Details for: H2AC13

Gene ID: 8329

Symbol: H2AC13

Ensembl ID: ENSG00000196747

Description: H2A clustered histone 13

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 9.3833
    Cell Significance Index: -2.3800
  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 7.9720
    Cell Significance Index: -1.2400
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 1.8898
    Cell Significance Index: -2.3300
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.4503
    Cell Significance Index: 85.6900
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.4168
    Cell Significance Index: 41.2400
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.3878
    Cell Significance Index: 8.0500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.3645
    Cell Significance Index: 5.2200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 0.3639
    Cell Significance Index: 23.4800
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.3340
    Cell Significance Index: 36.3300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.3033
    Cell Significance Index: 8.7400
  • Cell Name: neuroendocrine cell (CL0000165)
    Fold Change: 0.2977
    Cell Significance Index: 3.7700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2852
    Cell Significance Index: 46.3900
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.2485
    Cell Significance Index: 29.3000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.2236
    Cell Significance Index: 201.9000
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2132
    Cell Significance Index: 12.8000
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: 0.1563
    Cell Significance Index: 4.5900
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1400
    Cell Significance Index: 9.6800
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 0.1295
    Cell Significance Index: 0.6300
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 0.1284
    Cell Significance Index: 3.3800
  • Cell Name: skeletal muscle myoblast (CL0000515)
    Fold Change: 0.1122
    Cell Significance Index: 1.2200
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0965
    Cell Significance Index: 3.3900
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.0855
    Cell Significance Index: 1.2000
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: 0.0764
    Cell Significance Index: 1.0600
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.0750
    Cell Significance Index: 1.5700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0679
    Cell Significance Index: 1.4700
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.0628
    Cell Significance Index: 2.0100
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 0.0514
    Cell Significance Index: 0.5200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.0467
    Cell Significance Index: 0.7000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0397
    Cell Significance Index: 21.6600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.0397
    Cell Significance Index: 2.0600
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 0.0251
    Cell Significance Index: 0.2600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: 0.0215
    Cell Significance Index: 0.5500
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0214
    Cell Significance Index: 0.9700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0142
    Cell Significance Index: 0.3600
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.0139
    Cell Significance Index: 0.2100
  • Cell Name: sensory neuron (CL0000101)
    Fold Change: 0.0123
    Cell Significance Index: 0.0700
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: 0.0101
    Cell Significance Index: 0.1100
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.0089
    Cell Significance Index: 0.1900
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0062
    Cell Significance Index: 0.1700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0013
    Cell Significance Index: 0.5800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0006
    Cell Significance Index: -0.0400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0007
    Cell Significance Index: -0.1300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0009
    Cell Significance Index: -0.5200
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0032
    Cell Significance Index: -2.4400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0044
    Cell Significance Index: -2.7700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0044
    Cell Significance Index: -0.6100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0053
    Cell Significance Index: -0.5400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0053
    Cell Significance Index: -2.3900
  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: -0.0055
    Cell Significance Index: -0.0300
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.0063
    Cell Significance Index: -0.0700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0064
    Cell Significance Index: -1.8500
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0066
    Cell Significance Index: -1.3100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0079
    Cell Significance Index: -1.0100
  • Cell Name: respiratory epithelial cell (CL0002368)
    Fold Change: -0.0083
    Cell Significance Index: -0.0500
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0093
    Cell Significance Index: -0.5700
  • Cell Name: germ cell (CL0000586)
    Fold Change: -0.0093
    Cell Significance Index: -0.0700
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0099
    Cell Significance Index: -0.4300
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0114
    Cell Significance Index: -1.9500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0125
    Cell Significance Index: -2.5000
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0155
    Cell Significance Index: -1.7800
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0158
    Cell Significance Index: -0.2700
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.0162
    Cell Significance Index: -0.2000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0174
    Cell Significance Index: -2.1400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0189
    Cell Significance Index: -2.4400
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -0.0207
    Cell Significance Index: -0.2700
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: -0.0230
    Cell Significance Index: -0.2600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0282
    Cell Significance Index: -1.4800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0296
    Cell Significance Index: -0.9700
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0298
    Cell Significance Index: -2.2200
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: -0.0300
    Cell Significance Index: -0.3800
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: -0.0355
    Cell Significance Index: -0.4500
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0366
    Cell Significance Index: -1.7200
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: -0.0385
    Cell Significance Index: -0.2800
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: -0.0400
    Cell Significance Index: -0.3400
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0423
    Cell Significance Index: -1.1300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0429
    Cell Significance Index: -2.0000
  • Cell Name: DN4 thymocyte (CL0000808)
    Fold Change: -0.0445
    Cell Significance Index: -0.3400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0458
    Cell Significance Index: -1.3500
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: -0.0475
    Cell Significance Index: -0.6800
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0479
    Cell Significance Index: -1.7600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0496
    Cell Significance Index: -2.2000
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0500
    Cell Significance Index: -1.3600
  • Cell Name: PP cell (CL0000696)
    Fold Change: -0.0521
    Cell Significance Index: -0.5300
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0573
    Cell Significance Index: -1.4300
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0622
    Cell Significance Index: -2.1600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0634
    Cell Significance Index: -2.2200
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0653
    Cell Significance Index: -2.0800
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: -0.0699
    Cell Significance Index: -0.9800
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.0759
    Cell Significance Index: -0.7400
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.0765
    Cell Significance Index: -1.1300
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0801
    Cell Significance Index: -2.0400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0836
    Cell Significance Index: -1.1400
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0839
    Cell Significance Index: -2.1000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0848
    Cell Significance Index: -2.4300
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: -0.0857
    Cell Significance Index: -0.8700
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: -0.0866
    Cell Significance Index: -0.6800
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0876
    Cell Significance Index: -0.5200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0882
    Cell Significance Index: -2.2000
  • Cell Name: pro-B cell (CL0000826)
    Fold Change: -0.0884
    Cell Significance Index: -0.9500
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0916
    Cell Significance Index: -1.3300

