Details for: TNXB

Gene ID: 7148

Symbol: TNXB

Ensembl ID: ENSG00000168477

Description: tenascin XB

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 81.5197
    Cell Significance Index: -12.6800
  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 36.7747
    Cell Significance Index: -14.9400
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 35.7534
    Cell Significance Index: -16.8800
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 15.6691
    Cell Significance Index: -14.9600
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 12.0280
    Cell Significance Index: -14.8300
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 4.3052
    Cell Significance Index: 29.1700
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.9977
    Cell Significance Index: -15.7800
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 3.6727
    Cell Significance Index: 71.6800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 3.2932
    Cell Significance Index: 166.4300
  • Cell Name: inflammatory cell (CL0009002)
    Fold Change: 2.5672
    Cell Significance Index: 14.7200
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 2.5592
    Cell Significance Index: 36.7500
  • Cell Name: fibroblast of the aortic adventitia (CL0002547)
    Fold Change: 2.3535
    Cell Significance Index: 23.7500
  • Cell Name: fibroblast of breast (CL4006000)
    Fold Change: 2.0450
    Cell Significance Index: 12.8600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 1.9731
    Cell Significance Index: 56.5600
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.8230
    Cell Significance Index: 26.2200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.8011
    Cell Significance Index: 110.0100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.5812
    Cell Significance Index: 18.6200
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 0.5700
    Cell Significance Index: 7.3000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.5425
    Cell Significance Index: 24.0000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.4513
    Cell Significance Index: 17.0900
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.4372
    Cell Significance Index: 9.3500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.3783
    Cell Significance Index: 75.8900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3698
    Cell Significance Index: 132.6300
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 0.3116
    Cell Significance Index: 3.5400
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.2715
    Cell Significance Index: 7.1400
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1643
    Cell Significance Index: 31.2700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.1457
    Cell Significance Index: 28.9200
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1057
    Cell Significance Index: 95.4600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.0851
    Cell Significance Index: 8.4200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0798
    Cell Significance Index: 2.3000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.0564
    Cell Significance Index: 4.3300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0549
    Cell Significance Index: 1.9300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0298
    Cell Significance Index: 4.8400
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.0194
    Cell Significance Index: 0.3000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0139
    Cell Significance Index: 26.2400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0042
    Cell Significance Index: 0.7600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0009
    Cell Significance Index: -1.3300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0030
    Cell Significance Index: -5.5700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0064
    Cell Significance Index: -2.8200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0085
    Cell Significance Index: -11.6100
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0112
    Cell Significance Index: -0.1600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0119
    Cell Significance Index: -7.5500
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.0133
    Cell Significance Index: -9.1700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0145
    Cell Significance Index: -1.6900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0195
    Cell Significance Index: -14.7800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0239
    Cell Significance Index: -17.6900
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0276
    Cell Significance Index: -15.0800
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0278
    Cell Significance Index: -12.6100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0302
    Cell Significance Index: -17.0100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0400
    Cell Significance Index: -5.8200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0416
    Cell Significance Index: -5.1200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0606
    Cell Significance Index: -17.4400
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0670
    Cell Significance Index: -8.5900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.0774
    Cell Significance Index: -8.4200
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0851
    Cell Significance Index: -1.3500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0878
    Cell Significance Index: -18.4900
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0891
    Cell Significance Index: -5.4600
  • Cell Name: connective tissue cell (CL0002320)
    Fold Change: -0.0965
    Cell Significance Index: -0.9300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.1016
    Cell Significance Index: -17.3500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.1052
    Cell Significance Index: -4.7700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1137
    Cell Significance Index: -5.9200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.1440
    Cell Significance Index: -3.6000
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1448
    Cell Significance Index: -18.7100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1460
    Cell Significance Index: -16.7300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1506
    Cell Significance Index: -15.6800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.1652
    Cell Significance Index: -16.8800
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1662
    Cell Significance Index: -7.8100
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1681
    Cell Significance Index: -11.6200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1714
    Cell Significance Index: -20.2100
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.1792
    Cell Significance Index: -4.3400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1939
    Cell Significance Index: -13.7100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.2058
    Cell Significance Index: -16.3000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.2252
    Cell Significance Index: -3.8600
  • Cell Name: alveolar adventitial fibroblast (CL4028006)
    Fold Change: -0.2287
    Cell Significance Index: -2.5400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2377
    Cell Significance Index: -13.3400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.2395
    Cell Significance Index: -14.3800
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2413
    Cell Significance Index: -17.9900
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.2445
    Cell Significance Index: -3.4300
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2720
    Cell Significance Index: -14.2800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2752
    Cell Significance Index: -9.6400
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2908
    Cell Significance Index: -18.7600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2925
    Cell Significance Index: -9.3200
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.2963
    Cell Significance Index: -7.3900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.3018
    Cell Significance Index: -14.0700
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3116
    Cell Significance Index: -5.2200
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: -0.3168
    Cell Significance Index: -2.9400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3344
    Cell Significance Index: -17.3700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.3387
    Cell Significance Index: -14.7300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.3393
    Cell Significance Index: -7.3500
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.3436
    Cell Significance Index: -8.5700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3714
    Cell Significance Index: -12.1600
  • Cell Name: microcirculation associated smooth muscle cell (CL0008035)
    Fold Change: -0.3845
    Cell Significance Index: -3.2300
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.3930
    Cell Significance Index: -12.4300
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: -0.3941
    Cell Significance Index: -0.9100
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.4295
    Cell Significance Index: -9.2800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.4380
    Cell Significance Index: -8.6600
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.4394
    Cell Significance Index: -8.9400
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.4445
    Cell Significance Index: -9.3100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.4489
    Cell Significance Index: -11.5400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.4513
    Cell Significance Index: -9.0600

