Details for: SLIT1

Gene ID: 6585

Symbol: SLIT1

Ensembl ID: ENSG00000187122

Description: slit guidance ligand 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 3.3814
    Cell Significance Index: 227.3700
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 2.8974
    Cell Significance Index: 38.6500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 2.8749
    Cell Significance Index: 82.0400
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 2.7749
    Cell Significance Index: 66.5500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 2.4297
    Cell Significance Index: 149.3400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.6400
    Cell Significance Index: 35.9100
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.2510
    Cell Significance Index: 9.6000
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.1977
    Cell Significance Index: 54.2900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9400
    Cell Significance Index: 337.1600
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.9398
    Cell Significance Index: 650.0300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.8684
    Cell Significance Index: 165.2600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.7935
    Cell Significance Index: 159.1800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5514
    Cell Significance Index: 54.5500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5375
    Cell Significance Index: 485.3500
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.4025
    Cell Significance Index: 3.8300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2455
    Cell Significance Index: 39.9400
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.1492
    Cell Significance Index: 3.7200
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.1358
    Cell Significance Index: 14.7800
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.1161
    Cell Significance Index: 1.4400
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1152
    Cell Significance Index: 3.3200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 0.0967
    Cell Significance Index: 3.0800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0342
    Cell Significance Index: 21.7200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.0217
    Cell Significance Index: 0.7100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.0137
    Cell Significance Index: 0.2900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0058
    Cell Significance Index: -10.9700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0064
    Cell Significance Index: -0.2800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0077
    Cell Significance Index: -0.2700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0112
    Cell Significance Index: -20.6400
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0132
    Cell Significance Index: -20.3600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0145
    Cell Significance Index: -19.7800
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0174
    Cell Significance Index: -0.1900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0232
    Cell Significance Index: -17.1700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0301
    Cell Significance Index: -22.8000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0315
    Cell Significance Index: -17.7800
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.0350
    Cell Significance Index: -2.4200
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0373
    Cell Significance Index: -16.9100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0452
    Cell Significance Index: -1.1300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0507
    Cell Significance Index: -10.0600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0524
    Cell Significance Index: -7.6100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0545
    Cell Significance Index: -3.0600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0670
    Cell Significance Index: -19.2900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0681
    Cell Significance Index: -0.9800
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0743
    Cell Significance Index: -13.3900
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: -0.0816
    Cell Significance Index: -0.9000
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.0832
    Cell Significance Index: -0.7200
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0865
    Cell Significance Index: -3.2800
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0998
    Cell Significance Index: -2.7900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1004
    Cell Significance Index: -11.7000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1005
    Cell Significance Index: -6.1600
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.1034
    Cell Significance Index: -1.5700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1065
    Cell Significance Index: -22.4400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1068
    Cell Significance Index: -2.1500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1205
    Cell Significance Index: -2.6100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1295
    Cell Significance Index: -15.9200
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1381
    Cell Significance Index: -23.5800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.1451
    Cell Significance Index: -6.4200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.1531
    Cell Significance Index: -9.1900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1593
    Cell Significance Index: -21.8700
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.1742
    Cell Significance Index: -2.0300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1852
    Cell Significance Index: -4.6200
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1879
    Cell Significance Index: -19.1900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1953
    Cell Significance Index: -22.3700
  • Cell Name: midget ganglion cell of retina (CL4023188)
    Fold Change: -0.2035
    Cell Significance Index: -2.1200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2080
    Cell Significance Index: -24.5300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2114
    Cell Significance Index: -22.0100
