Details for: CDC7

Gene ID: 8317

Symbol: CDC7

Ensembl ID: ENSG00000097046

Description: cell division cycle 7

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 56.0609
    Cell Significance Index: -8.7200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 44.4325
    Cell Significance Index: -11.2700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 9.7246
    Cell Significance Index: -11.9900
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 4.8304
    Cell Significance Index: -12.9400
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.1500
    Cell Significance Index: -12.4300
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.2149
    Cell Significance Index: 120.1900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.8274
    Cell Significance Index: 46.4300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.7636
    Cell Significance Index: 16.7200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.7536
    Cell Significance Index: 21.0600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.7356
    Cell Significance Index: 139.9900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.6792
    Cell Significance Index: 136.2500
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.6627
    Cell Significance Index: 8.2200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.6142
    Cell Significance Index: 99.8900
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.5558
    Cell Significance Index: 60.4500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4805
    Cell Significance Index: 95.3500
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.4516
    Cell Significance Index: 27.1100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3931
    Cell Significance Index: 140.9900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.3073
    Cell Significance Index: 18.8900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.2919
    Cell Significance Index: 18.4000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2786
    Cell Significance Index: 251.6000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.2519
    Cell Significance Index: 11.1400
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 0.2375
    Cell Significance Index: 3.8100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.2319
    Cell Significance Index: 8.7800
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.2208
    Cell Significance Index: 5.3000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1892
    Cell Significance Index: 4.7300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.1720
    Cell Significance Index: 20.2800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1555
    Cell Significance Index: 4.4800
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1540
    Cell Significance Index: 106.5000
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: 0.1258
    Cell Significance Index: 4.3700
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 0.0975
    Cell Significance Index: 2.0900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0617
    Cell Significance Index: 4.2700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0491
    Cell Significance Index: 1.3200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0399
    Cell Significance Index: 21.8000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0363
    Cell Significance Index: 4.2300
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0358
    Cell Significance Index: 15.8100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 0.0217
    Cell Significance Index: 1.4600
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0196
    Cell Significance Index: 0.4200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0087
    Cell Significance Index: 5.5600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0037
    Cell Significance Index: 0.1300
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0001
    Cell Significance Index: 0.2800
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0002
    Cell Significance Index: -0.3500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0033
    Cell Significance Index: -0.4500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0038
    Cell Significance Index: -5.8900
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0054
    Cell Significance Index: -0.2800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0057
    Cell Significance Index: -0.2600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0061
    Cell Significance Index: -2.7900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0085
    Cell Significance Index: -0.1800
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0086
    Cell Significance Index: -1.2500
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0087
    Cell Significance Index: -1.5700
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0093
    Cell Significance Index: -0.1600
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0104
    Cell Significance Index: -14.0900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0141
    Cell Significance Index: -10.6700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0160
    Cell Significance Index: -11.7200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0180
    Cell Significance Index: -0.4800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0183
    Cell Significance Index: -13.5700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0230
    Cell Significance Index: -14.3800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0237
    Cell Significance Index: -2.9100
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0240
    Cell Significance Index: -13.5400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0309
    Cell Significance Index: -0.9900
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0338
    Cell Significance Index: -9.7300
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.0413
    Cell Significance Index: -0.2800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0430
    Cell Significance Index: -2.2600
