Details for: PIGR

Gene ID: 5284

Symbol: PIGR

Ensembl ID: ENSG00000162896

Description: polymeric immunoglobulin receptor

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 67.4327
    Cell Significance Index: -27.4000
  • Cell Name: precursor cell (CL0011115)
    Fold Change: 64.1644
    Cell Significance Index: 486.5600
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 42.6215
    Cell Significance Index: -28.6000
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 28.4003
    Cell Significance Index: -27.1200
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 28.1414
    Cell Significance Index: -86.4400
  • Cell Name: salivary gland glandular cell (CL1001596)
    Fold Change: 24.7212
    Cell Significance Index: 137.6000
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 19.2053
    Cell Significance Index: 895.4400
  • Cell Name: endothelial tip cell (CL0000704)
    Fold Change: 18.2875
    Cell Significance Index: 78.6400
  • Cell Name: seromucus secreting cell (CL0000159)
    Fold Change: 17.4389
    Cell Significance Index: 363.7000
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 12.2552
    Cell Significance Index: -32.8300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 8.5680
    Cell Significance Index: 388.3600
  • Cell Name: tuft cell of small intestine (CL0009080)
    Fold Change: 7.5110
    Cell Significance Index: 75.7700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 7.1489
    Cell Significance Index: 205.9800
  • Cell Name: mucus secreting cell of tracheobronchial tree submucosal gland (CL4033037)
    Fold Change: 4.4178
    Cell Significance Index: 29.5000
  • Cell Name: serous secreting cell of bronchus submucosal gland (CL4033005)
    Fold Change: 4.2160
    Cell Significance Index: 42.1900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 4.1580
    Cell Significance Index: 537.1900
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 3.8527
    Cell Significance Index: 3478.6900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 3.7684
    Cell Significance Index: 94.2000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 3.5888
    Cell Significance Index: 248.1900
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 3.5338
    Cell Significance Index: 52.9500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 3.3698
    Cell Significance Index: 158.3800
  • Cell Name: respiratory goblet cell (CL0002370)
    Fold Change: 2.8938
    Cell Significance Index: 29.8500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 2.8164
    Cell Significance Index: 25.9400
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 1.8944
    Cell Significance Index: 15.6600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.5858
    Cell Significance Index: 50.7900
  • Cell Name: airway submucosal gland collecting duct epithelial cell (CL4033023)
    Fold Change: 1.4385
    Cell Significance Index: 10.1000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.3161
    Cell Significance Index: 130.2000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 1.1969
    Cell Significance Index: 130.1900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 1.0081
    Cell Significance Index: 52.3700
  • Cell Name: colonocyte (CL1000347)
    Fold Change: 0.9434
    Cell Significance Index: 5.8300
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: 0.8796
    Cell Significance Index: 6.1900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.7915
    Cell Significance Index: 599.1100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.4218
    Cell Significance Index: 230.3300
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4179
    Cell Significance Index: 25.0900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.3648
    Cell Significance Index: 12.8200
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.3644
    Cell Significance Index: 7.7600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.3489
    Cell Significance Index: 66.4000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.2397
    Cell Significance Index: 27.3600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2393
    Cell Significance Index: 38.9200
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1993
    Cell Significance Index: 35.9300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.1492
    Cell Significance Index: 17.0900
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 0.0720
    Cell Significance Index: 0.7800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0286
    Cell Significance Index: 17.8700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0240
    Cell Significance Index: 2.9600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0175
    Cell Significance Index: 2.9800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0104
    Cell Significance Index: 7.6100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0043
    Cell Significance Index: -0.2200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0058
    Cell Significance Index: -0.2400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0089
    Cell Significance Index: -0.2100
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0093
    Cell Significance Index: -6.8600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0150
    Cell Significance Index: -28.2400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0167
    Cell Significance Index: -9.3900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0225
    Cell Significance Index: -41.4700
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0271
    Cell Significance Index: -41.6900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.0288
    Cell Significance Index: -0.6300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0487
    Cell Significance Index: -30.9100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0532
    Cell Significance Index: -6.2100
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0567
    Cell Significance Index: -11.9400
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0686
    Cell Significance Index: -9.4200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0742
    Cell Significance Index: -33.6800
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0786
    Cell Significance Index: -28.1900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1111
    Cell Significance Index: -31.9700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.1231
    Cell Significance Index: -54.4200
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: -0.1260
    Cell Significance Index: -0.6000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1421
    Cell Significance Index: -28.2000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.1513
    Cell Significance Index: -30.3600
  • Cell Name: enterocyte (CL0000584)
    Fold Change: -0.1902
    Cell Significance Index: -1.1800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1918
    Cell Significance Index: -19.5900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2060
    Cell Significance Index: -15.3500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2118
    Cell Significance Index: -30.7900
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.2967
    Cell Significance Index: -3.1300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.3143
    Cell Significance Index: -6.5200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.3198
    Cell Significance Index: -37.7100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.3241
    Cell Significance Index: -19.8700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3701
    Cell Significance Index: -29.3100
  • Cell Name: goblet cell (CL0000160)
    Fold Change: -0.3842
    Cell Significance Index: -3.4800
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.4268
    Cell Significance Index: -3.5300
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4304
    Cell Significance Index: -28.9400
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.4577
    Cell Significance Index: -28.8500
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: -0.4613
    Cell Significance Index: -3.6700
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: -0.4673
    Cell Significance Index: -1.7600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.4684
    Cell Significance Index: -24.4000
  • Cell Name: stem cell (CL0000034)
    Fold Change: -0.4802
    Cell Significance Index: -3.4900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.4841
    Cell Significance Index: -7.3000
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.5023
    Cell Significance Index: -6.9500
  • Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
    Fold Change: -0.5275
    Cell Significance Index: -4.8500
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.5350
    Cell Significance Index: -4.0900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.5532
    Cell Significance Index: -35.6900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.6004
    Cell Significance Index: -16.7800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.6103
    Cell Significance Index: -22.4100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.6175
    Cell Significance Index: -34.6500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.6235
    Cell Significance Index: -16.0300
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: -0.6303
    Cell Significance Index: -3.7000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.6588
    Cell Significance Index: -34.5900
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -0.6625
    Cell Significance Index: -10.2500
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.6723
    Cell Significance Index: -6.9600
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.6919
    Cell Significance Index: -20.3800
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.6956
    Cell Significance Index: -11.7000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.7621
    Cell Significance Index: -33.7100
  • Cell Name: secretory cell (CL0000151)
    Fold Change: -0.8075
    Cell Significance Index: -5.6000

