Details for: PDE8B

Gene ID: 8622

Symbol: PDE8B

Ensembl ID: ENSG00000113231

Description: phosphodiesterase 8B

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 126.5556
    Cell Significance Index: -32.1000
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 26.1729
    Cell Significance Index: -32.2700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 6.6638
    Cell Significance Index: 1917.3600
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 4.7812
    Cell Significance Index: 50.8000
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 3.3108
    Cell Significance Index: 1187.5200
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 3.2579
    Cell Significance Index: 20.1000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 3.0342
    Cell Significance Index: 134.2100
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 2.8513
    Cell Significance Index: 107.9700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.3682
    Cell Significance Index: 475.0600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.9510
    Cell Significance Index: 42.7200
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.8339
    Cell Significance Index: 3.6300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 0.5096
    Cell Significance Index: 31.3200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.5093
    Cell Significance Index: 39.0900
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.4854
    Cell Significance Index: 27.2400
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.3013
    Cell Significance Index: 14.0500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 0.2452
    Cell Significance Index: 5.8800
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2216
    Cell Significance Index: 42.1800
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1550
    Cell Significance Index: 15.3300
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.1276
    Cell Significance Index: 115.2600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.1229
    Cell Significance Index: 4.3200
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0993
    Cell Significance Index: 16.1600
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.0608
    Cell Significance Index: 6.6100
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.0473
    Cell Significance Index: 0.4900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.0431
    Cell Significance Index: 0.5400
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.0123
    Cell Significance Index: 0.7400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0108
    Cell Significance Index: 1.9500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0040
    Cell Significance Index: -0.0800
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0045
    Cell Significance Index: -8.5500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0056
    Cell Significance Index: -4.1800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0134
    Cell Significance Index: -7.5900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0152
    Cell Significance Index: -28.0700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0167
    Cell Significance Index: -10.4000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0180
    Cell Significance Index: -27.7100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0223
    Cell Significance Index: -30.3800
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.0267
    Cell Significance Index: -0.3600
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0280
    Cell Significance Index: -17.7900
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0286
    Cell Significance Index: -20.9700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0357
    Cell Significance Index: -1.0300
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0389
    Cell Significance Index: -29.4200
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0406
    Cell Significance Index: -22.1700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0443
    Cell Significance Index: -20.1000
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0562
    Cell Significance Index: -9.5900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0583
    Cell Significance Index: -12.2900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0592
    Cell Significance Index: -6.7800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0611
    Cell Significance Index: -1.3200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0745
    Cell Significance Index: -4.5700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0812
    Cell Significance Index: -35.9100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0876
    Cell Significance Index: -1.8600
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1024
    Cell Significance Index: -3.2600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1065
    Cell Significance Index: -1.5300
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -0.1085
    Cell Significance Index: -2.3500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.1088
    Cell Significance Index: -15.8200
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.1292
    Cell Significance Index: -25.6400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1375
    Cell Significance Index: -2.7600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.1433
    Cell Significance Index: -17.6300
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.1689
    Cell Significance Index: -23.2000
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.1698
    Cell Significance Index: -11.7500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1764
    Cell Significance Index: -5.6500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1920
    Cell Significance Index: -22.3800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1994
    Cell Significance Index: -25.7600
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.2051
    Cell Significance Index: -24.1900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.2150
    Cell Significance Index: -4.4600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.2209
    Cell Significance Index: -22.5600
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.2442
    Cell Significance Index: -27.8800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2743
    Cell Significance Index: -8.9800
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -0.2770
    Cell Significance Index: -4.7900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2780
    Cell Significance Index: -17.9300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.2795
    Cell Significance Index: -20.8300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2810
    Cell Significance Index: -17.7100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2941
    Cell Significance Index: -8.2200
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.2959
    Cell Significance Index: -6.3300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2966
    Cell Significance Index: -30.8800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.3154
    Cell Significance Index: -40.4400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.3211
    Cell Significance Index: -25.4300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.3256
    Cell Significance Index: -14.7600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.3545
    Cell Significance Index: -18.6100
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.3565
    Cell Significance Index: -6.1100
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.3611
    Cell Significance Index: -18.8100
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.3659
    Cell Significance Index: -19.0100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.4306
    Cell Significance Index: -10.7400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.4509
    Cell Significance Index: -21.1900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.4669
    Cell Significance Index: -11.6700
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.4918
    Cell Significance Index: -9.6800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.4967
    Cell Significance Index: -7.4900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.5034
    Cell Significance Index: -35.6000
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.5391
    Cell Significance Index: -5.1100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.5472
    Cell Significance Index: -19.1700
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.5620
    Cell Significance Index: -15.0600
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.5789
    Cell Significance Index: -25.1700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.5822
    Cell Significance Index: -12.4000
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.5966
    Cell Significance Index: -4.5900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.6046
    Cell Significance Index: -15.5400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.6603
    Cell Significance Index: -24.2400
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.6722
    Cell Significance Index: -14.0300
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.6935
    Cell Significance Index: -7.5600
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.7046
    Cell Significance Index: -8.2200
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.7066
    Cell Significance Index: -14.0900
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.7112
    Cell Significance Index: -18.7000
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.7155
    Cell Significance Index: -11.7900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.7485
    Cell Significance Index: -26.0100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** PDE8B is a high-affinity cAMP-specific phosphodiesterase, meaning it preferentially hydrolyzes cAMP, a key second messenger involved in cellular signaling. Unlike other phosphodiesterases, PDE8B is insensitive to IBMX, a non-selective phosphodiesterase inhibitor. This specificity suggests that PDE8B plays a critical role in regulating cAMP-mediated signaling pathways. Additionally, PDE8B is localized to the cytosol and nucleus, indicating its involvement in both cytoplasmic and nuclear signaling processes. **Pathways and Functions:** PDE8B is involved in various signaling pathways, including: 1. **Gαs Signaling Events**: PDE8B degrades cAMP, a key second messenger in Gαs-mediated signaling. This pathway is crucial for regulating various cellular processes, including glucose metabolism and insulin secretion. 2. **Camp-mediated Signaling**: PDE8B's ability to hydrolyze cAMP suggests its involvement in camp-mediated signaling, which regulates gene expression, cell growth, and differentiation. 3. **Neurotransmission**: PDE8B is expressed in neurons, including GABAergic cortical interneurons, suggesting its role in regulating neurotransmission and neuronal function. 4. **Immune Regulation**: PDE8B is expressed in immune cells, including astrocytes and vascular leptomeningeal cells, indicating its involvement in immune responses and inflammation. **Clinical Significance:** PDE8B's involvement in various signaling pathways and its expression in immune cells make it a promising target for therapeutic interventions in diseases characterized by dysregulation of cAMP signaling, such as: 1. **Diabetes**: PDE8B's role in glucose metabolism and insulin secretion makes it a potential target for treating type 2 diabetes. 2. **Neurological Disorders**: PDE8B's involvement in neurotransmission and neuronal function suggests its potential role in treating neurological disorders, such as anxiety, depression, and Parkinson's disease. 3. **Inflammatory Diseases**: PDE8B's expression in immune cells and its role in regulating immune responses make it a potential target for treating inflammatory diseases, such as multiple sclerosis and rheumatoid arthritis. In conclusion, PDE8B is a complex enzyme with diverse roles in signaling pathways, gene regulation, and immune responses. Further research is needed to fully elucidate its functions and potential therapeutic applications.

