FGF5 | ENSG00000138675 | NCBI 2250

Details for: FGF5

Gene ID: 2250

Symbol: FGF5

Ensembl ID: ENSG00000138675

Description: fibroblast growth factor 5

Associated with

Activated point mutants of fgfr2
(R-HSA-2033519)
Constitutive signaling by aberrant pi3k in cancer
(R-HSA-2219530)
Disease
(R-HSA-1643685)
Diseases of signal transduction by growth factor receptors and second messengers
(R-HSA-5663202)
Downstream signaling of activated fgfr1
(R-HSA-5654687)
Downstream signaling of activated fgfr2
(R-HSA-5654696)
Downstream signaling of activated fgfr3
(R-HSA-5654708)
Fgfr1 ligand binding and activation
(R-HSA-190242)
Fgfr1 mutant receptor activation
(R-HSA-1839124)
Fgfr1c ligand binding and activation
(R-HSA-190373)
Fgfr2 ligand binding and activation
(R-HSA-190241)
Fgfr2 mutant receptor activation
(R-HSA-1839126)
Fgfr2c ligand binding and activation
(R-HSA-190375)
Fgfr3 ligand binding and activation
(R-HSA-190239)
Fgfr3 mutant receptor activation
(R-HSA-2033514)
Fgfr3c ligand binding and activation
(R-HSA-190372)
Fgfrl1 modulation of fgfr1 signaling
(R-HSA-5658623)
Frs-mediated fgfr1 signaling
(R-HSA-5654693)
Frs-mediated fgfr2 signaling
(R-HSA-5654700)
Frs-mediated fgfr3 signaling
(R-HSA-5654706)
Igf1r signaling cascade
(R-HSA-2428924)
Insulin receptor signalling cascade
(R-HSA-74751)
Intracellular signaling by second messengers
(R-HSA-9006925)
Irs-mediated signalling
(R-HSA-112399)
Irs-related events triggered by igf1r
(R-HSA-2428928)
Mapk1/mapk3 signaling
(R-HSA-5684996)
Mapk family signaling cascades
(R-HSA-5683057)
Negative regulation of fgfr1 signaling
(R-HSA-5654726)
Negative regulation of fgfr2 signaling
(R-HSA-5654727)
Negative regulation of fgfr3 signaling
(R-HSA-5654732)
Negative regulation of the pi3k/akt network
(R-HSA-199418)
Phospholipase c-mediated cascade: fgfr1
(R-HSA-5654219)
Phospholipase c-mediated cascade; fgfr2
(R-HSA-5654221)
Phospholipase c-mediated cascade; fgfr3
(R-HSA-5654227)
Pi-3k cascade:fgfr1
(R-HSA-5654689)
Pi-3k cascade:fgfr2
(R-HSA-5654695)
Pi-3k cascade:fgfr3
(R-HSA-5654710)
Pi3k/akt signaling in cancer
(R-HSA-2219528)
Pi3k cascade
(R-HSA-109704)
Pi5p, pp2a and ier3 regulate pi3k/akt signaling
(R-HSA-6811558)
Pip3 activates akt signaling
(R-HSA-1257604)
Raf/map kinase cascade
(R-HSA-5673001)
Shc-mediated cascade:fgfr1
(R-HSA-5654688)
Shc-mediated cascade:fgfr2
(R-HSA-5654699)
Shc-mediated cascade:fgfr3
(R-HSA-5654704)
Signaling by activated point mutants of fgfr1
(R-HSA-1839122)
Signaling by activated point mutants of fgfr3
(R-HSA-1839130)
Signaling by fgfr
(R-HSA-190236)
Signaling by fgfr1
(R-HSA-5654736)
Signaling by fgfr1 in disease
(R-HSA-5655302)
Signaling by fgfr2
(R-HSA-5654738)
Signaling by fgfr2 in disease
(R-HSA-5655253)
Signaling by fgfr3
(R-HSA-5654741)
Signaling by fgfr3 in disease
(R-HSA-5655332)
Signaling by fgfr in disease
(R-HSA-1226099)
Signaling by insulin receptor
(R-HSA-74752)
Signaling by receptor tyrosine kinases
(R-HSA-9006934)
Signaling by type 1 insulin-like growth factor 1 receptor (igf1r)
(R-HSA-2404192)
Signal transduction
(R-HSA-162582)
Cell-cell signaling
(GO:0007267)
Cytoplasm
(GO:0005737)
Extracellular region
(GO:0005576)
Extracellular space
(GO:0005615)
Fibroblast growth factor receptor binding
(GO:0005104)
Fibroblast growth factor receptor signaling pathway
(GO:0008543)
Glial cell differentiation
(GO:0010001)
Growth factor activity
(GO:0008083)
Nervous system development
(GO:0007399)
Neurogenesis
(GO:0022008)
Positive regulation of cell division
(GO:0051781)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of mapk cascade
(GO:0043410)
Regulation of cell migration
(GO:0030334)
Signal transduction involved in regulation of gene expression
(GO:0023019)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

