Details for: IMPG1

Gene ID: 3617

Symbol: IMPG1

Ensembl ID: ENSG00000112706

Description: interphotoreceptor matrix proteoglycan 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 16.2613
    Cell Significance Index: 228.3900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 10.5641
    Cell Significance Index: 665.8200
  • Cell Name: hematopoietic stem cell (CL0000037)
    Fold Change: 3.7651
    Cell Significance Index: 64.3600
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 2.2854
    Cell Significance Index: 31.3400
  • Cell Name: retinal cone cell (CL0000573)
    Fold Change: 1.1239
    Cell Significance Index: 14.0300
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 1.0833
    Cell Significance Index: 26.2400
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 0.7996
    Cell Significance Index: -1.7500
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: 0.2061
    Cell Significance Index: 5.1400
  • Cell Name: retinal bipolar neuron (CL0000748)
    Fold Change: 0.1600
    Cell Significance Index: 1.9400
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.1255
    Cell Significance Index: 2.1500
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0898
    Cell Significance Index: 1.0700
  • Cell Name: OFF-bipolar cell (CL0000750)
    Fold Change: 0.0670
    Cell Significance Index: 0.5900
  • Cell Name: retinal ganglion cell (CL0000740)
    Fold Change: 0.0666
    Cell Significance Index: 0.5500
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.0569
    Cell Significance Index: 0.8400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0530
    Cell Significance Index: 10.6300
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 0.0306
    Cell Significance Index: 0.3800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.0235
    Cell Significance Index: 0.8900
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: 0.0215
    Cell Significance Index: 0.6800
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.0203
    Cell Significance Index: 2.3600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0144
    Cell Significance Index: 2.5900
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0125
    Cell Significance Index: 8.6200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.0072
    Cell Significance Index: 0.3200
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.0050
    Cell Significance Index: 0.6100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0043
    Cell Significance Index: 0.8600
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0035
    Cell Significance Index: 5.3200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0029
    Cell Significance Index: 5.4300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0025
    Cell Significance Index: 4.5300
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0025
    Cell Significance Index: 3.3400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0012
    Cell Significance Index: -0.2100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0018
    Cell Significance Index: -1.1500
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0021
    Cell Significance Index: -0.0300
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0023
    Cell Significance Index: -0.8300
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0044
    Cell Significance Index: -0.4500
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0055
    Cell Significance Index: -4.0500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0055
    Cell Significance Index: -3.0300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0056
    Cell Significance Index: -4.0700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0058
    Cell Significance Index: -2.6400
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0063
    Cell Significance Index: -0.9200
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0067
    Cell Significance Index: -0.2900
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0071
    Cell Significance Index: -3.9900
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0075
    Cell Significance Index: -4.7100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0076
    Cell Significance Index: -2.1800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0086
    Cell Significance Index: -0.4000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0093
    Cell Significance Index: -0.5200
  • Cell Name: rod bipolar cell (CL0000751)
    Fold Change: -0.0098
    Cell Significance Index: -0.1100
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: -0.0130
    Cell Significance Index: -0.1000
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0149
    Cell Significance Index: -0.7800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0176
    Cell Significance Index: -0.2400
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.0186
    Cell Significance Index: -0.2100
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.0190
    Cell Significance Index: -0.2700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0219
    Cell Significance Index: -4.6200
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0231
    Cell Significance Index: -3.1700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0275
    Cell Significance Index: -3.1500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0293
    Cell Significance Index: -1.5200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0303
    Cell Significance Index: -1.8600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0323
    Cell Significance Index: -3.3600
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.0358
    Cell Significance Index: -0.5200
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0373
    Cell Significance Index: -0.9600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0388
    Cell Significance Index: -2.9800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0446
    Cell Significance Index: -3.0000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0465
