Details for: SERPINA10
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hepatoblast (CL0005026)
Fold Change: 8.2827
Cell Significance Index: 139.3100 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 5.3652
Cell Significance Index: 188.5300 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: 3.8249
Cell Significance Index: 56.4600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 2.6917
Cell Significance Index: 58.3200 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 2.1275
Cell Significance Index: 32.0600 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 2.0573
Cell Significance Index: 126.1300 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 1.8205
Cell Significance Index: 346.4500 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.1072
Cell Significance Index: 18.6500 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.8397
Cell Significance Index: 38.0600 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: 0.6376
Cell Significance Index: 13.5800 - Cell Name: Langerhans cell (CL0000453)
Fold Change: 0.5161
Cell Significance Index: 4.9200 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.4969
Cell Significance Index: 29.8300 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.4803
Cell Significance Index: 95.3200 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.3932
Cell Significance Index: 38.9000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.3613
Cell Significance Index: 39.3000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.3129
Cell Significance Index: 282.4800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.2197
Cell Significance Index: 35.7400 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.1789
Cell Significance Index: 12.3800 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.1291
Cell Significance Index: 80.6000 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.1180
Cell Significance Index: 1.6900 - Cell Name: paneth cell (CL0000510)
Fold Change: 0.1150
Cell Significance Index: 1.1900 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.1011
Cell Significance Index: 1.3800 - Cell Name: thymocyte (CL0000893)
Fold Change: 0.1000
Cell Significance Index: 1.2600 - Cell Name: midzonal region hepatocyte (CL0019028)
Fold Change: 0.0773
Cell Significance Index: 0.4500 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0204
Cell Significance Index: 0.5100 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0181
Cell Significance Index: 12.5000 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: 0.0061
Cell Significance Index: 0.7000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0045
Cell Significance Index: 0.1300 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: 0.0036
Cell Significance Index: 2.6700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0016
Cell Significance Index: 2.4400 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0007
Cell Significance Index: 1.3600 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 0.0002
Cell Significance Index: 0.0100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0001
Cell Significance Index: 0.0800 - Cell Name: neuron associated cell (CL0000095)
Fold Change: -0.0003
Cell Significance Index: -0.0100 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0012
Cell Significance Index: -2.3300 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0017
Cell Significance Index: -0.9400 - Cell Name: intrahepatic cholangiocyte (CL0002538)
Fold Change: -0.0027
Cell Significance Index: -0.0100 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.0027
Cell Significance Index: -1.2100 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0050
Cell Significance Index: -1.7800 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0052
Cell Significance Index: -2.8500 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0055
Cell Significance Index: -1.1600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0057
Cell Significance Index: -3.6500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0069
Cell Significance Index: -1.1700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0074
Cell Significance Index: -3.3400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0079
Cell Significance Index: -0.9000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0094
Cell Significance Index: -0.3000 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0099
Cell Significance Index: -2.8500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0100
Cell Significance Index: -2.0100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0149
Cell Significance Index: -0.4200 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0158
Cell Significance Index: -0.4300 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.0183
Cell Significance Index: -0.4600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0203
Cell Significance Index: -2.9500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0206
Cell Significance Index: -3.7200 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0210
Cell Significance Index: -0.9800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0222
Cell Significance Index: -3.0500 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0236
Cell Significance Index: -0.4900 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0264
Cell Significance Index: -3.0800 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0294
Cell Significance Index: -3.6200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0303
Cell Significance Index: -3.1500 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0316
Cell Significance Index: -1.0000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.0349
Cell Significance Index: -2.2000 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0454
Cell Significance Index: -2.3600 - Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
Fold Change: -0.0461
Cell Significance Index: -0.2400 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0484
Cell Significance Index: -2.1400 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.0504
Cell Significance Index: -1.2600 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: -0.0506
Cell Significance Index: -0.5100 - Cell Name: helper T cell (CL0000912)
Fold Change: -0.0535
Cell Significance Index: -0.7600 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0549
Cell Significance Index: -2.0800 - Cell Name: differentiation-committed oligodendrocyte precursor (CL4023059)
Fold Change: -0.0572
Cell Significance Index: -0.6800 - Cell Name: plasmablast (CL0000980)
Fold Change: -0.0603
Cell Significance Index: -0.5600 - Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
Fold Change: -0.0606
Cell Significance Index: -0.6700 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: -0.0610
Cell Significance Index: -0.5800 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: -0.0618
Cell Significance Index: -0.6400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0621
Cell Significance Index: -2.9200 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0624
Cell Significance Index: -3.5000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0661
Cell Significance Index: -1.7700 - Cell Name: hepatocyte (CL0000182)
Fold Change: -0.0678
Cell Significance Index: -0.9400 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.0728
Cell Significance Index: -1.2000 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: -0.0733
Cell Significance Index: -0.6500 - Cell Name: lung macrophage (CL1001603)
Fold Change: -0.0756
Cell Significance Index: -0.8300 - Cell Name: myeloid cell (CL0000763)
Fold Change: -0.0783
Cell Significance Index: -1.0400 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: -0.0822
Cell Significance Index: -0.9200 - Cell Name: medium spiny neuron (CL1001474)
Fold Change: -0.0823
Cell Significance Index: -1.1100 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0833
Cell Significance Index: -3.6200 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0836
Cell Significance Index: -2.9300 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0869
Cell Significance Index: -2.8500 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: -0.0921
Cell Significance Index: -0.5700 - Cell Name: prostate gland microvascular endothelial cell (CL2000059)
Fold Change: -0.0955
Cell Significance Index: -0.6900 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.0958
Cell Significance Index: -1.7700 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0958
Cell Significance Index: -3.0500 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.1046
Cell Significance Index: -1.3200 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1054
Cell Significance Index: -3.0200 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1055
Cell Significance Index: -2.0600 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.1060
Cell Significance Index: -2.7000 - Cell Name: IgG plasma cell (CL0000985)
Fold Change: -0.1072
Cell Significance Index: -0.9800 - Cell Name: mature NK T cell (CL0000814)
Fold Change: -0.1105
Cell Significance Index: -1.2500 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1146
Cell Significance Index: -3.0600 - Cell Name: peg cell (CL4033014)
Fold Change: -0.1186
Cell Significance Index: -2.7400 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1198
Cell Significance Index: -3.1500 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1213
Cell Significance Index: -2.0300
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 2749391498
Symbol: ZPI_HUMAN
Name: Protein Z-dependent protease inhibitor
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10460162
Title: The protein Z-dependent protease inhibitor is a serpin.
