Details for: CTNNA3

Gene ID: 29119

Symbol: CTNNA3

Ensembl ID: ENSG00000183230

Description: catenin alpha 3

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: 14.9533
    Cell Significance Index: 384.3700
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: 10.8175
    Cell Significance Index: 263.9400
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: 10.2851
    Cell Significance Index: 789.2600
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 9.8168
    Cell Significance Index: -21.4900
  • Cell Name: type II muscle cell (CL0002212)
    Fold Change: 7.2264
    Cell Significance Index: 116.6000
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 3.8015
    Cell Significance Index: 552.5900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 2.7624
    Cell Significance Index: 1910.5600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 2.0779
    Cell Significance Index: 116.6000
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 2.0720
    Cell Significance Index: 78.4600
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 2.0091
    Cell Significance Index: 64.3500
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 1.9933
    Cell Significance Index: 34.1600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 1.8310
    Cell Significance Index: 80.9900
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 1.7694
    Cell Significance Index: 354.9300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: 1.5954
    Cell Significance Index: 98.0600
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: 1.2497
    Cell Significance Index: 18.4500
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: 1.1742
    Cell Significance Index: 28.1600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: 1.0815
    Cell Significance Index: 23.1200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.9924
    Cell Significance Index: 355.9600
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.8031
    Cell Significance Index: 1512.2300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.7979
    Cell Significance Index: 158.3400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.6236
    Cell Significance Index: 16.7100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: 0.2069
    Cell Significance Index: 93.9100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.2002
    Cell Significance Index: 127.1400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.1716
    Cell Significance Index: 316.4200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1590
    Cell Significance Index: 30.2500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0899
    Cell Significance Index: 138.4400
  • Cell Name: cardiac endothelial cell (CL0010008)
    Fold Change: 0.0515
    Cell Significance Index: 0.7400
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0121
    Cell Significance Index: 16.4000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: -0.0358
    Cell Significance Index: -32.3300
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0358
    Cell Significance Index: -26.5500
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.0718
    Cell Significance Index: -0.7700
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0747
    Cell Significance Index: -54.7900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0857
    Cell Significance Index: -48.3500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0894
    Cell Significance Index: -67.7000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.1024
    Cell Significance Index: -55.9100
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1040
    Cell Significance Index: -6.9900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.1048
    Cell Significance Index: -65.4400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.1185
    Cell Significance Index: -21.3600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.1768
    Cell Significance Index: -50.8800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.2533
    Cell Significance Index: -43.2600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.2633
    Cell Significance Index: -42.8300
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.2703
    Cell Significance Index: -56.9300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: -0.2754
    Cell Significance Index: -29.9600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.2880
    Cell Significance Index: -29.9900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.3148
    Cell Significance Index: -38.7100
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.3255
    Cell Significance Index: -44.7000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.3469
    Cell Significance Index: -44.4700
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: -0.4204
    Cell Significance Index: -25.2400
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.4260
    Cell Significance Index: -55.0400
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.4637
    Cell Significance Index: -6.6400
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: -0.4693
    Cell Significance Index: -46.4200
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.4836
    Cell Significance Index: -57.0300
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.4965
    Cell Significance Index: -22.5100
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.5056
    Cell Significance Index: -58.9300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.5217
    Cell Significance Index: -14.5800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.5481
    Cell Significance Index: -62.8000
  • Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
    Fold Change: -0.5720
    Cell Significance Index: -7.6300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.5833
    Cell Significance Index: -59.5800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.5908
    Cell Significance Index: -36.2200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: -0.5992
    Cell Significance Index: -41.4400
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: -0.6134
    Cell Significance Index: -7.8700
  • Cell Name: corneal endothelial cell (CL0000132)
    Fold Change: -0.6488
    Cell Significance Index: -9.8700
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.6973
    Cell Significance Index: -55.2300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.7373
    Cell Significance Index: -54.9500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.7712
