Details for: F11R

Gene ID: 50848

Symbol: F11R

Ensembl ID: ENSG00000158769

Description: F11 receptor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 106.9142
    Cell Significance Index: -16.6300
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 61.6220
    Cell Significance Index: -15.6300
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 44.7144
    Cell Significance Index: -18.4200
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 41.8454
    Cell Significance Index: -17.0000
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 36.5485
    Cell Significance Index: -18.8000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 17.8058
    Cell Significance Index: -17.0000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 14.2098
    Cell Significance Index: -17.5200
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 7.1822
    Cell Significance Index: -19.2400
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 5.5887
    Cell Significance Index: 152.1200
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 4.6890
    Cell Significance Index: 243.5800
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.2904
    Cell Significance Index: -9.3900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 2.7162
    Cell Significance Index: 441.7700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 2.0448
    Cell Significance Index: 44.3000
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.0139
    Cell Significance Index: 18.5500
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.9969
    Cell Significance Index: 217.2000
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 1.9754
    Cell Significance Index: 29.6000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 1.9319
    Cell Significance Index: 237.5400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 1.8932
    Cell Significance Index: 341.2800
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 1.8666
    Cell Significance Index: 18.8300
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 1.7142
    Cell Significance Index: 17.7400
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 1.6667
    Cell Significance Index: 10.3200
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 1.5729
    Cell Significance Index: 9.6800
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: 1.3841
    Cell Significance Index: 8.6000
  • Cell Name: peg cell (CL4033014)
    Fold Change: 1.3487
    Cell Significance Index: 31.1600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 1.2871
    Cell Significance Index: 95.9300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 1.2708
    Cell Significance Index: 18.0900
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.2410
    Cell Significance Index: 35.7600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.1825
    Cell Significance Index: 53.6000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.8406
    Cell Significance Index: 9.5500
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.7298
    Cell Significance Index: 94.2900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.7221
    Cell Significance Index: 394.3600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.6851
    Cell Significance Index: 14.5900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.6181
    Cell Significance Index: 28.8200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5521
    Cell Significance Index: 498.4900
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.5026
    Cell Significance Index: 222.1900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.4789
    Cell Significance Index: 13.3900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4533
    Cell Significance Index: 89.9700
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 0.4404
    Cell Significance Index: 2.6000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.4275
    Cell Significance Index: 20.0900
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.3616
    Cell Significance Index: 61.7500
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.3452
    Cell Significance Index: 215.5800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3449
    Cell Significance Index: 65.6400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.3435
    Cell Significance Index: 33.9800
  • Cell Name: prostate gland microvascular endothelial cell (CL2000059)
    Fold Change: 0.3411
    Cell Significance Index: 2.4500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.3271
    Cell Significance Index: 23.1400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1424
    Cell Significance Index: 5.0100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.1115
    Cell Significance Index: 22.3700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 0.0689
    Cell Significance Index: 1.1600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0483
    Cell Significance Index: 6.6300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0473
    Cell Significance Index: 35.8300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0348
    Cell Significance Index: 12.4900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.0343
    Cell Significance Index: 3.9200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0283
    Cell Significance Index: 19.6000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0200
    Cell Significance Index: 0.6400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 0.0082
    Cell Significance Index: 0.2200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.0012
    Cell Significance Index: 0.0700
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0001
    Cell Significance Index: -0.2000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0014
    Cell Significance Index: -1.0700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0067
    Cell Significance Index: -4.9200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0092
    Cell Significance Index: -16.9000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0111
    Cell Significance Index: -17.1200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0135
    Cell Significance Index: -18.3400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0163
    Cell Significance Index: -10.3500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0176
    Cell Significance Index: -9.9200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0302
    Cell Significance Index: -3.0900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0359
