Details for: STXBP5L

Gene ID: 9515

Symbol: STXBP5L

Ensembl ID: ENSG00000145087

Description: syntaxin binding protein 5L

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: 9.6889
    Cell Significance Index: 276.4900
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: 7.6174
    Cell Significance Index: 512.2000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 7.5474
    Cell Significance Index: 129.3400
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 7.1122
    Cell Significance Index: 314.5900
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 6.5536
    Cell Significance Index: 248.1700
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 6.1007
    Cell Significance Index: 146.3100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 5.0914
    Cell Significance Index: 1826.2000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 4.5397
    Cell Significance Index: 279.0300
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 4.2265
    Cell Significance Index: -9.2500
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 4.2243
    Cell Significance Index: 32.4000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 3.7611
    Cell Significance Index: 754.4800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 3.7080
    Cell Significance Index: 227.3400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 3.4514
    Cell Significance Index: 2387.0900
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: 2.9236
    Cell Significance Index: 39.0000
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.6094
    Cell Significance Index: 32.3700
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: 1.5823
    Cell Significance Index: 20.5200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.9785
    Cell Significance Index: 54.9100
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.5733
    Cell Significance Index: 517.6500
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1461
    Cell Significance Index: 14.4500
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 0.1314
    Cell Significance Index: 1.2500
  • Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
    Fold Change: 0.1079
    Cell Significance Index: 1.1900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0784
    Cell Significance Index: 147.5800
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0338
    Cell Significance Index: 5.4900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0269
    Cell Significance Index: -49.5600
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0300
    Cell Significance Index: -13.6000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0345
    Cell Significance Index: -53.1500
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0379
    Cell Significance Index: -51.5700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0673
    Cell Significance Index: -49.8800
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0939
    Cell Significance Index: -3.3000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0958
    Cell Significance Index: -54.0300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.1097
    Cell Significance Index: -69.6800
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1441
    Cell Significance Index: -89.9800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.1445
    Cell Significance Index: -78.8900
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: -0.1522
    Cell Significance Index: -28.9700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.1569
    Cell Significance Index: -4.5200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.2373
    Cell Significance Index: -68.2700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.2551
    Cell Significance Index: -50.6400
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.2707
    Cell Significance Index: -29.4400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.2712
    Cell Significance Index: -7.5800
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.3560
    Cell Significance Index: -7.0400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.3665
    Cell Significance Index: -66.0700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3668
    Cell Significance Index: -77.2500
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.4393
    Cell Significance Index: -63.8600
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.4553
    Cell Significance Index: -4.9600
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.4739
    Cell Significance Index: -80.9200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.4963
    Cell Significance Index: -68.1600
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.4982
    Cell Significance Index: -7.1400
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.5485
    Cell Significance Index: -67.4400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.5720
    Cell Significance Index: -25.9300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.5813
    Cell Significance Index: -11.6700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.6032
    Cell Significance Index: -61.6200
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.7364
    Cell Significance Index: -15.6300
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.7396
    Cell Significance Index: -51.1500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.7424
    Cell Significance Index: -77.3000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.7440
    Cell Significance Index: -86.7100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.7524
    Cell Significance Index: -86.2000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.7806
    Cell Significance Index: -24.8600
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.8241
    Cell Significance Index: -26.9800
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: -0.8729
    Cell Significance Index: -7.5500
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.9017
    Cell Significance Index: -28.8800
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.9203
    Cell Significance Index: -55.2500
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -1.0009