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** TNXB exhibits several key characteristics that distinguish it from other extracellular matrix glycoproteins. These include: 1. **Hexabrachion-like structure**: TNXB exhibits a unique hexabrachion-like structure, consisting of six epidermal growth factor-like domains and six fibronectin type III domains. 2. **High expression in fibroblasts**: TNXB is predominantly expressed in fibroblasts, which are key cells responsible for producing and maintaining the extracellular matrix. 3. **Regulation of cell adhesion and migration**: TNXB interacts with various cell surface receptors, including integrins and laminin, to regulate cell adhesion, migration, and differentiation. 4. **Involvement in tissue repair and remodeling**: TNXB plays a critical role in tissue repair and remodeling, particularly during wound healing and fibrosis. 5. **Disease association**: TNXB has been implicated in various diseases, including cancer, fibrosis, and inflammatory disorders. **Pathways and Functions** TNXB is involved in several signaling pathways and cellular processes, including: 1. **Cell-cell adhesion**: TNXB interacts with cell surface receptors to regulate cell-cell adhesion, which is essential for tissue integrity and function. 2. **Cell-matrix adhesion**: TNXB binds to collagen and other extracellular matrix components to regulate cell-matrix adhesion, which is critical for tissue remodeling and repair. 3. **Cell signaling**: TNXB can activate various signaling pathways, including the MAPK and PI3K/Akt pathways, to regulate cell proliferation, differentiation, and survival. 4. **Extracellular matrix organization**: TNXB plays a key role in organizing and remodeling the extracellular matrix, which is essential for tissue development, repair, and maintenance. **Clinical Significance** TNXB has significant clinical relevance, particularly in the context of various diseases and disorders. Its dysregulation has been implicated in: 1. **Cancer**: TNXB expression is often upregulated in cancer cells, where it promotes tumor growth, invasion, and metastasis. 2. **Fibrosis**: TNXB is involved in the development of fibrosis, particularly in lung and liver disease, where it promotes fibroblast activation and collagen deposition. 3. **Inflammatory disorders**: TNXB has been implicated in inflammatory disorders, such as arthritis and atherosclerosis, where it promotes inflammation and tissue damage. 4. **Wound healing**: TNXB plays a critical role in wound healing, particularly in the early stages of tissue repair, where it regulates cell migration, proliferation, and differentiation. In summary, TNXB is a multifunctional glycoprotein that plays a critical role in regulating various cellular processes, including cell adhesion, migration, differentiation, and proliferation. Its dysregulation has significant clinical implications, particularly in the context of cancer, fibrosis, inflammatory disorders, and wound healing. Further research is needed to fully elucidate the mechanisms by which TNXB regulates cellular processes and to explore its therapeutic potential.