Genular Protein ID: 3817434432

Symbol: PDE8B_HUMAN

Name: High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B

UniProtKB Accession Codes:

O95263 Q5J7V7 Q86XK8 Q8IUJ7 Q8IUJ8 Q8IUJ9 Q8IUK0 Q8N3T2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BindingDB 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 2 CTD 1 ChEBI 10 ChEMBL 1 ChiTaRS 1 DNASU 1 DisGeNET 1 DrugBank 2 DrugCentral 1 EC 1 EMBL 14 Ensembl 6 ExpressionAtlas 1 GO 15 Gene3D 2 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MANE-Select 1 MIM 5 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NCBIfam 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PIR 1 PRINTS 1 PRO 1 PROSITE 3 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 6 Pumba 1 RNAct 1 Reactome 1 RefSeq 5 Rhea 1 SMART 2 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 12372422

Title: Genomic organization, chromosomal localization, and alternative splicing of the human phosphodiesterase 8B gene.

PubMed ID: 12372422

DOI: 10.1016/s0006-291x(02)02371-9

PubMed ID: 12681444

Title: Comparison of enzymatic characterization and gene organization of cyclic nucleotide phosphodiesterase 8 family in humans.

PubMed ID: 12681444

DOI: 10.1016/s0898-6568(02)00146-8

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9784418

Title: Molecular cloning and characterization of human PDE8B, a novel thyroid-specific isozyme of 3',5'-cyclic nucleotide phosphodiesterase.

PubMed ID: 9784418

DOI: 10.1006/bbrc.1998.9379

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20085714

Title: Autosomal-dominant striatal degeneration is caused by a mutation in the phosphodiesterase 8B gene.

