Details for: USP9Y
Gene ID: 8287
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: USP9Y
Ensembl ID: ENSG00000114374
Description: ubiquitin specific peptidase 9 Y-linked
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 42.45rCSI 69.52%PRS 95.74
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CSI 29.32rCSI 36.47%PRS 92.68
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CSI 26.76rCSI 34.5%PRS 94.33
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CSI 25.18rCSI 29.5%PRS 99.46
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CSI 23.11rCSI 38.8%PRS 94.04
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CSI 21.87rCSI 26.12%PRS 93.82
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CSI 21.45rCSI 52.12%PRS 92.47
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CSI 20.29rCSI 35.83%PRS 93.72
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CSI 19.81rCSI 31.86%PRS 93.9
-
CSI 19.06rCSI 50.75%PRS 91.16
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CSI 16.79rCSI 27.02%PRS 94.6
-
CSI 16.71rCSI 39.97%PRS 92.93
-
CSI 14.93rCSI 29.64%PRS 96.37
-
CSI 14.57rCSI 49.9%PRS 91.61
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CSI 14.26rCSI 51.3%PRS 92.79
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CSI 13.19rCSI 41.26%PRS 94.67
-
CSI 13.14rCSI 29.03%PRS 93.7
-
CSI 13rCSI 42.72%PRS 92.11
-
CSI 12.84rCSI 40.14%PRS 94.16
-
CSI 12.59rCSI 16.73%PRS 98.29
-
CSI 12.34rCSI 17.49%PRS 97.51
-
CSI 11.82rCSI 30.56%PRS 97.32
-
CSI 11.24rCSI 42.49%PRS 93.4
-
CSI 11.05rCSI 48.56%PRS 95.58
-
CSI 10.93rCSI 24.51%PRS 93.87
-
CSI 10.34rCSI 15.14%PRS 99.07
-
CSI 9.86rCSI 7.5%PRS 99.54
-
CSI 9.02rCSI 23.49%PRS 94.28
-
CSI 8.43rCSI 15.15%PRS 95.65
-
CSI 8.39rCSI 13.39%PRS 95.04
-
CSI 8.11rCSI 6.29%PRS 98.94
-
CSI 8.08rCSI 16.23%PRS 96.09
-
CSI 7.95rCSI 18.52%PRS 97.77
-
CSI 7.94rCSI 9.62%PRS 86.1
-
CSI 7.86rCSI 31.15%PRS 94.27
-
CSI 7.74rCSI 8.94%PRS 95
-
CSI 7.64rCSI 44.98%PRS 93.7
-
CSI 7.59rCSI 5.9%PRS 99.45
-
CSI 7.5rCSI 8.22%PRS 98.62
-
CSI 7.38rCSI 17.62%PRS 98.84
-
CSI 7.35rCSI 13.76%PRS 94.64
-
CSI 7.32rCSI 63.24%PRS 95.36
-
CSI 7.21rCSI 35.83%PRS 94.9
-
CSI 7.14rCSI 16.48%PRS 94.24
-
CSI 7.05rCSI 11.21%PRS 96.22
-
CSI 6.97rCSI 10.01%PRS 94.3
-
CSI 6.93rCSI 12.21%PRS 95.86
-
CSI 6.88rCSI 8.83%PRS 96.79
-
CSI 6.83rCSI 19.41%PRS 96.27
-
CSI 6.7rCSI 6.83%PRS 99.04
