Details for: ITGAD
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: uterine smooth muscle cell (CL0002601)
Fold Change: 1.1751
Cell Significance Index: 11.2500 - Cell Name: type II muscle cell (CL0002212)
Fold Change: 0.5882
Cell Significance Index: 9.4900 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.5558
Cell Significance Index: 13.5600 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 0.5373
Cell Significance Index: 13.8100 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: 0.4778
Cell Significance Index: 1.2800 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.3065
Cell Significance Index: 8.2000 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: 0.1644
Cell Significance Index: 2.3600 - Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
Fold Change: 0.0862
Cell Significance Index: 2.1500 - Cell Name: ON-bipolar cell (CL0000749)
Fold Change: 0.0788
Cell Significance Index: 0.8900 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.0784
Cell Significance Index: 6.0200 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 0.0776
Cell Significance Index: 2.0800 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.0562
Cell Significance Index: 1.2300 - Cell Name: CD8-alpha alpha positive, gamma-delta intraepithelial T cell (CL0000802)
Fold Change: 0.0414
Cell Significance Index: 0.2400 - Cell Name: photoreceptor cell (CL0000210)
Fold Change: 0.0278
Cell Significance Index: 0.3900 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: 0.0274
Cell Significance Index: 0.4700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0255
Cell Significance Index: 5.0700 - Cell Name: epithelial cell of uterus (CL0002149)
Fold Change: 0.0209
Cell Significance Index: 0.2900 - Cell Name: OFF-bipolar cell (CL0000750)
Fold Change: 0.0204
Cell Significance Index: 0.1800 - Cell Name: hepatoblast (CL0005026)
Fold Change: 0.0184
Cell Significance Index: 0.3100 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: 0.0169
Cell Significance Index: 4.8800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.0138
Cell Significance Index: 2.7800 - Cell Name: mesangial cell (CL0000650)
Fold Change: 0.0126
Cell Significance Index: 0.1600 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0062
Cell Significance Index: 2.7300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.0048
Cell Significance Index: 0.8700 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.0002
Cell Significance Index: 0.4200 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.0001
Cell Significance Index: 0.1900 - Cell Name: professional antigen presenting cell (CL0000145)
Fold Change: 0.0000
Cell Significance Index: 0.0000 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0002
Cell Significance Index: -0.2400 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0003
Cell Significance Index: -0.4600 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0012
Cell Significance Index: -0.5500 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0013
Cell Significance Index: -0.8500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0017
Cell Significance Index: -0.6300 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0020
Cell Significance Index: -1.5500 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.0020
Cell Significance Index: -0.0900 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0022
Cell Significance Index: -0.3200 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0022
Cell Significance Index: -1.6300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0027
Cell Significance Index: -1.6900 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0029
Cell Significance Index: -1.6300 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0038
Cell Significance Index: -0.6500 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.0040
Cell Significance Index: -0.4700 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0049
Cell Significance Index: -0.6700 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.0058
Cell Significance Index: -0.3900 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0074
Cell Significance Index: -0.9100 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0080
Cell Significance Index: -1.6800 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0093
Cell Significance Index: -0.9500 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.0111
Cell Significance Index: -1.2700 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.0130
Cell Significance Index: -1.3500 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.0149
Cell Significance Index: -0.2200 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: -0.0154
Cell Significance Index: -0.1900 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.0193
Cell Significance Index: -0.3100 - Cell Name: regular ventricular cardiac myocyte (CL0002131)
Fold Change: -0.0195
Cell Significance Index: -0.2500 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0224
Cell Significance Index: -0.9900 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.0230
Cell Significance Index: -1.2900 - Cell Name: early pro-B cell (CL0002046)
Fold Change: -0.0234
Cell Significance Index: -1.5100 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.0236