PubMed ID: 20085714

DOI: 10.1016/j.ajhg.2009.12.003

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 18431404

Title: A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex.

PubMed ID: 18431404

DOI: 10.1038/ejhg.2008.85

Sequence Information:

  • Length: 885
  • Mass: 98979
  • Checksum: DB4F763E51F745A3
  • Sequence:
    • MGCAPSIHVS QSGVIYCRDS DESSSPRQTT SVSQGPAAPL PGLFVQTDAA DAIPPSRASG 
PPSVARVRRA RTELGSGSSA GSAAPAATTS RGRRRHCCSS AEAETQTCYT SVKQVSSAEV 
RIGPMRLTQD PIQVLLIFAK EDSQSDGFWW ACDRAGYRCN IARTPESALE CFLDKHHEII 
VIDHRQTQNF DAEAVCRSIR ATNPSEHTVI LAVVSRVSDD HEEASVLPLL HAGFNRRFME 
NSSIIACYNE LIQIEHGEVR SQFKLRACNS VFTALDHCHE AIEITSDDHV IQYVNPAFER 
MMGYHKGELL GKELADLPKS DKNRADLLDT INTCIKKGKE WQGVYYARRK SGDSIQQHVK 
ITPVIGQGGK IRHFVSLKKL CCTTDNNKQI HKIHRDSGDN SQTEPHSFRY KNRRKESIDV 
KSISSRGSDA PSLQNRRYPS MARIHSMTIE APITKVINII NAAQENSPVT VAEALDRVLE 
ILRTTELYSP QLGTKDEDPH TSDLVGGLMT DGLRRLSGNE YVFTKNVHQS HSHLAMPITI 
NDVPPCISQL LDNEESWDFN IFELEAITHK RPLVYLGLKV FSRFGVCEFL NCSETTLRAW 
FQVIEANYHS SNAYHNSTHA ADVLHATAFF LGKERVKGSL DQLDEVAALI AATVHDVDHP 
GRTNSFLCNA GSELAVLYND TAVLESHHTA LAFQLTVKDT KCNIFKNIDR NHYRTLRQAI 
IDMVLATEMT KHFEHVNKFV NSINKPMAAE IEGSDCECNP AGKNFPENQI LIKRMMIKCA 
DVANPCRPLD LCIEWAGRIS EEYFAQTDEE KRQGLPVVMP VFDRNTCSIP KSQISFIDYF 
ITDMFDAWDA FAHLPALMQH LADNYKHWKT LDDLKCKSLR LPSDS

Genular Protein ID: 3924232548

Symbol: B3KN77_HUMAN

Name: N/A

UniProtKB Accession Codes:

B3KN77

Database IDs:

ARBA 5 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 2 CTD 1 ChEBI 10 DNASU 1 DisGeNET 1 EMBL 2 GO 4 Gene3D 2 InterPro 7 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PIRSR 3 PRINTS 1 PROSITE 3 PeptideAtlas 1 Pfam 2 RefSeq 5 RuleBase 1 SAM 1 SMART 1 SUPFAM 2 UniPathway 1

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 585
  • Mass: 66201
  • Checksum: 137E78512C0EB5DE
  • Sequence:
    • MMGYHKGELL GKELADLPKS DKNRADLLDT INTCIKKGKE WQGVYYARRK SGDSIQQHVK 
ITPVIGQGGK IRHFVSLKKL CCTTDNNKQI HKIHRDSGDN SQTEPHSFRY KNRRKESIDV 
KSISSRGSDA PSLQNRRYPS MARIHSMTIE APITKVINII NAAQENSPVT VAEALDRVLE 
ILRTTELYSP QLGTKDEDPH TSDLVGGLMT DGLRRLSGNE YVFTKNVHQS HSHLAMPITI 
NDVPPCISQL LDNEESWDFN IFELEAITHK RPLVYLGLKV FSRFGVCEFL NCSETTLRAW 
FQVIEANYHS SNAYHNSTHA ADVLHATAFF LGKERVKGSL DQLDEVAALI AATVHDVDHP 
GRTNSFLCNA GSELAVLYND TAVLESHHTA LAFQLTVKDT KCNIFKNIDR NHYRTLRQAI 
IDMVLATEMT KHFEHVNKFV NSINKPMAAE IEGSDCECNP AGKNFPENQI LIKRMMIKCA 
DVANPCRPLD LCIEWAGRIS EEYFAQTDEE KRQGLPVVMP VFDRNTCSIP KSQISFIDYF 
ITDMFDAWDA FAHLPALMQH LADNYKHWKT LDDLKCKSLR LPSDS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.