-
CSI 6.7rCSI 16.37%PRS 94.89
-
CSI 6.7rCSI 45.6%PRS 93.13
-
CSI 6.67rCSI 9.44%PRS 94.11
-
CSI 6.49rCSI 5.27%PRS 98.13
-
CSI 6.48rCSI 10.67%PRS 98.34
-
CSI 6.36rCSI 8.66%PRS 95.54
-
CSI 6.35rCSI 8.16%PRS 94.79
-
CSI 6.03rCSI 5.81%PRS 97.21
-
CSI 5.97rCSI 12.27%PRS 91.63
-
CSI 5.97rCSI 9.12%PRS 97.89
-
CSI 5.72rCSI 14.51%PRS 96.27
-
CSI 5.69rCSI 11.06%PRS 97.92
-
CSI 5.68rCSI 23.14%PRS 93.8
-
CSI 5.58rCSI 4.01%PRS 99.59
-
CSI 5.57rCSI 34.82%PRS 94.99
-
CSI 5.49rCSI 17.56%PRS 97.37
-
CSI 5.48rCSI 4.33%PRS 96.38
-
CSI 5.44rCSI 13.47%PRS 98.79
-
CSI 5.28rCSI 4.92%PRS 98.75
-
CSI 5.17rCSI 16.83%PRS 96.65
-
CSI 5.11rCSI 6.99%PRS 94.74
-
CSI 5.1rCSI 6.97%PRS 96.72
-
CSI 5.08rCSI 20.48%PRS 98.3
-
CSI 4.94rCSI 15.91%PRS 95.73
-
CSI 4.9rCSI 12.78%PRS 98.84
-
CSI 4.84rCSI 12.77%PRS 99.13
-
CSI 4.73rCSI 22.68%PRS 98.33
-
CSI 4.69rCSI 12.54%PRS 96.54
-
CSI 4.68rCSI 7.26%PRS 97.99
-
CSI 4.64rCSI 27.4%PRS 92.92
-
CSI 4.62rCSI 13.38%PRS 94.37
-
CSI 4.55rCSI 6.95%PRS 98.8
-
CSI 4.54rCSI 3.36%PRS 96.69
-
CSI 4.46rCSI 4.21%PRS 97.13
-
CSI 4.35rCSI 9.93%PRS 95.47
-
CSI 4.31rCSI 61.18%PRS 93.72
-
CSI 4.24rCSI 24.42%PRS 96.82
-
CSI 3.82rCSI 8.41%PRS 97.94
-
CSI 3.81rCSI 8.68%PRS 94.33
-
CSI 3.74rCSI 16.47%PRS 92.18
-
CSI 3.71rCSI 6.42%PRS 96.23
-
CSI 3.7rCSI 12.41%PRS 91.21
-
CSI 3.68rCSI 10.14%PRS 97.53
-
CSI 3.63rCSI 4.2%PRS 95.79
-
CSI 3.61rCSI 17.26%PRS 96.56
-
CSI 3.53rCSI 5.38%PRS 96.49
-
CSI 3.44rCSI 13.1%PRS 95.03
-
CSI 3.14rCSI 16.52%PRS 92.15
-
CSI 3.14rCSI 23.61%PRS 91.64
-
CSI 3.13rCSI 4.59%PRS 95.56
-
CSI 1.1rCSI 12.9%PRS 89.2%
-
CSI 1.4rCSI 15.1%PRS 96.1%
-
CSI 1.7rCSI 4.4%PRS 98.4%
-
CSI 2.1rCSI 2.9%PRS 98.8%
-
CSI 2.2rCSI 9.6%PRS 98.0%
-
CSI 2.3rCSI 5.1%PRS 97.7%
-
CSI 2.3rCSI 9.1%PRS 91.9%
-
CSI 2.3rCSI 16.7%PRS 92.4%
-
CSI 2.4rCSI 18.3%PRS 93.2%
-
CSI 2.4rCSI 4.2%PRS 98.7%
-
CSI 2.5rCSI 61.2%PRS 91.5%
-
CSI 2.5rCSI 4.0%PRS 98.7%
-
CSI 2.6rCSI 12.0%PRS 91.8%
-
CSI 2.6rCSI 61.4%PRS 91.8%
-
CSI 2.9rCSI 3.1%PRS 98.4%
-
CSI 3.0rCSI 61.7%PRS 93.7%
-
CSI 3.1rCSI 62.1%PRS 93.5%
-
CSI 3.1rCSI 3.9%PRS 98.5%
-
CSI 3.1rCSI 5.6%PRS 95.1%
-
CSI 3.1rCSI 4.6%PRS 95.6%
-
CSI 3.1rCSI 23.6%PRS 91.6%
-
CSI 3.1rCSI 16.5%PRS 92.2%
-
CSI 3.4rCSI 13.1%PRS 95.0%
-
CSI 3.5rCSI 5.4%PRS 96.5%
-
CSI 3.6rCSI 17.3%PRS 96.6%
-
CSI 3.6rCSI 4.2%PRS 95.8%
-
CSI 3.7rCSI 10.1%PRS 97.5%
-
CSI 3.7rCSI 12.4%PRS 91.2%
-