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Transmembrane Receptor:** The PIGR is a transmembrane receptor, consisting of an extracellular domain, a transmembrane domain, and an intracellular domain. 2. **Polymeric Immunoglobulin Binding:** The PIGR binds to polymeric immunoglobulins (IgA), which are secreted antibodies that play a crucial role in mucosal immunity. 3. **Transcytosis:** The PIGR facilitates the transcytosis of polymeric immunoglobulins across epithelial cells, allowing them to reach the luminal surface and interact with pathogens or toxins. 4. **Immune System Regulation:** The PIGR is involved in the regulation of immune cell activation, neutrophil degranulation, and the detection of chemical stimuli involved in sensory perception. **Pathways and Functions:** 1. **Immunoglobulin Transcytosis:** The PIGR facilitates the transcytosis of polymeric immunoglobulins across epithelial cells, enabling them to reach the luminal surface and interact with pathogens or toxins. 2. **Immune Cell Activation:** The PIGR is involved in the regulation of immune cell activation, including the activation of immune cells such as neutrophils and macrophages. 3. **Neutrophil Degranulation:** The PIGR is implicated in the regulation of neutrophil degranulation, a process involved in the elimination of pathogens and toxins. 4. **Sensory Perception:** The PIGR is involved in the detection of chemical stimuli involved in sensory perception, such as the bitter taste. 5. **Extracellular Space:** The PIGR is expressed in epithelial cells that line the extracellular space, allowing it to interact with pathogens and toxins. **Clinical Significance:** 1. **Mucosal Immunity:** The PIGR plays a crucial role in mucosal immunity, particularly in the respiratory, gastrointestinal, and urinary tracts. 2. **Infectious Diseases:** Impaired PIGR function has been implicated in various infectious diseases, including respiratory tract infections, gastrointestinal infections, and urinary tract infections. 3. **Cancer:** The PIGR is also involved in the regulation of immune cell activation and tumor immunity, making it a potential target for cancer therapy. 4. **Neurological Disorders:** The PIGR is expressed in the nervous system and has been implicated in the regulation of immune cell activation and sensory perception, making it a potential target for neurological disorders such as multiple sclerosis and Parkinson's disease. In conclusion, the polymeric immunoglobulin receptor (PIGR) is a critical component of the immune system and epithelial function, playing a key role in the transcytosis of polymeric immunoglobulins, immune cell activation, and sensory perception. Impaired PIGR function has been implicated in various diseases, making it a potential target for therapeutic intervention.

Genular Protein ID: 3860893783

Symbol: PIGR_HUMAN

Name: Polymeric immunoglobulin receptor

UniProtKB Accession Codes:

P01833 Q68D81 Q8IZY7

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CPTAC 1 CTD 1 ChEMBL 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 14 EMDB 11 Ensembl 1 EvolutionaryTrace 1 GO 13 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 16 PDBsum 16 PIR 1 PRIDE 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1682231

Title: The human transmembrane secretory component (poly-Ig receptor): molecular cloning, restriction fragment length polymorphism and chromosomal sublocalization.

PubMed ID: 1682231

DOI: 10.1007/bf00201717

PubMed ID: 1355431

Title: Molecular cloning and exon-intron mapping of the gene encoding human transmembrane secretory component (the poly-Ig receptor).

PubMed ID: 1355431

DOI: 10.1002/eji.1830220920

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 2920039

Title: Molecular cloning of the human transmembrane secretory component (poly-Ig receptor) and its mRNA expression in human tissues.

PubMed ID: 2920039

DOI: 10.1016/0006-291x(89)92790-3

PubMed ID: 6526384

Title: The primary structure of human free secretory component and the arrangement of disulfide bonds.