Genular Protein ID: 106546875

Symbol: TENX_HUMAN

Name: Hexabrachion-like protein

UniProtKB Accession Codes:

P22105 P78530 P78531 Q08424 Q08AM0 Q08AM1 Q59GU7 Q5SQD3 Q5ST74 Q7L8Q4 Q8N4R1 Q9NPK9 Q9UC10 Q9UC11 Q9UC12 Q9UC13 Q9UMG7

Database IDs:

AGR 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 3 CPTAC 1 CTD 1 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 21 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 30 Gene3D 3 GeneCards 1 GeneReviews 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 11 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 3 PDBsum 3 PIR 4 PRO 1 PROSITE 6 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 Proteomes 1 ProteomicsDB 3 Pumba 1 RNAct 1 Reactome 1 RefSeq 2 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8530023

Title: Sequences promoting the transcription of the human XA gene overlapping P450c21A correctly predict the presence of a novel, adrenal-specific, truncated form of tenascin-X.

PubMed ID: 8530023

DOI: 10.1006/geno.1995.1128

PubMed ID: 14656967

Title: Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.

PubMed ID: 14656967

DOI: 10.1101/gr.1736803

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7686164

Title: Tenascin-X: a novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B.

PubMed ID: 7686164

DOI: 10.1083/jcb.122.1.265

PubMed ID: 8923003

Title: Alternate promoters and alternate splicing of human tenascin-X, a gene with 5' and 3' ends buried in other genes.

PubMed ID: 8923003

DOI: 10.1093/hmg/5.11.1749

PubMed ID: 1373119

Title: Cluster of fibronectin type III repeats found in the human major histocompatibility complex class III region shows the highest homology with the repeats in an extracellular matrix protein, tenascin.

PubMed ID: 1373119

DOI: 10.1016/0888-7543(92)90438-x

PubMed ID: 17263730

Title: Identification and characterization of multiple species of tenascin-X in human serum.

PubMed ID: 17263730

DOI: 10.1111/j.1742-4658.2007.05671.x

PubMed ID: 2475872

Title: Transcript encoded on the opposite strand of the human steroid 21-hydroxylase/complement component C4 gene locus.

PubMed ID: 2475872

DOI: 10.1073/pnas.86.17.6582

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 17033827

Title: Interactions of human tenascin-X domains with dermal extracellular matrix molecules.

PubMed ID: 17033827

DOI: 10.1007/s00403-006-0706-9

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 11642233

Title: A recessive form of the Ehlers-Danlos syndrome caused by tenascin-X deficiency.

PubMed ID: 11642233

DOI: 10.1056/nejmoa002939

PubMed ID: 15733269

Title: Elastic fiber abnormalities in hypermobility type Ehlers-Danlos syndrome patients with tenascin-X mutations.

PubMed ID: 15733269

DOI: 10.1111/j.1399-0004.2005.00401.x

PubMed ID: 23768946

Title: Compound heterozygous mutations of the TNXB gene cause primary myopathy.

PubMed ID: 23768946

DOI: 10.1016/j.nmd.2013.04.009

PubMed ID: 23620400

Title: TNXB mutations can cause vesicoureteral reflux.

PubMed ID: 23620400

DOI: 10.1681/asn.2012121148

Sequence Information:

