Details for: SPP1

Gene ID: 6696

Symbol: SPP1

Ensembl ID: ENSG00000118785

Description: secreted phosphoprotein 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 172.2497
    Cell Significance Index: -43.6900
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 101.6391
    Cell Significance Index: -41.8700
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 88.4415
    Cell Significance Index: -35.9300
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 44.6525
    Cell Significance Index: 364.1200
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 37.6960
    Cell Significance Index: -35.9900
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 35.0053
    Cell Significance Index: -43.1600
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 10.9527
    Cell Significance Index: -43.2200
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 4.5364
    Cell Significance Index: 36.2200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 2.8489
    Cell Significance Index: 76.0700
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 2.1905
    Cell Significance Index: 8.2500
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 1.5887
    Cell Significance Index: 89.1500
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.1023
    Cell Significance Index: 67.7500
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.9672
    Cell Significance Index: 709.1400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7218
    Cell Significance Index: 143.2500
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: 0.3972
    Cell Significance Index: 2.4000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.3882
    Cell Significance Index: 211.9800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.2703
    Cell Significance Index: 30.9700
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.0381
    Cell Significance Index: 0.5900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0219
    Cell Significance Index: 13.8900
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0210
    Cell Significance Index: 0.2500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0174
    Cell Significance Index: 32.7000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0110
    Cell Significance Index: 3.9300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0109
    Cell Significance Index: 1.8600
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 0.0078
    Cell Significance Index: 0.0600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0174
    Cell Significance Index: -12.9000
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0180
    Cell Significance Index: -1.8400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0202
    Cell Significance Index: -11.4200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0328
    Cell Significance Index: -20.4600
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0328
    Cell Significance Index: -60.5100
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: -0.0366
    Cell Significance Index: -0.2800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0387
    Cell Significance Index: -59.5800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0402
    Cell Significance Index: -4.6800
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0445
    Cell Significance Index: -60.5200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0531
    Cell Significance Index: -36.7100
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0538
    Cell Significance Index: -40.7100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0777
    Cell Significance Index: -4.0800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0822
    Cell Significance Index: -6.5100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0859
    Cell Significance Index: -38.9700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1086
    Cell Significance Index: -31.2600
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.1299
    Cell Significance Index: -27.3500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.1339
    Cell Significance Index: -24.1400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.1377
    Cell Significance Index: -27.6300
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1518
    Cell Significance Index: -18.6600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1811
    Cell Significance Index: -24.8800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.1950
    Cell Significance Index: -9.0900
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: -0.2143
    Cell Significance Index: -2.3400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.2398
    Cell Significance Index: -30.9800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.2436
    Cell Significance Index: -35.4100
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2919
    Cell Significance Index: -33.3200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.3213
    Cell Significance Index: -37.8900
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.3302
    Cell Significance Index: -7.9200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.3321
    Cell Significance Index: -15.6100
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3548
    Cell Significance Index: -22.3600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.3584
    Cell Significance Index: -37.3200
  • Cell Name: embryonic fibroblast (CL2000042)
    Fold Change: -0.3679
    Cell Significance Index: -1.7600
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.4945
    Cell Significance Index: -33.2500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.5254
    Cell Significance Index: -39.1600
  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: -0.5493
    Cell Significance Index: -4.9500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.5623
    Cell Significance Index: -43.1500
  • Cell Name: extravillous trophoblast (CL0008036)
    Fold Change: -0.5729
    Cell Significance Index: -3.5600
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.5988
    Cell Significance Index: -31.1900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.6160
    Cell Significance Index: -39.7400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.6477
    Cell Significance Index: -33.6500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.7779
    Cell Significance Index: -21.7400
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.8004
    Cell Significance Index: -49.0700
