Details for: GRIA4

Gene ID: 2893

Symbol: GRIA4

Ensembl ID: ENSG00000152578

Description: glutamate ionotropic receptor AMPA type subunit 4

Associated with

  • Activation of ampa receptors
    (R-HSA-399710)
  • Activation of nmda receptors and postsynaptic events
    (R-HSA-442755)
  • Glutamate binding, activation of ampa receptors and synaptic plasticity
    (R-HSA-399721)
  • Neuronal system
    (R-HSA-112316)
  • Neurotransmitter receptors and postsynaptic signal transmission
    (R-HSA-112314)
  • Protein-protein interactions at synapses
    (R-HSA-6794362)
  • Synaptic adhesion-like molecules
    (R-HSA-8849932)
  • Trafficking of ampa receptors
    (R-HSA-399719)
  • Trafficking of glur2-containing ampa receptors
    (R-HSA-416993)
  • Transmission across chemical synapses
    (R-HSA-112315)
  • Unblocking of nmda receptors, glutamate binding and activation
    (R-HSA-438066)
  • Ampa glutamate receptor activity
    (GO:0004971)
  • Ampa glutamate receptor complex
    (GO:0032281)
  • Amyloid-beta binding
    (GO:0001540)
  • Dendritic spine
    (GO:0043197)
  • Endocytic vesicle membrane
    (GO:0030666)
  • Extracellular vesicle
    (GO:1903561)
  • Glutamate-gated receptor activity
    (GO:0004970)
  • Glutamate receptor signaling pathway
    (GO:0007215)
  • Ionotropic glutamate receptor signaling pathway
    (GO:0035235)
  • Ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential
    (GO:0099507)
  • Modulation of chemical synaptic transmission
    (GO:0050804)
  • Monoatomic ion transmembrane transport
    (GO:0034220)
  • Negative regulation of smooth muscle cell apoptotic process
    (GO:0034392)
  • Neuronal cell body
    (GO:0043025)
  • Plasma membrane
    (GO:0005886)
  • Postsynaptic density membrane
    (GO:0098839)
  • Regulation of postsynaptic membrane potential
    (GO:0060078)
  • Regulation of presynaptic membrane potential
    (GO:0099505)
  • Synaptic transmission, glutamatergic
    (GO:0035249)
  • Transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential
    (GO:1904315)

Cells (max top 100)