CSI 3.7rCSI 6.4%PRS 96.2%
-
CSI 3.7rCSI 16.5%PRS 92.2%
-
CSI 3.8rCSI 8.7%PRS 94.3%
-
CSI 3.8rCSI 8.4%PRS 97.9%
-
CSI 4.2rCSI 24.4%PRS 96.8%
-
CSI 4.3rCSI 61.2%PRS 93.7%
-
CSI 4.4rCSI 9.9%PRS 95.5%
-
CSI 4.5rCSI 4.2%PRS 97.1%
-
CSI 4.5rCSI 3.4%PRS 96.7%
-
CSI 4.6rCSI 7.0%PRS 98.8%
-
CSI 4.6rCSI 13.4%PRS 94.4%
-
CSI 4.6rCSI 27.4%PRS 92.9%
-
CSI 4.7rCSI 7.3%PRS 98.0%
-
CSI 4.7rCSI 12.5%PRS 96.5%
-
CSI 4.7rCSI 22.7%PRS 98.3%
-
CSI 4.8rCSI 12.8%PRS 99.1%
-
CSI 4.9rCSI 12.8%PRS 98.8%
-
CSI 4.9rCSI 15.9%PRS 95.7%
-
CSI 5.1rCSI 20.5%PRS 98.3%
-
CSI 5.1rCSI 7.0%PRS 96.7%
-
CSI 5.1rCSI 7.0%PRS 94.7%
-
CSI 5.2rCSI 16.8%PRS 96.7%
-
CSI 5.3rCSI 4.9%PRS 98.8%
-
CSI 5.4rCSI 13.5%PRS 98.8%
-
CSI 5.5rCSI 4.3%PRS 96.4%
-
CSI 5.5rCSI 17.6%PRS 97.4%
-
CSI 5.6rCSI 34.8%PRS 95.0%
-
CSI 5.6rCSI 4.0%PRS 99.6%
-
CSI 5.7rCSI 23.1%PRS 93.8%
-
CSI 5.7rCSI 11.1%PRS 97.9%
-
CSI 5.7rCSI 14.5%PRS 96.3%
-
CSI 6.0rCSI 9.1%PRS 97.9%
-
CSI 6.0rCSI 12.3%PRS 91.6%
-
CSI 6.0rCSI 5.8%PRS 97.2%
-
CSI 6.4rCSI 8.2%PRS 94.8%
-
CSI 6.4rCSI 8.7%PRS 95.5%
-
CSI 6.5rCSI 10.7%PRS 98.3%
-
CSI 6.5rCSI 5.3%PRS 98.1%
-
CSI 6.7rCSI 9.4%PRS 94.1%
-
CSI 6.7rCSI 45.6%PRS 93.1%
-
CSI 6.7rCSI 16.4%PRS 94.9%
-
CSI 6.7rCSI 6.8%PRS 99.0%
-
CSI 6.8rCSI 19.4%PRS 96.3%
-
CSI 6.9rCSI 8.8%PRS 96.8%
-
CSI 6.9rCSI 12.2%PRS 95.9%
-
CSI 7.0rCSI 10.0%PRS 94.3%
-
CSI 7.1rCSI 11.2%PRS 96.2%
-
CSI 7.1rCSI 16.5%PRS 94.2%
-
CSI 7.2rCSI 35.8%PRS 94.9%
-
CSI 7.3rCSI 63.2%PRS 95.4%
-
CSI 7.4rCSI 13.8%PRS 94.6%
-
CSI 7.4rCSI 17.6%PRS 98.8%
-
CSI 7.5rCSI 8.2%PRS 98.6%
-
CSI 7.6rCSI 5.9%PRS 99.5%
-
CSI 7.6rCSI 45.0%PRS 93.7%
-
CSI 7.7rCSI 8.9%PRS 95.0%
-
CSI 7.9rCSI 31.2%PRS 94.3%
-
CSI 7.9rCSI 9.6%PRS 86.1%
-
CSI 8.0rCSI 18.5%PRS 97.8%
-
CSI 8.1rCSI 16.2%PRS 96.1%
-
CSI 8.1rCSI 6.3%PRS 98.9%
-
CSI 8.4rCSI 13.4%PRS 95.0%
-
CSI 8.4rCSI 15.2%PRS 95.7%
-
CSI 9.0rCSI 23.5%PRS 94.3%
-
CSI 9.9rCSI 7.5%PRS 99.5%
-
CSI 10.3rCSI 15.1%PRS 99.1%
-
CSI 10.9rCSI 24.5%PRS 93.9%
-
CSI 11.1rCSI 48.6%PRS 95.6%
-
CSI 11.2rCSI 42.5%PRS 93.4%
-
CSI 11.8rCSI 30.6%PRS 97.3%
-
CSI 12.3rCSI 17.5%PRS 97.5%
-
CSI 12.6rCSI 16.7%PRS 98.3%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 4060014753
Symbol: USP9Y_HUMAN
Name: Ubiquitin carboxyl-terminal hydrolase 9Y
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8922996
Title: The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.