PubMed ID: 10460162
DOI: 10.1021/bi990641a
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9689066
Title: Isolation of a protein Z-dependent plasma protease inhibitor.
PubMed ID: 9689066
PubMed ID: 11049983
Title: Characterization of the protein Z-dependent protease inhibitor.
PubMed ID: 11049983
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 22540147
Title: Characterization of the heparin-binding site of the protein z-dependent protease inhibitor.
PubMed ID: 22540147
DOI: 10.1021/bi300353c
PubMed ID: 26091039
Title: A single kinase generates the majority of the secreted phosphoproteome.
PubMed ID: 26091039
PubMed ID: 19528533
Title: Crystal structure of protein Z-dependent inhibitor complex shows how protein Z functions as a cofactor in the membrane inhibition of factor X.
PubMed ID: 19528533
PubMed ID: 20427285
Title: Basis for the specificity and activation of the serpin protein Z-dependent proteinase inhibitor (ZPI) as an inhibitor of membrane-associated factor Xa.
PubMed ID: 20427285
PubMed ID: 23375655
Title: Identification of mutations in SLC24A4, encoding a potassium-dependent sodium/calcium exchanger, as a cause of amelogenesis imperfecta.
PubMed ID: 23375655
Sequence Information:
- Length: 444
- Mass: 50707
- Checksum: 06BD47C97BBDD700
- Sequence:
MKVVPSLLLS VLLAQVWLVP GLAPSPQSPE TPAPQNQTSR VVQAPKEEEE DEQEASEEKA SEEEKAWLMA SRQQLAKETS NFGFSLLRKI SMRHDGNMVF SPFGMSLAMT GLMLGATGPT ETQIKRGLHL QALKPTKPGL LPSLFKGLRE TLSRNLELGL TQGSFAFIHK DFDVKETFFN LSKRYFDTEC VPMNFRNASQ AKRLMNHYIN KETRGKIPKL FDEINPETKL ILVDYILFKG KWLTPFDPVF TEVDTFHLDK YKTIKVPMMY GAGKFASTFD KNFRCHVLKL PYQGNATMLV VLMEKMGDHL ALEDYLTTDL VETWLRNMKT RNMEVFFPKF KLDQKYEMHE LLRQMGIRRI FSPFADLSEL SATGRNLQVS RVLQRTVIEV DERGTEAVAG ILSEITAYSM PPVIKVDRPF HFMIYEETSG MLLFLGRVVN PTLL
Genular Protein ID: 1506186197
Symbol: G3V2W1_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 11181995
PubMed ID: 12508121
Title: The DNA sequence and analysis of human chromosome 14.
PubMed ID: 12508121
DOI: 10.1038/nature01348
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
Sequence Information:
- Length: 484
- Mass: 55114
- Checksum: A635D581DA23E361
- Sequence:
MSRSTQELLG YHCRLQDKLQ EQEGSLAAEG RHSLASAADH MKVVPSLLLS VLLAQVWLVP GLAPSPQSPE TPAPQNQTSR VVQAPKEEEE DEQEASEEKA SEEEKAWLMA SRQQLAKETS NFGFSLLRKI SMRHDGNMVF SPFGMSLAMT GLMLGATGPT ETQIKRGLHL QALKPTKPGL LPSLFKGLRE TLSRNLELGL TQGSFAFIHK DFDVKETFFN LSKRYFDTEC VPMNFRNASQ AKRLMNHYIN KETRGKIPKL FDEINPETKL ILVDYILFKG KWLTPFDPVF TEVDTFHLDK YKTIKVPMMY GAGKFASTFD KNFRCHVLKL PYQGNATMLV VLMEKMGDHL ALEDYLTTDL VETWLRNMKT RNMEVFFPKF KLDQKYEMHE LLRQMGIRRI FSPFADLSEL SATGRNLQVS RVLQRTVIEV DERGTEAVAG ILSEITAYSM PPVIKVDRPF HFMIYEETSG MLLFLGRVVN PTLL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.