Details for: GRIA4
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 6.4676
Cell Significance Index: 362.9300 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 5.2530
Cell Significance Index: 125.9800 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 5.0306
Cell Significance Index: 86.2100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 3.5494
Cell Significance Index: 218.1700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 3.3557
Cell Significance Index: 225.6400 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 3.3056
Cell Significance Index: 663.1100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: 3.0903
Cell Significance Index: 162.2600 - Cell Name: midget ganglion cell of retina (CL4023188)
Fold Change: 2.8454
Cell Significance Index: 29.6400 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 2.7988
Cell Significance Index: 1935.7800 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.4755
Cell Significance Index: 887.9400 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 2.0241
Cell Significance Index: 26.2500 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: 1.1953
Cell Significance Index: 38.2900 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.7555
Cell Significance Index: 479.8000 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.6493
Cell Significance Index: 1222.5200 - Cell Name: OFF midget ganglion cell (CL4033047)
Fold Change: 0.6488
Cell Significance Index: 8.0900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.6188
Cell Significance Index: 1141.2900 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6092
Cell Significance Index: 550.0900 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.3489
Cell Significance Index: 34.5100 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2833
Cell Significance Index: 53.9200 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.1485
Cell Significance Index: 4.2800 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.0597
Cell Significance Index: 9.7000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.0265
Cell Significance Index: 40.7400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.0047
Cell Significance Index: 6.3700 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0627
Cell Significance Index: -46.4600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0655
Cell Significance Index: -36.9200 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0811
Cell Significance Index: -50.6500 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1064
Cell Significance Index: -3.7400 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: -0.1100
Cell Significance Index: -48.6500 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.1201
Cell Significance Index: -54.5300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.1296
Cell Significance Index: -98.0800 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.1654
Cell Significance Index: -90.3100 - Cell Name: ON midget ganglion cell (CL4033046)
Fold Change: -0.2060
Cell Significance Index: -2.6000 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: -0.2441
Cell Significance Index: -26.5500 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.2650
Cell Significance Index: -76.2600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.3333
Cell Significance Index: -70.2000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.3380
Cell Significance Index: -15.3200 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.3731
Cell Significance Index: -63.7100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.3764
Cell Significance Index: -74.6900 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.4076
Cell Significance Index: -8.6500 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.4333
Cell Significance Index: -62.9800 - Cell Name: retinal ganglion cell (CL0000740)
Fold Change: -0.4349
Cell Significance Index: -3.5900 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.4370
Cell Significance Index: -78.7800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.6127
Cell Significance Index: -84.1400 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.6411
Cell Significance Index: -78.8300 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.6569
Cell Significance Index: -40.2800 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.6644
Cell Significance Index: -85.8400 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.6811
Cell Significance Index: -7.4200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.7268
Cell Significance Index: -75.6800 - Cell Name: GABAergic amacrine cell (CL4030027)
Fold Change: -0.7466
Cell Significance Index: -9.2600 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.7595
Cell Significance Index: -52.5200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.8115
Cell Significance Index: -92.9700 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.8192
Cell Significance Index: -93.5100 - Cell Name: chandelier cell (CL4023083)
Fold Change: -0.8316
Cell Significance Index: -6.7200 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.8419
Cell Significance Index: -18.1900 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.8442
Cell Significance Index: -12.0900 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.8497
Cell Significance Index: -86.8000 - Cell Name: neural cell (CL0002319)
Fold Change: -0.9000
Cell Significance Index: -10.5000 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.9141
Cell Significance Index: -54.8800 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -1.0144
Cell Significance Index: -20.3700 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -1.0198
Cell Significance Index: -28.5000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -1.1327
Cell Significance Index: -71.3900 - Cell Name: neuron (CL0000540)
Fold Change: -1.1372
Cell Significance Index: -10.7800 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -1.1515
Cell Significance Index: -85.8200 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -1.2268
Cell Significance Index: -94.1400 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -1.2406
Cell Significance Index: -15.6600 - Cell Name: melanocyte of skin (CL1000458)
Fold Change: -1.2642
Cell Significance Index: -17.7200 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -1.2710
Cell Significance Index: -15.2000 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -1.3589
Cell Significance Index: -34.9300 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -1.3628
Cell Significance Index: -28.2700 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -1.3847
Cell Significance Index: -64.5600 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -1.4623
Cell Significance Index: -31.6800 - Cell Name: cerebral cortex neuron (CL0010012)
Fold Change: -1.4840
Cell Significance Index: -14.1200 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -1.5122
Cell Significance Index: -29.9000 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -1.5179
Cell Significance Index: -67.1400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -1.5443
Cell Significance Index: -80.4400 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -1.5528
Cell Significance Index: -50.8400 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -1.6766
Cell Significance Index: -78.8000 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -1.6849
Cell Significance Index: -42.0300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -1.7251
Cell Significance Index: -49.2300 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -1.7939
Cell Significance Index: -37.4400 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -1.9008
Cell Significance Index: -66.5900 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -1.9561
Cell Significance Index: -62.3000 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -2.0120
Cell Significance Index: -76.1900 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -2.2309
Cell Significance Index: -70.5600 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: -2.3717
Cell Significance Index: -35.7400 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -2.4114
Cell Significance Index: -88.5200 - Cell Name: granule cell (CL0000120)
Fold Change: -2.5315
Cell Significance Index: -28.8200 - Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
Fold Change: -2.6144
Cell Significance Index: -90.8500 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -2.7633
Cell Significance Index: -66.9400 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -2.8005
Cell Significance Index: -37.3300 - Cell Name: glycinergic amacrine cell (CL4030028)
Fold Change: -2.8529
Cell Significance Index: -30.6700 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -2.9022
Cell Significance Index: -38.7200 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -2.9167
Cell Significance Index: -50.4300 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -2.9917
Cell Significance Index: -85.7600 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -3.0060
Cell Significance Index: -80.2700 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -3.1248
Cell Significance Index: -92.0400 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -3.2045
Cell Significance Index: -79.9100 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -3.2110
Cell Significance Index: -68.3900 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -3.2224
Cell Significance Index: -80.5500 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -3.2250
Cell Significance Index: -70.6200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 874135712
Symbol: GRIA4_HUMAN
Name: AMPA-selective glutamate receptor 4
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8589990
Title: Cloning, expression and pharmacological characterization of a human glutamate receptor: hGluR4.
