Details for: PRKCG

Gene ID: 5582

Symbol: PRKCG

Ensembl ID: ENSG00000126583

Description: protein kinase C gamma

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 37.0993
    Cell Significance Index: -9.4100
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 3.6714
    Cell Significance Index: 104.7700
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 3.3477
    Cell Significance Index: 205.2500
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 2.2895
    Cell Significance Index: 17.5600
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 1.4252
    Cell Significance Index: 35.5400
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 1.0430
    Cell Significance Index: 70.1300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.9377
    Cell Significance Index: 178.4500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.9327
    Cell Significance Index: 35.3200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.7354
    Cell Significance Index: 32.5300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.6584
    Cell Significance Index: 65.1400
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5403
    Cell Significance Index: 487.8900
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 0.4970
    Cell Significance Index: 6.6300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.4918
    Cell Significance Index: 34.0100
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.4793
    Cell Significance Index: 6.6500
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.4320
    Cell Significance Index: 9.4600
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.4139
    Cell Significance Index: 8.8200
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: 0.3716
    Cell Significance Index: 4.1000
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3550
    Cell Significance Index: 57.7300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3463
    Cell Significance Index: 124.2200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3199
    Cell Significance Index: 34.7900
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 0.3181
    Cell Significance Index: 4.1300
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.2754
    Cell Significance Index: 2.6200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.2384
    Cell Significance Index: 47.8200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1614
    Cell Significance Index: 9.6900
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.1403
    Cell Significance Index: 25.3000
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0946
    Cell Significance Index: 65.4300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0818
    Cell Significance Index: 9.5300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0788
    Cell Significance Index: 3.5700
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.0432
    Cell Significance Index: 0.2100
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0290
    Cell Significance Index: 1.0200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0284
    Cell Significance Index: 0.7100
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0076
    Cell Significance Index: 0.2200
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0055
    Cell Significance Index: 0.1200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0005
    Cell Significance Index: 0.0600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0017
    Cell Significance Index: -3.1900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0038
    Cell Significance Index: -7.0800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0041
    Cell Significance Index: -6.3800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0051
    Cell Significance Index: -0.1000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0055
    Cell Significance Index: -3.0300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0058
    Cell Significance Index: -7.8200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0077
    Cell Significance Index: -5.7200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0126
    Cell Significance Index: -9.5200
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0135
    Cell Significance Index: -7.5900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0145
    Cell Significance Index: -9.2200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0151
    Cell Significance Index: -2.9900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0154
    Cell Significance Index: -9.6000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0182
    Cell Significance Index: -8.2500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0223
    Cell Significance Index: -0.3200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0238
    Cell Significance Index: -6.8400
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0287
    Cell Significance Index: -1.7700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0305
    Cell Significance Index: -0.9700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0370
    Cell Significance Index: -1.1900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0424
    Cell Significance Index: -8.9300
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0458
    Cell Significance Index: -0.9500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0480
    Cell Significance Index: -8.1900
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0486
    Cell Significance Index: -0.5300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0499
    Cell Significance Index: -6.8500
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0544
    Cell Significance Index: -2.3600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0568
    Cell Significance Index: -8.2500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0578
    Cell Significance Index: -7.4100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0594
    Cell Significance Index: -2.7700
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0623
    Cell Significance Index: -1.7400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0709
    Cell Significance Index: -2.3200
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0721
    Cell Significance Index: -9.3100