    Cell Significance Index: -76.8100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.1441
    Cell Significance Index: -60.0700
  • Cell Name: neural cell (CL0002319)
    Fold Change: -1.1846
    Cell Significance Index: -13.8200
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -1.2729
    Cell Significance Index: -31.8200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -1.3082
    Cell Significance Index: -84.4000
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.3390
    Cell Significance Index: -29.0100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.3422
    Cell Significance Index: -47.0200
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -1.3612
    Cell Significance Index: -29.4100
  • Cell Name: neuron (CL0000540)
    Fold Change: -1.3725
    Cell Significance Index: -13.0100
  • Cell Name: myeloid dendritic cell (CL0000782)
    Fold Change: -1.4223
    Cell Significance Index: -11.1600
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -1.4450
    Cell Significance Index: -17.2800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -1.4541
    Cell Significance Index: -75.7400
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -1.4576
    Cell Significance Index: -36.3600
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.4626
    Cell Significance Index: -92.1800
  • Cell Name: hippocampal astrocyte (CL0002604)
    Fold Change: -1.4882
    Cell Significance Index: -20.8100
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: -1.6095
    Cell Significance Index: -20.3100
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.6417
    Cell Significance Index: -77.1600
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -1.7302
    Cell Significance Index: -36.1100
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -1.8044
    Cell Significance Index: -39.5100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -1.8205
    Cell Significance Index: -84.8800
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -1.8242
    Cell Significance Index: -12.3600
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -1.8324
    Cell Significance Index: -22.8500
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -1.9137
    Cell Significance Index: -49.1900
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -1.9459
    Cell Significance Index: -24.5600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.9578
    Cell Significance Index: -101.7000
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -2.0697
    Cell Significance Index: -44.2400
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -2.0925
    Cell Significance Index: -50.6900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -2.1067
    Cell Significance Index: -23.9300
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: -2.1573
    Cell Significance Index: -26.1500
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -2.2049
    Cell Significance Index: -31.3300
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -2.2229
    Cell Significance Index: -81.6000
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -2.2985
    Cell Significance Index: -45.2400
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: -2.4306
    Cell Significance Index: -42.0300
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -2.5034
    Cell Significance Index: -49.9200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -2.5752
    Cell Significance Index: -81.4500
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -2.5833
    Cell Significance Index: -89.7700
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -2.6542
    Cell Significance Index: -35.3800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -2.8386
    Cell Significance Index: -81.3700
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -2.8389
    Cell Significance Index: -58.8900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** STXBP5L is a protein-coding gene that is significantly expressed in various cell types, including neuronal brush cells, granule cells, macroglial cells, inhibitory interneurons, and CNS interneurons. The gene's products, STB5L, are known to interact with syntaxin, a key component of the SNARE complex, which is essential for the regulation of exocytosis and protein secretion. The gene's expression is highly specific, with a restricted pattern of expression in the CNS, suggesting a specialized role in neural function. **Pathways and Functions:** STXBP5L is involved in multiple pathways, including: 1. **Exocytosis:** STXBP5L regulates the fusion of vesicles with the plasma membrane, a critical step in the release of neurotransmitters and other signaling molecules. 2. **Protein Secretion:** The gene's products interact with syntaxin to facilitate the release of proteins from the endoplasmic reticulum. 3. **GTPase Activator Activity:** STXBP5L is a GTPase activator, which means it regulates the activity of GTP-binding proteins, including Ras and Rho. 4. **Myosin II Binding:** The gene's products interact with myosin II, a motor protein that regulates cell migration and cytoskeletal dynamics. **Clinical Significance:** Dysregulation of STXBP5L has been implicated in various neurological disorders, including: 1. **Autism Spectrum Disorder (ASD):** Studies have shown that individuals with ASD have altered expression of STXBP5L, suggesting a potential link between the gene and the pathogenesis of the disorder. 2. **Schizophrenia:** Research has identified a association between STXBP5L and schizophrenia, with altered expression of the gene in individuals with the disorder. 3. **Neurodegenerative Diseases:** STXBP5L has been implicated in the pathogenesis of neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease, where dysregulation of the gene's products may contribute to the development of symptoms. In conclusion, STXBP5L is a gene of significant importance in the regulation of exocytosis and protein secretion in the CNS. Dysregulation of the gene has been implicated in various neurological disorders, highlighting the need for further research into the gene's functions and its potential as a therapeutic target.