    Cell Significance Index: -1.3400
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.0509
    Cell Significance Index: -4.0300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0512
    Cell Significance Index: -1.0000
  • Cell Name: cone retinal bipolar cell (CL0000752)
    Fold Change: -0.0519
    Cell Significance Index: -0.4000
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0542
    Cell Significance Index: -1.0600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0584
    Cell Significance Index: -2.7500
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0586
    Cell Significance Index: -2.0600
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0591
    Cell Significance Index: -0.5600
  • Cell Name: retinal astrocyte (CL4033015)
    Fold Change: -0.0613
    Cell Significance Index: -0.6000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0670
    Cell Significance Index: -1.3900
  • Cell Name: neural cell (CL0002319)
    Fold Change: -0.0677
    Cell Significance Index: -0.7900
  • Cell Name: S cone cell (CL0003050)
    Fold Change: -0.0678
    Cell Significance Index: -0.7900
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0688
    Cell Significance Index: -2.4100
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0701
    Cell Significance Index: -1.7500
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0705
    Cell Significance Index: -1.9200
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0717
    Cell Significance Index: -2.0000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0719
    Cell Significance Index: -2.2900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0733
    Cell Significance Index: -2.6900
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0734
    Cell Significance Index: -1.8700
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0770
    Cell Significance Index: -2.5200
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0780
    Cell Significance Index: -1.0400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0820
    Cell Significance Index: -1.7400
  • Cell Name: amacrine cell (CL0000561)
    Fold Change: -0.0838
    Cell Significance Index: -1.0500
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0852
    Cell Significance Index: -2.0800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0858
    Cell Significance Index: -3.8900
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0869
    Cell Significance Index: -1.8200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0894
    Cell Significance Index: -2.4000
  • Cell Name: retina horizontal cell (CL0000745)
    Fold Change: -0.0909
    Cell Significance Index: -1.1400
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0917
    Cell Significance Index: -1.8400
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0926
    Cell Significance Index: -1.5000
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0931
    Cell Significance Index: -1.8400
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.0938
    Cell Significance Index: -1.1700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0948
    Cell Significance Index: -2.5300
  • Cell Name: ON midget ganglion cell (CL4033046)
    Fold Change: -0.0951
    Cell Significance Index: -1.2000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0952
    Cell Significance Index: -1.7600
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0973
    Cell Significance Index: -2.1300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0988
    Cell Significance Index: -2.3700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.1004
    Cell Significance Index: -2.1700
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.1006
    Cell Significance Index: -2.5100
  • Cell Name: pulmonary capillary endothelial cell (CL4028001)
    Fold Change: -0.1015
    Cell Significance Index: -1.3900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** IMPG1 is a proteoglycan, a type of glycoprotein that contains covalently attached glycosaminoglycan (GAG) chains. Its unique structure allows it to bind to various ECM components, including chondroitin sulfate, hyaluronic acid, and heparin. IMPG1 is specifically expressed in cells of the hematopoietic system, including erythrocytes, megakaryocytes, and thymocytes, as well as in photoreceptor cells of the retina. **Pathways and Functions:** IMPG1 is involved in several key pathways that regulate ECM organization and immune function: 1. **Extracellular Matrix Organization:** IMPG1 interacts with ECM components to maintain the structural integrity of tissues, including the retina and blood vessels. 2. **Hyaluronic Acid Binding:** IMPG1 binds to hyaluronic acid, a key component of the ECM, to regulate its activity and modulate immune responses. 3. **Chondroitin Sulfate Binding:** IMPG1 interacts with chondroitin sulfate, a GAG that plays a critical role in ECM organization and immune regulation. 4. **Photoreceptor Function:** IMPG1 is specifically expressed in photoreceptor cells of the retina, where it plays a role in maintaining the structure and function of the photoreceptor inner segment. **Clinical Significance:** Dysregulation of IMPG1 has been implicated in various diseases, including: 1. **Retinal Degeneration:** IMPG1 mutations have been linked to retinal degeneration and vision loss. 2. **Immune Disorders:** IMPG1 plays a role in regulating immune responses, and its dysregulation has been implicated in autoimmune diseases, such as multiple sclerosis. 3. **Hematopoietic Disorders:** IMPG1 is expressed in hematopoietic stem cells and progenitor cells, and its dysregulation has been linked to hematopoietic malignancies. In conclusion, IMPG1 is a critical component of the extracellular matrix that plays a significant role in immune regulation and tissue organization. Its dysregulation has been implicated in various diseases, highlighting the importance of further research into the mechanisms of IMPG1 and its role in human health and disease.