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.8319
    Cell Significance Index: -8.9200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.8648
    Cell Significance Index: -22.2300
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.8898
    Cell Significance Index: -39.3600
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.9323
    Cell Significance Index: -15.6800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.9705
    Cell Significance Index: -25.9600
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -1.0316
    Cell Significance Index: -17.0000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -1.0381
    Cell Significance Index: -39.3100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -1.0867
    Cell Significance Index: -139.3100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.0891
    Cell Significance Index: -39.9800
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -1.0898
    Cell Significance Index: -32.1000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -1.0978
    Cell Significance Index: -20.2900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -1.0998
    Cell Significance Index: -45.0600
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.1171
    Cell Significance Index: -38.8200
  • Cell Name: melanocyte (CL0000148)
    Fold Change: -1.1387
    Cell Significance Index: -10.6700
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -1.1442
    Cell Significance Index: -57.8200
  • Cell Name: glandular epithelial cell (CL0000150)
    Fold Change: -1.1940
    Cell Significance Index: -9.5000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.2317
    Cell Significance Index: -43.1500
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: -1.2843
    Cell Significance Index: -13.5000
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.2980
    Cell Significance Index: -37.0400
  • Cell Name: mature T cell (CL0002419)
    Fold Change: -1.2980
    Cell Significance Index: -9.3400
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -1.3552
    Cell Significance Index: -39.8000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -1.3703
    Cell Significance Index: -39.2800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -1.3949
    Cell Significance Index: -45.6700
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -1.4276
    Cell Significance Index: -12.4800
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -1.4352
    Cell Significance Index: -45.7100
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -1.4668
    Cell Significance Index: -25.9200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -1.4718
    Cell Significance Index: -38.7000
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -1.4813
    Cell Significance Index: -36.9400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -1.5261
    Cell Significance Index: -32.6200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -1.5556
    Cell Significance Index: -49.2000
  • Cell Name: kidney collecting duct cell (CL1001225)
    Fold Change: -1.6018
    Cell Significance Index: -5.5000
  • Cell Name: kidney loop of Henle thin descending limb epithelial cell (CL1001111)
    Fold Change: -1.6176
    Cell Significance Index: -17.4700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.6548
    Cell Significance Index: -44.3400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -1.6879
    Cell Significance Index: -43.1200
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -1.7048
    Cell Significance Index: -37.3300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cellular localization:** SPP1 is primarily secreted by cells, including mature microglial cells, epithelial cells, and oligodendrocytes. 2. **Protein structure:** SPP1 is a phosphoprotein that consists of a single chain of 78 amino acids. 3. **Function:** SPP1 plays a crucial role in cell adhesion, differentiation, and signaling, and is involved in the regulation of various cellular processes, including osteoblast differentiation, extracellular matrix organization, and immune responses. **Pathways and Functions:** 1. **Androgen catabolic process:** SPP1 is involved in the regulation of androgen metabolism, which is essential for the development and maintenance of male reproductive tissues. 2. **Biomineral tissue development:** SPP1 plays a crucial role in the formation of mineralized tissues, including bone and teeth. 3. **Cell adhesion:** SPP1 is involved in cell adhesion to the extracellular matrix, which is essential for cell migration, differentiation, and survival. 4. **Cytokine activity:** SPP1 regulates cytokine activity, which is essential for the immune response and inflammation. 5. **Degradation of the extracellular matrix:** SPP1 is involved in the degradation of the extracellular matrix, which is essential for tissue remodeling and repair. 6. **Embryo implantation:** SPP1 plays a crucial role in the implantation of the embryo, which is essential for fetal development. 7. **Endoplasmic reticulum lumen:** SPP1 is involved in the regulation of the endoplasmic reticulum lumen, which is essential for protein folding and transport. 8. **Extracellular exosome:** SPP1 is involved in the formation of extracellular exosomes, which are essential for intercellular communication. **Clinical Significance:** 1. **Bone diseases:** SPP1 is involved in the regulation of bone metabolism, and its dysregulation can lead to bone diseases, including osteoporosis and bone cancer. 2. **Immune disorders:** SPP1 plays a crucial role in the regulation of the immune response, and its dysregulation can lead to immune disorders, including autoimmune diseases and cancer. 3. **Cancer:** SPP1 is involved in the regulation of cancer cell growth, migration, and invasion, and its dysregulation can lead to cancer progression. 4. **Neurological disorders:** SPP1 is involved in the regulation of neuroinflammation and neurodegeneration, and its dysregulation can lead to neurological disorders, including Alzheimer's disease and multiple sclerosis. In conclusion, SPP1 is a multifunctional protein that plays a crucial role in various biological processes, including cell adhesion, differentiation, and signaling. Its dysregulation can lead to various diseases, including bone diseases, immune disorders, cancer, and neurological disorders. Further research is needed to understand the complex functions of SPP1 and its role in human disease.

