Details for: PDE6B

Gene ID: 5158

Symbol: PDE6B

Ensembl ID: ENSG00000133256

Description: phosphodiesterase 6B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 57.1859
    Cell Significance Index: -8.9000
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 28.0315
    Cell Significance Index: -7.1100
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 19.8643
    Cell Significance Index: -8.0700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 8.9815
    Cell Significance Index: 566.0800
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 7.3766
    Cell Significance Index: -9.1000
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 3.4824
    Cell Significance Index: 48.9100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 2.3390
    Cell Significance Index: -9.2300
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 1.1985
    Cell Significance Index: 19.7500
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 1.0945
    Cell Significance Index: 208.2900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6750
    Cell Significance Index: 66.7800
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 0.6175
    Cell Significance Index: 4.9300
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.5613
    Cell Significance Index: 11.9600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.5483
    Cell Significance Index: 79.7000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5017
    Cell Significance Index: 453.0400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.4546
    Cell Significance Index: 6.5100
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.4347
    Cell Significance Index: 19.2300
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.4333
    Cell Significance Index: 11.6100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.4328
    Cell Significance Index: 16.3900
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3506
    Cell Significance Index: 57.0300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3401
    Cell Significance Index: 36.9900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.3152
    Cell Significance Index: 3.9100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.2889
    Cell Significance Index: 6.3300
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2872
    Cell Significance Index: 57.6200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2425
    Cell Significance Index: 14.5600
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.2362
    Cell Significance Index: 14.5200
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 0.2163
    Cell Significance Index: 2.7000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.2077
    Cell Significance Index: 3.5600
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.1702
    Cell Significance Index: 5.0000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1629
    Cell Significance Index: 11.2700
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.1623
    Cell Significance Index: 58.2200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.1568
    Cell Significance Index: 8.8000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.1264
    Cell Significance Index: 8.5000
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.1188
    Cell Significance Index: 2.8500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.1005
    Cell Significance Index: 54.8800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0938
    Cell Significance Index: 10.9300
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.0936
    Cell Significance Index: 2.5100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0830
    Cell Significance Index: 0.9900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.0683
    Cell Significance Index: 8.0600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0594
    Cell Significance Index: 91.4300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0424
    Cell Significance Index: 78.2000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0416
    Cell Significance Index: 7.5000
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.0406
    Cell Significance Index: 0.4200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0382
    Cell Significance Index: 26.4400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0364
    Cell Significance Index: 68.5900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0340
    Cell Significance Index: 0.8500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0281
    Cell Significance Index: 1.4600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0249
    Cell Significance Index: 33.8900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.0153
    Cell Significance Index: 0.5300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 0.0150
    Cell Significance Index: 0.7900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 0.0119
    Cell Significance Index: 0.3400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0113
    Cell Significance Index: 1.5500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0108
    Cell Significance Index: 0.3100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0100
    Cell Significance Index: 6.3700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0047
    Cell Significance Index: 0.1300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0017
    Cell Significance Index: 0.0600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0044
    Cell Significance Index: -0.3300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0056
    Cell Significance Index: -4.2500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0058
    Cell Significance Index: -2.5800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0086
    Cell Significance Index: -1.1000
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0089
    Cell Significance Index: -6.5700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0097
    Cell Significance Index: -0.2100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0105
    Cell Significance Index: -7.7000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0110
    Cell Significance Index: -2.1800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0135
    Cell Significance Index: -1.3800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0135
    Cell Significance Index: -0.6100
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0140
    Cell Significance Index: -1.8100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0141
    Cell Significance Index: -0.3700
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0146
    Cell Significance Index: -8.2300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0150
    Cell Significance Index: -6.8200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0160
    Cell Significance Index: -9.9700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0209
    Cell Significance Index: -2.5700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0228
    Cell Significance Index: -6.5700
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0280
    Cell Significance Index: -2.1500
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: -0.0339
    Cell Significance Index: -0.2600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0403
    Cell Significance Index: -2.4700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0415
    Cell Significance Index: -1.0600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0436
    Cell Significance Index: -7.4400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0448
    Cell Significance Index: -0.9500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0455
    Cell Significance Index: -9.5900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0515
    Cell Significance Index: -1.6500
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0570
    Cell Significance Index: -6.5300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0809
    Cell Significance Index: -8.4200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0823
    Cell Significance Index: -5.3100
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0849
    Cell Significance Index: -2.7800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0860
    Cell Significance Index: -2.7400
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0904
    Cell Significance Index: -1.4500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0990
    Cell Significance Index: -4.6600
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.1019
    Cell Significance Index: -0.9700
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1087
    Cell Significance Index: -2.1500
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1090
    Cell Significance Index: -8.6400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1197
    Cell Significance Index: -5.5800
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -0.1270
    Cell Significance Index: -1.5400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1271
    Cell Significance Index: -8.9900
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1285
    Cell Significance Index: -2.5800
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1311
    Cell Significance Index: -3.2700
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.1339
    Cell Significance Index: -1.0300
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.1347
    Cell Significance Index: -2.2600
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.1415
    Cell Significance Index: -1.7700
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: -0.1469
    Cell Significance Index: -1.2100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1470
    Cell Significance Index: -5.1500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** PDE6B is a tetrameric enzyme composed of two alpha subunits and two beta subunits, which are covalently linked together. The enzyme has a unique structure, with a large catalytic domain and four binding sites for cGMP. PDE6B is a metallo-enzymatic protein, requiring a calcium ion for its catalytic activity. The enzyme is highly specific for cGMP, with a high Km value indicating a low affinity for this substrate. **Pathways and Functions** PDE6B is involved in several signaling pathways, including: 1. **Phototransduction cascade**: PDE6B is the primary enzyme responsible for terminating the phototransduction signal in photoreceptor cells. It hydrolyzes cGMP, allowing the photoreceptor to recover and reset for the next light stimulus. 2. **Ca2+ pathway**: PDE6B is activated by calcium ions, which are released from intracellular stores in response to light stimulation. The activation of PDE6B by calcium ions regulates the phototransduction cascade. 3. **Wnt signaling**: PDE6B is involved in the activation of Wnt signaling pathways, which are critical for cell proliferation and differentiation in various tissues. 4. **Circadian clock regulation**: PDE6B is expressed in the suprachiasmatic nucleus, a region of the brain that regulates the circadian clock. The enzyme is involved in the entrainment of the circadian clock by photoperiod. **Clinical Significance** Dysfunction of PDE6B has been implicated in several eye disorders, including: 1. **Retinitis pigmentosa**: A group of inherited disorders characterized by progressive vision loss and blindness. 2. **Leber congenital amaurosis**: A rare form of retinitis pigmentosa that occurs in infants and young children. 3. **Optic neuropathy**: A disorder characterized by damage to the optic nerve, leading to vision loss and blindness. Additionally, PDE6B has been implicated in the pathogenesis of other diseases, including: 1. **Cancer**: PDE6B has been shown to be overexpressed in certain types of cancer, including colorectal cancer. 2. **Neurodegenerative diseases**: PDE6B has been implicated in the pathogenesis of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. In summary, PDE6B is a critical enzyme involved in the phototransduction cascade and other signaling pathways. Its dysfunction has been implicated in various eye disorders and other diseases, highlighting the importance of this enzyme in maintaining normal cellular function.