Cell Significance Index: -1.4500 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0238
Cell Significance Index: -1.1100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.0240
Cell Significance Index: -1.1300 - Cell Name: cerebral cortex endothelial cell (CL1001602)
Fold Change: -0.0241
Cell Significance Index: -0.4900 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.0243
Cell Significance Index: -0.9200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.0246
Cell Significance Index: -1.2800 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: -0.0268
Cell Significance Index: -0.6500 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.0279
Cell Significance Index: -0.8900 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.0283
Cell Significance Index: -0.9900 - Cell Name: erythroid progenitor cell (CL0000038)
Fold Change: -0.0283
Cell Significance Index: -0.3700 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0300
Cell Significance Index: -0.9600 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.0305
Cell Significance Index: -1.0000 - Cell Name: fast muscle cell (CL0000190)
Fold Change: -0.0313
Cell Significance Index: -0.4100 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0338
Cell Significance Index: -0.6600 - Cell Name: precursor B cell (CL0000817)
Fold Change: -0.0348
Cell Significance Index: -0.4500 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: -0.0413
Cell Significance Index: -0.6000 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0418
Cell Significance Index: -1.4700 - Cell Name: slow muscle cell (CL0000189)
Fold Change: -0.0421
Cell Significance Index: -0.6300 - Cell Name: glutamatergic neuron (CL0000679)
Fold Change: -0.0422
Cell Significance Index: -0.4600 - Cell Name: lens fiber cell (CL0011004)
Fold Change: -0.0432
Cell Significance Index: -1.3700 - Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
Fold Change: -0.0433
Cell Significance Index: -1.0800 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.0454
Cell Significance Index: -0.6700 - Cell Name: GABAergic neuron (CL0000617)
Fold Change: -0.0460
Cell Significance Index: -0.5800 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.0471
Cell Significance Index: -1.0000 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.0484
Cell Significance Index: -2.4500 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: -0.0485
Cell Significance Index: -0.7100 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0486
Cell Significance Index: -1.4000 - Cell Name: cell of skeletal muscle (CL0000188)
Fold Change: -0.0492
Cell Significance Index: -0.6300 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0506
Cell Significance Index: -1.0500 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0508
Cell Significance Index: -1.4500 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.0509
Cell Significance Index: -1.1000 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.0509
Cell Significance Index: -1.3600 - Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: -0.0511
Cell Significance Index: -1.3900 - Cell Name: Kupffer cell (CL0000091)
Fold Change: -0.0530
Cell Significance Index: -0.4900 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: -0.0534
Cell Significance Index: -1.5300 - Cell Name: regular atrial cardiac myocyte (CL0002129)
Fold Change: -0.0541
Cell Significance Index: -0.7300 - Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
Fold Change: -0.0551
Cell Significance Index: -1.1500 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: -0.0552
Cell Significance Index: -1.6200 - Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
Fold Change: -0.0562
Cell Significance Index: -0.7700 - Cell Name: erythrocyte (CL0000232)
Fold Change: -0.0573
Cell Significance Index: -1.4600 - Cell Name: keratinocyte (CL0000312)
Fold Change: -0.0573
Cell Significance Index: -1.4300 - Cell Name: sncg GABAergic cortical interneuron (CL4023015)
Fold Change: -0.0584
Cell Significance Index: -1.1500 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.0593
Cell Significance Index: -1.1900 - Cell Name: muscle cell (CL0000187)
Fold Change: -0.0596
Cell Significance Index: -0.5700 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.0602
Cell Significance Index: -1.1900 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: -0.0606
Cell Significance Index: -0.7800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 920222534
Symbol: ITAD_HUMAN
Name: Integrin alpha-D
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8777714
Title: A novel leukointegrin, alpha d beta 2, binds preferentially to ICAM-3.
PubMed ID: 8777714
PubMed ID: 10722744
Title: Structural and functional characterization of the leukocyte integrin gene CD11d. Essential role of Sp1 and Sp3.
PubMed ID: 10722744
PubMed ID: 8666289
Title: Cloning and chromosomal localization of a novel gene-encoding a human beta 2-integrin alpha subunit.
PubMed ID: 8666289
PubMed ID: 9841932
Title: Alphadbeta2 integrin is expressed on human eosinophils and functions as an alternative ligand for vascular cell adhesion molecule 1 (VCAM-1).
PubMed ID: 9841932
PubMed ID: 10438935
Title: The leukocyte integrin alpha D beta 2 binds VCAM-1: evidence for a binding interface between I domain and VCAM-1.
