Details for: GHR

Gene ID: 2690

Symbol: GHR

Ensembl ID: ENSG00000112964

Description: growth hormone receptor

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 5.42
    Marker Score: 16059.5
  • Cell Name: subcutaneous fat cell (CL0002521)
    Fold Change: 4.52
    Marker Score: 1654
  • Cell Name: fat cell (CL0000136)
    Fold Change: 3.83
    Marker Score: 2138
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 3.72
    Marker Score: 9326
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: 3.28
    Marker Score: 2159
  • Cell Name: kidney interstitial fibroblast (CL1000692)
    Fold Change: 2.75
    Marker Score: 5287
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 2.62
    Marker Score: 1177
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.24
    Marker Score: 9272
  • Cell Name: alveolar type 2 fibroblast cell (CL4028006)
    Fold Change: 2.18
    Marker Score: 1211
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.12
    Marker Score: 19972
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 2.1
    Marker Score: 2417
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 2.02
    Marker Score: 641
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 2.01
    Marker Score: 6572
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 1.96
    Marker Score: 34756
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: 1.95
    Marker Score: 1134
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 1.94
    Marker Score: 43414
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 1.93
    Marker Score: 71209
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.89
    Marker Score: 17958
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 1.89
    Marker Score: 10138
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 1.86
    Marker Score: 5347
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.78
    Marker Score: 109261
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 1.73
    Marker Score: 11132
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 1.66
    Marker Score: 7157
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.64
    Marker Score: 809
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.57
    Marker Score: 13478
  • Cell Name: renal principal cell (CL0005009)
    Fold Change: 1.56
    Marker Score: 1203
  • Cell Name: renal interstitial pericyte (CL1001318)
    Fold Change: 1.56
    Marker Score: 1485
  • Cell Name: regular atrial cardiac myocyte (CL0002129)
    Fold Change: 1.51
    Marker Score: 5359.5
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.47
    Marker Score: 3470
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.46
    Marker Score: 167933
  • Cell Name: basal epithelial cell of prostatic duct (CL0002236)
    Fold Change: 1.45
    Marker Score: 1290
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 1.41
    Marker Score: 28120
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 1.41
    Marker Score: 47713
  • Cell Name: skin fibroblast (CL0002620)
    Fold Change: 1.4
    Marker Score: 364
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 1.4
    Marker Score: 1726
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 1.38
    Marker Score: 604
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.38
    Marker Score: 5612.5
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.36
    Marker Score: 861
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 1.35
    Marker Score: 4787
  • Cell Name: adipocyte of epicardial fat of left ventricle (CL1000311)
    Fold Change: 1.34
    Marker Score: 353.5
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 1.33
    Marker Score: 1422
  • Cell Name: podocyte (CL0000653)
    Fold Change: 1.32
    Marker Score: 488
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.3
    Marker Score: 2184
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 1.28
    Marker Score: 2815
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 1.28
    Marker Score: 20005
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.27
    Marker Score: 2591
  • Cell Name: contractile cell (CL0000183)
    Fold Change: 1.25
    Marker Score: 676
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 1.25
    Marker Score: 906
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 1.19
    Marker Score: 1351
  • Cell Name: fast muscle cell (CL0000190)
    Fold Change: 1.17
    Marker Score: 354
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.16
    Marker Score: 1791
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 1.16
    Marker Score: 365
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 1.14
    Marker Score: 4782
  • Cell Name: cardiac neuron (CL0010022)
    Fold Change: 1.11
    Marker Score: 1379
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 1.04
    Marker Score: 240
  • Cell Name: parietal epithelial cell (CL1000452)
    Fold Change: 1.02
    Marker Score: 369
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 1.02
    Marker Score: 383
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1
    Marker Score: 603
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71771
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 47995
  • Cell Name: mesangial cell (CL0000650)
    Fold Change: 0.99
    Marker Score: 1197
  • Cell Name: osteoblast (CL0000062)
    Fold Change: 0.99
    Marker Score: 532
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 0.98
    Marker Score: 853
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30405
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.97
    Marker Score: 502
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.97
    Marker Score: 457
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2411
  • Cell Name: preosteoblast (CL0007010)
    Fold Change: 0.93
    Marker Score: 264
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 0.93
    Marker Score: 707
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.93
    Marker Score: 5288
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.92
    Marker Score: 370
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: 0.92
    Marker Score: 5506
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2734
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.9
    Marker Score: 323
  • Cell Name: kidney capillary endothelial cell (CL1000892)
    Fold Change: 0.9
    Marker Score: 281
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.89
    Marker Score: 9149
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: 0.88
    Marker Score: 725
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5295
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 0.85
    Marker Score: 1203
  • Cell Name: Leydig cell (CL0000178)
    Fold Change: 0.84
    Marker Score: 904
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.83
    Marker Score: 634.5
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.82
    Marker Score: 563
  • Cell Name: interneuron (CL0000099)
    Fold Change: 0.82
    Marker Score: 374
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 0.79
    Marker Score: 29964
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.78
    Marker Score: 1266
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 0.77
    Marker Score: 1811
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.77
    Marker Score: 367
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.76
    Marker Score: 693
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 393
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.75
    Marker Score: 3152
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 0.74
    Marker Score: 238
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 0.73
    Marker Score: 353
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: 0.72
    Marker Score: 178
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.71
    Marker Score: 415
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.69
    Marker Score: 178
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.69
    Marker Score: 223
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.68
    Marker Score: 256
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: 0.68
    Marker Score: 173
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.67
    Marker Score: 393
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 0.66
    Marker Score: 2225