PubMed ID: 8589990
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 21172611
Title: Hippocampal AMPA receptor gating controlled by both TARP and cornichon proteins.
PubMed ID: 21172611
PubMed ID: 29220673
Title: De Novo Variants in GRIA4 Lead to Intellectual Disability with or without Seizures and Gait Abnormalities.
PubMed ID: 29220673
Sequence Information:
- Length: 902
- Mass: 100871
- Checksum: 7793AEF0AB829FC5
- Sequence:
MRIISRQIVL LFSGFWGLAM GAFPSSVQIG GLFIRNTDQE YTAFRLAIFL HNTSPNASEA PFNLVPHVDN IETANSFAVT NAFCSQYSRG VFAIFGLYDK RSVHTLTSFC SALHISLITP SFPTEGESQF VLQLRPSLRG ALLSLLDHYE WNCFVFLYDT DRGYSILQAI MEKAGQNGWH VSAICVENFN DVSYRQLLEE LDRRQEKKFV IDCEIERLQN ILEQIVSVGK HVKGYHYIIA NLGFKDISLE RFIHGGANVT GFQLVDFNTP MVIKLMDRWK KLDQREYPGS ETPPKYTSAL TYDGVLVMAE TFRSLRRQKI DISRRGNAGD CLANPAAPWG QGIDMERTLK QVRIQGLTGN VQFDHYGRRV NYTMDVFELK STGPRKVGYW NDMDKLVLIQ DVPTLGNDTA AIENRTVVVT TIMESPYVMY KKNHEMFEGN DKYEGYCVDL ASEIAKHIGI KYKIAIVPDG KYGARDADTK IWNGMVGELV YGKAEIAIAP LTITLVREEV IDFSKPFMSL GISIMIKKPQ KSKPGVFSFL DPLAYEIWMC IVFAYIGVSV VLFLVSRFSP YEWHTEEPED GKEGPSDQPP NEFGIFNSLW FSLGAFMQQG CDISPRSLSG RIVGGVWWFF TLIIISSYTA NLAAFLTVER MVSPIESAED LAKQTEIAYG TLDSGSTKEF FRRSKIAVYE KMWTYMRSAE PSVFTRTTAE GVARVRKSKG KFAFLLESTM NEYIEQRKPC DTMKVGGNLD SKGYGVATPK GSSLRTPVNL AVLKLSEAGV LDKLKNKWWY DKGECGPKDS GSKDKTSALS LSNVAGVFYI LVGGLGLAML VALIEFCYKS RAEAKRMKLT FSEAIRNKAR LSITGSVGEN GRVLTPDCPK AVHTGTAIRQ SSGLAVIASD LP
Genular Protein ID: 1110834664
Symbol: A0A994J6J2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11237011
Title: Initial sequencing and analysis of the human genome.
PubMed ID: 11237011
DOI: 10.1038/35057062
PubMed ID: 15496913
Title: Finishing the euchromatic sequence of the human genome.
PubMed ID: 15496913
DOI: 10.1038/nature03001
PubMed ID: 16554811
Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.