(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: granule cell (CL0000120)
    Fold Change: 8.78
    Marker Score: 66,163
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: 8.72
    Marker Score: 45,752
  • Cell Name: macroglial cell (CL0000126)
    Fold Change: 6.9
    Marker Score: 15,858
  • Cell Name: stellate neuron (CL0000122)
    Fold Change: 5.26
    Marker Score: 28,241
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: 3.87
    Marker Score: 17,887
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 3.73
    Marker Score: 4,656
  • Cell Name: brainstem motor neuron (CL2000047)
    Fold Change: 3.47
    Marker Score: 2,018
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: 3.43
    Marker Score: 8,212
  • Cell Name: A2 amacrine cell (CL0004219)
    Fold Change: 3.29
    Marker Score: 1,043
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 3.16
    Marker Score: 4,254
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: 2.85
    Marker Score: 42,607
  • Cell Name: ganglion interneuron (CL0000397)
    Fold Change: 2.82
    Marker Score: 855
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.71
    Marker Score: 1,042
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 2.66
    Marker Score: 778
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: 2.62
    Marker Score: 10,871
  • Cell Name: OFF retinal ganglion cell (CL4023033)
    Fold Change: 2.59
    Marker Score: 1,086
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 2.59
    Marker Score: 3,128
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 2.56
    Marker Score: 2,417
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.55
    Marker Score: 5,176
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 2.47
    Marker Score: 10,325
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 2.45
    Marker Score: 90,278
  • Cell Name: vip GABAergic cortical interneuron (CL4023016)
    Fold Change: 2.4
    Marker Score: 91,140
  • Cell Name: cerebellar granule cell precursor (CL0002362)
    Fold Change: 2.32
    Marker Score: 1,298
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: 2.22
    Marker Score: 6,322
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: 2.2
    Marker Score: 20,654
  • Cell Name: chromaffin cell (CL0000166)
    Fold Change: 2.11
    Marker Score: 2,967
  • Cell Name: oligodendrocyte precursor cell (CL0002453)
    Fold Change: 2.08
    Marker Score: 2,570
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: 2.04
    Marker Score: 40,670
  • Cell Name: caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 2.03
    Marker Score: 7,862
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 2.03
    Marker Score: 124,908
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 1.96
    Marker Score: 3,705
  • Cell Name: neuron (CL0000540)
    Fold Change: 1.92
    Marker Score: 7,818
  • Cell Name: ON retinal ganglion cell (CL4023032)
    Fold Change: 1.91
    Marker Score: 523
  • Cell Name: microglial cell (CL0000129)
    Fold Change: 1.91
    Marker Score: 3,477
  • Cell Name: sympathetic neuron (CL0011103)
    Fold Change: 1.9
    Marker Score: 629
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 1.86
    Marker Score: 15,948
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 1.85
    Marker Score: 19,058
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: 1.63
    Marker Score: 12,499
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 1.57
    Marker Score: 1,182
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: 1.54
    Marker Score: 1,480
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: 1.49
    Marker Score: 14,200
  • Cell Name: astrocyte of the cerebral cortex (CL0002605)
    Fold Change: 1.48
    Marker Score: 31,674
  • Cell Name: mural cell (CL0008034)
    Fold Change: 1.46
    Marker Score: 167,278
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 1.37
    Marker Score: 868
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: 1.36
    Marker Score: 2,771
  • Cell Name: double negative thymocyte (CL0002489)
    Fold Change: 1.36
    Marker Score: 1,874
  • Cell Name: Bergmann glial cell (CL0000644)
    Fold Change: 1.34
    Marker Score: 546
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: 1.33
    Marker Score: 1,536
  • Cell Name: epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 1.32
    Marker Score: 592
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: 1.32
    Marker Score: 880
  • Cell Name: mature astrocyte (CL0002627)
    Fold Change: 1.3
    Marker Score: 856
  • Cell Name: GABAergic neuron (CL0000617)
    Fold Change: 1.29
    Marker Score: 5,397
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 1.29
    Marker Score: 775
  • Cell Name: pyramidal neuron (CL0000598)
    Fold Change: 1.23
    Marker Score: 2,062
  • Cell Name: astrocyte (CL0000127)
    Fold Change: 1.22
    Marker Score: 1,053
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 1.19
    Marker Score: 1,833
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 1.17
    Marker Score: 614
  • Cell Name: renal beta-intercalated cell (CL0002201)
    Fold Change: 1.15
    Marker Score: 363
  • Cell Name: kidney proximal straight tubule epithelial cell (CL1000839)
    Fold Change: 1.07
    Marker Score: 2,516
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.06
    Marker Score: 720
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 1.03
    Marker Score: 616
  • Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
    Fold Change: 1
    Marker Score: 71,789
  • Cell Name: forebrain radial glial cell (CL0013000)
    Fold Change: 1
    Marker Score: 48,015
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.99
    Marker Score: 508
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.99
    Marker Score: 409
  • Cell Name: absorptive cell (CL0000212)
    Fold Change: 0.98
    Marker Score: 30,406
  • Cell Name: CNS interneuron (CL0000402)
    Fold Change: 0.98
    Marker Score: 471
  • Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
    Fold Change: 0.98
    Marker Score: 462
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 0.98
    Marker Score: 15,297
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.95
    Marker Score: 2,413
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.93
    Marker Score: 374
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: 0.92
    Marker Score: 5,255
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: 0.91
    Marker Score: 2,740
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.91
    Marker Score: 326
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: 0.9
    Marker Score: 1,465
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.87
    Marker Score: 5,285
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.87
    Marker Score: 664
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.87
    Marker Score: 3,631
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.79
    Marker Score: 256
  • Cell Name: brush cell (CL0002204)
    Fold Change: 0.77
    Marker Score: 701
  • Cell Name: Cajal-Retzius cell (CL0000695)
    Fold Change: 0.76
    Marker Score: 396
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.74
    Marker Score: 731
  • Cell Name: neuronal brush cell (CL0000555)
    Fold Change: 0.74
    Marker Score: 2,471
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.72
    Marker Score: 462
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.72
    Marker Score: 228
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: 0.72
    Marker Score: 546
  • Cell Name: enterocyte of colon (CL1000347)
    Fold Change: 0.71
    Marker Score: 1,092
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: 0.7
    Marker Score: 221
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.7
    Marker Score: 179
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 0.69
    Marker Score: 958
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 0.69
    Marker Score: 357
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.67
    Marker Score: 22,760
  • Cell Name: glial cell (CL0000125)
    Fold Change: 0.64
    Marker Score: 706
  • Cell Name: starburst amacrine cell (CL0004232)
    Fold Change: 0.64
    Marker Score: 181
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: 0.63
    Marker Score: 415
  • Cell Name: smooth muscle myoblast (CL0000514)
    Fold Change: 0.61
    Marker Score: 293
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.61
    Marker Score: 357
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: 0.61
    Marker Score: 6,185
  • Cell Name: intestinal enteroendocrine cell (CL1001516)
    Fold Change: 0.58
    Marker Score: 463
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: 0.57
    Marker Score: 921

