Details for: OLR1

Gene ID: 4973

Symbol: OLR1

Ensembl ID: ENSG00000173391

Description: oxidized low density lipoprotein receptor 1

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mucosal type mast cell (CL0000485)
    Fold Change: 27.0764
    Cell Significance Index: -11.0000
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 4.8862
    Cell Significance Index: 130.4700
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 4.2685
    Cell Significance Index: 66.0400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: 0.3765
    Cell Significance Index: 79.3000
  • Cell Name: mononuclear cell (CL0000842)
    Fold Change: 0.3748
    Cell Significance Index: 1.5600
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.2571
    Cell Significance Index: 51.0200
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 0.1033
    Cell Significance Index: 1.9100
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.0699
    Cell Significance Index: 0.5700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0554
    Cell Significance Index: 34.6200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0253
    Cell Significance Index: 5.0700
  • Cell Name: mature microglial cell (CL0002629)
    Fold Change: 0.0119
    Cell Significance Index: 0.1300
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0014
    Cell Significance Index: 1.0500
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: 0.0007
    Cell Significance Index: 0.3900
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: 0.0001
    Cell Significance Index: 0.0400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0053
    Cell Significance Index: -9.9500
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0076
    Cell Significance Index: -5.7800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0087
    Cell Significance Index: -13.4200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0090
    Cell Significance Index: -16.5100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0102
    Cell Significance Index: -1.1700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0117
    Cell Significance Index: -1.9900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0123
    Cell Significance Index: -16.6600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0138
    Cell Significance Index: -3.9800
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0155
    Cell Significance Index: -9.8700
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0174
    Cell Significance Index: -1.7800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0206
    Cell Significance Index: -11.2500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0242
    Cell Significance Index: -8.6700
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0261
    Cell Significance Index: -11.8600
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0357
    Cell Significance Index: -6.4300
  • Cell Name: elicited macrophage (CL0000861)
    Fold Change: -0.0389
    Cell Significance Index: -0.3400
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.0390
    Cell Significance Index: -0.3700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0568
    Cell Significance Index: -6.9900
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0598
    Cell Significance Index: -8.6900
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.0676
    Cell Significance Index: -7.7200
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.0772
    Cell Significance Index: -0.6800
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0813
    Cell Significance Index: -9.5900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0817
    Cell Significance Index: -11.2200
  • Cell Name: central nervous system macrophage (CL0000878)
    Fold Change: -0.0849
    Cell Significance Index: -1.0200
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0886
    Cell Significance Index: -3.6300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0889
    Cell Significance Index: -11.4900
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.1025
    Cell Significance Index: -11.9500
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1031
    Cell Significance Index: -10.7400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.1040
    Cell Significance Index: -5.2600
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1088
    Cell Significance Index: -5.1200
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.1272
    Cell Significance Index: -16.3100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.1276
    Cell Significance Index: -3.2800
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1293
    Cell Significance Index: -10.2400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.1306
    Cell Significance Index: -3.6500
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.1384
    Cell Significance Index: -7.1900
  • Cell Name: mononuclear phagocyte (CL0000113)
    Fold Change: -0.1455
    Cell Significance Index: -1.2300
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1527
    Cell Significance Index: -11.3800
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1559
    Cell Significance Index: -10.4800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1675
    Cell Significance Index: -12.8500
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.1741
    Cell Significance Index: -9.0700
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.1888
    Cell Significance Index: -5.0500
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.1902
    Cell Significance Index: -3.2300
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.1947
    Cell Significance Index: -11.9700
  • Cell Name: myeloid cell (CL0000763)
    Fold Change: -0.2069
    Cell Significance Index: -2.7500
  • Cell Name: hematopoietic cell (CL0000988)
    Fold Change: -0.2222
    Cell Significance Index: -3.2500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2437
    Cell Significance Index: -10.7800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.2440
    Cell Significance Index: -13.6900
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2472
    Cell Significance Index: -10.7500
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2571
    Cell Significance Index: -9.0100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2600
    Cell Significance Index: -13.6500
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2696
    Cell Significance Index: -10.2100
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2767
    Cell Significance Index: -12.9000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2804
    Cell Significance Index: -8.9300
  • Cell Name: macrophage (CL0000235)
    Fold Change: -0.2841
    Cell Significance Index: -2.9000
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.2852
    Cell Significance Index: -4.1400
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.3100
    Cell Significance Index: -11.3800
  • Cell Name: immature innate lymphoid cell (CL0001082)
    Fold Change: -0.3145
    Cell Significance Index: -3.8900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.3197
    Cell Significance Index: -20.1500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3202
    Cell Significance Index: -10.4900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.3588
    Cell Significance Index: -10.2400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3592
    Cell Significance Index: -10.5800
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: -0.3684
    Cell Significance Index: -4.3400
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: -0.3910
    Cell Significance Index: -3.1700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.4029
    Cell Significance Index: -11.5500
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.4086
    Cell Significance Index: -12.0000
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.4094
    Cell Significance Index: -10.9700
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.4169
    Cell Significance Index: -10.4000
  • Cell Name: microglial cell (CL0000129)
    Fold Change: -0.4176
    Cell Significance Index: -4.9100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.4233
    Cell Significance Index: -11.1300
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.4261
    Cell Significance Index: -8.6700
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.4299
    Cell Significance Index: -10.7200
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.4478
    Cell Significance Index: -5.8000
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.4562
    Cell Significance Index: -8.9200
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.4710
    Cell Significance Index: -11.4100
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.4785
    Cell Significance Index: -12.1900
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.4824
    Cell Significance Index: -5.4800
  • Cell Name: CD14-positive, CD16-low monocyte (CL0001055)
    Fold Change: -0.4865
    Cell Significance Index: -4.6800
  • Cell Name: CD1c-positive myeloid dendritic cell (CL0002399)
    Fold Change: -0.4866
    Cell Significance Index: -5.0400
  • Cell Name: L5/6 near-projecting glutamatergic neuron (CL4030067)
    Fold Change: -0.4908
    Cell Significance Index: -2.5700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.5017
    Cell Significance Index: -10.8400
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.5076
    Cell Significance Index: -10.8500
  • Cell Name: embryonic fibroblast (CL2000042)
    Fold Change: -0.5080
    Cell Significance Index: -2.4300
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.5112
    Cell Significance Index: -10.6700
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.5136
    Cell Significance Index: -10.9000
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.5258
    Cell Significance Index: -8.8000
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.5267
    Cell Significance Index: -16.6600
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.5298
    Cell Significance Index: -3.5900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** OLR1 is a receptor that recognizes and binds to oxidized low-density lipoproteins (oxLDL), which are modified forms of cholesterol-rich lipoproteins. This interaction triggers a signaling cascade that modulates immune responses, lipid metabolism, and vascular homeostasis. OLR1 is characterized by its ability to: 1. Regulate immune cell function: OLR1 modulates the activity of immune cells, including macrophages, dendritic cells, and microglial cells, influencing their cytokine production, phagocytic activity, and antigen presentation. 2. Influence lipid metabolism: OLR1 regulates the uptake and metabolism of oxLDL, which is essential for maintaining lipid homeostasis and preventing atherosclerosis. 3. Interact with other receptors: OLR1 interacts with other receptors, such as LDLR and SCARB1, to form lipid-transport complexes that regulate cholesterol homeostasis. **Pathways and Functions:** OLR1 is involved in various signaling pathways, including: 1. **Immune response regulation**: OLR1 modulates the activity of immune cells, influencing cytokine production, phagocytic activity, and antigen presentation. 2. **Lipid metabolism**: OLR1 regulates the uptake and metabolism of oxLDL, influencing lipid homeostasis and preventing atherosclerosis. 3. **Vascular homeostasis**: OLR1 maintains vascular health by regulating the uptake and metabolism of oxLDL, which is essential for preventing atherosclerosis and cardiovascular disease. **Clinical Significance:** The dysregulation of OLR1 has been implicated in various immune-related disorders and cardiovascular diseases, including: 1. **Atherosclerosis**: OLR1 dysfunction contributes to the development of atherosclerosis, a condition characterized by the buildup of plaque in the arteries. 2. **Inflammatory diseases**: OLR1 modulates immune responses, which are often dysregulated in inflammatory diseases, such as rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease. 3. **Cardiovascular disease**: OLR1 dysfunction is associated with an increased risk of cardiovascular disease, including heart attacks, strokes, and peripheral artery disease. In conclusion, OLR1 plays a critical role in regulating immune responses, lipid metabolism, and vascular health. Understanding the functions and pathways of OLR1 will provide valuable insights into the development of novel therapeutic strategies for immune-related disorders and cardiovascular diseases. Further research is needed to elucidate the mechanisms by which OLR1 regulates immune responses and lipid metabolism, and to explore its potential as a therapeutic target.