PubMed ID: 8922996
PubMed ID: 9381176
Title: Functional coherence of the human Y chromosome.
PubMed ID: 9381176
PubMed ID: 9384609
Title: Characterisation of the coding sequence and fine mapping of the human DFFRY gene and comparative expression analysis and mapping to the Sxrb interval of the mouse Y chromosome of the Dffry gene.
PubMed ID: 9384609
DOI: 10.1093/hmg/7.1.97
PubMed ID: 12815422
Title: The male-specific region of the human Y chromosome is a mosaic of discrete sequence classes.
PubMed ID: 12815422
DOI: 10.1038/nature01722
PubMed ID: 10581029
Title: An azoospermic man with a de novo point mutation in the Y-chromosomal gene USP9Y.
PubMed ID: 10581029
DOI: 10.1038/70539
PubMed ID: 12895410
Title: Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.
PubMed ID: 12895410
DOI: 10.1071/rd03002
PubMed ID: 14759258
PubMed ID: 19246359
Title: Spermatogenesis in a man with complete deletion of USP9Y.
PubMed ID: 19246359
Sequence Information:
- Length: 2555
- Mass: 291077
- Checksum: 421D47D5899F4415
- Sequence:
MTAITHGSPV GGNDSQGQVL DGQSQHLFQQ NQTSSPDSSN ENSVATPPPE EQGQGDAPPQ HEDEEPAFPH TELANLDDMI NRPRWVVPVL PKGELEVLLE AAIDLSVKGL DVKSEACQRF FRDGLTISFT KILMDEAVSG WKFEIHRCII NNTHRLVELC VAKLSQDWFP LLELLAMALN PHCKFHIYNG TRPCELISSN AQLPEDELFA RSSDPRSPKG WLVDLINKFG TLNGFQILHD RFFNGSALNI QIIAALIKPF GQCYEFLSQH TLKKYFIPVI EIVPHLLENL TDEELKKEAK NEAKNDALSM IIKSLKNLAS RISGQDETIK NLEIFRLKMI LRLLQISSFN GKMNALNEIN KVISSVSYYT HRHSNPEEEE WLTAERMAEW IQQNNILSIV LQDSLHQPQY VEKLEKILRF VIKEKALTLQ DLDNIWAAQA GKHEAIVKNV HDLLAKLAWD FSPGQLDHLF DCFKASWTNA SKKQREKLLE LIRRLAEDDK DGVMAHKVLN LLWNLAQSDD VPVDIMDLAL SAHIKILDYS CSQDRDAQKI QWIDHFIEEL RTNDKWVIPA LKQIREICSL FGEASQNLSQ TQRSPHIFYR HDLINQLQQN HALVTLVAEN LATYMNSIRL YAGDHEDYDP QTVRLGSRYS HVQEVQERLN FLRFLLKDGQ LWLCAPQAKQ IWKCLAENAV YLCDREACFK WYSKLMGDEP DLDPDINKDF FESNVLQLDP SLLTENGMKC FERFFKAVNC RERKLIAKRR SYMMDDLELI GLDYLWRVVI QSSDEIANRA IDLLKEIYTN LGPRLKANQV