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The GRIA4 gene is a member of the GluR subfamily of AMPA receptor subunits, which are composed of four subunits (GluR1-4). Each subunit has distinct characteristics, including the presence of a glutamate-binding site and an ion channel pore. The GRIA4 subunit is specifically involved in the modulation of synaptic transmission, particularly at excitatory synapses. Its expression is tightly regulated, with a dynamic trafficking between the cell surface and endocytic vesicles. This dynamic regulation is crucial for the fine-tuning of synaptic strength and plasticity. **Pathways and Functions** GRIA4 is involved in several key pathways, including: 1. **Activation of AMPA receptors**: GRIA4 subunits assemble with other subunits to form functional AMPA receptors, which are activated by glutamate binding. This activation leads to the opening of the ion channel pore, allowing the influx of positively charged ions (Na+, K+) and the subsequent depolarization of the postsynaptic neuron. 2. **Postsynaptic events**: GRIA4-mediated AMPA receptor activation is critical for the regulation of postsynaptic events, including excitatory synaptic transmission and synaptic plasticity. 3. **Synaptic plasticity**: GRIA4 is involved in the regulation of synaptic strength and plasticity, particularly in the context of long-term potentiation (LTP) and long-term depression (LTD). 4. **Neurotransmitter receptors and postsynaptic signal transmission**: GRIA4 is also involved in the regulation of neurotransmitter receptors and postsynaptic signal transmission, particularly in the context of excitatory neurotransmission. **Clinical Significance** Dysregulation of GRIA4 has been implicated in various neurological and psychiatric disorders, including: 1. **Neurodegenerative diseases**: Altered GRIA4 expression has been observed in neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis (ALS). 2. **Mental health disorders**: Abnormal GRIA4 expression has been linked to mental health disorders, including depression, anxiety, and schizophrenia. 3. **Neuropsychiatric disorders**: GRIA4 has been implicated in the pathophysiology of neuropsychiatric disorders, such as attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). In summary, the GRIA4 gene plays a critical role in the regulation of synaptic transmission and plasticity, and its dysregulation has been implicated in various neurological and psychiatric disorders. Further research is needed to fully elucidate the functional roles of GRIA4 and its potential therapeutic targets for the treatment of these disorders.

Genular Protein ID: 874135712

Symbol: GRIA4_HUMAN

Name: Glutamate receptor 4

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8589990

Title: Cloning, expression and pharmacological characterization of a human glutamate receptor: hGluR4.

PubMed ID: 8589990

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21172611

Title: Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins.

PubMed ID: 21172611

DOI: 10.1016/j.neuron.2010.11.026

PubMed ID: 29220673

Title: De Novo Variants in GRIA4 Lead to Intellectual Disability with or without Seizures and Gait Abnormalities.

