Details for: HTR7
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: photoreceptor cell (CL0000210)
Fold Change: 1.4671
Cell Significance Index: 20.6100 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: 0.6479
Cell Significance Index: 18.4900 - Cell Name: hepatoblast (CL0005026)
Fold Change: 0.5092
Cell Significance Index: 8.5700 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.3742
Cell Significance Index: 258.7900 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.3145
Cell Significance Index: 3.8900 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.2928
Cell Significance Index: 15.2100 - Cell Name: hippocampal interneuron (CL1001569)
Fold Change: 0.2221
Cell Significance Index: 2.8800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.1957
Cell Significance Index: 39.2500 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.1495
Cell Significance Index: 26.9500 - Cell Name: Hofbauer cell (CL3000001)
Fold Change: 0.0834
Cell Significance Index: 0.6800 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.0499
Cell Significance Index: 3.0700 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.0108
Cell Significance Index: 0.2600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.0089
Cell Significance Index: 0.2300 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.0046
Cell Significance Index: 0.5600 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: 0.0038
Cell Significance Index: 0.0800 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.0014
Cell Significance Index: -0.0200 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0016
Cell Significance Index: -2.9800 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.0018
Cell Significance Index: -0.0300 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0018
Cell Significance Index: -3.3700 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0021
Cell Significance Index: -3.2200 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0023
Cell Significance Index: -0.8100 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0025
Cell Significance Index: -3.3700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0036
Cell Significance Index: -0.2400 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0060
Cell Significance Index: -3.7900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0069
Cell Significance Index: -5.1500 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0086
Cell Significance Index: -4.7200 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0089
Cell Significance Index: -4.0600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0092
Cell Significance Index: -5.1700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0117
Cell Significance Index: -3.3800 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0149
Cell Significance Index: -2.9500 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.0170
Cell Significance Index: -2.1800 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0208
Cell Significance Index: -3.0300 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0227
Cell Significance Index: -0.9900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0248
Cell Significance Index: -5.2300 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0259
Cell Significance Index: -2.6500 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0268
Cell Significance Index: -0.5300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0273
Cell Significance Index: -4.6700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0304
Cell Significance Index: -4.1700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.0339
Cell Significance Index: -4.3800 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: -0.0344
Cell Significance Index: -0.4700 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.0380
Cell Significance Index: -0.8200 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0436
Cell Significance Index: -5.0000 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0462
Cell Significance Index: -4.8100 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0488
Cell Significance Index: -2.7400 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0517
Cell Significance Index: -1.6500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.0524
Cell Significance Index: -4.0200 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0551
Cell Significance Index: -4.1100 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.0565
Cell Significance Index: -1.5800 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: -0.0598
Cell Significance Index: -1.4900 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0605
Cell Significance Index: -2.1200 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: -0.0627
Cell Significance Index: -0.8600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0628
Cell Significance Index: -2.9300 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.0670
Cell Significance Index: -0.8500 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0698
Cell Significance Index: -4.5000 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0718
Cell Significance Index: -2.3500 - Cell Name: neural cell (CL0002319)
Fold Change: -0.0737
Cell Significance Index: -0.8600 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.0760
Cell Significance Index: -3.9900 - Cell Name: neuron (CL0000540)
Fold Change: -0.0770
Cell Significance Index: -0.7300 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0796
Cell Significance Index: -3.7400 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.0835
Cell Significance Index: -0.9100 - Cell Name: mature alpha-beta T cell (CL0000791)
Fold Change: -0.0853
Cell Significance Index: -0.4700 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: -0.0921