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** H2A13 is a histone protein that is part of the H2A cluster, which accounts for approximately 15% of the total histone content in mammalian cells. This gene is characterized by its ability to interact with various proteins and enzymes, including acetyltransferases, deacetylases, and ubiquitin ligases, which are essential for chromatin regulation. The unique structure of H2A13 allows it to form heterochromatin, a compact chromatin structure that is typically associated with gene silencing. **Pathways and Functions:** H2A13 is involved in multiple pathways that govern chromatin structure and function, including: 1. **Chromatin Organization**: H2A13 plays a critical role in the formation and maintenance of heterochromatin, which is essential for regulating gene expression. 2. **Histone Modification**: H2A13 is a substrate for various histone-modifying enzymes, including acetyltransferases and deacetylases, which regulate chromatin structure and function. 3. **Protein Binding**: H2A13 interacts with multiple proteins, including transcription factors, chromatin remodeling complexes, and histone-modifying enzymes, which regulate gene expression and chromatin structure. 4. **Post-Translational Modification**: H2A13 undergoes various post-translational modifications, including phosphorylation, ubiquitination, and acetylation, which regulate its function and interactions. **Clinical Significance:** Dysregulation of H2A13 has been implicated in various diseases, including: 1. **Autoimmune Disorders**: Altered expression and function of H2A13 have been linked to autoimmune diseases, such as multiple sclerosis and rheumatoid arthritis. 2. **Cancer**: Aberrant expression and modification of H2A13 have been observed in various cancers, including breast, lung, and colon cancer. 3. **Neurological Disorders**: H2A13 has been implicated in neurological disorders, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. In conclusion, H2A Clustered Histone 13 is a complex gene that plays a critical role in chromatin regulation and immune response. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the mechanisms of H2A13 and its potential as a therapeutic target.

Genular Protein ID: 153980397

Symbol: H2A1_HUMAN

Name: Histone H2A type 1

UniProtKB Accession Codes:

P0C0S8 P02261 Q2M1R2 Q76PA6

Database IDs:

ABCD 1 AGR 5 AlphaFoldDB 1 Antibodypedia 5 Bgee 1 BioGRID 5 BioGRID-ORCS 5 BioMuta 1 CCDS 5 CDD 1 CTD 5 ChiTaRS 2 DIP 1 DMDM 1 DNASU 1 DisGeNET 5 EMBL 21 EMDB 23 Ensembl 5 EvolutionaryTrace 1 ExpressionAtlas 1 GO 8 Gene3D 1 GeneCards 5 GeneTree 1 GeneWiki 5 GlyGen 1 HGNC 5 HOGENOM 1 HPA 5 InParanoid 1 IntAct 1 InterPro 5 KEGG 5 MANE-Select 5 MIM 5 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 5 OrthoDB 1 PANTHER 2 PDB 23 PDBsum 23 PIR 1 PRIDE 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 Pumba 1 RNAct 1 Reactome 8 RefSeq 5 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TopDownProteomics 1 TreeFam 1 UCSC 1 VEuPathDB 5 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9439656

Title: The human histone gene cluster at the D6S105 locus.

PubMed ID: 9439656

DOI: 10.1007/s004390050630

PubMed ID: 10064132

Title: The human H2A and H2B histone gene complement.

PubMed ID: 10064132

DOI: 10.1515/bc.1999.002

PubMed ID: 1768865

Title: A novel divergently transcribed human histone H2A/H2B gene pair.

PubMed ID: 1768865

DOI: 10.3109/10425179109020799

PubMed ID: 8179821

Title: The relative expression of human histone H2A genes is similar in different types of proliferating cells.

PubMed ID: 8179821

DOI: 10.1089/dna.1994.13.161

PubMed ID: 12408966

Title: The human and mouse replication-dependent histone genes.