PubMed ID: 29220673

DOI: 10.1016/j.ajhg.2017.11.004

Sequence Information:

  • Length: 902
  • Mass: 100871
  • Checksum: 7793AEF0AB829FC5
  • Sequence:
  • MRIISRQIVL LFSGFWGLAM GAFPSSVQIG GLFIRNTDQE YTAFRLAIFL HNTSPNASEA 
    PFNLVPHVDN IETANSFAVT NAFCSQYSRG VFAIFGLYDK RSVHTLTSFC SALHISLITP 
    SFPTEGESQF VLQLRPSLRG ALLSLLDHYE WNCFVFLYDT DRGYSILQAI MEKAGQNGWH 
    VSAICVENFN DVSYRQLLEE LDRRQEKKFV IDCEIERLQN ILEQIVSVGK HVKGYHYIIA 
    NLGFKDISLE RFIHGGANVT GFQLVDFNTP MVIKLMDRWK KLDQREYPGS ETPPKYTSAL 
    TYDGVLVMAE TFRSLRRQKI DISRRGNAGD CLANPAAPWG QGIDMERTLK QVRIQGLTGN 
    VQFDHYGRRV NYTMDVFELK STGPRKVGYW NDMDKLVLIQ DVPTLGNDTA AIENRTVVVT 
    TIMESPYVMY KKNHEMFEGN DKYEGYCVDL ASEIAKHIGI KYKIAIVPDG KYGARDADTK 
    IWNGMVGELV YGKAEIAIAP LTITLVREEV IDFSKPFMSL GISIMIKKPQ KSKPGVFSFL 
    DPLAYEIWMC IVFAYIGVSV VLFLVSRFSP YEWHTEEPED GKEGPSDQPP NEFGIFNSLW 
    FSLGAFMQQG CDISPRSLSG RIVGGVWWFF TLIIISSYTA NLAAFLTVER MVSPIESAED 
    LAKQTEIAYG TLDSGSTKEF FRRSKIAVYE KMWTYMRSAE PSVFTRTTAE GVARVRKSKG 
    KFAFLLESTM NEYIEQRKPC DTMKVGGNLD SKGYGVATPK GSSLRTPVNL AVLKLSEAGV 
    LDKLKNKWWY DKGECGPKDS GSKDKTSALS LSNVAGVFYI LVGGLGLAML VALIEFCYKS 
    RAEAKRMKLT FSEAIRNKAR LSITGSVGEN GRVLTPDCPK AVHTGTAIRQ SSGLAVIASD 
    LP

Genular Protein ID: 250173704

Symbol: Q1WWK6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 883
  • Mass: 99019
  • Checksum: A5EB35FFD97A2126
  • Sequence:
  • RIISRQIVLL FSGFWGLAMG AFPSSVQIGG LFIRNTDQEY TAFRLAIFLH NTSPNASEAP 
    FNLVPHVDNI ETANSFAVTN AFCSQYSRGV FAIFGLYDKR SVHTLTSFCS ALHISLITPS 
    FPTEGESQFV LQLRPSLRGA LLSLLDHYEW NCFVFLYDTD RGYSILQAIM EKAGQNGWHV 
    SAICVENFND VSYRQLLEEL DRRQEKKFVI DCEIERLQNI LEQIVSVGKH VKGYHYIIAN 
    LGFKDISLER FIHGGANVTG FQLVDFNTPM VIKLMDRWKK LDQREYPGSE TPPKYTSALT 
    YDGVLVMAET FRSLRRQKID ISRRGNAGDC LANPAAPWGQ GIDMERTLKQ VRIQGLTGNV 
    QFDHYGRRVN YTMDVFELKS TGPRKVGYWN DMDKLVLIQD VPTLGNDTAA IENRTVVVTT 
    IMESPYVMYK KNHEMFEGND KYEGYCVDLA SEIAKHIGIK YKIAIVPDGK YGARDADTKI 
    WNGMVGELVY GKAEIAIAPL TITLVREEVI DFSKPFMSLG ISIMIKKPQK SKPGVFSFLD 
    PLAYEIWMCI VFAYIGVSVV LFLVSRFSPY EWHTEEPEDG KEGPSDQPPN EFGIFNSLWF 
    SLGAFMQQGC DISPRSLSGR IVGGVWWFFT LIIISSYTAN LAAFLTVERM VSPIESAEDL 
    AKQTEIAYGT LDSGSTKEFF RRSKIAVYEK MWTYMRSAEP SVFTRTTAEG VARVRKSKGK 
    FAFLLESTMN EYIEQRKPCD TMKVGGNLDS KGYGVATPKG SSLGNAVNLA VLKLNEQGLL 
    DKLKNKWWYD KGECGSGGGD SKDKTSALSL SNVAGVFYIL VGGLGLAMLV ALIEFCYKSR 
    AEAKRMKVAK SAQTFNPTSS QNTQNLATYR EGYNVYGTES IKI