PubMed ID: 10438935
Sequence Information:
- Length: 1161
- Mass: 126758
- Checksum: 769D658010CE5823
- Sequence:
MTFGTVLLLS VLASYHGFNL DVEEPTIFQE DAGGFGQSVV QFGGSRLVVG APLEVVAANQ TGRLYDCAAA TGMCQPIPLH IRPEAVNMSL GLTLAASTNG SRLLACGPTL HRVCGENSYS KGSCLLLGSR WEIIQTVPDA TPECPHQEMD IVFLIDGSGS IDQNDFNQMK GFVQAVMGQF EGTDTLFALM QYSNLLKIHF TFTQFRTSPS QQSLVDPIVQ LKGLTFTATG ILTVVTQLFH HKNGARKSAK KILIVITDGQ KYKDPLEYSD VIPQAEKAGI IRYAIGVGHA FQGPTARQEL NTISSAPPQD HVFKVDNFAA LGSIQKQLQE KIYAVEGTQS RASSSFQHEM SQEGFSTALT MDGLFLGAVG SFSWSGGAFL YPPNMSPTFI NMSQENVDMR DSYLGYSTEL ALWKGVQNLV LGAPRYQHTG KAVIFTQVSR QWRKKAEVTG TQIGSYFGAS LCSVDVDSDG STDLILIGAP HYYEQTRGGQ VSVCPLPRGR VQWQCDAVLR GEQGHPWGRF GAALTVLGDV NEDKLIDVAI GAPGEQENRG AVYLFHGASE SGISPSHSQR IASSQLSPRL QYFGQALSGG QDLTQDGLMD LAVGARGQVL LLRSLPVLKV GVAMRFSPVE VAKAVYRCWE EKPSALEAGD ATVCLTIQKS SLDQLGDIQS SVRFDLALDP GRLTSRAIFN ETKNPTLTRR KTLGLGIHCE TLKLLLPDCV EDVVSPIILH LNFSLVREPI PSPQNLRPVL AVGSQDLFTA SLPFEKNCGQ DGLCEGDLGV TLSFSGLQTL TVGSSLELNV IVTVWNAGED SYGTVVSLYY PAGLSHRRVS GAQKQPHQSA LRLACETVPT EDEGLRSSRC SVNHPIFHEG SNGTFIVTFD VSYKATLGDR MLMRASASSE NNKASSSKAT FQLELPVKYA VYTMISRQEE STKYFNFATS DEKKMKEAEH RYRVNNLSQR DLAISINFWV PVLLNGVAVW DVVMEAPSQS LPCVSERKPP QHSDFLTQIS RSPMLDCSIA DCLQFRCDVP SFSVQEELDF TLKGNLSFGW VRETLQKKVL VVSVAEITFD TSVYSQLPGQ EAFMRAQMEM VLEEDEVYNA IPIIMGSSVG ALLLLALITA TLYKLGFFKR HYKEMLEDKP EDTATFSGDD FSCVAPNVPL S
Genular Protein ID: 1221976221
Symbol: Q59H14_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 1177
- Mass: 128451
- Checksum: A7BBC68CE26B49C3
- Sequence:
CALSPTFHFP STRCSGMTFG TVLLLSVLAS YHGFNLDVEE PTIFQEDAGG FGQSVVQFGG SRLVVGAPLE VVAANQTGRL YDCAAATGMC QPIPLHIRPE AVNMSLGLTL AASTNGSRLL ACGPTLHRVC GENSYSKGSC LLLGSRWEII QTVPDATPEC PHQEMDIVFL IDGSGSIDQN DFNQMKGFVQ AVMGQFEGTD TLFALMQYSN LLKIHFTFTQ FRTSPSQQSL VDPIVQLKGL TFTATGILTV VTQLFHHKNG ARKSAKKILI VITDGQKYKD PLEYSDVIPQ AEKAGIIRYA IGVGHAFQGP TARQELNTIS SAPPQDHVFK VDNFAALGSI QKQLQEKIYA VEGTQSRASS SFQHEMSQEG FSTALTMDGL FLGAVGSFSW SGGAFLYPPN MSPTFINMSQ ENVDMRDSYL GYSTELALWK GVQNLVLGAP RYQHTGKAVI FTQVSRQWRK KAEVTGTQIG SYFGASLCSV DVDSDGSTDL ILIGAPHYYE QTRGGQVSVC PLPRGRVQWQ CDAVLRGEQG HPWGRFGAAL TVLGDVNEDK LIDVAIGAPG EQENRGAVYL FHGASESGIS PSHSQRIASS QLSPRLQYFG QALSGGQDLT QDGLMDLAVG ARGQVLLLRS LPVLKVGVAM RFSPVEVAKA VYRCWEEKPS ALEAGDATVC LTIQKSSLDQ LGDIQSSVRF DLALDPGRLT SRAIFNETKN PTLTRRKTLG LGIHCETLKL LLPDCVEDVV SPIILHLNFS LVREPIPSPQ NLRPVLAVGS QDLFTASLPF EKNCGQDGLC EGDLGVTLSF SGLQTLTVGS SLELNVIVTV WNAGEDSYGT VVSLYYPAGL SHRRVSGAQK QPHQSALRLA CETVPTEDEG LRSSRCSVNH PIFHEGSNGT FIVTFDVSYK ATLGDRMLMR ASASSENNKA SSSKATFQLE LPVKYAVYTM ISRQEESTKY FNFATSDEKK MKEAEHRYRV NNLSQRDLAI SINFWVPVLL NGVAVWDVVM EAPSQSLPCV SERKPPQHSD FLTQISRSPM LDCSIADCLQ FRCDVPSFSV QEELDFTLKG NLSFGWVRET LQKKVLVVSV AEITFDTSVY SQLPGQEAFM RAQMEMVLEE DEVYNAIPII MGSSVGALLL LALITATLYK LGFFKRHYKE MLEDKPEDTA TFSGDDFSCV APNVPLS
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.