  • Cell Name: melanocyte of skin (CL1000458)
    Fold Change: -0.2411
    Cell Significance Index: -3.3800
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: -0.2490
    Cell Significance Index: -1.6200
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.2564
    Cell Significance Index: -2.4300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.2585
    Cell Significance Index: -19.8400
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2655
    Cell Significance Index: -9.3000
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -0.2805
    Cell Significance Index: -3.5400
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -0.3092
    Cell Significance Index: -4.0100
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3105
    Cell Significance Index: -6.1400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.3409
    Cell Significance Index: -21.9900
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.3424
    Cell Significance Index: -5.1600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.3619
    Cell Significance Index: -7.7400
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.3645
    Cell Significance Index: -2.4700
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.4011
    Cell Significance Index: -21.0600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.4260
    Cell Significance Index: -14.8100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.4267
    Cell Significance Index: -20.0600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4546
    Cell Significance Index: -14.5600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.4759
    Cell Significance Index: -22.1900
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.4784
    Cell Significance Index: -10.3400
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.5034
    Cell Significance Index: -6.7100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.5100
    Cell Significance Index: -13.4100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.5792
    Cell Significance Index: -30.0900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.5925
    Cell Significance Index: -15.2300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.5986
    Cell Significance Index: -6.8000
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.6033
    Cell Significance Index: -12.0300
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.6062
    Cell Significance Index: -7.2500
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.6137
    Cell Significance Index: -22.5300
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.6200
    Cell Significance Index: -5.2700
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.6334
    Cell Significance Index: -13.2200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.6356
    Cell Significance Index: -10.9900
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.6605
    Cell Significance Index: -13.4400
  • Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
    Fold Change: -0.6653
    Cell Significance Index: -6.8400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.6658
    Cell Significance Index: -11.4100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.6987
    Cell Significance Index: -14.8800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.7024
    Cell Significance Index: -20.6900
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.7232
    Cell Significance Index: -20.7300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Axon Guidance**: Slit1 is a key ligand in the Slit-Robo signaling pathway, which is involved in axon guidance, chemotaxis, and the regulation of axon extension. 2. **Chemorepulsion**: Slit1 exhibits chemorepulsive activity, which is essential for the precise migration of axons during embryonic development. 3. **Regulation of Synapse Assembly**: Slit1 also regulates the assembly of synapses, which is critical for neural circuit formation and maintenance. 4. **Expression in Neural Cells**: Slit1 is significantly expressed in various neural cells, including cerebral cortex neurons, thymocytes, and cardiac endothelial cells. 5. **Cellular Interactions**: Slit1 interacts with its receptor, Robo, and other molecules, such as Netrin-1, to regulate axon guidance and neural development. **Pathways and Functions** 1. **Axon Extension**: Slit1 regulates axon extension by binding to Robo, which inhibits axon growth and promotes the formation of growth cones. 2. **Chemotaxis**: Slit1 exhibits chemorepulsive activity, which guides axons towards specific targets during embryonic development. 3. **Synapse Assembly**: Slit1 regulates the assembly of synapses by modulating the expression of synaptic proteins and the formation of synaptic connections. 4. **Regulation of Neural Circuits**: Slit1 plays a critical role in the formation and maintenance of neural circuits, including the regulation of cortical dendrite branching and the guidance of retinal ganglion cell axons. 5. **Developmental Biology**: Slit1 is involved in various developmental processes, including embryonic olfactory bulb interneuron precursor migration, forebrain morphogenesis, and spinal cord development. **Clinical Significance** 1. **Neurological Disorders**: Abnormalities in Slit1 expression or function have been implicated in various neurological disorders, including autism, schizophrenia, and spinal cord injuries. 2. **Cognitive Impairment**: Slit1 dysregulation has been linked to cognitive impairment and learning disabilities. 3. **Neurodevelopmental Disorders**: Slit1 plays a critical role in the development of neural circuits, and dysregulation of this pathway has been implicated in neurodevelopmental disorders, such as autism and schizophrenia. 4. **Cancer**: Slit1 has been implicated in cancer, particularly in the regulation of cell migration and invasion. 5. **Therapeutic Targets**: The Slit1-Robo signaling pathway has been identified as a potential therapeutic target for the treatment of various neurological disorders and cancers. In conclusion, the Slit1 gene plays a crucial role in axon guidance, neural development, and the regulation of neural circuits. Abnormalities in Slit1 expression or function have been implicated in various neurological disorders, and the Slit1-Robo signaling pathway has been identified as a potential therapeutic target for the treatment of these disorders.