Cell Name: colon endothelial cell (CL1001572)
Fold Change: 4.1535
Cell Significance Index: 3.1700
Cell Name: granule cell (CL0000120)
Fold Change: 3.6927
Cell Significance Index: 42.0400
Cell Name: stellate neuron (CL0000122)
Fold Change: 3.3176
Cell Significance Index: 37.6800
Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 2.8961
Cell Significance Index: 49.6300
Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
Fold Change: 0.8855
Cell Significance Index: 9.8300
Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.6998
Cell Significance Index: 19.9700
Cell Name: cytotoxic T cell (CL0000910)
Fold Change: 0.4021
Cell Significance Index: 5.8600
Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.2815
Cell Significance Index: 56.4700
Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.1443
Cell Significance Index: 3.1600
Cell Name: retinal blood vessel endothelial cell (CL0002585)
Fold Change: 0.0526
Cell Significance Index: 0.6800
Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
Fold Change: 0.0418
Cell Significance Index: 0.4300
Cell Name: keratocyte (CL0002363)
Fold Change: 0.0403
Cell Significance Index: 0.6400
Cell Name: suprabasal keratinocyte (CL4033013)
Fold Change: 0.0336
Cell Significance Index: 0.5400
Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: 0.0208
Cell Significance Index: 0.2900
Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.0081
Cell Significance Index: 5.6100
Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.0061
Cell Significance Index: 2.2100
Cell Name: keratinocyte (CL0000312)
Fold Change: 0.0020
Cell Significance Index: 0.0500
Cell Name: abnormal cell (CL0001061)
Fold Change: 0.0017
Cell Significance Index: 0.1700
Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0004
Cell Significance Index: -0.0200
Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0014
Cell Significance Index: -2.6400
Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0019
Cell Significance Index: -3.4200
Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0022
Cell Significance Index: -3.4200
Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0026
Cell Significance Index: -3.4900
Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0028
Cell Significance Index: -2.1000
Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0041
Cell Significance Index: -2.5800
Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0051
Cell Significance Index: -1.4600
Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0051
Cell Significance Index: -2.8600
Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0053
Cell Significance Index: -3.3000
Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0057
Cell Significance Index: -3.1100
Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0058
Cell Significance Index: -2.6400
Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0066
Cell Significance Index: -0.5100
Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0088
Cell Significance Index: -0.5900
Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0091
Cell Significance Index: -1.8000
Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0130
Cell Significance Index: -2.3400
Cell Name: odontoblast (CL0000060)
Fold Change: -0.0130
Cell Significance Index: -1.6700
Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0131
Cell Significance Index: -2.7700
Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.0135
Cell Significance Index: -0.1800
Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0152
Cell Significance Index: -2.5900
Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0155
Cell Significance Index: -2.2600
Cell Name: neuron (CL0000540)
Fold Change: -0.0158
Cell Significance Index: -0.1500
Cell Name: lactocyte (CL0002325)
Fold Change: -0.0201
Cell Significance Index: -2.6000
Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0205
Cell Significance Index: -2.8200
Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0209
Cell Significance Index: -2.5800
Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0223
Cell Significance Index: -0.7100
Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0243
Cell Significance Index: -2.7900
Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0271
Cell Significance Index: -0.9500
Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.0328
Cell Significance Index: -2.6000
Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0334
Cell Significance Index: -0.9100
Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0352
Cell Significance Index: -2.6200
Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.0354
Cell Significance Index: -0.9100
Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0370
Cell Significance Index: -0.5300
Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0393
Cell Significance Index: -1.7800
Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0439
Cell Significance Index: -2.8300
Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0454
Cell Significance Index: -2.7900
Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -0.0465
Cell Significance Index: -0.6200
Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0506
Cell Significance Index: -2.8400
Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.0512
Cell Significance Index: -2.6700
Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.0542
Cell Significance Index: -0.5900
Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0561
Cell Significance Index: -2.6400
Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0583
Cell Significance Index: -3.0600
Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.0613
Cell Significance Index: -0.8900
Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0621
Cell Significance Index: -2.7500
Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0623
Cell Significance Index: -2.0400
Cell Name: neural cell (CL0002319)
Fold Change: -0.0634
Cell Significance Index: -0.7400
Cell Name: hematopoietic stem cell (CL0000037)
Fold Change: -0.0649
Cell Significance Index: -1.1100
Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0721
Cell Significance Index: -2.7300
Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0753
Cell Significance Index: -3.5100
Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -0.0768
Cell Significance Index: -2.6700
Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.0798
Cell Significance Index: -2.3500
Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
Fold Change: -0.0830
Cell Significance Index: -0.9100
Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.0853
Cell Significance Index: -1.2600
Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.0867
Cell Significance Index: -2.4900
Cell Name: erythrocyte (CL0000232)
Fold Change: -0.0883
Cell Significance Index: -2.2500
Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0891
Cell Significance Index: -3.2700
Cell Name: neuronal brush cell (CL0000555)
Fold Change: -0.0921
Cell Significance Index: -1.0000
Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.0968
Cell Significance Index: -2.6000
Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0968
Cell Significance Index: -2.7900
Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0985
Cell Significance Index: -2.7500
Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0996
Cell Significance Index: -2.4900
Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.1001
Cell Significance Index: -2.1300
Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1038
Cell Significance Index: -2.7300
Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1051
Cell Significance Index: -2.8100
Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1061
Cell Significance Index: -2.1300
Cell Name: epithelial cell of proximal tubule (CL0002306)
Fold Change: -0.1086
Cell Significance Index: -0.8300
Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.1116
Cell Significance Index: -2.2700
Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: -0.1117
Cell Significance Index: -1.5500
Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: -0.1125
Cell Significance Index: -2.0800
Cell Name: interneuron (CL0000099)
Fold Change: -0.1147
Cell Significance Index: -1.3400
Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.1174
Cell Significance Index: -2.5100
Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.1195
Cell Significance Index: -2.9000
Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.1195
Cell Significance Index: -1.6300
Cell Name: cortical interneuron (CL0008031)
Fold Change: -0.1197
Cell Significance Index: -2.8700
Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.1198
Cell Significance Index: -2.5000
Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.1206
Cell Significance Index: -2.6100
Cell Name: L6 corticothalamic-projecting glutamatergic cortical neuron (CL4023042)
Fold Change: -0.1215
Cell Significance Index: -1.3400
Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.1242
Cell Significance Index: -3.0300
Cell Name: hepatic stellate cell (CL0000632)
Fold Change: -0.1260
Cell Significance Index: -1.3000
Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.1274
Cell Significance Index: -2.7600
Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.1276
Cell Significance Index: -6.4500
Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.1305
Cell Significance Index: -2.5800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