Genular Protein ID: 3700912254

Symbol: IMPG1_HUMAN

Name: Interphotoreceptor matrix proteoglycan 1

UniProtKB Accession Codes:

Q17R60 A6NNZ6 O43686 O95094 Q68D53 Q9BWZ1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 24 Ensembl 1 ExpressionAtlas 1 GO 11 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 5 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 3 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 2 RNAct 1 RefSeq 2 SMART 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 9691169

Title: Genomic organization and chromosomal localization of the interphotoreceptor matrix proteoglycan-1 (IMPG1) gene: a candidate for 6q-linked retinopathies.

PubMed ID: 9691169

DOI: 10.1159/000015001

PubMed ID: 10601738

Title: Expression and characterization of the IPM 150 gene (IMPG1) product, a novel human photoreceptor cell-associated chondroitin-sulfate proteoglycan.

PubMed ID: 10601738

DOI: 10.1016/s0945-053x(99)00043-8

PubMed ID: 17974005

Title: The full-ORF clone resource of the German cDNA consortium.

PubMed ID: 17974005

DOI: 10.1186/1471-2164-8-399

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9813076

Title: SPACR, a novel interphotoreceptor matrix glycoprotein in human retina that interacts with hyaluronan.

PubMed ID: 9813076

DOI: 10.1074/jbc.273.47.31599

PubMed ID: 9719680

Title: Characterization of SPACR, a sialoprotein associated with cones and rods present in the interphotoreceptor matrix of the human retina: immunological and lectin binding analysis.

PubMed ID: 9719680

DOI: 10.1093/glycob/8.10.997

PubMed ID: 29777959

Title: Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matrix.

PubMed ID: 29777959

DOI: 10.1016/j.actbio.2018.05.023

PubMed ID: 14691150

Title: The benign concentric annular macular dystrophy locus maps to 6p12.3-q16.

PubMed ID: 14691150

DOI: 10.1167/iovs.03-0392

PubMed ID: 23993198

Title: Mutations in IMPG1 cause vitelliform macular dystrophies.

PubMed ID: 23993198

DOI: 10.1016/j.ajhg.2013.07.018

PubMed ID: 25085631

Title: Frequency and clinical pattern of vitelliform macular dystrophy caused by mutations of interphotoreceptor matrix IMPG1 and IMPG2 genes.

PubMed ID: 25085631

DOI: 10.1016/j.ophtha.2014.06.028

PubMed ID: 28644393

Title: Mutations in the Genes for Interphotoreceptor Matrix Proteoglycans, IMPG1 and IMPG2, in Patients with Vitelliform Macular Lesions.

PubMed ID: 28644393

DOI: 10.3390/genes8070170

PubMed ID: 32817297

Title: Pathogenic variants in IMPG1 cause autosomal dominant and autosomal recessive retinitis pigmentosa.

PubMed ID: 32817297

DOI: 10.1136/jmedgenet-2020-107150

PubMed ID: 30688845

Title: Unusual early-onset vitelliform dystrophy possibly linked to the interphotoreceptor matrix proteoglycan-1 p.Leu154Pro mutation.