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Other Information

**Key characteristics:** * The GHR gene is located on chromosome 17q21.2. * It is a single gene with a length of approximately 28 exons and 21 intronic regions. * The protein product of the GHR gene is a transmembrane protein with a molecular weight of approximately 130 kDa. * The GHR gene is highly expressed in many cell types, including off-bipolar cells, fat cells, skeletal muscle fibers, and epithelial cells. **Pathways and functions:** * The GHR gene is a key regulator of growth and differentiation in various tissues. * It is a ligand-gated receptor for growth hormone, a peptide hormone that is essential for growth and development in vertebrates. * Binding of growth hormone to the GHR triggers a cascade of intracellular events that ultimately lead to cell proliferation, differentiation, and survival. * The GHR also plays a role in metabolism, cell survival, and apoptosis (programmed cell death). **Clinical significance:** * Mutations in the GHR gene have been linked to several human diseases, including gigantism, obesity, and cancer. * The GHR gene is a target for therapeutic interventions in these diseases. * In cancer, the GHR is often overexpressed on tumor cells, leading to increased cell growth and metastasis. * Therefore, targeting the GHR signaling pathway is a promising strategy for cancer treatment. **Additional information:** * The GHR gene is also known as GHSR (growth hormone receptor) and GHRH (human growth hormone receptor). * The GHR is a highly conserved protein with sequences similar in mammals and humans. * The GHR is a member of the cytokine receptor superfamily, which also includes the EGFR (epidermal growth factor receptor) and the PDGF (platelet-derived growth factor receptor).

Genular Protein ID: 2708394047

Symbol: GHR_HUMAN

Name: Growth hormone receptor

UniProtKB Accession Codes:

P10912 Q9HCX2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 2 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 DisProt 1 DrugBank 5 DrugCentral 1 ELM 1 EMBL 11 EPD 1 Ensembl 7 EvolutionaryTrace 1 ExpressionAtlas 1 GO 48 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 6 KEGG 1 MANE-Select 1 MIM 6 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PDB 15 PDBsum 9 PIR 1 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 3 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 Reactome 2 RefSeq 11 SAM 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2825030

Title: Growth hormone receptor and serum binding protein: purification, cloning and expression.

PubMed ID: 2825030

DOI: 10.1038/330537a0

PubMed ID: 2813379

Title: Characterization of the human growth hormone receptor gene and demonstration of a partial gene deletion in two patients with Laron-type dwarfism.

PubMed ID: 2813379

DOI: 10.1073/pnas.86.20.8083

PubMed ID: 1569971

Title: Expression of a human growth hormone (hGH) receptor isoform is predicted by tissue-specific alternative splicing of exon 3 of the hGH receptor gene transcript.

PubMed ID: 1569971

DOI: 10.1210/mend.6.2.1569971

PubMed ID: 8855247

Title: Alternatively spliced forms in the cytoplasmic domain of the human growth hormone (GH) receptor regulate its ability to generate a soluble GH-binding protein.

PubMed ID: 8855247

DOI: 10.1073/pnas.93.20.10723

PubMed ID: 9360546

Title: A membrane-fixed, truncated isoform of the human growth hormone receptor.

PubMed ID: 9360546

DOI: 10.1210/jcem.82.11.4358

PubMed ID: 9058373

Title: A short isoform of the human growth hormone receptor functions as a dominant negative inhibitor of the full-length receptor and generates large amounts of binding protein.

PubMed ID: 9058373

DOI: 10.1210/mend.11.3.9901

PubMed ID: 8360189

Title: Functional characterization of the alternatively spliced, placental human growth hormone receptor.

PubMed ID: 8360189

DOI: 10.1016/s0021-9258(17)46730-5

PubMed ID: 10764769

Title: Species-specific alternative splice mimicry at the growth hormone receptor locus revealed by the lineage of retroelements during primate evolution.