  • Length: 4244
  • Mass: 458388
  • Checksum: 45A3D29FDF133DBA
  • Sequence:
    • MMPAQYALTS SLVLLVLLST ARAGPFSSRS NVTLPAPRPP PQPGGHTVGA GVGSPSSQLY 
EHTVEGGEKQ VVFTHRINLP PSTGCGCPPG TEPPVLASEV QALRVRLEIL EELVKGLKEQ 
CTGGCCPASA QAGTGQTDVR TLCSLHGVFD LSRCTCSCEP GWGGPTCSDP TDAEIPPSSP 
PSASGSCPDD CNDQGRCVRG RCVCFPGYTG PSCGWPSCPG DCQGRGRCVQ GVCVCRAGFS 
GPDCSQRSCP RGCSQRGRCE GGRCVCDPGY TGDDCGMRSC PRGCSQRGRC ENGRCVCNPG 
YTGEDCGVRS CPRGCSQRGR CKDGRCVCDP GYTGEDCGTR SCPWDCGEGG RCVDGRCVCW 
PGYTGEDCST RTCPRDCRGR GRCEDGECIC DTGYSGDDCG VRSCPGDCNQ RGRCEDGRCV 
CWPGYTGTDC GSRACPRDCR GRGRCENGVC VCNAGYSGED CGVRSCPGDC RGRGRCESGR 
CMCWPGYTGR DCGTRACPGD CRGRGRCVDG RCVCNPGFTG EDCGSRRCPG DCRGHGLCED 
GVCVCDAGYS GEDCSTRSCP GGCRGRGQCL DGRCVCEDGY SGEDCGVRQC PNDCSQHGVC 
QDGVCICWEG YVSEDCSIRT CPSNCHGRGR CEEGRCLCDP GYTGPTCATR MCPADCRGRG 
RCVQGVCLCH VGYGGEDCGQ EEPPASACPG GCGPRELCRA GQCVCVEGFR GPDCAIQTCP 
GDCRGRGECH DGSCVCKDGY AGEDCGEEVP TIEGMRMHLL EETTVRTEWT PAPGPVDAYE 
IQFIPTTEGA SPPFTARVPS SASAYDQRGL APGQEYQVTV RALRGTSWGL PASKTITTMI 
DGPQDLRVVA VTPTTLELGW LRPQAEVDRF VVSYVSAGNQ RVRLEVPPEA DGTLLTDLMP 
GVEYVVTVTA ERGRAVSYPA SVRANTGSSP LGLLGTTDEP PPSGPSTTQG AQAPLLQQRP 
QELGELRVLG RDETGRLRVV WTAQPDTFAY FQLRMRVPEG PGAHEEVLPG DVRQALVPPP 
PPGTPYELSL HGVPPGGKPS DPIIYQGIMD KDEEKPGKSS GPPRLGELTV TDRTSDSLLL 
RWTVPEGEFD SFVIQYKDRD GQPQVVPVEG PQRSAVITSL DPGRKYKFVL YGFVGKKRHG 
PLVAEAKILP QSDPSPGTPP HLGNLWVTDP TPDSLHLSWT VPEGQFDTFM VQYRDRDGRP 
QVVPVEGPER SFVVSSLDPD HKYRFTLFGI ANKKRYGPLT ADGTTAPERK EEPPRPEFLE 
QPLLGELTVT GVTPDSLRLS WTVAQGPFDS FMVQYKDAQG QPQAVPVAGD ENEVTVPGLD 
PDRKYKMNLY GLRGRQRVGP ESVVAKTAPQ EDVDETPSPT ELGTEAPESP EEPLLGELTV 
TGSSPDSLSL FWTVPQGSFD SFTVQYKDRD GRPRAVRVGG KESEVTVGGL EPGHKYKMHL 
YGLHEGQRVG PVSAVGVTAP QQEETPPATE SPLEPRLGEL TVTDVTPNSV GLSWTVPEGQ 
FDSFIVQYKD KDGQPQVVPV AADQREVTVY NLEPERKYKM NMYGLHDGQR MGPLSVVIVT 
APLPPAPATE ASKPPLEPRL GELTVTDITP DSVGLSWTVP EGEFDSFVVQ YKDRDGQPQV 
VPVAADQREV TIPDLEPSRK YKFLLFGIQD GKRRSPVSVE AKTVARGDAS PGAPPRLGEL 
WVTDPTPDSL RLSWTVPEGQ FDSFVVQFKD KDGPQVVPVE GHERSVTVTP LDAGRKYRFL 
LYGLLGKKRH GPLTADGTTE ARSAMDDTGT KRPPKPRLGE ELQVTTVTQN SVGLSWTVPE 
GQFDSFVVQY KDRDGQPQVV PVEGSLREVS VPGLDPAHRY KLLLYGLHHG KRVGPISAVA 
ITAGREETET ETTAPTPPAP EPHLGELTVE EATSHTLHLS WMVTEGEFDS FEIQYTDRDG 
QLQMVRIGGD RNDITLSGLE SDHRYLVTLY GFSDGKHVGP VHVEALTVPE EEKPSEPPTA 
TPEPPIKPRL GELTVTDATP DSLSLSWTVP EGQFDHFLVQ YRNGDGQPKA VRVPGHEEGV 
TISGLEPDHK YKMNLYGFHG GQRMGPVSVV GVTAAEEETP SPTEPSMEAP EPAEEPLLGE 