PubMed ID: 12408966

DOI: 10.1016/s0888-7543(02)96850-3

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 7410338

Title: Human spleen histone H2A. Isolation and four variant sequences.

PubMed ID: 7410338

PubMed ID: 11709551

Title: Global regulation of post-translational modifications on core histones.

PubMed ID: 11709551

DOI: 10.1074/jbc.m107894200

PubMed ID: 15078818

Title: Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo.

PubMed ID: 15078818

DOI: 10.1101/gad.1184604

PubMed ID: 15010469

Title: Phosphorylation of histone H2A inhibits transcription on chromatin templates.

PubMed ID: 15010469

DOI: 10.1074/jbc.m400099200

PubMed ID: 15386022

Title: Role of histone H2A ubiquitination in Polycomb silencing.

PubMed ID: 15386022

DOI: 10.1038/nature02985

PubMed ID: 15823041

Title: Deimination of histone H2A and H4 at arginine 3 in HL-60 granulocytes.

PubMed ID: 15823041

DOI: 10.1021/bi047505c

PubMed ID: 16359901

Title: Role of Bmi-1 and Ring1A in H2A ubiquitylation and Hox gene silencing.

PubMed ID: 16359901

DOI: 10.1016/j.molcel.2005.12.002

PubMed ID: 16702407

Title: DNA damage triggers nucleotide excision repair-dependent monoubiquitylation of histone H2A.

PubMed ID: 16702407

DOI: 10.1101/gad.373706

PubMed ID: 16457589

Title: Precise characterization of human histones in the H2A gene family by top down mass spectrometry.

PubMed ID: 16457589

DOI: 10.1021/pr050269n

PubMed ID: 18001824

Title: RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.

PubMed ID: 18001824

DOI: 10.1016/j.cell.2007.09.040

PubMed ID: 18001825

Title: RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly.

PubMed ID: 18001825

DOI: 10.1016/j.cell.2007.09.041

PubMed ID: 19203578

Title: The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.

PubMed ID: 19203578

DOI: 10.1016/j.cell.2008.12.042

PubMed ID: 19203579

Title: RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins.

PubMed ID: 19203579

DOI: 10.1016/j.cell.2008.12.041

PubMed ID: 21925322

Title: Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification.

PubMed ID: 21925322

DOI: 10.1016/j.cell.2011.08.008

PubMed ID: 22980979

Title: RNF168 ubiquitinates K13-15 on H2A/H2AX to drive DNA Damage signaling.

PubMed ID: 22980979

DOI: 10.1016/j.cell.2012.08.005

PubMed ID: 22713238

Title: A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase.

PubMed ID: 22713238

DOI: 10.4161/cc.20919

PubMed ID: 22389435

Title: Lysine succinylation and lysine malonylation in histones.

PubMed ID: 22389435

DOI: 10.1074/mcp.m111.015875

PubMed ID: 24140421

Title: VprBP has intrinsic kinase activity targeting histone H2A and represses gene transcription.

PubMed ID: 24140421

DOI: 10.1016/j.molcel.2013.09.017

PubMed ID: 24681537

Title: Lysine 2-hydroxyisobutyrylation is a widely distributed active histone mark.

PubMed ID: 24681537

DOI: 10.1038/nchembio.1497

PubMed ID: 24352239

Title: Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification.

PubMed ID: 24352239

DOI: 10.1038/nature12819

PubMed ID: 25470042

Title: TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein.

PubMed ID: 25470042

DOI: 10.1038/nature13955

PubMed ID: 27083998

Title: USP51 deubiquitylates H2AK13,15ub and regulates DNA damage response.

PubMed ID: 27083998

DOI: 10.1101/gad.271841.115

PubMed ID: 27105115

Title: Metabolic regulation of gene expression by histone lysine beta-hydroxybutyrylation.

PubMed ID: 27105115

DOI: 10.1016/j.molcel.2016.03.036

PubMed ID: 31542297

Title: Glutarylation of histone H4 lysine 91 regulates chromatin dynamics.

PubMed ID: 31542297

DOI: 10.1016/j.molcel.2019.08.018

PubMed ID: 32911481

Title: The molecular basis of tight nuclear tethering and inactivation of cGAS.

PubMed ID: 32911481

DOI: 10.1038/s41586-020-2749-z

PubMed ID: 32913000

Title: Structural basis of nucleosome-dependent cGAS inhibition.

PubMed ID: 32913000

DOI: 10.1126/science.abd0609

PubMed ID: 35390161

Title: Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity.

PubMed ID: 35390161

DOI: 10.1093/nar/gkac198

Sequence Information:

  • Length: 130
  • Mass: 14091
  • Checksum: 48DD539793FE8256
  • Sequence:
    • MSGRGKQGGK ARAKAKTRSS RAGLQFPVGR VHRLLRKGNY AERVGAGAPV YLAAVLEYLT 
AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGK VTIAQGGVLP NIQAVLLPKK 
TESHHKAKGK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.