PubMed ID: 10764769

DOI: 10.1074/jbc.m001615200

PubMed ID: 2406245

Title: The human growth hormone receptor. Secretion from Escherichia coli and disulfide bonding pattern of the extracellular binding domain.

PubMed ID: 2406245

DOI: 10.1016/s0021-9258(19)39741-8

PubMed ID: 11785980

Title: Identification of a region critical for proteolysis of the human growth hormone receptor.

PubMed ID: 11785980

DOI: 10.1006/bbrc.2001.6261

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 1549776

Title: Human growth hormone and extracellular domain of its receptor: crystal structure of the complex.

PubMed ID: 1549776

DOI: 10.1126/science.1549776

PubMed ID: 8943276

Title: Crystal structure of an antagonist mutant of human growth hormone, G120R, in complex with its receptor at 2.9-A resolution.

PubMed ID: 8943276

DOI: 10.1074/jbc.271.50.32197

PubMed ID: 2779634

Title: Laron dwarfism and mutations of the growth hormone-receptor gene.

PubMed ID: 2779634

DOI: 10.1056/nejm198910123211501

PubMed ID: 8421103

Title: Amino acid substitutions in the intracellular part of the growth hormone receptor in a patient with the Laron syndrome.

PubMed ID: 8421103

DOI: 10.1210/jcem.76.1.8421103

PubMed ID: 8504296

Title: Spectrum of growth hormone receptor mutations and associated haplotypes in Laron syndrome.

PubMed ID: 8504296

DOI: 10.1093/hmg/2.4.355

PubMed ID: 8450064

Title: Lack of hormone binding in COS-7 cells expressing a mutated growth hormone receptor found in Laron dwarfism.

PubMed ID: 8450064

DOI: 10.1172/jci116304

PubMed ID: 8137822

Title: A single amino acid substitution in the exoplasmic domain of the human growth hormone (GH) receptor confers familial GH resistance (Laron syndrome) with positive GH-binding activity by abolishing receptor homodimerization.

PubMed ID: 8137822

DOI: 10.1002/j.1460-2075.1994.tb06392.x

PubMed ID: 7565946

Title: Mutations of the growth hormone receptor in children with idiopathic short stature.

PubMed ID: 7565946

DOI: 10.1056/nejm199510263331701

PubMed ID: 9024232

Title: Nine novel growth hormone receptor gene mutations in patients with Laron syndrome.

PubMed ID: 9024232

DOI: 10.1210/jcem.82.2.3725

PubMed ID: 9661642

Title: A novel mutation affecting the interdomain link region of the growth hormone receptor in a Vietnamese girl, and response to long-term treatment with recombinant human insulin-like growth factor-I and luteinizing hormone-releasing hormone analogue.

PubMed ID: 9661642

DOI: 10.1210/jcem.83.7.4954

PubMed ID: 9814495

Title: Growth hormone receptor mutations in children with idiopathic short stature.

PubMed ID: 9814495

DOI: 10.1210/jcem.83.11.5238

PubMed ID: 9851797

Title: Four contiguous amino acid substitutions, identified in patients with Laron syndrome, differently affect the binding affinity and intracellular trafficking of the growth hormone receptor.

PubMed ID: 9851797

DOI: 10.1210/jcem.83.12.5357

PubMed ID: 10391209

Title: Characterization of single-nucleotide polymorphisms in coding regions of human genes.

PubMed ID: 10391209

DOI: 10.1038/10290

PubMed ID: 10870033

Title: Characterisation of novel missense mutations in the GH receptor gene causing severe growth retardation.

PubMed ID: 10870033

DOI: 10.1530/eje.0.1430071

PubMed ID: 12910492

Title: Growth hormone receptor variant (L526I) modifies plasma HDL cholesterol phenotype in familial hypercholesterolemia: intra-familial association study in an eight-generation hyperlipidemic kindred.

PubMed ID: 12910492

DOI: 10.1002/ajmg.a.20172

PubMed ID: 14678285

Title: The first homozygous mutation (S226I) in the highly-conserved WSXWS-like motif of the GH receptor causing Laron syndrome: suppression of GH secretion by GnRH analogue therapy not restored by dihydrotestosterone administration.