PubMed ID: 16554811
DOI: 10.1038/nature04632
Sequence Information:
- Length: 814
- Mass: 91762
- Checksum: F90A6A2A719BB1AF
- Sequence:
MRIISRQIVL LFSGFWGLAM GAFPSSVQIG GLFIRNTDQE YTAFRLAIFL HNTSPNASEA PFNLVPHVDN IETANSFAVT NAFCSQYSRG VFAIFGLYDK RSVHTLTSFC SALHISLITP SFPTEGESQF VLQLRPSLRG ALLSLLDHYE WNCFVFLYDT DRGYSILQAI MEKAGQNGWH VSAICVENFN DVSYRQLLEE LDRRQEKKFV IDCEIERLQN ILEQIVSVGK HVKGYHYIIA NLGFKDISLE RFIHGGANVT GFQLVDFNTP MVIKLMDRWK KLDQREYPGS ETPPKYTSAL TYDGVLVMAE TFRSLRRQKI DISRRGNAGD CLANPAAPWG QGIDMERTLK QVRIQGLTGN VQFDHYGRRV NYTMDVFELK STGPRKVGYW NDMDKLVLIQ DVPTLGNDTA AIENRTVVVT TIMESPYVMY KKNHEMFEGN DKYEGYCVDL ASEIAKHIGI KYKIAIVPDG KYGARDADTK IWNGMVGELV YGKAEIAIAP LTITLVREEV IDFSKPFMSL GISIMIKKPQ KSKPGVFSFL DPLAYEIWMC IVFAYIGVSV VLFLVSRFSP YEWHTEEPED GKEGPSDQPP NEFGIFNSLW FSLGAFMQQG CDISPRSLSG RIVGGVWWFF TLIIISSYTA NLAAFLTVER MVSPIESAED LAKQTEIAYG TLDSGSTKEF FRRSKIAVYE KMWTYMRSAE PSVFTRTTAE GVARVRKSKG KFAFLLESTM NEYIEQRKPC DTMKVGGNLD SKGYGVATPK GSSLRNAVNL AVLKLNEQGL LDKLKNKWWY DKGECGSGGG DSKNSCKPCR FETQ
Genular Protein ID: 2478379641
Symbol: A0A8D9PH77_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 34100982
Title: Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data.
PubMed ID: 34100982
Sequence Information:
- Length: 433
- Mass: 49146
- Checksum: 0013C833D25B75CE
- Sequence:
MRIISRQIVL LFSGFWGLAM GAFPSSVQIG GLFIRNTDQE YTAFRLAIFL HNTSPNASEA PFNLVPHVDN IETANSFAVT NAFCSQYSRG VFAIFGLYDK RSVHTLTSFC SALHISLITP SFPTEGESQF VLQLRPSLRG ALLSLLDHYE WNCFVFLYDT DRGYSILQAI MEKAGQNGWH VSAICVENFN DVSYRQLLEE LDRRQEKKFV IDCEIERLQN ILEQIVSVGK HVKGYHYIIA NLGFKDISLE RFIHGGANVT GFQLVDFNTP MVIKLMDRWK KLDQREYPGS ETPPKYTSAL TYDGVLVMAE TFRSLRRQKI DISRRGNAGD CLANPAAPWG QGIDMERTLK QVRIQGLTGN VQFDHYGRRV NYTMDVFELK STGPRKVGYW NDMDKLVLIQ DVPTLGNDTA AIENRTVVVT TIMPLMKNPI LRN
Genular Protein ID: 250173704
Symbol: Q1WWK6_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 883
- Mass: 99019
- Checksum: A5EB35FFD97A2126
- Sequence:
RIISRQIVLL FSGFWGLAMG AFPSSVQIGG LFIRNTDQEY TAFRLAIFLH NTSPNASEAP FNLVPHVDNI ETANSFAVTN AFCSQYSRGV FAIFGLYDKR SVHTLTSFCS ALHISLITPS FPTEGESQFV LQLRPSLRGA LLSLLDHYEW NCFVFLYDTD RGYSILQAIM EKAGQNGWHV SAICVENFND VSYRQLLEEL DRRQEKKFVI DCEIERLQNI LEQIVSVGKH VKGYHYIIAN LGFKDISLER FIHGGANVTG FQLVDFNTPM VIKLMDRWKK LDQREYPGSE TPPKYTSALT YDGVLVMAET FRSLRRQKID ISRRGNAGDC LANPAAPWGQ GIDMERTLKQ VRIQGLTGNV QFDHYGRRVN YTMDVFELKS TGPRKVGYWN DMDKLVLIQD VPTLGNDTAA IENRTVVVTT IMESPYVMYK KNHEMFEGND KYEGYCVDLA SEIAKHIGIK YKIAIVPDGK YGARDADTKI WNGMVGELVY GKAEIAIAPL TITLVREEVI DFSKPFMSLG ISIMIKKPQK SKPGVFSFLD PLAYEIWMCI VFAYIGVSVV LFLVSRFSPY EWHTEEPEDG KEGPSDQPPN EFGIFNSLWF SLGAFMQQGC DISPRSLSGR IVGGVWWFFT LIIISSYTAN LAAFLTVERM VSPIESAEDL AKQTEIAYGT LDSGSTKEFF RRSKIAVYEK MWTYMRSAEP SVFTRTTAEG VARVRKSKGK FAFLLESTMN EYIEQRKPCD TMKVGGNLDS KGYGVATPKG SSLGNAVNLA VLKLNEQGLL DKLKNKWWYD KGECGSGGGD SKDKTSALSL SNVAGVFYIL VGGLGLAMLV ALIEFCYKSR AEAKRMKVAK SAQTFNPTSS QNTQNLATYR EGYNVYGTES IKI
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.