    Cell Significance Index: -25.2500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.8008
    Cell Significance Index: -28.1400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.8406
    Cell Significance Index: -17.8400
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.8509
    Cell Significance Index: -21.2700
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.8647
    Cell Significance Index: -27.5400
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.9618
    Cell Significance Index: -20.7800
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.9630
    Cell Significance Index: -50.1600
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -1.0247
    Cell Significance Index: -66.1100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -1.0311
    Cell Significance Index: -36.1200
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -1.0413
    Cell Significance Index: -21.6000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -1.0449
    Cell Significance Index: -54.8600
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -1.0570
    Cell Significance Index: -21.2200
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -1.0660
    Cell Significance Index: -30.4200
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -1.0733
    Cell Significance Index: -50.4500
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.1116
    Cell Significance Index: -70.0600
  • Cell Name: neural cell (CL0002319)
    Fold Change: -1.1141
    Cell Significance Index: -13.0000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -1.1217
    Cell Significance Index: -22.1800
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -1.1467
    Cell Significance Index: -33.0400
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -1.1846
    Cell Significance Index: -19.9600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -1.1862
    Cell Significance Index: -29.5900
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -1.2701
    Cell Significance Index: -55.2300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -1.2731
    Cell Significance Index: -15.7900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.2756
    Cell Significance Index: -27.6400
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -1.3409
    Cell Significance Index: -32.4800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -1.4220
    Cell Significance Index: -66.3000
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.4255
    Cell Significance Index: -74.0500
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -1.4642
    Cell Significance Index: -30.5600
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -1.4953
    Cell Significance Index: -54.8900
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -1.5072
    Cell Significance Index: -47.6700
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -1.6084
    Cell Significance Index: -23.7400
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.6104
    Cell Significance Index: -55.9600
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -1.6703
    Cell Significance Index: -25.1700
  • Cell Name: hippocampal interneuron (CL1001569)
    Fold Change: -1.6710
    Cell Significance Index: -21.6700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -1.6728
    Cell Significance Index: -43.9900
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -1.7349
    Cell Significance Index: -11.7600
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -1.7746
    Cell Significance Index: -16.8900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Cell Adhesion:** CTNNA3 is a cytoplasmic component of adherens junctions, which are critical for maintaining tissue structure and function. It interacts with β-catenin, cadherins, and other proteins to form a complex that mediates cell-cell adhesion. 2. **Signaling Pathways:** CTNNA3 is involved in various signaling pathways, including the Wnt/β-catenin pathway, which regulates cell proliferation, differentiation, and survival. It also interacts with other proteins to modulate cell migration and invasion. 3. **Expression Patterns:** CTNNA3 is highly expressed in epithelial cells, cardiac myocytes, and neurons, highlighting its importance in these cell types. 4. **Alternative Splicing:** CTNNA3 undergoes alternative splicing, resulting in multiple isoforms with distinct functions and expression patterns. **Pathways and Functions:** 1. **Actin Filament Binding:** CTNNA3 interacts with actin filaments to modulate cell shape and cytoskeletal dynamics. 2. **Adherens Junction:** CTNNA3 is a key component of adherens junctions, which are essential for maintaining tissue structure and function. 3. **Beta-catenin Binding:** CTNNA3 interacts with β-catenin to regulate cell-cell adhesion and signaling pathways. 4. **Bundle of His Cell-Purkinje Myocyte Adhesion:** CTNNA3 is involved in the adhesion of cardiac myocytes to the Bundle of His, a critical structure in the heart's electrical conduction system. 5. **Regulation of Heart Rate:** CTNNA3 is involved in regulating heart rate by modulating the action potential in ventricular cardiac myocytes. 6. **Cell Migration:** CTNNA3 is involved in cell migration, particularly in the context of epithelial-to-mesenchymal transition (EMT). **Clinical Significance:** 1. **Cardiac Arrhythmias:** Alterations in CTNNA3 expression or function have been implicated in cardiac arrhythmias, including atrial fibrillation and ventricular tachycardia. 2. **Cancer:** CTNNA3 is often upregulated in various cancers, including breast, lung, and colon cancer, where it promotes cell migration and invasion. 3. **Neurological Disorders:** CTNNA3 has been implicated in neurological disorders, including Alzheimer's disease and Parkinson's disease, where it regulates cell-cell adhesion and signaling pathways. 4. **Epithelial Dysfunctions:** CTNNA3 is involved in the regulation of epithelial function, and its dysregulation has been implicated in various epithelial disorders, including lung cancer and Barrett's esophagus. In conclusion, CTNNA3 is a multifaceted gene that plays a critical role in maintaining the integrity of various cell types, including epithelial cells, cardiac myocytes, and neurons. Its dysregulation has been implicated in various diseases, including cardiac arrhythmias, cancer, and neurological disorders. Further research is needed to fully elucidate the mechanisms by which CTNNA3 regulates cell-cell adhesion, signaling pathways, and heart function.