Genular Protein ID: 914102965

Symbol: SLIT1_HUMAN

Name: Slit homolog 1 protein

UniProtKB Accession Codes:

O75093 Q5T0V1 Q8WWZ2 Q9UIL7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 2 CTD 1 CarbonylDB 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 1 ExpressionAtlas 1 GO 17 Gene3D 3 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 16 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 8 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 Pumba 1 RNAct 1 Reactome 5 RefSeq 1 SIGNOR 1 SMART 9 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9813312

Title: Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system.

PubMed ID: 9813312

DOI: 10.1016/s0169-328x(98)00224-1

PubMed ID: 9693030

Title: Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.

PubMed ID: 9693030

DOI: 10.1006/geno.1998.5341

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12141424

Title: Conserved modularity and potential for alternate splicing in mouse and human Slit genes.

PubMed ID: 12141424

PubMed ID: 12200164

Title: Slit proteins: molecular guidance cues for cells ranging from neurons to leukocytes.

PubMed ID: 12200164

DOI: 10.1016/s0959-437x(02)00343-x

Sequence Information:

  • Length: 1534
  • Mass: 167926
  • Checksum: 47B11CE6704A3E1D
  • Sequence:
    • MALTPGWGSS AGPVRPELWL LLWAAAWRLG ASACPALCTC TGTTVDCHGT GLQAIPKNIP 
RNTERLELNG NNITRIHKND FAGLKQLRVL QLMENQIGAV ERGAFDDMKE LERLRLNRNQ 
LHMLPELLFQ NNQALSRLDL SENAIQAIPR KAFRGATDLK NLQLDKNQIS CIEEGAFRAL 
RGLEVLTLNN NNITTIPVSS FNHMPKLRTF RLHSNHLFCD CHLAWLSQWL RQRPTIGLFT 
QCSGPASLRG LNVAEVQKSE FSCSGQGEAG RVPTCTLSSG SCPAMCTCSN GIVDCRGKGL 
TAIPANLPET MTEIRLELNG IKSIPPGAFS PYRKLRRIDL SNNQIAEIAP DAFQGLRSLN 
SLVLYGNKIT DLPRGVFGGL YTLQLLLLNA NKINCIRPDA FQDLQNLSLL SLYDNKIQSL 
AKGTFTSLRA IQTLHLAQNP FICDCNLKWL ADFLRTNPIE TSGARCASPR RLANKRIGQI 
KSKKFRCSAK EQYFIPGTED YQLNSECNSD VVCPHKCRCE ANVVECSSLK LTKIPERIPQ 
STAELRLNNN EISILEATGM FKKLTHLKKI NLSNNKVSEI EDGAFEGAAS VSELHLTANQ 
LESIRSGMFR GLDGLRTLML RNNRISCIHN DSFTGLRNVR LLSLYDNQIT TVSPGAFDTL 
QSLSTLNLLA NPFNCNCQLA WLGGWLRKRK IVTGNPRCQN PDFLRQIPLQ DVAFPDFRCE 
EGQEEGGCLP RPQCPQECAC LDTVVRCSNK HLRALPKGIP KNVTELYLDG NQFTLVPGQL 
STFKYLQLVD LSNNKISSLS NSSFTNMSQL TTLILSYNAL QCIPPLAFQG LRSLRLLSLH 
GNDISTLQEG IFADVTSLSH LAIGANPLYC DCHLRWLSSW VKTGYKEPGI ARCAGPQDME 
GKLLLTTPAK KFECQGPPTL AVQAKCDLCL SSPCQNQGTC HNDPLEVYRC ACPSGYKGRD 
CEVSLDSCSS GPCENGGTCH AQEGEDAPFT CSCPTGFEGP TCGVNTDDCV DHACANGGVC 
VDGVGNYTCQ CPLQYEGKAC EQLVDLCSPD LNPCQHEAQC VGTPDGPRCE CMPGYAGDNC 
SENQDDCRDH RCQNGAQCMD EVNSYSCLCA EGYSGQLCEI PPHLPAPKSP CEGTECQNGA 
NCVDQGNRPV CQCLPGFGGP ECEKLLSVNF VDRDTYLQFT DLQNWPRANI TLQVSTAEDN 
GILLYNGDND HIAVELYQGH VRVSYDPGSY PSSAIYSAET INDGQFHTVE LVAFDQMVNL 
SIDGGSPMTM DNFGKHYTLN SEAPLYVGGM PVDVNSAAFR LWQILNGTGF HGCIRNLYIN 
NELQDFTKTQ MKPGVVPGCE PCRKLYCLHG ICQPNATPGP MCHCEAGWVG LHCDQPADGP 
CHGHKCVHGQ CVPLDALSYS CQCQDGYSGA LCNQAGALAE PCRGLQCLHG HCQASGTKGA 
HCVCDPGFSG ELCEQESECR GDPVRDFHQV QRGYAICQTT RPLSWVECRG SCPGQGCCQG 
LRLKRRKFTF ECSDGTSFAE EVEKPTKCGC ALCA

