Details for: RHCE
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 18.8848
Cell Significance Index: -4.7900 - Cell Name: basophilic erythroblast (CL0000549)
Fold Change: 8.5199
Cell Significance Index: 3.8800 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 0.4780
Cell Significance Index: 5.1800 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.4311
Cell Significance Index: 12.4200 - Cell Name: hepatoblast (CL0005026)
Fold Change: 0.3255
Cell Significance Index: 5.4800 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 0.2705
Cell Significance Index: 3.6900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.2398
Cell Significance Index: 4.1100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.1874
Cell Significance Index: 35.6600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 0.1712
Cell Significance Index: 7.9800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.1508
Cell Significance Index: 5.7100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.1494
Cell Significance Index: 6.6100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.1370
Cell Significance Index: 39.4100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.1324
Cell Significance Index: 26.5500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.1269
Cell Significance Index: 4.4600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.1126
Cell Significance Index: 2.4400 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.1036
Cell Significance Index: 6.2200 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.0673
Cell Significance Index: 4.2400 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0481
Cell Significance Index: 3.6900 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.0450
Cell Significance Index: 4.9000 - Cell Name: germ cell (CL0000586)
Fold Change: 0.0417
Cell Significance Index: 0.3200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0356
Cell Significance Index: 12.7600 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.0333
Cell Significance Index: 30.0900 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0299
Cell Significance Index: 5.9300 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: 0.0255
Cell Significance Index: 3.7100 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0092
Cell Significance Index: 1.6600 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0088
Cell Significance Index: 0.5900 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.0083
Cell Significance Index: 0.5800 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.0081
Cell Significance Index: 0.4200 - Cell Name: cone retinal bipolar cell (CL0000752)
Fold Change: 0.0065
Cell Significance Index: 0.0500 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0064
Cell Significance Index: 11.8000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0063
Cell Significance Index: 9.7500 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0062
Cell Significance Index: 11.6400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0034
Cell Significance Index: 4.6600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.0029
Cell Significance Index: 0.4700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0018
Cell Significance Index: 0.8100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0010
Cell Significance Index: 0.1200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.0005
Cell Significance Index: 0.3400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.0000
Cell Significance Index: 0.0000 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0011
Cell Significance Index: -0.6200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0012
Cell Significance Index: -0.2100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0023
Cell Significance Index: -1.0300 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0042
Cell Significance Index: -0.0600 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0045
Cell Significance Index: -3.3700 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0054
Cell Significance Index: -3.9600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0054
Cell Significance Index: -3.0400 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0059
Cell Significance Index: -4.4800 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0071
Cell Significance Index: -0.3100 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0080
Cell Significance Index: -4.9800 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0100
Cell Significance Index: -0.3200 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0120
Cell Significance Index: -0.3800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: -0.0122
Cell Significance Index: -1.2000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0127
Cell Significance Index: -0.7800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0167
Cell Significance Index: -2.3000 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0172
Cell Significance Index: -0.9100 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0181
Cell Significance Index: -0.8200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.0206
Cell Significance Index: -1.2600 - Cell Name: intestinal crypt stem cell of large intestine (CL0009016)
Fold Change: -0.0217
Cell Significance Index: -0.1900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0217
Cell Significance Index: -4.5700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0246
Cell Significance Index: -3.1800 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0251
Cell Significance Index: -2.9300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0252
Cell Significance Index: -0.7200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0265
Cell Significance Index: -0.7100 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.0275
Cell Significance Index: -0.3000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0305
Cell Significance Index: -3.4900 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: -0.0316
Cell Significance Index: -0.4500 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0329
Cell Significance Index: -3.3700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0389
Cell Significance Index: -4.5900 - Cell Name: retinal rod cell (CL0000604)
Fold Change: -0.0394
Cell Significance Index: -0.4700 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0405
Cell Significance Index: -0.7900 - Cell Name: primitive red blood cell (CL0002355)
Fold Change: -0.0415
Cell Significance Index: -0.4700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0427
Cell Significance Index: -4.4500 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0470
Cell Significance Index: -2.6400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0484
Cell Significance Index: -3.6100 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.0501
Cell Significance Index: -3.5400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0546
Cell Significance Index: -1.7400 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.0588
Cell Significance Index: -0.7900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0632
Cell Significance Index: -4.0800 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0634
Cell Significance Index: -2.9800 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.0643
Cell Significance Index: -1.3700 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0738
Cell Significance Index: -2.0100 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.0750
Cell Significance Index: -1.8300 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.0790
Cell Significance Index: -0.9800 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.0798
Cell Significance Index: -1.3800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0812
Cell Significance Index: -2.2700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0813
Cell Significance Index: -2.0900 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.0822
Cell Significance Index: -1.8000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0834
Cell Significance Index: -2.7300 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0888
Cell Significance Index: -1.8900 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0899
Cell Significance Index: -3.1500 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: -0.0986
Cell Significance Index: -1.2300 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0986
Cell Significance Index: -3.6200 - Cell Name: keratocyte (CL0002363)
Fold Change: -0.0990
Cell Significance Index: -1.5700 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.1000
Cell Significance Index: -2.1600 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.1023
Cell Significance Index: -1.5100 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1026
Cell Significance Index: -2.7400 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1030
Cell Significance Index: -2.5700 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: -0.1045
Cell Significance Index: -1.4500 - Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.1047
Cell Significance Index: -2.5100 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1056
Cell Significance Index: -2.1200 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.1069
Cell Significance Index: -2.5900
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1956143753
Symbol: RHCE_HUMAN
Name: Rh polypeptide 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 2123099
Title: cDNA cloning of a 30 kDa erythrocyte membrane protein associated with Rh (Rhesus)-blood-group-antigen expression.