PubMed ID: 14678285

DOI: 10.1111/j.1365-2265.2004.01930.x

Sequence Information:

  • Length: 638
  • Mass: 71500
  • Checksum: EAF77EADE4787822
  • Sequence:
    • MDLWQLLLTL ALAGSSDAFS GSEATAAILS RAPWSLQSVN PGLKTNSSKE PKFTKCRSPE 
RETFSCHWTD EVHHGTKNLG PIQLFYTRRN TQEWTQEWKE CPDYVSAGEN SCYFNSSFTS 
IWIPYCIKLT SNGGTVDEKC FSVDEIVQPD PPIALNWTLL NVSLTGIHAD IQVRWEAPRN 
ADIQKGWMVL EYELQYKEVN ETKWKMMDPI LTTSVPVYSL KVDKEYEVRV RSKQRNSGNY 
GEFSEVLYVT LPQMSQFTCE EDFYFPWLLI IIFGIFGLTV MLFVFLFSKQ QRIKMLILPP 
VPVPKIKGID PDLLKEGKLE EVNTILAIHD SYKPEFHSDD SWVEFIELDI DEPDEKTEES 
DTDRLLSSDH EKSHSNLGVK DGDSGRTSCC EPDILETDFN ANDIHEGTSE VAQPQRLKGE 
ADLLCLDQKN QNNSPYHDAC PATQQPSVIQ AEKNKPQPLP TEGAESTHQA AHIQLSNPSS 
LSNIDFYAQV SDITPAGSVV LSPGQKNKAG MSQCDMHPEM VSLCQENFLM DNAYFCEADA 
KKCIPVAPHI KVESHIQPSL NQEDIYITTE SLTTAAGRPG TGEHVPGSEM PVPDYTSIHI 
VQSPQGLILN ATALPLPDKE FLSSCGYVST DQLNKIMP

Genular Protein ID: 3147290305

Symbol: A0A087X162_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087X162

Database IDs:

ARBA 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 Ensembl 2 ExpressionAtlas 1 GO 4 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 InterPro 5 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 2 Pfam 2 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 2 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

Sequence Information:

  • Length: 295
  • Mass: 34045
  • Checksum: 98B1DD31AAC8F6FD
  • Sequence:
    • MDLWQLLLTL ALAGSSDAFS GSEATAAILS RAPWSLQSVN PGLKTNSSKE PKFTKCRSPE 
RETFSCHWTD EVHHGTKNLG PIQLFYTRRN TQEWTQEWKE CPDYVSAGEN SCYFNSSFTS 
IWIPYCIKLT SNGGTVDEKC FSVDEIVQPD PPIALNWTLL NVSLTGIHAD IQVRWEAPRN 
ADIQKGWMVL EYELQYKEVN ETKWKMMDPI LTTSVPVYSL KVDKEYEVRV RSKQRNSGNY 
GEFSEVLYVT LPQMSQFTCE EDFYFPWLLI IIFGIFGLTV MLFVFLFSKQ QRKEN

Genular Protein ID: 3168471881

Symbol: A0A087X0H5_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087X0H5

Database IDs:

ARBA 9 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 Ensembl 2 ExpressionAtlas 1 GO 5 Gene3D 1 GeneTree 1 GenomeRNAi 1 HGNC 1 InterPro 6 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 3 PeptideAtlas 2 Pfam 3 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 3 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 15372022

Title: The DNA sequence and comparative analysis of human chromosome 5.

PubMed ID: 15372022

DOI: 10.1038/nature02919

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 645
  • Mass: 72243
  • Checksum: D757356B10C5D250
  • Sequence:
    • MNWGPTGMDL WQLLLTLALA GSSDAFSGSE ATAAILSRAP WSLQSVNPGL KTNSSKEPKF 
TKCRSPERET FSCHWTDEVH HGTKNLGPIQ LFYTRRNTQE WTQEWKECPD YVSAGENSCY 
FNSSFTSIWI PYCIKLTSNG GTVDEKCFSV DEIVQPDPPI ALNWTLLNVS LTGIHADIQV 
RWEAPRNADI QKGWMVLEYE LQYKEVNETK WKMMDPILTT SVPVYSLKVD KEYEVRVRSK 
QRNSGNYGEF SEVLYVTLPQ MSQFTCEEDF YFPWLLIIIF GIFGLTVMLF VFLFSKQQRI 
KMLILPPVPV PKIKGIDPDL LKEGKLEEVN TILAIHDSYK PEFHSDDSWV EFIELDIDEP 
DEKTEESDTD RLLSSDHEKS HSNLGVKDGD SGRTSCCEPD ILETDFNAND IHEGTSEVAQ 
PQRLKGEADL LCLDQKNQNN SPYHDACPAT QQPSVIQAEK NKPQPLPTEG AESTHQAAHI 
QLSNPSSLSN IDFYAQVSDI TPAGSVVLSP GQKNKAGMSQ CDMHPEMVSL CQENFLMDNA 
YFCEADAKKC IPVAPHIKVE SHIQPSLNQE DIYITTESLT TAAGRPGTGE HVPGSEMPVP 
DYTSIHIVQS PQGLILNATA LPLPDKEFLS SCGYVSTDQL NKIMP

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.