Genular Protein ID: 1110834664

Symbol: A0A994J6J2_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

Sequence Information:

  • Length: 814
  • Mass: 91762
  • Checksum: F90A6A2A719BB1AF
  • Sequence:
  • MRIISRQIVL LFSGFWGLAM GAFPSSVQIG GLFIRNTDQE YTAFRLAIFL HNTSPNASEA 
    PFNLVPHVDN IETANSFAVT NAFCSQYSRG VFAIFGLYDK RSVHTLTSFC SALHISLITP 
    SFPTEGESQF VLQLRPSLRG ALLSLLDHYE WNCFVFLYDT DRGYSILQAI MEKAGQNGWH 
    VSAICVENFN DVSYRQLLEE LDRRQEKKFV IDCEIERLQN ILEQIVSVGK HVKGYHYIIA 
    NLGFKDISLE RFIHGGANVT GFQLVDFNTP MVIKLMDRWK KLDQREYPGS ETPPKYTSAL 
    TYDGVLVMAE TFRSLRRQKI DISRRGNAGD CLANPAAPWG QGIDMERTLK QVRIQGLTGN 
    VQFDHYGRRV NYTMDVFELK STGPRKVGYW NDMDKLVLIQ DVPTLGNDTA AIENRTVVVT 
    TIMESPYVMY KKNHEMFEGN DKYEGYCVDL ASEIAKHIGI KYKIAIVPDG KYGARDADTK 
    IWNGMVGELV YGKAEIAIAP LTITLVREEV IDFSKPFMSL GISIMIKKPQ KSKPGVFSFL 
    DPLAYEIWMC IVFAYIGVSV VLFLVSRFSP YEWHTEEPED GKEGPSDQPP NEFGIFNSLW 
    FSLGAFMQQG CDISPRSLSG RIVGGVWWFF TLIIISSYTA NLAAFLTVER MVSPIESAED 
    LAKQTEIAYG TLDSGSTKEF FRRSKIAVYE KMWTYMRSAE PSVFTRTTAE GVARVRKSKG 
    KFAFLLESTM NEYIEQRKPC DTMKVGGNLD SKGYGVATPK GSSLRNAVNL AVLKLNEQGL 
    LDKLKNKWWY DKGECGSGGG DSKNSCKPCR FETQ

Genular Protein ID: 2478379641

Symbol: A0A8D9PH77_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 34100982

Title: Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data.

PubMed ID: 34100982

DOI: 10.1007/s00018-021-03865-z

Sequence Information:

  • Length: 433
  • Mass: 49146
  • Checksum: 0013C833D25B75CE
  • Sequence:
  • MRIISRQIVL LFSGFWGLAM GAFPSSVQIG GLFIRNTDQE YTAFRLAIFL HNTSPNASEA 
    PFNLVPHVDN IETANSFAVT NAFCSQYSRG VFAIFGLYDK RSVHTLTSFC SALHISLITP 
    SFPTEGESQF VLQLRPSLRG ALLSLLDHYE WNCFVFLYDT DRGYSILQAI MEKAGQNGWH 
    VSAICVENFN DVSYRQLLEE LDRRQEKKFV IDCEIERLQN ILEQIVSVGK HVKGYHYIIA 
    NLGFKDISLE RFIHGGANVT GFQLVDFNTP MVIKLMDRWK KLDQREYPGS ETPPKYTSAL 
    TYDGVLVMAE TFRSLRRQKI DISRRGNAGD CLANPAAPWG QGIDMERTLK QVRIQGLTGN 
    VQFDHYGRRV NYTMDVFELK STGPRKVGYW NDMDKLVLIQ DVPTLGNDTA AIENRTVVVT 
    TIMPLMKNPI LRN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.