Genular Protein ID: 3842076129

Symbol: CTNA3_HUMAN

Name: Catenin alpha-3

UniProtKB Accession Codes:

Q9UI47 Q5VSR2 Q6P056

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 29 Ensembl 3 ExpressionAtlas 1 GO 14 Gene3D 2 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 3 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 2 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11590244

Title: AlphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion.

PubMed ID: 11590244

DOI: 10.1242/jcs.114.17.3177

PubMed ID: 12596047

Title: Assessment of the CTNNA3 gene encoding human alpha T-catenin regarding its involvement in dilated cardiomyopathy.

PubMed ID: 12596047

DOI: 10.1007/s00439-002-0857-5

PubMed ID: 15164054

Title: The DNA sequence and comparative analysis of human chromosome 10.

PubMed ID: 15164054

DOI: 10.1038/nature02462

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17535849

Title: A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs.

PubMed ID: 17535849

DOI: 10.1242/jcs.004713

PubMed ID: 18318008

Title: Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography.

PubMed ID: 18318008

DOI: 10.1002/pmic.200700884

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 23136403

Title: Mutations in the area composita protein alphaT-catenin are associated with arrhythmogenic right ventricular cardiomyopathy.

PubMed ID: 23136403

DOI: 10.1093/eurheartj/ehs373

Sequence Information:

  • Length: 895
  • Mass: 99809
  • Checksum: 269E6DFB4956BDFE
  • Sequence:
    • MSAETPITLN IDPQDLQVQT FTVEKLLEPL IIQVTTLVNC PQNPSSRKKG RSKRASVLLA 
SVEEATWNLL DKGEKIAQEA TVLKDELTAS LEEVRKESEA LKVSAERFTD DPCFLPKREA 
VVQAARALLA AVTRLLILAD MIDVMCLLQH VSAFQRTFES LKNVANKSDL QKTYQKLGKE 
LENLDYLAFK RQQDLKSPNQ RDEIAGARAS LKENSPLLHS ICSACLEHSD VASLKASKDT 
VCEEIQNALN VISNASQGIQ NMTTPPEPQA ATLGSALDEL ENLIVLNPLT VTEEEIRPSL 
EKRLEAIISG AALLADSSCT RDLHRERIIA ECNAIRQALQ DLLSEYMNNA GKKERSNTLN 
IALDNMCKKT RDLRRQLRKA IIDHVSDSFL DTTVPLLVLI EAAKNGREKE IKEYAAIFHE 
HTSRLVEVAN LACSMSTNED GIKIVKIAAN HLETLCPQII NAALALAARP KSQAVKNTME 
MYKRTWENHI HVLTEAVDDI TSIDDFLAVS ESHILEDVNK CIIALRDQDA DNLDRAAGAI 
RGRAARVAHI VTGEMDSYEP GAYTEGVMRN VNFLTSTVIP EFVTQVNVAL EALSKSSLNV 
LDDNQFVDIS KKIYDTIHDI RCSVMMIRTP EELEDVSDLE EEHEVRSHTS IQTEGKTDRA 
KMTQLPEAEK EKIAEQVADF KKVKSKLDAE IEIWDDTSND IIVLAKNMCM IMMEMTDFTR 
GKGPLKHTTD VIYAAKMISE SGSRMDVLAR QIANQCPDPS CKQDLLAYLE QIKFYSHQLK 
ICSQVKAEIQ NLGGELIMSA LDSVTSLIQA AKNLMNAVVQ TVKMSYIAST KIIRIQSPAG 
PRHPVVMWRM KAPAKKPLIK REKPEETCAA VRRGSAKKKI HPLQVMSEFR GRQIY

