFAGHVP EAVTRVFPQV NVTKMGSWGH FNCSYSCSFL LAPEDPIFPI IGSLFLRELI 
KEFGTDHIYG ADTFNEMQPP SSEPSYLAAA TTAVYEAMTA VDTEAVWLLQ GWLFQHQPQF 
WGPAQIRAVL GAVPRGRLLV LDLFAESQPV YTRTASFQGQ PFIWCMLHNF GGNHGLFGAL 
EAVNGGPEAA RLFPNSTMVG TGMAPEGISQ NEVVYSLMAE LGWRKDPVPD LAAWVTSFAA 
RRYGVSHPDA GAAWRLLLRS VYNCSGEACR GHNRSPLVRR PSLQMNTSIW YNRSDVFEAW 
RLLLTSAPSL ATSPAFRYDL LDLTRQAVQE LVSLYYEEAR SAYLSKELAS LLRAGGVLAY 
ELLPALDEVL ASDSRFLLGS WLEQARAAAV SEAEADFYEQ NSRYQLTLWG PEGNILDYAN 
KQLAGLVANY YTPRWRLFLE ALVDSVAQGI PFQQHQFDKN VFQLEQAFVL SKQRYPSQPR 
GDTVDLAKKI FLKYYPRWVA GSW

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.