LTVTGSSPDS LSLSWTVPQG RFDSFTVQYK DRDGRPQVVR VGGEESEVTV GGLEPGRKYK 
MHLYGLHEGR RVGPVSAVGV TAPEEESPDA PLAKLRLGQM TVRDITSDSL SLSWTVPEGQ 
FDHFLVQFKN GDGQPKAVRV PGHEDGVTIS GLEPDHKYKM NLYGFHGGQR VGPVSAVGLT 
APGKDEEMAP ASTEPPTPEP PIKPRLEELT VTDATPDSLS LSWTVPEGQF DHFLVQYKNG 
DGQPKATRVP GHEDRVTISG LEPDNKYKMN LYGFHGGQRV GPVSAIGVTA AEEETPSPTE 
PSMEAPEPPE EPLLGELTVT GSSPDSLSLS WTVPQGRFDS FTVQYKDRDG RPQVVRVGGE 
ESEVTVGGLE PGRKYKMHLY GLHEGRRVGP VSTVGVTAPQ EDVDETPSPT EPGTEAPGPP 
EEPLLGELTV TGSSPDSLSL SWTVPQGRFD SFTVQYKDRD GRPQAVRVGG QESKVTVRGL 
EPGRKYKMHL YGLHEGRRLG PVSAVGVTED EAETTQAVPT MTPEPPIKPR LGELTMTDAT 
PDSLSLSWTV PEGQFDHFLV QYRNGDGQPK AVRVPGHEDG VTISGLEPDH KYKMNLYGFH 
GGQRVGPISV IGVTAAEEET PSPTELSTEA PEPPEEPLLG ELTVTGSSPD SLSLSWTIPQ 
GHFDSFTVQY KDRDGRPQVM RVRGEESEVT VGGLEPGRKY KMHLYGLHEG RRVGPVSTVG 
VTAPEDEAET TQAVPTTTPE PPNKPRLGEL TVTDATPDSL SLSWMVPEGQ FDHFLVQYRN 
GDGQPKVVRV PGHEDGVTIS GLEPDHKYKM NLYGFHGGQR VGPISVIGVT AAEEETPAPT 
EPSTEAPEPP EEPLLGELTV TGSSPDSLSL SWTIPQGRFD SFTVQYKDRD GRPQVVRVRG 
EESEVTVGGL EPGCKYKMHL YGLHEGQRVG PVSAVGVTAP KDEAETTQAV PTMTPEPPIK 
PRLGELTVTD ATPDSLSLSW MVPEGQFDHF LVQYRNGDGQ PKAVRVPGHE DGVTISGLEP 
DHKYKMNLYG FHGGQRVGPV SAIGVTEEET PSPTEPSTEA PEAPEEPLLG ELTVTGSSPD 
SLSLSWTVPQ GRFDSFTVQY KDRDGQPQVV RVRGEESEVT VGGLEPGRKY KMHLYGLHEG 
QRVGPVSTVG ITAPLPTPLP VEPRLGELAV AAVTSDSVGL SWTVAQGPFD SFLVQYRDAQ 
GQPQAVPVSG DLRAVAVSGL DPARKYKFLL FGLQNGKRHG PVPVEARTAP DTKPSPRLGE 
LTVTDATPDS VGLSWTVPEG EFDSFVVQYK DKDGRLQVVP VAANQREVTV QGLEPSRKYR 
FLLYGLSGRK RLGPISADST TAPLEKELPP HLGELTVAEE TSSSLRLSWT VAQGPFDSFV 
VQYRDTDGQP RAVPVAADQR TVTVEDLEPG KKYKFLLYGL LGGKRLGPVS ALGMTAPEED 
TPAPELAPEA PEPPEEPRLG VLTVTDTTPD SMRLSWSVAQ GPFDSFVVQY EDTNGQPQAL 
LVDGDQSKIL ISGLEPSTPY RFLLYGLHEG KRLGPLSAEG TTGLAPAGQT SEESRPRLSQ 
LSVTDVTTSS LRLNWEAPPG AFDSFLLRFG VPSPSTLEPH PRPLLQRELM VPGTRHSAVL 
RDLRSGTLYS LTLYGLRGPH KADSIQGTAR TLSPVLESPR DLQFSEIRET SAKVNWMPPP 
SRADSFKVSY QLADGGEPQS VQVDGQARTQ KLQGLIPGAR YEVTVVSVRG FEESEPLTGF 
LTTVPDGPTQ LRALNLTEGF AVLHWKPPQN PVDTYDVQVT APGAPPLQAE TPGSAVDYPL 
HDLVLHTNYT ATVRGLRGPN LTSPASITFT TGLEAPRDLE AKEVTPRTAL LTWTEPPVRP 
AGYLLSFHTP GGQNQEILLP GGITSHQLLG LFPSTSYNAR LQAMWGQSLL PPVSTSFTTG 
GLRIPFPRDC GEEMQNGAGA SRTSTIFLNG NRERPLNVFC DMETDGGGWL VFQRRMDGQT 
DFWRDWEDYA HGFGNISGEF WLGNEALHSL TQAGDYSMRV DLRAGDEAVF AQYDSFHVDS 
AAEYYRLHLE GYHGTAGDSM SYHSGSVFSA RDRDPNSLLI SCAVSYRGAW WYRNCHYANL 
NGLYGSTVDH QGVSWYHWKG FEFSVPFTEM KLRPRNFRSP AGGG