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0553
    Cell Significance Index: -7.0900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0667
    Cell Significance Index: -3.1100
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0677
    Cell Significance Index: -4.1500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0689
    Cell Significance Index: -14.5100
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0694
    Cell Significance Index: -11.8500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0750
    Cell Significance Index: -1.2600
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0758
    Cell Significance Index: -0.4500
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0761
    Cell Significance Index: -5.3800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0786
    Cell Significance Index: -8.0300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0803
    Cell Significance Index: -6.1600
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0854
    Cell Significance Index: -1.0700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0898
    Cell Significance Index: -11.6000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0931
    Cell Significance Index: -2.4900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0938
    Cell Significance Index: -4.4100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.1035
    Cell Significance Index: -6.6800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1129
    Cell Significance Index: -12.9300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1147
    Cell Significance Index: -11.9400
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1156
    Cell Significance Index: -3.3000
  • Cell Name: glioblast (CL0000030)
    Fold Change: -0.1226
    Cell Significance Index: -0.7700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1234
    Cell Significance Index: -2.6200
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.1271
    Cell Significance Index: -2.6600
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1285
    Cell Significance Index: -2.5400
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.1397
    Cell Significance Index: -3.5700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1460
    Cell Significance Index: -4.6500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.1466
    Cell Significance Index: -2.0000
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1515
    Cell Significance Index: -4.9600
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1530
    Cell Significance Index: -12.1200
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1594
    Cell Significance Index: -3.2000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1613
    Cell Significance Index: -12.0200
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1655
    Cell Significance Index: -2.3700
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: -0.1665
    Cell Significance Index: -1.8100
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.1669
    Cell Significance Index: -1.9900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1784
    Cell Significance Index: -4.6900
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.1917
    Cell Significance Index: -2.4200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1958
    Cell Significance Index: -4.2300
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1976
    Cell Significance Index: -4.9300
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1991
    Cell Significance Index: -3.0000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2123
    Cell Significance Index: -7.4400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** CDC7 is a serine/threonine kinase that is involved in the regulation of the cell cycle, particularly during the G1/S transition and the initiation of DNA replication. Some key characteristics of CDC7 include: * Phosphorylation-dependent activation: CDC7 is phosphorylated upon binding to the pre-replicative complex, allowing it to activate downstream targets. * Kinase activity: CDC7 possesses kinase activity, which is essential for phosphorylating and activating downstream targets. * Expression in various cell types: CDC7 is significantly expressed in germ cells, mural cells, cardiac muscle myoblasts, and lymphoid lineage-restricted progenitor cells. * Role in cell cycle progression: CDC7 plays a critical role in regulating the G1/S transition and the initiation of DNA replication, allowing for the proper progression of the cell cycle. **Pathways and Functions** CDC7 is involved in several cellular pathways, including: * Activation of the pre-replicative complex: CDC7 binds to the pre-replicative complex, allowing it to phosphorylate and activate downstream targets. * DNA replication: CDC7 phosphorylates and activates downstream targets, such as CDK2 and Cdc6, which are essential for the initiation of DNA replication. * Cell cycle checkpoints: CDC7 is involved in the regulation of cell cycle checkpoints, including the G1/S transition and the G2/M transition. * Phosphorylation-dependent regulation: CDC7 phosphorylates and activates downstream targets, which in turn regulate the cell cycle. **Clinical Significance** Dysregulation of CDC7 has been implicated in several diseases, including: * Cancer: Overexpression or mutations in CDC7 have been found in various types of cancer, including breast, lung, and colon cancer. * Neurological disorders: CDC7 has been implicated in neurological disorders, such as Alzheimer's disease and Parkinson's disease. * Cardiovascular disease: CDC7 has been found to be involved in the regulation of cardiac muscle cell proliferation, and dysregulation of CDC7 has been implicated in cardiovascular disease. In summary, CDC7 is a critical regulator of the cell cycle, particularly during the G1/S transition and the initiation of DNA replication. Dysregulation of CDC7 has been implicated in several diseases, highlighting the importance of this gene in maintaining cellular homeostasis.