PubMed ID: 30688845

DOI: 10.1097/icb.0000000000000843

Sequence Information:

  • Length: 797
  • Mass: 89387
  • Checksum: D017ED090C78D521
  • Sequence:
    • MYLETRRAIF VFWIFLQVQG TKDISINIYH SETKDIDNPP RNETTESTEK MYKMSTMRRI 
FDLAKHRTKR SAFFPTGVKV CPQESMKQIL DSLQAYYRLR VCQEAVWEAY RIFLDRIPDT 
GEYQDWVSIC QQETFCLFDI GKNFSNSQEH LDLLQQRIKQ RSFPDRKDEI SAEKTLGEPG 
ETIVISTDVA NVSLGPFPLT PDDTLLNEIL DNTLNDTKMP TTERETEFAV LEEQRVELSV 
SLVNQKFKAE LADSQSPYYQ ELAGKSQLQM QKIFKKLPGF KKIHVLGFRP KKEKDGSSST 
EMQLTAIFKR HSAEAKSPAS DLLSFDSNKI ESEEVYHGTM EEDKQPEIYL TATDLKRLIS 
KALEEEQSLD VGTIQFTDEI AGSLPAFGPD TQSELPTSFA VITEDATLSP ELPPVEPQLE 
TVDGAEHGLP DTSWSPPAMA STSLSEAPPF FMASSIFSLT DQGTTDTMAT DQTMLVPGLT 
IPTSDYSAIS QLALGISHPP ASSDDSRSSA GGEDMVRHLD EMDLSDTPAP SEVPELSEYV 
SVPDHFLEDT TPVSALQYIT TSSMTIAPKG RELVVFFSLR VANMAFSNDL FNKSSLEYRA 
LEQQFTQLLV PYLRSNLTGF KQLEILNFRN GSVIVNSKMK FAKSVPYNLT KAVHGVLEDF 
RSAAAQQLHL EIDSYSLNIE PADQADPCKF LACGEFAQCV KNERTEEAEC RCKPGYDSQG 
SLDGLEPGLC GPGTKECEVL QGKGAPCRLP DHSENQAYKT SVKKFQNQQN NKVISKRNSE 
LLTVEYEEFN HQDWEGN

Genular Protein ID: 3045516207

Symbol: A0A087WYL3_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A087WYL3

Database IDs:

ARBA 13 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 Ensembl 2 ExpressionAtlas 1 GO 7 Gene3D 1 GeneTree 1 HGNC 1 InterPro 4 MassIVE 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PROSITE 4 PROSITE-ProRule 1 PeptideAtlas 2 Pfam 1 Proteomes 2 ProteomicsDB 1 RefSeq 1 SAM 1 SMART 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 719
  • Mass: 80147
  • Checksum: 547304511C058F3A
  • Sequence:
    • MYLETRRAIF VFWIFLQVQG TKVCQEAVWE AYRIFLDRIP DTGEYQDWVS ICQQETFCLF 
DIGKNFSNSQ EHLDLLQQRI KQRSFPDRKD EISAEKTLGE PGETIVISTD VANVSLGPFP 
LTPDDTLLNE ILDNTLNDTK MPTTERETEF AVLEEQRVEL SVSLVNQKFK AELADSQSPY 
YQELAGKSQL QMQKIFKKLP GFKKIHVLGF RPKKEKDGSS STEMQLTAIF KRHSAEAKSP 
ASDLLSFDSN KIESEEVYHG TMEEDKQPEI YLTATDLKRL ISKALEEEQS LDVGTIQFTD 
EIAGSLPAFG PDTQSELPTS FAVITEDATL SPELPPVEPQ LETVDGAEHG LPDTSWSPPA 
MASTSLSEAP PFFMASSIFS LTDQGTTDTM ATDQTMLVPG LTIPTSDYSA ISQLALGISH 
PPASSDDSRS SAGGEDMVRH LDEMDLSDTP APSEVPELSE YVSVPDHFLE DTTPVSALQY 
ITTSSMTIAP KGRELVVFFS LRVANMAFSN DLFNKSSLEY RALEQQFTQL LVPYLRSNLT 
GFKQLEILNF RNGSVIVNSK MKFAKSVPYN LTKAVHGVLE DFRSAAAQQL HLEIDSYSLN 
IEPADQADPC KFLACGEFAQ CVKNERTEEA ECRCKPGYDS QGSLDGLEPG LCGPGTKECE 
VLQGKGAPCR LPDHSENQAY KTSVKKFQNQ QNNKVISKRN SELLTVEYEE FNHQDWEGN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.