Genular Protein ID: 648791670

Symbol: PDE6B_HUMAN

Name: N/A

UniProtKB Accession Codes:

P35913 B7Z9T9 E7ETT3 Q53XN5 Q9BWH5 Q9UD49

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEBI 10 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 2 DrugCentral 1 EC 1 EMBL 14 Ensembl 3 ExpressionAtlas 1 GO 12 Gene3D 2 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 7 KEGG 1 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 2 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 3 RefSeq 5 Rhea 2 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 1720239

Title: Genomic organization and complete sequence of the human gene encoding the beta-subunit of the cGMP phosphodiesterase and its localisation to 4p16.3.

PubMed ID: 1720239

DOI: 10.1093/nar/19.22.6263

PubMed ID: 1338685

Title: Structural studies of cDNA and the gene for the beta-subunit of cGMP phosphodiesterase from human retina.

PubMed ID: 1338685

PubMed ID: 1322354

Title: The human beta-subunit of rod photoreceptor cGMP phosphodiesterase: complete retinal cDNA sequence and evidence for expression in brain.

PubMed ID: 1322354

DOI: 10.1016/0888-7543(92)90144-h

PubMed ID: 8394243

Title: The human rod photoreceptor cGMP phosphodiesterase beta-subunit. Structural studies of its cDNA and gene.

PubMed ID: 8394243

DOI: 10.1016/0014-5793(93)81003-i

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8075643

Title: Heterozygous missense mutation in the rod cGMP phosphodiesterase beta-subunit gene in autosomal dominant stationary night blindness.

PubMed ID: 8075643

DOI: 10.1038/ng0594-64

PubMed ID: 7951329

Title:

PubMed ID: 7951329

DOI: 10.1038/ng0894-551a

PubMed ID: 8768262

Title: Organization of the gene for the beta-subunit of human photoreceptor cyclic GMP phosphodiesterase.

PubMed ID: 8768262

PubMed ID: 8394174

Title: Recessive mutations in the gene encoding the beta-subunit of rod phosphodiesterase in patients with retinitis pigmentosa.

PubMed ID: 8394174

DOI: 10.1038/ng0693-130

PubMed ID: 20940301

Title: Rod phosphodiesterase-6 PDE6A and PDE6B subunits are enzymatically equivalent.

PubMed ID: 20940301

DOI: 10.1074/jbc.m110.170068

PubMed ID: 8595886

Title: Mutations in the PDE6B gene in autosomal recessive retinitis pigmentosa.

PubMed ID: 8595886

DOI: 10.1006/geno.1995.0001

PubMed ID: 8698075

Title: Screening of the PDE6B gene in patients with autosomal dominant retinitis pigmentosa.