    Cell Significance Index: -7.5600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0434
    Cell Significance Index: -19.7100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0496
    Cell Significance Index: -5.6800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0499
    Cell Significance Index: -7.2500
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0513
    Cell Significance Index: -0.3100
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0520
    Cell Significance Index: -0.7100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0644
    Cell Significance Index: -18.5400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0888
    Cell Significance Index: -11.3900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0920
    Cell Significance Index: -0.7500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1166
    Cell Significance Index: -13.5900
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.1274
    Cell Significance Index: -1.8800
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.1276
    Cell Significance Index: -1.7900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1364
    Cell Significance Index: -3.4100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1403
    Cell Significance Index: -16.5500
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.1423
    Cell Significance Index: -4.5000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1485
    Cell Significance Index: -9.1300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.1541
    Cell Significance Index: -1.6000
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1582
    Cell Significance Index: -8.2400
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1668
    Cell Significance Index: -17.3700
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2119
    Cell Significance Index: -7.7800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2167
    Cell Significance Index: -17.1600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2204
    Cell Significance Index: -16.9200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2254
    Cell Significance Index: -9.9700
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: -0.2307
    Cell Significance Index: -2.3800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.2597
    Cell Significance Index: -17.4600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.2690
    Cell Significance Index: -16.5000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2691
    Cell Significance Index: -16.9600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2748
    Cell Significance Index: -15.4200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2753
    Cell Significance Index: -10.4300
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.2771
    Cell Significance Index: -4.6600
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.2934
    Cell Significance Index: -4.8400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.2982
    Cell Significance Index: -7.8400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2991
    Cell Significance Index: -8.0000
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.3132
    Cell Significance Index: -5.5400
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.3141
    Cell Significance Index: -5.8100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The F11 receptor is a transmembrane glycoprotein that belongs to the JAM family, characterized by its unique structure and ligand-binding properties. Key features of the F11 receptor include: 1. **Cell-cell adhesion**: The F11 receptor is involved in maintaining cell-cell adhesion, particularly in epithelial and endothelial tissues, by interacting with other adhesion molecules, such as cadherins and integrins. 2. **Tight junction formation**: The receptor plays a crucial role in the formation and maintenance of tight junctions, which are essential for maintaining the integrity of epithelial and endothelial barriers. 3. **Cell migration and differentiation**: The F11 receptor is involved in regulating cell migration and differentiation, particularly in hematopoietic cells, where it influences the development and function of immune cells. 4. **Signaling pathways**: The receptor is activated by various signaling molecules, including TGF-β, which triggers downstream signaling pathways that regulate cellular processes, such as cell adhesion, migration, and differentiation. **Pathways and Functions** The F11 receptor is involved in various signaling pathways, including: 1. **TGF-β signaling**: The receptor is activated by TGF-β, which triggers downstream signaling pathways that regulate cellular processes, such as cell adhesion, migration, and differentiation. 2. **Cadherin binding**: The receptor interacts with cadherins, which are essential for maintaining cell-cell adhesion in epithelial and endothelial tissues. 3. **Integrin binding**: The receptor interacts with integrins, which are involved in regulating cell migration and differentiation. 4. **Rho protein signaling**: The receptor is activated by TGF-β, which triggers downstream signaling pathways that regulate Rho protein activity, which in turn regulates actin cytoskeleton organization and cell shape. **Clinical Significance** The F11 receptor is involved in various diseases, including: 1. **Immune disorders**: The receptor is expressed in immune cells, and its dysfunction can lead to immune disorders, such as autoimmune diseases and immunodeficiency diseases. 2. **Cancer**: The receptor is involved in cancer progression, particularly in hematopoietic malignancies, where it influences cell migration and differentiation. 3. **Neurological disorders**: The receptor is expressed in the brain, and its dysfunction can lead to neurological disorders, such as multiple sclerosis and Alzheimer's disease. 4. **Infectious diseases**: The receptor is involved in the entry of viruses into host cells, particularly in the context of TGF-β signaling pathways. In conclusion, the F11 receptor is a critical component of the cell-cell adhesion complex, playing a pivotal role in maintaining the integrity of various epithelial and endothelial barriers. Its dysfunction can lead to various diseases, including immune disorders, cancer, neurological disorders, and infectious diseases. Further research on the F11 receptor is necessary to understand its mechanisms of action and to develop therapeutic strategies for the treatment of these diseases.