Genular Protein ID: 1297542400

Symbol: OSTP_HUMAN

Name: Bone sialoprotein 1

UniProtKB Accession Codes:

P10451 B2RDA1 Q15681 Q15682 Q15683 Q4W597 Q567T5 Q8NBK2 Q96IZ1

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CORUM 1 CPTC 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 ELM 1 EMBL 25 Ensembl 4 EvolutionaryTrace 1 ExpressionAtlas 1 GO 25 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PCDDB 1 PDB 2 PDBsum 2 PIR 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 6 RefSeq 5 SIGNOR 1 SMART 1 SMR 1 STRING 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2726470

Title: The cDNA and derived amino acid sequence for human osteopontin.

PubMed ID: 2726470

DOI: 10.1093/nar/17.8.3306

PubMed ID: 1974876

Title: cDNA cloning, mRNA distribution and heterogeneity, chromosomal location, and RFLP analysis of human osteopontin (OPN).

PubMed ID: 1974876

DOI: 10.1016/0888-7543(90)90191-v

PubMed ID: 1729712

Title: Inhibition of calcium oxalate crystal growth in vitro by uropontin: another member of the aspartic acid-rich protein superfamily.

PubMed ID: 1729712

DOI: 10.1073/pnas.89.1.426

PubMed ID: 7665163

Title: Genomic organization of the human osteopontin gene: exclusion of the locus from a causative role in the pathogenesis of dentinogenesis imperfecta type II.

PubMed ID: 7665163

DOI: 10.1006/geno.1995.1018

PubMed ID: 7945249

Title: Cloning and characterization of the human osteopontin gene and its promoter.

PubMed ID: 7945249

DOI: 10.1042/bj3030255

PubMed ID: 7837791

Title: Expression of osteopontin in human glioma. Its correlation with the malignancy.

PubMed ID: 7837791

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16303743

Title: Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.

PubMed ID: 16303743

DOI: 10.1093/dnares/12.2.117

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 1575754

Title: Molecular cloning and sequencing of cDNA encoding urinary stone protein, which is identical to osteopontin.

PubMed ID: 1575754

DOI: 10.1016/0006-291x(92)90669-c

PubMed ID: 2736258

Title: Purification of a human milk protein closely similar to tumor-secreted phosphoproteins and osteopontin.

PubMed ID: 2736258

DOI: 10.1016/0167-4838(89)90092-7

PubMed ID: 15869464

Title: Post-translationally modified residues of native human osteopontin are located in clusters: identification of 36 phosphorylation and five O-glycosylation sites and their biological implications.

PubMed ID: 15869464

DOI: 10.1042/bj20050341

PubMed ID: 16807684

Title: Phosphoproteomic analysis of the human pituitary.

PubMed ID: 16807684

DOI: 10.1007/s11102-006-8916-x

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 22582013

Title: Secreted kinase phosphorylates extracellular proteins that regulate biomineralization.

PubMed ID: 22582013

DOI: 10.1126/science.1217817

PubMed ID: 23234360

Title: LC-MS/MS characterization of O-glycosylation sites and glycan structures of human cerebrospinal fluid glycoproteins.

PubMed ID: 23234360

DOI: 10.1021/pr300963h

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 26091039

Title: A single kinase generates the majority of the secreted phosphoproteome.