Genular Protein ID: 2442672157

Symbol: CDC7_HUMAN

Name: Cell division cycle 7-related protein kinase

UniProtKB Accession Codes:

O00311 D3DT31 O00558 Q5T5U5

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CORUM 1 CTD 1 ChEBI 13 ChEMBL 1 ChiTaRS 1 DIP 1 DNASU 1 DisGeNET 1 EC 2 EMBL 10 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 19 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 9 PDBsum 9 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 3 RefSeq 4 Rhea 8 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9250678

Title: Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7.

PubMed ID: 9250678

DOI: 10.1093/emboj/16.14.4340

PubMed ID: 9573348

Title: A human homolog of the yeast CDC7 gene is overexpressed in some tumors and transformed cell lines.

PubMed ID: 9573348

DOI: 10.1016/s0378-1119(98)00094-8

PubMed ID: 9405610

Title: Identification and characterization of a human protein kinase related to budding yeast Cdc7p.

PubMed ID: 9405610

DOI: 10.1073/pnas.94.26.14320

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10373557

Title: A novel growth- and cell cycle-regulated protein, ASK, activates human Cdc7-related kinase and is essential for G1/S transition in mammalian cells.

PubMed ID: 10373557

DOI: 10.1128/mcb.19.7.5083

PubMed ID: 12065429

Title: Drf1, a novel regulatory subunit for human Cdc7 kinase.

PubMed ID: 12065429

DOI: 10.1093/emboj/cdf290

PubMed ID: 15668232

Title: A second human Dbf4/ASK-related protein, Drf1/ASKL1, is required for efficient progression of S and M phases.

PubMed ID: 15668232

DOI: 10.1074/jbc.m411653200

PubMed ID: 17062569

Title: Cdc7 is an active kinase in human cancer cells undergoing replication stress.

PubMed ID: 17062569

DOI: 10.1074/jbc.m604457200

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 28112733

Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.

PubMed ID: 28112733

DOI: 10.1038/nsmb.3366

PubMed ID: 27401717

Title: Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells.

PubMed ID: 27401717

DOI: 10.1038/ncomms12135

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

Sequence Information:

  • Length: 574
  • Mass: 63888
  • Checksum: 90D549BEE20AE583
  • Sequence:
    • MEASLGIQMD EPMAFSPQRD RFQAEGSLKK NEQNFKLAGV KKDIEKLYEA VPQLSNVFKI 
EDKIGEGTFS SVYLATAQLQ VGPEEKIALK HLIPTSHPIR IAAELQCLTV AGGQDNVMGV 
KYCFRKNDHV VIAMPYLEHE SFLDILNSLS FQEVREYMLN LFKALKRIHQ FGIVHRDVKP 
SNFLYNRRLK KYALVDFGLA QGTHDTKIEL LKFVQSEAQQ ERCSQNKSHI ITGNKIPLSG 
PVPKELDQQS TTKASVKRPY TNAQIQIKQG KDGKEGSVGL SVQRSVFGER NFNIHSSISH 
ESPAVKLMKQ SKTVDVLSRK LATKKKAIST KVMNSAVMRK TASSCPASLT CDCYATDKVC 
SICLSRRQQV APRAGTPGFR APEVLTKCPN QTTAIDMWSA GVIFLSLLSG RYPFYKASDD 
LTALAQIMTI RGSRETIQAA KTFGKSILCS KEVPAQDLRK LCERLRGMDS STPKLTSDIQ 
GHASHQPAIS EKTDHKASCL VQTPPGQYSG NSFKKGDSNS CEHCFDEYNT NLEGWNEVPD 
EAYDLLDKLL DLNPASRITA EEALLHPFFK DMSL

Genular Protein ID: 1179132005

Symbol: B2R6V2_HUMAN

Name: N/A

UniProtKB Accession Codes:

B2R6V2

Database IDs:

ARBA 3 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChEBI 1 DNASU 1 DisGeNET 1 EMBL 2 GO 3 Gene3D 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 1 SMART 1 SUPFAM 1

Sequence Information:

  • Length: 574
  • Mass: 63830
  • Checksum: 9177D9CC73DAE54C
  • Sequence:
    • MEASLGIQMD EPMAFSPQRD RFQAEGSLKK NEQNFKLAGV KKDIEKLYEA VPQLSNVFKI 
EDKIGEGTFS SVYLATAQLQ VGPEEKIALK HLIPTSHPIR IAAELQCLTV AGGQDNVMGV 
KYCFRKNDHV VIAMPYLEHE SFLDILNSLS FQEVREYMLN LFKALKRIHQ FGIVHRDVKP 
SNFLYNRRLK KYALVGFGLA QGTHDTKIEL LKFVQSEAQQ ERCSQNKSHI ITGNKIPLSG 
PVPKELDQQS TTKASVKRPY TNAQIQIKQG KDGKEGSVGL SVQRSVFGER NFNIHSSISH 
ESPAVKLMKQ SKTVDVLSRK LATKKKAIST KVMNSAVMRK TASSCPASLT CDCYATDKVC 
SICLSRRQQV APRAGTPGFR APEVLTKCPN QTTAIDMWSA GVIFLSLLSG RYPFYKASDD 
LTALAQIMTI RGSRETIQAA KTFGKSILCS KEVPAQDLRK LCERLRGMDS STPKLTSDIQ 
GHASHQPAIS EKTDHKASCL VQTPPGQYSG NSFKKGDSNS CEHCFDEYNT NLEGWNEVPD 
EAYDLLDKLL DLNPASRITA EEALLHPFFK DMSL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.