PubMed ID: 8698075

DOI: 10.1006/exer.1996.0019

PubMed ID: 8557257

Title: A novel mutation in exon 17 of the beta-subunit of rod phosphodiesterase in two RP sisters of a consanguineous family.

PubMed ID: 8557257

DOI: 10.1007/bf00218829

PubMed ID: 8956055

Title: Identification of a novel R552Q mutation in exon 13 of the beta-subunit of rod phosphodiesterase gene in a Spanish family with autosomal recessive retinitis pigmentosa.

PubMed ID: 8956055

DOI: 10.1002/humu.1380080403

PubMed ID: 9543643

Title: A novel homozygous Ile535Asn mutation in the rod cGMP phosphodiesterase beta-subunit gene in two brothers of a Japanese family with autosomal recessive retinitis pigmentosa.

PubMed ID: 9543643

DOI: 10.1076/ceyr.17.3.332.5214

PubMed ID: 22334370

Title: Next-generation genetic testing for retinitis pigmentosa.

PubMed ID: 22334370

DOI: 10.1002/humu.22045

Sequence Information:

  • Length: 854
  • Mass: 98336
  • Checksum: BB11A519BE88C9DF
  • Sequence:
    • MSLSEEQARS FLDQNPDFAR QYFGKKLSPE NVAAACEDGC PPDCDSLRDL CQVEESTALL 
ELVQDMQESI NMERVVFKVL RRLCTLLQAD RCSLFMYRQR NGVAELATRL FSVQPDSVLE 
DCLVPPDSEI VFPLDIGVVG HVAQTKKMVN VEDVAECPHF SSFADELTDY KTKNMLATPI 
MNGKDVVAVI MAVNKLNGPF FTSEDEDVFL KYLNFATLYL KIYHLSYLHN CETRRGQVLL 
WSANKVFEEL TDIERQFHKA FYTVRAYLNC ERYSVGLLDM TKEKEFFDVW SVLMGESQPY 
SGPRTPDGRE IVFYKVIDYV LHGKEEIKVI PTPSADHWAL ASGLPSYVAE SGFICNIMNA 
SADEMFKFQE GALDDSGWLI KNVLSMPIVN KKEEIVGVAT FYNRKDGKPF DEQDEVLMES 
LTQFLGWSVM NTDTYDKMNK LENRKDIAQD MVLYHVKCDR DEIQLILPTR ARLGKEPADC 
DEDELGEILK EELPGPTTFD IYEFHFSDLE CTELDLVKCG IQMYYELGVV RKFQIPQEVL 
VRFLFSISKG YRRITYHNWR HGFNVAQTMF TLLMTGKLKS YYTDLEAFAM VTAGLCHDID 
HRGTNNLYQM KSQNPLAKLH GSSILERHHL EFGKFLLSEE TLNIYQNLNR RQHEHVIHLM 
DIAIIATDLA LYFKKRAMFQ KIVDESKNYQ DKKSWVEYLS LETTRKEIVM AMMMTACDLS 
AITKPWEVQS KVALLVAAEF WEQGDLERTV LDQQPIPMMD RNKAAELPKL QVGFIDFVCT 
FVYKEFSRFH EEILPMFDRL QNNRKEWKAL ADEYEAKVKA LEEKEEEERV AAKKVGTEIC 
NGGPAPKSST CCIL

Genular Protein ID: 3982041041

Symbol: B4DHV7_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DHV7

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 10 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 InterPro 7 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 3 PRINTS 1 PROSITE 3 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 RuleBase 1 SAM 1 SMART 2 SMR 1 SUPFAM 2

Sequence Information:

  • Length: 575
  • Mass: 66409
  • Checksum: 61A48F882C2613A7
  • Sequence:
    • MTKEKEFFDV WSVLMGESQP YSGPRTPDGR EIVFYKVIDY ILHGKEEIKV IPTPSADHWA 
LASGLPSYVA ESGFICNIMN ASADEMFKFQ EGALDDSGWL IKNVLSMPIV NKKEEIVGVA 
TFYNRKDGKP FDEQDEVLME SLTQFLGWSV MNTDTYDKMN KLENRKDIAQ DMVLYHVKCD 
GDEIQLILPT RARLGKEPAD CDEDELGEIL KEELPGPTTF DIYEFHFSDL ECTELDLVKC 
GIQMYYELGV VRKFQIPQEV LVRFLFSISK GYRRITYHNW RHGFNVAQTM FTLLMTGKLK 
SYYTDLEAFA MVTAGLCHDI DHRGTNNLYQ MKSQNPLAKL HGSSILERHH LEFGKFLLSE 
ETLNIYQNLN RRQHEHVIHL MDIAIIATDL ALYFKKRAMF QKIVDESKNY QDKKSWVEYL 
SLETTRKEIV MAMMMTACDL SAITKPWEVQ SKVALLVAAE FWEQGDLERT VLDQQPIPMM 
DRNKAAELPK LQVGFIDFVC TFVYKEFSRF HEEILPMFDR LQNNRKEWKA LADEYEAKVK 
ALEEKEEEER VAAKKVGTEI CNGGPAPKSS TCCIL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.