Genular Protein ID: 3898022225

Symbol: STB5L_HUMAN

Name: Syntaxin-binding protein 5-like

UniProtKB Accession Codes:

Q9Y2K9 Q4G1B4 Q6PIC3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 3 ExpressionAtlas 1 GO 9 Gene3D 2 GeneCards 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 3 SMART 1 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10231032

Title: Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

PubMed ID: 10231032

DOI: 10.1093/dnares/6.1.63

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14767561

Title: Identification and characterization of human LLGL4 gene and mouse Llgl4 gene in silico.

PubMed ID: 14767561

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

PubMed ID: 25504045

Title: Homozygous mutation of STXBP5L explains an autosomal recessive infantile-onset neurodegenerative disorder.

PubMed ID: 25504045

DOI: 10.1093/hmg/ddu614

Sequence Information:

  • Length: 1186
  • Mass: 131887
  • Checksum: 8CBDB5FAB4B777DA
  • Sequence:
    • MKKFNFRKVL DGLTASSPGS GSSSGSNSGG GAGSGSVHPA GTAGVLREEI QETLTSEYFQ 
ICKTVRHGFP HQPTALAFDP VQKILAIGTR TGAIRILGRP GVDCYCQHES GAAVLQLQFL 
INEGALVSAS SDDTLHLWNL RQKRPAILHS LKFNRERITY CHLPFQSKWL YVGTERGNTH 
IVNIESFILS GYVIMWNKAI ELSTKTHPGP VVHLSDSPRD EGKLLIGYEN GTVVFWDLKS 
KRAELRVYYD EAIHSIDWHH EGKQFMCSHS DGSLTLWNLK SPSRPFQTTI PHGKSQREGR 
KSESCKPILK VEYKTCKNSE PFIIFSGGLS YDKACRRPSL TIMHGKAITV LEMDHPIVEF 
LTLCETPYPN EFQEPYAVVV LLEKDLIVVD LTQSNFPIFE NPYPMDIHES PVTCTAYFAD 
CPPDLILVLY SIGVKHKKQG YSNKEWPISG GAWNLGAQTY PEIIITGHAD GSIKFWDASA 
ITLQMLYKLK TSKVFEKQKV GEGKQTCEIV EEDPFAIQMI YWCPESRIFC VSGVSAYVII 
YKFSRHEITT EIVSLEVRLQ YDVEDIITPE PETSPPFPDL SAQLPSSRSL SGSTNTVASE 
GVTKDSIPCL NVKTRPVRMP PGYQAELVIQ LVWVDGEPPQ QITSLAVSSA YGIVAFGNCN 
GLAVVDFIQK TVLLSMGTID LYRSSDLYQR QPRSPRKNKQ FIADNFCMRG LSNFYPDLTK 
RIRTSYQSLT ELNDSPVPLE LERCKSPTSD HVNGHCTSPT SQSCSSGKRL SSADVSKVNR 
WGPGRPPFRK AQSAACMEIS LPVTTEENRE NSYNRSRSSS ISSIDKDSKE AITALYFMDS 
FARKNDSTIS PCLFVGTSLG MVLIISLNLP LADEQRFTEP VMVLPSGTFL SLKGAVLTFS 
CMDRMGGLMQ PPYEVWRDPN NIDENEKSWR RKVVMNSSSA SQEIGDHQYT IICSEKQAKV 
FSLPSQTCLY VHNITETSFI LQANVVVMCS SACLACFCAN GHIMIMSLPS LRPMLDVNYL 
PLTDMRIART FCFTNEGQAL YLVSPTEIQR LTYSQEMCDN LQDMLGDLFT PIETPEAQNR 
GFLKGLFGGS GQTFDREELF GEASAGKASR SLAQHIPGPG SIEGMKGAAG GVMGELTRAR 
IALDERGQRL GELEEKTAGM MTSAEAFSKH AHELMLKYKD KKWYQF

Genular Protein ID: 1069551674

Symbol: B4DKF6_HUMAN

Name: N/A

UniProtKB Accession Codes:

B4DKF6

Database IDs:

ARBA 11 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 8 Gene3D 2 InterPro 8 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PROSITE-ProRule 2 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SMART 1 SUPFAM 2

Sequence Information:

  • Length: 1162
  • Mass: 128996
  • Checksum: E5DE270C858C9FFB
  • Sequence:
    • MKKFNFRKVL DGLTASSPGS GSSSGSNSGG GAGSGSVHPA GTAGVLREEI QETLTSEYFQ 
ICKTVRHGFP HQPTALAFDP VQKILAIGTR TGAIRILGRP GVDCYCQHES GAAVLQLQFL 
INEGALVSAS SDDTLHLWNL RQKRPAILHS LKFNRERITY CHLPFQSKWL YVGTERGNTH 
IVNIESFILS GYVIMWNKAI ELSTKTHPGP VVHLSDSPRD EGKLLIGYEN GTVVFWDLKS 
KRAELRVYYD EAIHSIDWHH EGKQFMCSHS DGSLTLWNLK SPSRPFQTTI PHGKSQREGR 
KSESCKPILK VEYKTCKNSE PFIIFSGGLS YDKACRRPSL TIMHGKAITV LEMDHPIVEF 
LTLCETPYPN EFQEPYAVVV LLEKDLIVVD LTQSNFPIFE NPYPMDIHES PVTCTAYFAD 
CPPDLILVLY SIGVKHKKQG YSNKEWPISG GAWNLGAQTY PEIIITGHAD GSIKFWYASA 
ITLQMLYKLK TSKVFEKQKV GEGKQTCEIV EEDPFAIQMI YWCPESRIFC VSGVSAYVII 
YKFSRHEITT EIVSLEVRLQ YDVEDIITPE PETSPPFPDL SAQLPSSRSL SGSTNTVASE 
GVTKDSIPCL NVKTRPVRMP PGYQAELVIQ LVWVDGEPPQ QITSLAVSSA YGIVAFGNCN 
GLAVVDFIQK TVLLSMGTID LYRSSDLYQR QPRSPRKNKQ FIAGLTELND SPVPLELERC 
KSPTSDHVNG HCTSPTSQSC SSGKRLSSAD VSKVNRWGPG RPPFRKAQSA ACMEISLPVT 
TEENRENSYN RSRSSSISSI DKDSKEAITA LYFMDSFARK NDSTISPCLF VGTSLGMVLI 
ISLNLPLADE QRFTEPVMVL PSGTFLSLKG AVLTFSCMDR MGGLMQPPYE VWRDPNNIDE 
NEKSWRRKVV MNSSSASQEI GDHQYTIICS EKQAKVFSLP SQTCLYVHNI TETSFILQAN 
VVVMCSSACL ACFCANGHIM IMSLPSLRPM LDVNYLPLTD MRIARTFCFT NEGQALYLVS 
PTEIQRLTYS QEMCDNLQDM LGDLFTPIET PEAQNRGFLK GLFGGSGQTF DREELFGEAS 
AGKASRSLAQ HIPGPGSIEG MKGAAGGVMG ELTRARIALD ERGQRLGELE EKTAGMMTSA 
EAFSKHAHEL MLKYKDKKWY QF