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0735
    Cell Significance Index: -0.9800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0782
    Cell Significance Index: -8.9600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0826
    Cell Significance Index: -4.2900
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0846
    Cell Significance Index: -2.1100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0888
    Cell Significance Index: -4.6600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0899
    Cell Significance Index: -9.3600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0910
    Cell Significance Index: -1.5600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0911
    Cell Significance Index: -9.3100
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0941
    Cell Significance Index: -1.8900
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -0.1066
    Cell Significance Index: -1.4900
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1101
    Cell Significance Index: -8.4500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.1119
    Cell Significance Index: -3.9200
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.1138
    Cell Significance Index: -2.7300
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.1170
    Cell Significance Index: -1.3700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1276
    Cell Significance Index: -9.5100
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.1317
    Cell Significance Index: -3.1900
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.1418
    Cell Significance Index: -2.9600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1435
    Cell Significance Index: -8.0500
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1454
    Cell Significance Index: -9.3800
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.1530
    Cell Significance Index: -1.4500
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.1579
    Cell Significance Index: -1.0700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1634
    Cell Significance Index: -8.5100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1637
    Cell Significance Index: -7.7000
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.1648
    Cell Significance Index: -2.0800
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1673
    Cell Significance Index: -4.4000
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1885
    Cell Significance Index: -2.8400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1899
    Cell Significance Index: -4.0300
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.2138
    Cell Significance Index: -4.6200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2286
    Cell Significance Index: -8.3900
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.2414
    Cell Significance Index: -3.0100
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.2607
    Cell Significance Index: -9.0600
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.2659
    Cell Significance Index: -6.6400
  • Cell Name: interneuron (CL0000099)
    Fold Change: -0.2697
    Cell Significance Index: -3.1500
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.2700
    Cell Significance Index: -8.5400
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.2729
    Cell Significance Index: -7.3000
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.2790
    Cell Significance Index: -3.1700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** PRKCG is a member of the protein kinase C (PKC) family, which is a group of serine/threonine kinases that play key roles in signal transduction pathways. PRKCG is unique in that it is the only member of the PKC family that is calcium-independent, meaning that it can activate its kinase activity in the absence of calcium ions. This characteristic allows PRKCG to regulate a wide range of cellular processes, including neuronal signaling, immune responses, and cell growth. PRKCG is a large protein, consisting of 551 amino acids, with multiple domains and motifs that are involved in its kinase activity and interactions with other proteins. The protein is highly phosphorylated, with multiple phosphorylation sites that are targeted by various kinases, including PKC itself. **Pathways and Functions** PRKCG is involved in a wide range of cellular processes, including: 1. **Neurotransmission and Synaptic Plasticity**: PRKCG regulates the activity of AMPA receptors, which are a type of glutamate receptor that plays a key role in synaptic plasticity and learning. 2. **Neuronal Signaling**: PRKCG is involved in the regulation of neuronal signaling pathways, including those that regulate the activity of neurotransmitter receptors and the release of neurotransmitters. 3. **Immune Responses**: PRKCG regulates the activity of immune cells, including T cells and macrophages, and plays a key role in the regulation of immune responses to infections and inflammation. 4. **Cell Growth and Survival**: PRKCG regulates the activity of cell growth and survival pathways, including those that regulate the activity of protein kinases and phosphatases. 5. **Circadian Rhythm Regulation**: PRKCG is involved in the regulation of the circadian rhythm, a complex process that regulates the body's internal clock. **Clinical Significance** Abnormalities in PRKCG expression or function have been implicated in various diseases, including: 1. **Neurological Disorders**: PRKCG has been implicated in the pathogenesis of neurological disorders, including Alzheimer's disease, Parkinson's disease, and epilepsy. 2. **Cancer**: PRKCG has been implicated in the development and progression of various types of cancer, including breast cancer, lung cancer, and colon cancer. 3. **Immune Disorders**: PRKCG has been implicated in the pathogenesis of immune disorders, including autoimmune diseases and immunodeficiency disorders. In conclusion, PRKCG is a critical regulator of various cellular processes, including neurotransmission, immune responses, and cell growth and survival. Abnormalities in PRKCG expression or function have been implicated in various diseases, highlighting the importance of this gene in human health and disease.