Cell Significance Index: -3.3800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.0936
Cell Significance Index: -2.5100 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.1031
Cell Significance Index: -4.5600 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.1153
Cell Significance Index: -2.2700 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.1191
Cell Significance Index: -2.9700 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1204
Cell Significance Index: -4.5600 - Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
Fold Change: -0.1238
Cell Significance Index: -1.6500 - Cell Name: inhibitory interneuron (CL0000498)
Fold Change: -0.1246
Cell Significance Index: -1.4900 - Cell Name: ganglion interneuron (CL0000397)
Fold Change: -0.1338
Cell Significance Index: -1.1000 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.1347
Cell Significance Index: -2.8200 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.1353
Cell Significance Index: -4.7600 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: -0.1373
Cell Significance Index: -3.6800 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.1429
Cell Significance Index: -4.5200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.1446
Cell Significance Index: -2.4200 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron of the primary motor cortex (CL4023050)
Fold Change: -0.1447
Cell Significance Index: -1.9300 - Cell Name: kidney epithelial cell (CL0002518)
Fold Change: -0.1494
Cell Significance Index: -4.4000 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.1497
Cell Significance Index: -4.2900 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.1509
Cell Significance Index: -1.3900 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.1509
Cell Significance Index: -3.0300 - Cell Name: fast muscle cell (CL0000190)
Fold Change: -0.1527
Cell Significance Index: -2.0000 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.1543
Cell Significance Index: -3.9300 - Cell Name: Purkinje cell (CL0000121)
Fold Change: -0.1589
Cell Significance Index: -3.4800 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.1610
Cell Significance Index: -4.3000 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.1619
Cell Significance Index: -2.3500 - Cell Name: type II muscle cell (CL0002212)
Fold Change: -0.1636
Cell Significance Index: -2.6400 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.1639
Cell Significance Index: -4.4600 - Cell Name: intratelencephalic-projecting glutamatergic cortical neuron (CL4023008)
Fold Change: -0.1663
Cell Significance Index: -1.7100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.1664
Cell Significance Index: -4.8000 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.1672
Cell Significance Index: -3.4900 - Cell Name: cytotoxic T cell (CL0000910)
Fold Change: -0.1702
Cell Significance Index: -2.4800 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.1742
Cell Significance Index: -3.4000 - Cell Name: type I muscle cell (CL0002211)
Fold Change: -0.1758
Cell Significance Index: -4.2900 - Cell Name: L6 intratelencephalic projecting glutamatergic neuron (CL4030065)
Fold Change: -0.1780
Cell Significance Index: -1.8600 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.1799
Cell Significance Index: -4.7300 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.1815
Cell Significance Index: -3.8800 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.1841
Cell Significance Index: -4.4600 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1844
Cell Significance Index: -4.7100 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.1882
Cell Significance Index: -4.7000 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.1941
Cell Significance Index: -3.9500
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1696171577
Symbol: 5HT7R_HUMAN
Name: 5-HT-X
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9084407
Title: Four 5-hydroxytryptamine7 (5-HT7) receptor isoforms in human and rat produced by alternative splicing: species differences due to altered intron-exon organization.
PubMed ID: 9084407
PubMed ID: 8226867
Title: Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.
PubMed ID: 8226867
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 19054851
Title: Human protein factory for converting the transcriptome into an in vitro-expressed proteome.
PubMed ID: 19054851
DOI: 10.1038/nmeth.1273
PubMed ID: 15164054
Title: The DNA sequence and comparative analysis of human chromosome 10.
PubMed ID: 15164054
DOI: 10.1038/nature02462
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 22448645
Title: Biochemical and pharmacological study of N-linked glycosylation of the human serotonin 5-HT(7)a receptor.
PubMed ID: 22448645
PubMed ID: 35714614
Title: GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors.
PubMed ID: 35714614
PubMed ID: 9154233
Title: The human serotonin 7 (5-HT7) receptor gene: genomic organization and systematic mutation screening in schizophrenia and bipolar affective disorder.
PubMed ID: 9154233
Sequence Information:
- Length: 479
- Mass: 53555
- Checksum: 1F62E985EADE1F23
- Sequence:
MMDVNSSGRP DLYGHLRSFL LPEVGRGLPD LSPDGGADPV AGSWAPHLLS EVTASPAPTW DAPPDNASGC GEQINYGRVE KVVIGSILTL ITLLTIAGNC LVVISVCFVK KLRQPSNYLI VSLALADLSV AVAVMPFVSV TDLIGGKWIF GHFFCNVFIA MDVMCCTASI MTLCVISIDR YLGITRPLTY PVRQNGKCMA KMILSVWLLS ASITLPPLFG WAQNVNDDKV CLISQDFGYT IYSTAVAFYI PMSVMLFMYY QIYKAARKSA AKHKFPGFPR VEPDSVIALN GIVKLQKEVE ECANLSRLLK HERKNISIFK REQKAATTLG IIVGAFTVCW LPFFLLSTAR PFICGTSCSC IPLWVERTFL WLGYANSLIN PFIYAFFNRD LRTTYRSLLQ CQYRNINRKL SAAGMHEALK LAERPERPEF VLRACTRRVL LRPEKRPPVS VWVLQSPDHH NWLADKMLTT VEKKVMIHD
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.