**Key Characteristics:** 1. **Structure:** FGF5 is a small, secreted protein with a single chain of 154 amino acids. 2. **Receptors:** FGF5 binds to FGFRs, specifically FGFR1, FGFR2, and FGFR3, which are tyrosine kinase receptors that undergo autophosphorylation upon binding to FGF5. 3. **Signaling pathways:** FGF5 activates several signaling pathways, including the MAPK/ERK, PI3K/AKT, and JAK/STAT pathways, which regulate various cellular processes, including cell proliferation, differentiation, and survival. 4. **Expression:** FGF5 is expressed in various tissues, including kidney proximal convoluted tubule epithelial cells, stellate neurons, blood vessel endothelial cells, granule cells, macroglial cells, goblet cells, and L5 extratelencephalic projecting glutamatergic cortical neurons. **Pathways and Functions:** 1. **Cell differentiation:** FGF5 regulates cell differentiation by activating the MAPK/ERK pathway, which promotes the expression of specific genes involved in cell fate determination. 2. **Cell migration:** FGF5 promotes cell migration by activating the PI3K/AKT pathway, which regulates the cytoskeleton and cell adhesion molecules. 3. **Angiogenesis:** FGF5 is involved in angiogenesis, the process of new blood vessel formation, by activating the PI3K/AKT pathway and promoting the expression of vascular endothelial growth factor (VEGF). 4. **Tissue development:** FGF5 plays a crucial role in tissue development, including embryonic development, organogenesis, and tissue homeostasis. 5. **Cancer:** FGF5 is overexpressed in various types of cancer, including breast, lung, and colon cancer, and its dysregulation contributes to tumorigenesis, metastasis, and resistance to therapy. **Clinical Significance:** 1. **Cancer therapy:** FGF5 is a potential target for cancer therapy, as its dysregulation contributes to tumorigenesis and metastasis. 2. **Regenerative medicine:** FGF5 is involved in tissue repair and regeneration, and its dysregulation contributes to various diseases, including cardiovascular diseases and developmental disorders. 3. **Neurological disorders:** FGF5 is involved in neurological development and function, and its dysregulation contributes to various neurological disorders, including autism spectrum disorder and schizophrenia. 4. **Diabetes:** FGF5 is involved in glucose homeostasis, and its dysregulation contributes to insulin resistance and type 2 diabetes. In conclusion, FGF5 is a multifaceted gene involved in various biological processes, including cell proliferation, differentiation, migration, and survival. Its dysregulation contributes to various diseases, including cancer, developmental disorders, cardiovascular diseases, and neurological disorders. Further research is needed to fully understand the role of FGF5 in human disease and to develop effective therapeutic strategies to modulate its activity.