PubMed ID: 2123099
DOI: 10.1042/bj2710821
PubMed ID: 1696722
Title: Molecular cloning and protein structure of a human blood group Rh polypeptide.
PubMed ID: 1696722
PubMed ID: 1379850
Title: Multiple Rh messenger RNA isoforms are produced by alternative splicing.
PubMed ID: 1379850
PubMed ID: 7916743
Title: Isolation of a new cDNA clone encoding an Rh polypeptide associated with the Rh blood group system.
PubMed ID: 7916743
DOI: 10.1007/bf00222717
PubMed ID: 11380456
Title: 16Cys encoded by the RHce gene is associated with altered expression of the e antigen and is frequent in the R0 haplotype.
PubMed ID: 11380456
PubMed ID: 11724987
Title: E variants found in Japanese and c antigenicity alteration without substitution in the second extracellular loop.
PubMed ID: 11724987
PubMed ID: 12393640
Title: Rare RHCE phenotypes in black individuals of Afro-Caribbean origin: identification and transfusion safety.
PubMed ID: 12393640
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8188244
Title: Organization of the gene (RHCE) encoding the human blood group RhCcEe antigens and characterization of the promoter region.
PubMed ID: 8188244
PubMed ID: 3146980
Title: Protein-sequence studies on Rh-related polypeptides suggest the presence of at least two groups of proteins which associate in the human red-cell membrane.
PubMed ID: 3146980
DOI: 10.1042/bj2561043
PubMed ID: 3135863
Title: Determination of the N-terminal sequence of human red cell Rh(D) polypeptide and demonstration that the Rh(D), (c), and (E) antigens are carried by distinct polypeptide chains.
PubMed ID: 3135863
PubMed ID: 7789951
Title: Intricate combinatorial patterns of exon splicing generate multiple Rh-related isoforms in human erythroid cells.
PubMed ID: 7789951
DOI: 10.1007/bf00209483
PubMed ID: 8117271
Title: Identification of two Rh mRNA isoforms expressed in immature erythroblasts.
PubMed ID: 8117271
PubMed ID: 1898705
Title: Regarding the size of Rh proteins.
PubMed ID: 1898705
PubMed ID: 9657769
Title: Rhnull disease: the amorph type results from a novel double mutation in RhCe gene on D-negative background.
PubMed ID: 9657769
PubMed ID: 11902138
Title: RHCE represents the ancestral RH position, while RHD is the duplicated gene.
PubMed ID: 11902138
PubMed ID: 25413218
Title: Short duplication within the RHCE gene associated with an in cis deleted RHD causing a Rhnull amorph phenotype in an immunized pregnant woman with anti-Rh29.
PubMed ID: 25413218
DOI: 10.1111/trf.12937
PubMed ID: 35835865
Title: Architecture of the human erythrocyte ankyrin-1 complex.
PubMed ID: 35835865
PubMed ID: 8220426
Title: Molecular genetic basis of the human Rhesus blood group system.
PubMed ID: 8220426
DOI: 10.1038/ng0993-62
Sequence Information:
- Length: 417
- Mass: 45451
- Checksum: 0EEB9D726DB28E6C
- Sequence:
MSSKYPRSVR RCLPLCALTL EAALILLFYF FTHYDASLED QKGLVASYQV GQDLTVMAAL GLGFLTSNFR RHSWSSVAFN LFMLALGVQW AILLDGFLSQ FPPGKVVITL FSIRLATMSA MSVLISAGAV LGKVNLAQLV VMVLVEVTAL GTLRMVISNI FNTDYHMNLR HFYVFAAYFG LTVAWCLPKP LPKGTEDNDQ RATIPSLSAM LGALFLWMFW PSVNSALLRS PIQRKNAMFN TYYALAVSVV TAISGSSLAH PQRKISMTYV HSAVLAGGVA VGTSCHLIPS PWLAMVLGLV AGLISIGGAK CLPVCCNRVL GIHHISVMHS IFSLLGLLGE ITYIVLLVLH TVWNGNGMIG FQVLLSIGEL SLAIVIALTS GLLTGLLLNL KIWKAPHVAK YFDDQVFWKF PHLAVGF
Genular Protein ID: 3460125054
Symbol: A0A220QMN8_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16181207
Title: Novel weak D types 31 and 32: adsorption-elution-supported D antigen analysis and comparison to prevalent weak D types.
PubMed ID: 16181207
PubMed ID: 28671325
Title: Serologic and molecular characterization of weak D type 29.
PubMed ID: 28671325
PubMed ID: 30248182
Title: Two distinct RHCE alleles in cis to weak D type 31 alleles in individuals from different ethnicities.
PubMed ID: 30248182
DOI: 10.1111/trf.14929
Sequence Information:
- Length: 417
- Mass: 45534
- Checksum: C66C8E6D32204964
- Sequence:
MSSKYPRSVR RCLPLWALTL EAALILLFYF FTHYDASLED QKGLVASYQV GQDLTVMAAL GLGFLTSNFR RHSWSSVAFN LFMLALGVQW AILLDGFLSQ FPPGKVVITL FSIRLATMSA MSVLISAGAV LGKVNLAQLV VMVLVEVTAL GTLRMVISNI FNTDYHMNLR HFYVFAAYFG LTVAWCLPKP LPKGTEDNDQ RATIPSLSAM LGALFLWMFW PSVNSALLRS PIQRKNAMFN TYYALAVSVV TAISGSSLAH PQRKISMTYV HSAVLAGGVA VGTSCHLIPS PWLAMVLGLV AGLISIGGAK CLPVCCNRVL GIHHISVMHS IFSLLGLLGE ITYIVLLVLH TVWNGNGMIG FQVLLSIGEL SLAIVIALTS GLLTGLLLNL KIWKAPHVAK YFDDQVFWKF PHLAVGF
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.