Genular Protein ID: 4192574240

Symbol: JAM1_HUMAN

Name: Junctional adhesion molecule A

UniProtKB Accession Codes:

Q9Y624 B7Z941

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 2 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 8 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 33 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 4 PDBsum 4 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 4 RefSeq 2 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10395639

Title: Combined treatment of TNF-alpha and IFN-gamma causes redistribution of junctional adhesion molecule in human endothelial cells.

PubMed ID: 10395639

PubMed ID: 10753840

Title: Cloning of the human platelet F11 receptor: a cell adhesion molecule member of the immunoglobulin superfamily involved in platelet aggregation.

PubMed ID: 10753840

PubMed ID: 11171323

Title: Characterization and chromosomal localization of JAM-1, a platelet receptor for a stimulatory monoclonal antibody.

PubMed ID: 11171323

DOI: 10.1242/jcs.114.3.539

PubMed ID: 11230166

Title: Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

PubMed ID: 11230166

DOI: 10.1101/gr.gr1547r

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7646439

Title: Mechanisms of platelet activation by a stimulatory antibody: cross-linking of a novel platelet receptor for monoclonal antibody F11 with the Fc gamma RII receptor.

PubMed ID: 7646439

DOI: 10.1042/bj3100155

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 12665801

Title: Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides.

PubMed ID: 12665801

DOI: 10.1038/nbt810

PubMed ID: 11489913

Title: Junctional adhesion molecule (JAM) binds to PAR-3: a possible mechanism for the recruitment of PAR-3 to tight junctions.

PubMed ID: 11489913

DOI: 10.1083/jcb.200103047

PubMed ID: 11239401

Title: Junction adhesion molecule is a receptor for reovirus.

PubMed ID: 11239401

DOI: 10.1016/s0092-8674(01)00231-8

PubMed ID: 11812992

Title: JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes.

PubMed ID: 11812992

DOI: 10.1038/ni755

PubMed ID: 12810109

Title: Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response.

PubMed ID: 12810109

DOI: 10.1016/s1471-4906(03)00117-0

PubMed ID: 15528364

Title: The functional interaction of the beta 2 integrin lymphocyte function-associated antigen-1 with junctional adhesion molecule-A is mediated by the I domain.

PubMed ID: 15528364

DOI: 10.4049/jimmunol.173.10.6259

PubMed ID: 18088087

Title: Phosphoproteome of resting human platelets.

PubMed ID: 18088087

DOI: 10.1021/pr0704130

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 25481868

Title: The tight junction protein JAM-A functions as coreceptor for rotavirus entry into MA104 cells.

PubMed ID: 25481868

DOI: 10.1016/j.virol.2014.11.016

PubMed ID: 33970782

Title: Helicobacter pylori PqqE is a new virulence factor that cleaves junctional adhesion molecule A and disrupts gastric epithelial integrity.

PubMed ID: 33970782

DOI: 10.1080/19490976.2021.1921928

PubMed ID: 35067832

Title: JAM-A interacts with alpha3beta1 integrin and tetraspanins CD151 and CD9 to regulate collective cell migration of polarized epithelial cells.

PubMed ID: 35067832

DOI: 10.1007/s00018-022-04140-5

PubMed ID: 12697893

Title: Crystal structure of human junctional adhesion molecule 1: implications for reovirus binding.

PubMed ID: 12697893

DOI: 10.1073/pnas.0937718100

Sequence Information:

  • Length: 299
  • Mass: 32583
  • Checksum: D95DE2FEA23D2851
  • Sequence:
    • MGTKAQVERK LLCLFILAIL LCSLALGSVT VHSSEPEVRI PENNPVKLSC AYSGFSSPRV 
EWKFDQGDTT RLVCYNNKIT ASYEDRVTFL PTGITFKSVT REDTGTYTCM VSEEGGNSYG 
EVKVKLIVLV PPSKPTVNIP SSATIGNRAV LTCSEQDGSP PSEYTWFKDG IVMPTNPKST 
RAFSNSSYVL NPTTGELVFD PLSASDTGEY SCEARNGYGT PMTSNAVRME AVERNVGVIV 
AAVLVTLILL GILVFGIWFA YSRGHFDRTK KGTSSKKVIY SQPSARSEGE FKQTSSFLV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.