Genular Protein ID: 1706307999

Symbol: KPCG_HUMAN

Name: Protein kinase C gamma type

UniProtKB Accession Codes:

P05129 B7Z8Q0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 4 CPTAC 2 CTD 1 ChEBI 27 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 5 DrugCentral 1 EC 2 EMBL 6 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 42 Gene3D 3 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 12 KEGG 1 MANE-Select 1 MIM 3 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 2 PIR 1 PIRSF 1 PRINTS 2 PRO 1 PROSITE 7 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 Reactome 6 RefSeq 2 Rhea 6 SIGNOR 1 SMART 4 SMR 1 STRING 1 SUPFAM 3 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3755548

Title: Multiple, distinct forms of bovine and human protein kinase C suggest diversity in cellular signaling pathways.

PubMed ID: 3755548

DOI: 10.1126/science.3755548

PubMed ID: 8375396

Title: Activation and substrate specificity of the human protein kinase C alpha and zeta isoenzymes.

PubMed ID: 8375396

DOI: 10.1111/j.1432-1033.1993.tb18179.x

PubMed ID: 15851033

Title: The C2 domain of PKCdelta is a phosphotyrosine binding domain.

PubMed ID: 15851033

DOI: 10.1016/j.cell.2005.02.019

PubMed ID: 16377624

Title: Protein kinase C delta regulates Ser46 phosphorylation of p53 tumor suppressor in the apoptotic response to DNA damage.

PubMed ID: 16377624

DOI: 10.1074/jbc.m512074200

PubMed ID: 12417016

Title: Protein kinase C gamma (PKC gamma): function of neuron specific isotype.

PubMed ID: 12417016

DOI: 10.1093/oxfordjournals.jbchem.a003274

PubMed ID: 17629453

Title: Protein kinase C as a stress sensor.

PubMed ID: 17629453

DOI: 10.1016/j.cellsig.2007.05.014

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20596523

Title: Development and validation of a method for profiling post-translational modification activities using protein microarrays.

PubMed ID: 20596523

DOI: 10.1371/journal.pone.0011332

PubMed ID: 36040231

Title: PKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074 and Thr1075) within the CORB GTPase domain.

PubMed ID: 36040231

DOI: 10.1042/bcj20220308

PubMed ID: 9545390

Title: Segregation of a PRKCG mutation in two RP11 families.

PubMed ID: 9545390

DOI: 10.1086/301819

PubMed ID: 10441600

Title: No mutations in the coding region of the PRKCG gene in three families with retinitis pigmentosa linked to the RP11 locus on chromosome 19q.

PubMed ID: 10441600

DOI: 10.1086/302554

PubMed ID: 12644968

Title: Missense mutations in the regulatory domain of PKC gamma: a new mechanism for dominant nonepisodic cerebellar ataxia.

PubMed ID: 12644968

DOI: 10.1086/373883

PubMed ID: 29053796

Title: Exome sequencing and network analysis identifies shared mechanisms underlying spinocerebellar ataxia.

PubMed ID: 29053796

DOI: 10.1093/brain/awx251

Sequence Information:

  • Length: 697
  • Mass: 78448
  • Checksum: 3F911B5BEF713C41
  • Sequence:
    • MAGLGPGVGD SEGGPRPLFC RKGALRQKVV HEVKSHKFTA RFFKQPTFCS HCTDFIWGIG 
KQGLQCQVCS FVVHRRCHEF VTFECPGAGK GPQTDDPRNK HKFRLHSYSS PTFCDHCGSL 
LYGLVHQGMK CSCCEMNVHR RCVRSVPSLC GVDHTERRGR LQLEIRAPTA DEIHVTVGEA 
RNLIPMDPNG LSDPYVKLKL IPDPRNLTKQ KTRTVKATLN PVWNETFVFN LKPGDVERRL 
SVEVWDWDRT SRNDFMGAMS FGVSELLKAP VDGWYKLLNQ EEGEYYNVPV ADADNCSLLQ 
KFEACNYPLE LYERVRMGPS SSPIPSPSPS PTDPKRCFFG ASPGRLHISD FSFLMVLGKG 
SFGKVMLAER RGSDELYAIK ILKKDVIVQD DDVDCTLVEK RVLALGGRGP GGRPHFLTQL 
HSTFQTPDRL YFVMEYVTGG DLMYHIQQLG KFKEPHAAFY AAEIAIGLFF LHNQGIIYRD 
LKLDNVMLDA EGHIKITDFG MCKENVFPGT TTRTFCGTPD YIAPEIIAYQ PYGKSVDWWS 
FGVLLYEMLA GQPPFDGEDE EELFQAIMEQ TVTYPKSLSR EAVAICKGFL TKHPGKRLGS 
GPDGEPTIRA HGFFRWIDWE RLERLEIPPP FRPRPCGRSG ENFDKFFTRA APALTPPDRL 
VLASIDQADF QGFTYVNPDF VHPDARSPTS PVPVPVM