Genular Protein ID: 1130478963

Symbol: Q6IPK3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q6IPK3

Database IDs:

ARBA 4 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Gene3D 2 InterPro 8 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 5 PeptideAtlas 1 Pfam 2 PharmGKB 1 RefSeq 1 SAM 1 SMART 2 SUPFAM 2

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 853
  • Mass: 93564
  • Checksum: 3AA3A3C25FEECC51
  • Sequence:
    • GGSRPVCLLK ELSLGLHWRD HFPEPHTSGR LPGLRQRQHV TKSFPSSLCT APLEKELPPH 
LGELTVAEET SSSLRLSWTV AQGPFDSFVV QYRDTDGQPR AVPVAADQRT VTVEDLEPGK 
KYKFLLYGLL GGKRLGPVSA LGMTAPEEDT PAPELAPEAP EPPEEPRLGV LTVTDTTPDS 
MRLSWSVAQG PFDSFVVQYE DTNGQPQALL VDGDQSKILI SGLEPSTPYR FLLYGLHEGK 
RLGPLSAEGT TGLAPAGQTS EESRPRLSQL SVTDVTTSSL RLNWEAPPGA FDSFLLRFGV 
PSPSTLEPHP RPLLQRELMV PGTRHSAVLR DLRSGTLYSL TLYGLRGPHK ADSIQGTART 
LSPVLESPRD LQFSEIRETS AKVNWMPPPS RADSFKVSYQ LADGGEPQSV QVDGQARTQK 
LQGLIPGARY EVTVVSVRGF EESEPLTGFL TTVPDGPTQL RALNLTEGFA VLHWKPPQNP 
VDTYDIQVTA PGAPPLQAET PGSAVDYPLH DLVLHTNYTA TVRGLRGPNL TSPASITFTT 
GLEAPRDLEA KEVTPRTALL TWTEPPVRPA GYLLSFHTPG GQTQEILLPG GITSHQLLGL 
FPSTSYNARL QAMWGQSLLP PVSTSFTTGG LRIPFPRDCG EEMQNGAGAS RTSTIFLNGN 
RERPLIVFCD METDGGGWLV FQRRMDGQTD FWRDWEDYAH GFGNISGEFW LGNEALHSLT 
QAGDYSMRVD LRAGDEAVFA QYDSFHVDSA AEYYRLHLEG YHGTAGDSMS YHSGSVFSAR 
DRDPNSLLIS CAVSYRGAWW YRNCHYANLN GLYGSTVDHQ GVSWYHWKGF EFSVPFTEMK 
LRPRNFRSPA GGG

Genular Protein ID: 1222520992

Symbol: O95681_HUMAN

Name: N/A

UniProtKB Accession Codes:

O95681

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 IntAct 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 7686164

Title: Tenascin-X: a novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B.

PubMed ID: 7686164

DOI: 10.1083/jcb.122.1.265

Sequence Information:

  • Length: 423
  • Mass: 45643
  • Checksum: 45C81F9330137F85
  • Sequence:
    • VRDITSDSLS LSWTVPEGQF DHFLVQFKNG DGQPKAVRVP GHEDGVTISG LEPDHKYKMN 
LYGFHGGQRV GPVSAVGLTA PGKDEEMAPA STEPPTPEPP IKPRLEELTV TDATPGSLSL 
SWTVPEGQFD HFLVQYKNGD GQPKATRVPG HEDRVTISGL EPDNKYKMNL YGFHGGQRVG 
PVSAIGVTAA EEETPSPTEP SMEAPEPPEE PLLGELTVTG SSPDSLSLSW TVPQGRFDSF 
TVQYKDRDGR PQVVRVGGEE SEVTVGGLEP GRKYKMHLYG LHEGRRVGPV STVGVTAPQE 
DVDETPSPTE PGTEAPEPPE EPLLGELTVT GSSPDSLSLS WTVPQGRFDS FTVQYKDRDG 
RPQAVRVGGQ ESKVTVRGLE PGRKYKMHLY GLHEGRRLGP VSAVGVTEDE AETTQAVPTM 
TPE

Genular Protein ID: 4220742730

Symbol: O95680_HUMAN

Name: N/A

UniProtKB Accession Codes:

O95680

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 2 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 7686164

Title: Tenascin-X: a novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B.