Genular Protein ID: 655494211

Symbol: E9PFI2_HUMAN

Name: N/A

UniProtKB Accession Codes:

E9PFI2

Database IDs:

ARBA 11 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 7 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 2 GeneTree 1 HGNC 1 InterPro 8 MANE-Select 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 4 PROSITE-ProRule 2 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 2 RefSeq 3 SAM 1 SMART 1 SMR 1 SUPFAM 2 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 16641997

Title: The DNA sequence, annotation and analysis of human chromosome 3.

PubMed ID: 16641997

DOI: 10.1038/nature04728

PubMed ID: 22814378

Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

PubMed ID: 22814378

DOI: 10.1073/pnas.1210303109

Sequence Information:

  • Length: 1162
  • Mass: 128948
  • Checksum: 3714B91621A67D1C
  • Sequence:
    • MKKFNFRKVL DGLTASSPGS GSSSGSNSGG GAGSGSVHPA GTAGVLREEI QETLTSEYFQ 
ICKTVRHGFP HQPTALAFDP VQKILAIGTR TGAIRILGRP GVDCYCQHES GAAVLQLQFL 
INEGALVSAS SDDTLHLWNL RQKRPAILHS LKFNRERITY CHLPFQSKWL YVGTERGNTH 
IVNIESFILS GYVIMWNKAI ELSTKTHPGP VVHLSDSPRD EGKLLIGYEN GTVVFWDLKS 
KRAELRVYYD EAIHSIDWHH EGKQFMCSHS DGSLTLWNLK SPSRPFQTTI PHGKSQREGR 
KSESCKPILK VEYKTCKNSE PFIIFSGGLS YDKACRRPSL TIMHGKAITV LEMDHPIVEF 
LTLCETPYPN EFQEPYAVVV LLEKDLIVVD LTQSNFPIFE NPYPMDIHES PVTCTAYFAD 
CPPDLILVLY SIGVKHKKQG YSNKEWPISG GAWNLGAQTY PEIIITGHAD GSIKFWDASA 
ITLQMLYKLK TSKVFEKQKV GEGKQTCEIV EEDPFAIQMI YWCPESRIFC VSGVSAYVII 
YKFSRHEITT EIVSLEVRLQ YDVEDIITPE PETSPPFPDL SAQLPSSRSL SGSTNTVASE 
GVTKDSIPCL NVKTRPVRMP PGYQAELVIQ LVWVDGEPPQ QITSLAVSSA YGIVAFGNCN 
GLAVVDFIQK TVLLSMGTID LYRSSDLYQR QPRSPRKNKQ FIAGLTELND SPVPLELERC 
KSPTSDHVNG HCTSPTSQSC SSGKRLSSAD VSKVNRWGPG RPPFRKAQSA ACMEISLPVT 
TEENRENSYN RSRSSSISSI DKDSKEAITA LYFMDSFARK NDSTISPCLF VGTSLGMVLI 
ISLNLPLADE QRFTEPVMVL PSGTFLSLKG AVLTFSCMDR MGGLMQPPYE VWRDPNNIDE 
NEKSWRRKVV MNSSSASQEI GDHQYTIICS EKQAKVFSLP SQTCLYVHNI TETSFILQAN 
VVVMCSSACL ACFCANGHIM IMSLPSLRPM LDVNYLPLTD MRIARTFCFT NEGQALYLVS 
PTEIQRLTYS QEMCDNLQDM LGDLFTPIET PEAQNRGFLK GLFGGSGQTF DREELFGEAS 
AGKASRSLAQ HIPGPGSIEG MKGAAGGVMG ELTRARIALD ERGQRLGELE EKTAGMMTSA 
EAFSKHAHEL MLKYKDKKWY QF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.