Genular Protein ID: 172237555

Symbol: A0A804HIU5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A804HIU5

Database IDs:

ARBA 22 AlphaFoldDB 1 Bgee 1 CDD 4 CTD 1 ChEBI 24 DisGeNET 1 EC 2 EMBL 1 Ensembl 2 GO 9 Gene3D 3 GeneTree 1 HGNC 1 InterPro 12 NCBI Taxonomy 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 4 PRINTS 2 PROSITE 11 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 Proteomes 2 ProteomicsDB 1 RefSeq 1 Rhea 6 SMART 4 SMR 1 SUPFAM 3

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 710
  • Mass: 79838
  • Checksum: ECA8CB873B4C707D
  • Sequence:
    • MAGLGPGVGD SEGGPRPLFC RKGALRQKVV HEVKSHKFTA RFFKQPTFCS HCTDFIWGIG 
KQGLQCQVCS FVVHRRCHEF VTFECPGAGK GPQTDDPRNK HKFRLHSYSS PTFCDHCGSL 
LYGLVHQGMK CSCCEMNVHR RCVRSVPSLC GVDHTERRGR LQLEIRAPTA DEIHVTVGEA 
RNLIPMDPNG LSDPYVKLKL IPDPRNLTKQ KTRTVKATLN PVWNETFVFN LKPGDVERRL 
SVEVWDWDRT SRNDFMGAMS FGVSELLKAP VDGWYKLLNQ EEGEYYNVPV ADADNCSLLQ 
KFEACNYPLE LYERVRMGPS SSPIPSPSPS PTDPKRCFFG ASPGRLHISD FSFLMVLGKG 
SFGKVMLAER RGSDELYAIK ILKKDVIVQD DDVDCTLVEK RVLALGGRGP GGRPHFLTQL 
HSTFQTPDRL YFVMEYVTGG DLMYHIQQLG KFKEPHAAFY AAEIAIGLFF LHNQGIIYRD 
LKLDNVMLDA EGHIKITDFG MCKENVFPGT TTRTFCGTPD YIAPEIIAYQ PYGKSVDWWS 
FGVLLYEMLA GQPPFDGEDE EELFQAIMEQ TVTYPKSLSR EAVAICKGFL TKHPGKRLGS 
GPDGEPTIRA HGFFRWIDWE RLERLEIPPP FRPRPCGRSG ENFDKFFTRA APALTPPDRL 
VLASIDQADF QGFTYVNPDF VHPDARSPTS PVPVPVISCT PAFQLCPRGF

Genular Protein ID: 909654838

Symbol: B7Z3W6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z3W6

Database IDs:

ARBA 22 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 4 CTD 1 ChEBI 24 DNASU 1 DisGeNET 1 EC 2 EMBL 2 GO 10 Gene3D 3 InterPro 12 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 4 PRINTS 2 PROSITE 11 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 RefSeq 1 Rhea 6 SMART 4 SUPFAM 3

Sequence Information:

  • Length: 710
  • Mass: 79720
  • Checksum: 1F4E2E5066C9996A
  • Sequence:
    • MAGLGPGVGD SEGGPRPLFC RKGALRQKVV HEVKSHKFTA RFFKQPTFCS HCTDFIWGIG 
KQGLQCQVCS FVVHRRCHEF VTFECPGAGK GPQTDDPRNK HKFRLHSYSS PTFCDHCGSL 
LYGLVHQGMK CSCCEMNVHR RCVRSVPSLC GVDHTERRGR LQLEIRAPTA DEIHVTVGEA 
RNLIPMDPNG LSDPYVKLKL IPDPRNLTKQ KTRTVKATLN PVWNETFVFN LKPGDVERRL 
SVEVWDWDRT SRNDFMGAMS FGVSELLKAP VDGWYKLLNQ EEGEYYNVPV ADADNCSLLQ 
KFEACNYPLE LYERVRMGPS SSPIPSPSPS PTDPKRCFFG ASPGRLHISG FSFLMVLGKG 
SFGKVMLAER RGSDELYAIK ILKKDVIVQD DDVDCTLVEK RVLALGGRGP GGRPHFLTQL 
HSTFQTPDRL YFVMEYVTGG DLMYHIQQLG KFKEPHAAFY AAEIAIGLFF LHNQGIIYRD 
LKLDNVMLDA EGHIKITDFG MCKENVFPGT TTRTFCGTPD YIAPEIIAYQ PYGKSVDWWS 
FGVLLYEMLA GQPPFDGEDE EELFQAIMEQ TVTYPKSLSR EAVAICKGFL TKHPGKRLGS 
GPDGEPTIRA HGFFRWIDWE RLERLEIPPP FRPRPCGRSG ENFDKFFTRA APALTPPDRL 
VLASIDQADF QGFTYVNPDF VHPDARSPTS PVPVPVISCT PAFQLCPRGS

Genular Protein ID: 1298903492

Symbol: B2R5T1_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2R5T1

Database IDs:

ARBA 22 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 4 CTD 1 ChEBI 24 DNASU 1 DisGeNET 1 EC 2 EMBL 2 GO 10 Gene3D 3 InterPro 12 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRNR 1 PIRSF 1 PIRSR 4 PRINTS 2 PROSITE 11 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 RefSeq 1 Rhea 6 SMART 4 SUPFAM 3

Sequence Information:

  • Length: 697
  • Mass: 78457
  • Checksum: 7ECADEE7B4B4801C
  • Sequence:
    • MAGLGPGVGD SEGGPRPLFC RKGALRQKVV HEVKSHKFTA RFFKQPTFCS HCTDFIWGIG 
KQGLQCQVCS FVVHRRCHEF VTFECPGAGK GPQTDDPRNK HKFRLHSYSS PTFCDHCGSL 
LYGLVHQGMK CSCCEMNVHR RCVRSVPSLC GVDHTERRGR LQLEIRAPTA DEIHVTVGEA 
RNLIPMDPNG LSDPYVKLKL IPDPRNLTKH KTRTVKATLN PVWNETFVFN LKPGDVERRL 
SVEVWDWDRT SRNDFMGAMS FGVSELLKAP VDGWYKLLNQ EEGEYYNVPV ADADNCSLLQ 
KFEACNYPLE LYERVRMGPS SSPIPSPSPS PTDPKRCFFG ASPGRLHISD FSFLMVLGKG 
SFGKVMLAER RGSDELYAIK ILKKDVIVQD DDVDCTLVEK RVLALGGRGP GGRPHFLTQL 
HSTFQTPDRL YFVMEYVTGG DLMYHIQQLG KFKEPHAAFY AAEIAIGLFF LHNQGIIYRD 
LKLDNVMLDA EGHIKITDFG MCKENVFPGT TTRTFCGTPD YIAPEIIAYQ PYGKSVDWWS 
FGVLLYEMLA GQPPFDGEDE EELFQAIMEQ TVTYPKSLSR EAVAICKGFL TKHPGKRLGS 
GPDGEPTIRA HGFFRWIDWE RLERLEIPPP FRPRPCGRSG ENFDKFFTRA APALTPPDRL 
VLASIDQADF QGFTYVNPDF VHPDARSPTS PVPVPVM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.