Genular Protein ID: 2572499641

Symbol: A6H8V1_HUMAN

Name: N/A

UniProtKB Accession Codes:

A6H8V1

Database IDs:

ARBA 10 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 3 InterPro 16 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 12 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 6 PharmGKB 1 RefSeq 1 SAM 1 SMART 9 SUPFAM 4

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 1534
  • Mass: 167954
  • Checksum: 3EDBF858F2C57BC2
  • Sequence:
    • MALTPGWGSS AGPVRPELWL LLWAAAWRLG ASACPALCTC TGTTVDCHGT GLQAIPKNIP 
RNTERLELNG NNITRIHKND FAGLKQLRVL QLMENQIGVV ERGAFDDMKE LERLRLNRNQ 
LHMLPELLFQ NNQALSRLDL SENAIQAIPR KAFRGATDLK NLQLDKNQIS CIEEGAFRAL 
RGLEVLTLNN NNITTIPVSS FNHMPKLRTF RLHSNHLFCD CHLAWLSQWL RQRPTIGLFT 
QCSGPASLRG LNVAEVQKSE FSCSGQGEAG RVPTCTLSSG SCPAMCTCSN GIVDCRGKGL 
TAIPANLPET MTEIRLELNG IKSIPPGAFS PYRKLRRIDL SNNQIAEIAP DAFQGLRSLN 
SLVLYGNKIT DLPRGVFGGL YTLQLLLLNA NKINCIRPDA FQDLQNLSLL SLYDNKIQSL 
AKGTFTSLRA IQTLHLAQNP FICDCNLKWL ADFLRTNPIE TSGARCASPR RLANKRIGQI 
KSKKFRCSAK EQYFIPGTED YQLNSECNSD VVCPHKCRCE ANVVECSSLK LTKIPERIPQ 
STAELRLNNN EISILEATGM FKKLTHLKKI NLSNNKVSEI EDGAFEGAAS VSELHLTANQ 
LESIRSGMFR GLDGLRTLML RNNRISCIHN DSFTGLRNVR LLSLYDNQIT TVSPGAFDTL 
QSLSTLNLLA NPFNCNCQLA WLGGWLRKRK IVTGNPRCQN PDFLRQIPLQ DVAFPDFRCE 
EGQEEGGCLP RPQCPQECAC LDTVVRCSNK HLRALPKGIP KNVTELYLDG NQFTLVPGQL 
STFKYLQLVD LSNNKISSLS NSSFTNMSQL TTLILSYNAL QCIPPLAFQG LRSLRLLSLH 
GNDISTLQEG IFADVTSLSH LAIGANPLYC DCHLRWLSSW VKTGYKEPGI ARCAGPQDME 
GKLLLTTPAK KFECQGPPTL AVQAKCDLCL SSPCQNQGTC HNDPLEVYRC ACPSGYKGRD 
CEVSLDSCSS GPCENGGTCH AQEGEDAPFT CSCPTGFEGP TCGVNTDDCV DHACANGGVC 
VDGVGNYTCQ CPLQYEGKAC EQLVDLCSPD LNPCQHEAQC VGTPDGPRCE CMPGYAGDNC 
SENQDDCRDH RCQNGAQCMD EVNSYSCLCA EGYSGQLCEI PPHLPAPKSP CEGTECQNGA 
NCVDQGNRPV CQCLPGFGGP ECEKLLSVNF VDRDTYLQFT DLQNWPRANI TLQVSTAEDN 
GILLYNGDND HIAVELYQGH VRVSYDPGSY PSSAIYSAET INDGQFHTVE LVAFDQMVNL 
SIDGGSPMTM DNFGKHYTLN SEAPLYVGGM PVDVNSAAFR LWQILNGTGF HGCIRNLYIN 
NELQDFTKTQ MKPGVVPGCE PCRKLYCLHG ICQPNATPGP MCHCEAGWVG LHCDQPADGP 
CHGHKCVHGQ CVPLDALSYS CQCQDGYSGA LCNQAGALAE PCRGLQCLHG HCQASGTKGA 
HCVCDPGFSG ELCEQESECR GDPVRDFHQV QRGYAICQTT RPLSWVECRG SCPGQGCCQG 
LRLKRRKFTF ECSDGTSFAE EVEKPTKCGC ALCA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.