PubMed ID: 7686164

DOI: 10.1083/jcb.122.1.265

Sequence Information:

  • Length: 426
  • Mass: 46087
  • Checksum: 98A1CB9FFD295AE4
  • Sequence:
    • AGEDCGEEVP TIEGMRMHLL EETTVRTEWT PAPGPVDAYE IQFIPTTEGA SPPFTARVPS 
SASAYDQRGL APGQEHQVTV RALRGTSWGL PASKTVTTMI DGPQDLRVVA VTPTTLELGW 
LRPQAEVDRF VVSYVSADNQ RVRLEVPPEA DGTLLTDLMP GVEYVVTVTA ERGRAVSYPA 
SVRANTGSSP LGLLGTTDEP PPSGPSTTQG AQAPLLQQRP QELGELRVLG RDETGRLRVV 
WTAQPDTFAY FQLRMRVPEG PGAHEEVLPG DVRQALVPPP PPGTPYELSL HGVPPGGKPS 
DPIIYQGIMD KDEEKPGKSS GPPRLGELTV TDRTSDSLLL RWTVPEGEFD SFVIQYKDRD 
GQPQVVPVEG PQRSAVITSL DPGRKYKFVL YGFVGKKRHG PLVAEAKILP QSDPSPGTPP 
RLGNLW

Genular Protein ID: 346743373

Symbol: Q9Y464_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q9Y464

Database IDs:

AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 1 InterPro 4 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 2 Pfam 1 PharmGKB 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1

Citations:

PubMed ID: 7686164

Title: Tenascin-X: a novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B.

PubMed ID: 7686164

DOI: 10.1083/jcb.122.1.265

Sequence Information:

  • Length: 865
  • Mass: 94027
  • Checksum: 723C942248DE440F
  • Sequence:
    • LYGLRGRQRV GPESVVAKTA PQEDVDETPS PTELGTEAPE SPEEPLLGEL TVTGSSPDSL 
SLFWTVPQGS FDSFTVQYKD RDGRPRAVRV GGKESEVTVG GLEPGHKYKM HLYGLHEGQR 
VGPVSAVGLT APQQEETPPA TESPLEPRLG ELTVTDVTPN SVGLSWTVPE GQFDSFIVQY 
KDKDGQPQVV PVAAGQREVT VYNLEPERKY KMNMYGLHDG QRMGPLSVVI VTAPLPPAPA 
TEASKPPLEP RLGELTVTDI TPDSVGLSWT VPEGEFDSFV VQYKDRDGQP QVVPVAADQR 
EVTIPDLEPS RKYKFLLFGI QDGKRRSPVS VEAKTVARGD ASPGAPPRLG ELWVTDPTPD 
SLRLSWTVPE GQFDSFVVQF KDKDGPQVVP VEGHERSVTV TPLDAGRKYR FLLYGLLGKK 
RHGPLTADGT TEARSAMDDT GTKRPPKPRL GEELQVTTVT QNSVGLSWTV PEGQFDSFVV 
QYKDRDGQPQ VVPVEGSLRE VSVPGLDPAH RYKLLLYGLH HGKRVGPISA VAITAGWEET 
ETETTAPTPP APEPHLGELT VEEATSHTLH LSWMVTEGEF DSFEIQYTDR DGQLQMVRIG 
GDRNDITLSG LESDHRYLVT LYGFSDGKHV GPVHVEALTV PEEEKPSEPP TATPEPPIKP 
RLGELTVTDA TPDSLSLSWT VPEGQFDHFL VQYRNGDGQP KAVRGPGHEE GVTISGLEPD 
HKYKMNLYGF HGGQRMGPVS VVGVTAAEEE TPSPTEPSME APEPAEEPLL GELTVTGSSP 
DSLSLSWTVP QGRFDSFTVQ YKDRDGRPQV VRVGGEESEV TVGGLEPGRK YKMHLYGLHE 
GRRVGPVSAV GVTAPEEESP DAPLA

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.