Disclaimer: This summary is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.

Fibroblast growth factor 5
Q8NBG6_HUMAN

Genular Protein ID: 2403595967

Symbol: FGF5_HUMAN

Name: Fibroblast growth factor 5

UniProtKB Accession Codes:

P12034 B2R554 O75846 Q3Y8M3 Q8NF90

Database IDs:

Citations:

PubMed ID: 1700424

Title: Expression of the murine fibroblast growth factor 5 gene in the adult central nervous system.

PubMed ID: 1700424

DOI: 10.1073/pnas.87.20.8022

PubMed ID: 3211147

Title: The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors.

PubMed ID: 3211147

DOI: 10.1128/mcb.8.8.3487-3495.1988

PubMed ID: 10823842

Title: Differential display identification of 40 genes with altered expression in activated human smooth muscle cells. Local expression in atherosclerotic lesions of smags, smooth muscle activation-specific genes.

PubMed ID: 10823842

DOI: 10.1074/jbc.m910099199

PubMed ID: 11454700

Title: Identification of fibroblast growth factor-5 as an overexpressed antigen in multiple human adenocarcinomas.

PubMed ID: 11454700

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 8663044

Title: Receptor specificity of the fibroblast growth factor family.

PubMed ID: 8663044

DOI: 10.1074/jbc.271.25.15292

PubMed ID: 20094046

Title: Fibroblast growth factor signalling: from development to cancer.

PubMed ID: 20094046

DOI: 10.1038/nrc2780

PubMed ID: 24989505

Title: FGF5 is a crucial regulator of hair length in humans.

PubMed ID: 24989505

DOI: 10.1073/pnas.1402862111

Sequence Information:

Length: 268
Mass: 29551
Checksum: 28B7268B26781BCF
Sequence:

MSLSFLLLLF FSHLILSAWA HGEKRLAPKG QPGPAATDRN PRGSSSRQSS SSAMSSSSAS 
SSPAASLGSQ GSGLEQSSFQ WSPSGRRTGS LYCRVGIGFH LQIYPDGKVN GSHEANMLSV 
LEIFAVSQGI VGIRGVFSNK FLAMSKKGKL HASAKFTDDC KFRERFQENS YNTYASAIHR 
TEKTGREWYV ALNKRGKAKR GCSPRVKPQH ISTHFLPRFK QSEQPELSFT VTVPEKKKPP 
SPIKPKIPLS APRKNTNSVK YRLKFRFG

Genular Protein ID: 3920359667

Symbol: Q8NBG6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8NBG6

Database IDs:

Citations:

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

Length: 125
Mass: 14536
Checksum: EDBB5B1C85B6BBCE
Sequence:

MSKKGKLHAS AKFTDDCKFR ERFQENSYNT YASAIHRTEK TGREWYVALN KRGKAKRGCS 
PRVKPQHIST HFLPRFKQSE QPELSFTVTV PEKKKPPSPI KPKIPLSAPR KNTNSVKYRL 
KFRFG

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: FGF5

Associated with

Cells (max top 100)

Other Information

Expression of the murine fibroblast growth factor 5 gene in the adult central nervous system. PubMed ID: 1700424

The human FGF-5 oncogene encodes a novel protein related to fibroblast growth factors. PubMed ID: 3211147

Differential display identification of 40 genes with altered expression in activated human smooth muscle cells. Local expression in atherosclerotic lesions of smags, smooth muscle activation-specific genes. PubMed ID: 10823842

Identification of fibroblast growth factor-5 as an overexpressed antigen in multiple human adenocarcinomas. PubMed ID: 11454700

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Receptor specificity of the fibroblast growth factor family. PubMed ID: 8663044

Fibroblast growth factor signalling: from development to cancer. PubMed ID: 20094046

FGF5 is a crucial regulator of hair length in humans. PubMed ID: 24989505

Complete sequencing and characterization of 21,243 full-length human cDNAs. PubMed ID: 14702039

Database document:

PubMed ID: 1700424

PubMed ID: 3211147

PubMed ID: 10823842

PubMed ID: 11454700

PubMed ID: 14702039

PubMed ID: 15489334

PubMed ID: 8663044

PubMed ID: 20094046

PubMed ID: 24989505

PubMed ID: 14702039