Genular Protein ID: 2863849382

Symbol: Q8WW10_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q8WW10

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 3 GO 8 Gene3D 2 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 1 RefSeq 2 SAM 1 SUPFAM 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 376
  • Mass: 41631
  • Checksum: 0656724AC2EA350B
  • Sequence:
    • MSAETPITLN IDPQDLQVQT FTVEKLLEPL IIQVTTLVNC PQNPSSRKKG RSKRASVLLA 
SVEEATWNLL DKGEKIAQEA TVLKDELTAS LEKVRKESEA LKVSAERFTD DPCFLPKREA 
VVQAARALLA AVTRLLILAD MIDVMCLLQH VSAFQRTFES LKNVANKSDL QKTYQKLGKE 
LENLDYLAFK RQQDLKSPNQ RDEIAGARAS LKENSPLLHS ICSACLEHSD VASLKASKDT 
VCEEIQNALN VISNASQGIQ NMTTPPEPQA ATLGSALDEL ENLIVLNPLT VTEEEIRPSL 
EKRLEAIISG AALLADSSCT RDLHRERIIA ECNAIRQALQ DLLSEYMNNL CNQKSDLGLT 
GVKIKLLEEC IIFWSL

Genular Protein ID: 4032640275

Symbol: A8K141_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K141

Database IDs:

ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 6 GO 4 Gene3D 2 InterPro 3 KEGG 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 RefSeq 2 SAM 2 SUPFAM 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 895
  • Mass: 99836
  • Checksum: 2D4509D0DE7E19EC
  • Sequence:
    • MSAETPITLN IDPQDLQVQT FTVEKLLEPL IIQVTTLVNC PQNPSSRKKG RSKRASVLLA 
SVEEATWNLL DKGEKIAQEA TVLKDELTAS LEEVRKESEA LKVSAERFTD DPCFLPKREA 
VVQAARALLA AVTRLLILAD MIDVMCLLQH VSAFQRTFES LKNVANKSDL QKTYQKLGKE 
LENLDYLAFK RQQDLKSPNQ RDEIAGARAS LKENSPLLHS ICSACLEHSD VASLKASKDT 
VCEEIQNALN VISNASQGIQ NMTTPPEPQA ATLGSALDEL ENLIVLNPLT VTEEEIRPSL 
EKRLEAIISG AALLADSSCT RDLHRERIIA ECNAIRQALQ DLLSEYMNNA GKKERSNTLN 
IALDNMCKKT RDLRRQLRKA IIDHVSDSFL DTTVPLLVLI EAAKNGREKE IKEYAAIFHE 
HTSRLVEVAN LACSMSTNED GIKIVKIAAN HLETLCPQII NAALALAARP KSQAVKNTME 
MYKRTWENHI HVLTEAVDDI TSIDDFLAVS ESHILEDVNK CIIALRDQDA DNLDRAAGAI 
RGRAARVAHI VTGEMDSYEP GAYTEGVMRN VNFLTSTVIP EFVTQVNVAL EALSKNSLNV 
LDDNQFVDIS KKIYDTIHDI RCSVMMIRTP EELEDVSDLE EEHEVRSHTS IQTEGKTDRA 
KMTQLPEAEK EKIAEQVADF KKVKSKLDAE IEIWDDTSND IIVLAKNMCM IMMEMTDFTR 
GKGPLKHTTD VIYAAKMISE SGSRMDVLAR QIANQCPDPS CKQDLLAYLE QIKFYSHQLK 
ICSQVKAEIQ NLGGELIMSA LDSVTSLIQA AKNLMNAVVQ TVKMSYIAST KIIRIQSPAG 
PRHPVVMWRM KAPAKKPLIK REKPEETCAA VRRGSAKKKI HPLQVMSEFR GRQIY

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.