PubMed ID: 26091039

DOI: 10.1016/j.cell.2015.05.028

PubMed ID: 25326458

Title: Identification of chondroitin sulfate linkage region glycopeptides reveals prohormones as a novel class of proteoglycans.

PubMed ID: 25326458

DOI: 10.1074/mcp.m114.043703

PubMed ID: 36213313

Title: Mass spectrometric analysis of chondroitin sulfate-linked peptides.

PubMed ID: 36213313

DOI: 10.1007/s42485-022-00092-3

PubMed ID: 37453717

Title: Mapping the Human Chondroitin Sulfate Glycoproteome Reveals an Unexpected Correlation Between Glycan Sulfation and Attachment Site Characteristics.

PubMed ID: 37453717

DOI: 10.1016/j.mcpro.2023.100617

Sequence Information:

  • Length: 314
  • Mass: 35423
  • Checksum: 4996429EC4752B86
  • Sequence:
    • MRIAVICFCL LGITCAIPVK QADSGSSEEK QLYNKYPDAV ATWLNPDPSQ KQNLLAPQNA 
VSSEETNDFK QETLPSKSNE SHDHMDDMDD EDDDDHVDSQ DSIDSNDSDD VDDTDDSHQS 
DESHHSDESD ELVTDFPTDL PATEVFTPVV PTVDTYDGRG DSVVYGLRSK SKKFRRPDIQ 
YPDATDEDIT SHMESEELNG AYKAIPVAQD LNAPSDWDSR GKDSYETSQL DDQSAETHSH 
KQSRLYKRKA NDESNEHSDV IDSQELSKVS REFHSHEFHS HEDMLVVDPK SKEEDKHLKF 
RISHELDSAS SEVN

Genular Protein ID: 3186265642

Symbol: B7Z351_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z351

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 4 GO 2 InterPro 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 Pfam 1 RefSeq 2 SAM 1 SMART 1

Sequence Information:

  • Length: 327
  • Mass: 37245
  • Checksum: D90C8AB78360F1B9
  • Sequence:
    • MGIVPRSLDK KAHRVQFQLN RIKAKIELPW GSLQLDCLMK TLKELYNKYP DAVATWLNPD 
PSQKQNLLAP QNAVSSEETN DFKQETLPSK SNESHDHMDD MDDEDDDDHV DSQDSIDSND 
SDDVDDTDDS HQSDESHHSD ESDELVTDFP TDLPATEVFT PVVPTVDTYD GRGDSVVYGL 
RSKSKKFRRP DIQYPDATDE DITSHMESEE LNGAYKAIPV AQDLNAPSDW DSRGKDSYET 
SQLDDQSAET HSHKQSRLYK RKANDESNEH SDVIDSQELS KVSREFHSHE FHSHEDMLVV 
DPKSKEEDKH LKFRISHELD SASSEVN

Genular Protein ID: 837686388

Symbol: Q3LGB0_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q3LGB0 D6R9C5

Database IDs:

ARBA 8 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 2 GO 4 GeneTree 1 HGNC 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 1 PeptideAtlas 1 Pfam 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 2 SMART 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 16807684

Title: Phosphoproteomic analysis of the human pituitary.

PubMed ID: 16807684

DOI: 10.1007/s11102-006-8916-x

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 273
  • Mass: 30776
  • Checksum: 60731AB3E45328A2
  • Sequence:
    • MRIAVICFCL LGITCAIPVK QADSGSSEEK QTLPSKSNES HDHMDDMDDE DDDDHVDSQD 
SIDSNDSDDV DDTDDSHQSD ESHHSDESDE LVTDFPTDLP ATEVFTPVVP TVDTYDGRGD 
SVVYGLRSKS KKFRRPDIQY PDATDEDITS HMESEELNGA YKAIPVAQDL NAPSDWDSRG 
KDSYETSQLD DQSAETHSHK QSRLYKRKAN DESNEHSDVI DSQELSKVSR EFHSHEFHSH 
EDMLVVDPKS KEEDKHLKFR ISHELDSASS EVN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.