PubMed ID: 6526384

PubMed ID: 1859628

Title: Determination of the molecular structure of the human free secretory component.

PubMed ID: 1859628

DOI: 10.1515/bchm3.1991.372.1.119

PubMed ID: 8292260

Title: The covalent linkage of secretory component to IgA. Structure of sIgA.

PubMed ID: 8292260

DOI: 10.1515/bchm3.1993.374.7-12.1023

PubMed ID: 9237679

Title: Human free secretory component is composed of the first 585 amino acid residues of the polymeric immunoglobulin receptor.

PubMed ID: 9237679

DOI: 10.1016/s0014-5793(97)00629-7

PubMed ID: 9379029

Title: Mechanism for enhanced external transfer of dimeric IgA over pentameric IgM: studies of diffusion, binding to the human polymeric Ig receptor, and epithelial transcytosis.

PubMed ID: 9379029

PubMed ID: 10229845

Title: Fine specificity of ligand-binding domain 1 in the polymeric Ig receptor: importance of the CDR2-containing region for IgM interaction.

PubMed ID: 10229845

PubMed ID: 12150896

Title: Secretory component: a new role in secretory IgA-mediated immune exclusion in vivo.

PubMed ID: 12150896

DOI: 10.1016/s1074-7613(02)00341-2

PubMed ID: 15084671

Title: A proteomic analysis of human bile.

PubMed ID: 15084671

DOI: 10.1074/mcp.m400015-mcp200

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 16740002

Title: Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.

PubMed ID: 16740002

DOI: 10.1021/pr050492k

PubMed ID: 16543244

Title: Glycans on secretory component participate in innate protection against mucosal pathogens.

PubMed ID: 16543244

DOI: 10.1074/jbc.m512958200

PubMed ID: 18780401

Title: Identification of N-linked glycoproteins in human milk by hydrophilic interaction liquid chromatography and mass spectrometry.

PubMed ID: 18780401

DOI: 10.1002/pmic.200701057

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19139490

Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.

PubMed ID: 19139490

DOI: 10.1074/mcp.m800504-mcp200

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 25946035

Title: Human basal tear peptidome characterization by CID, HCD, and ETD followed by in silico and in vitro analyses for antimicrobial peptide identification.

PubMed ID: 25946035

DOI: 10.1021/acs.jproteome.5b00179

PubMed ID: 15530357

Title: Crystal structure of a polymeric immunoglobulin binding fragment of the human polymeric immunoglobulin receptor.

PubMed ID: 15530357

DOI: 10.1016/j.str.2004.09.006

PubMed ID: 19079336

Title: Location of secretory component on the Fc edge of dimeric IgA1 reveals insight into the role of secretory IgA1 in mucosal immunity.

PubMed ID: 19079336

DOI: 10.1038/mi.2008.68

PubMed ID: 32029686

Title: Structure of the secretory immunoglobulin A core.

PubMed ID: 32029686

DOI: 10.1126/science.aaz5807

PubMed ID: 32029689

Title: Structural insights into immunoglobulin M.

PubMed ID: 32029689

DOI: 10.1126/science.aaz5425

Sequence Information:

  • Length: 764
  • Mass: 83284
  • Checksum: 927461F4EB3B05C7
  • Sequence:
    • MLLFVLTCLL AVFPAISTKS PIFGPEEVNS VEGNSVSITC YYPPTSVNRH TRKYWCRQGA 
RGGCITLISS EGYVSSKYAG RANLTNFPEN GTFVVNIAQL SQDDSGRYKC GLGINSRGLS 
FDVSLEVSQG PGLLNDTKVY TVDLGRTVTI NCPFKTENAQ KRKSLYKQIG LYPVLVIDSS 
GYVNPNYTGR IRLDIQGTGQ LLFSVVINQL RLSDAGQYLC QAGDDSNSNK KNADLQVLKP 
EPELVYEDLR GSVTFHCALG PEVANVAKFL CRQSSGENCD VVVNTLGKRA PAFEGRILLN 
PQDKDGSFSV VITGLRKEDA GRYLCGAHSD GQLQEGSPIQ AWQLFVNEES TIPRSPTVVK 
GVAGGSVAVL CPYNRKESKS IKYWCLWEGA QNGRCPLLVD SEGWVKAQYE GRLSLLEEPG 
NGTFTVILNQ LTSRDAGFYW CLTNGDTLWR TTVEIKIIEG EPNLKVPGNV TAVLGETLKV 
PCHFPCKFSS YEKYWCKWNN TGCQALPSQD EGPSKAFVNC DENSRLVSLT LNLVTRADEG 
WYWCGVKQGH FYGETAAVYV AVEERKAAGS RDVSLAKADA APDEKVLDSG FREIENKAIQ 
DPRLFAEEKA VADTRDQADG SRASVDSGSS EEQGGSSRAL VSTLVPLGLV LAVGAVAVGV 
ARARHRKNVD RVSIRSYRTD ISMSDFENSR EFGANDNMGA SSITQETSLG GKEEFVATTE 
STTETKEPKK AKRSSKEEAE MAYKDFLLQS STVAAEAQDG PQEA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.