VIHEDFIQSC FDRLKASYDT LCVFDGDKNS INCARQEAIR MVRVLTVIKE YINECDSDYH KERMILPMSR AFRGKHLSLI VRFPNQGRQV DELDIWSHTN DTIGSVRRCI VNRIKANVAH KKIELFVGGE LIDSEDDRKL IGQLNLKDKS LITAKLTQIN FNMPSSPDSS SDSSTASPGN HRNHYNDGPN LEVESCLPGV IMSVHPRYIS FLWQVADLGS NLNMPPLRDG ARVLMKLMPP DRTAVEKLRA VCLDHAKLGE GKLSPPLDSL FFGPSASQVL YLTEVVYALL MPAGVPLTDG SSDFQVHFLK SGGLPLVLSM LIRNNFLPNT DMETRRGAYL NALKIAKLLL TAIGYGHVRA VAEACQPVVD GTDPITQINQ VTHDQAVVLQ SALQSIPNPS SECVLRNESI LLAQEISNEA SRYMPDICVI RAIQKIIWAS ACGALGLVFS PNEEITKIYQ MTTNGSNKLE VEDEQVCCEA LEVMTLCFAL LPTALDALSK EKAWQTFIID LLLHCPSKTV RQLAQEQFFL MCTRCCMGHR PLLFFITLLF TILGSTAREK GKYSGDYFTL LRHLLNYAYN GNINIPNAEV LLVSEIDWLK RIRDNVKNTG ETGVEEPILE GHLGVTKELL AFQTSEKKYH FGCEKGGANL IKELIDDFIF PASKVYLQYL RSGELPAEQA IPVCSSPVTI NAGFELLVAL AIGCVRNLKQ IVDCLTEMYY MGTAITTCEA LTEWEYLPPV GPRPPKGFVG LKNAGATCYM NSVIQQLYMI PSIRNSILAI EGTGSDLHDD MFGDEKQDSE SNVDPRDDVF GYPHQFEDKP ALSKTEDRKE YNIGVLRHLQ VIFGHLAASQ LQYYVPRGFW KQFRLWGEPV NLREQHDALE FFNSLVDSLD EALKALGHPA ILSKVLGGSF ADQKICQGCP HRYECEESFT TLNVDIRNHQ NLLDSLEQYI KGDLLEGANA YHCEKCDKKV DTVKRLLIKK LPRVLAIQLK RFDYDWEREC AIKFNDYFEF PRELDMGPYT VAGVANLERD NVNSENELIE QKEQSDNETA GGTKYRLVGV LVHSGQASGG HYYSYIIQRN GKDDQTDHWY KFDDGDVTEC KMDDDEEMKN QCFGGEYMGE VFDHMMKRMS YRRQKRWWNA YILFYEQMDM IDEDDEMIRY ISELTIARPH QIIMSPAIER SVRKQNVKFM HNRLQYSLEY FQFVKKLLTC NGVYLNPAPG QDYLLPEAEE ITMISIQLAA RFLFTTGFHT KKIVRGPASD WYDALCVLLR HSKNVRFWFT HNVLFNVSNR FSEYLLECPS AEVRGAFAKL IVFIAHFSLQ DGSCPSPFAS PGPSSQACDN LSLSDHLLRA TLNLLRREVS EHGHHLQQYF NLFVMYANLG VAEKTQLLKL NVPATFMLVS LDEGPGPPIK YQYAELGKLY SVVSQLIRCC NVSSTMQSSI NGNPPLPNPF GDLNLSQPIM PIQQNVLDIL FVRTSYVKKI IEDCSNSEDT IKLLRFCSWE NPQFSSTVLS ELLWQVAYSY TYELRPYLDL LFQILLIEDS WQTHRIHNAL KGIPDDRDGL FDTIQRSKNH YQKRAYQCIK CMVALFSSCP VAYQILQGNG DLKRKWTWAV EWLGDELERR PYTGNPQYSY NNWSPPVQSN ETANGYFLER SHSARMTLAK ACELCPEEEP DDQDAPDEHE PSPSEDAPLY PHSPASQYQQ NNHVHGQPYT GPAAHHLNNP QKTGQRTQEN YEGNEEVSSP QMKDQ