Genular Protein ID: 3653587767

Symbol: OLR1_HUMAN

Name: Oxidized low-density lipoprotein receptor 1

UniProtKB Accession Codes:

P78380 A8K7V9 B4DI48 G3V1I4 Q2PP00 Q7Z484

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 16 Ensembl 3 EvolutionaryTrace 1 ExpressionAtlas 1 GO 18 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 NIAGADS 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 12 PDBsum 12 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 3 RNAct 1 Reactome 2 RefSeq 3 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 9052782

Title: An endothelial receptor for oxidized low-density lipoprotein.

PubMed ID: 9052782

DOI: 10.1038/386073a0

PubMed ID: 9763655

Title: Assignment of the human oxidized low-density lipoprotein receptor gene (OLR1) to chromosome 12p13.1-->p12.3, and identification of a polymorphic CA-repeat marker in the OLR1 gene.

PubMed ID: 9763655

DOI: 10.1159/000015059

PubMed ID: 11256994

Title: Characterization of residues and sequences of the carbohydrate recognition domain required for cell surface localization and ligand binding of human lectin-like oxidized LDL receptor.

PubMed ID: 11256994

DOI: 10.1242/jcs.114.7.1273

PubMed ID: 9828121

Title: The human gene encoding the lectin-type oxidized LDL receptor (OLR1) is a novel member of the natural killer gene complex with a unique expression profile.

PubMed ID: 9828121

DOI: 10.1006/geno.1998.5561

PubMed ID: 12646194

Title: Oxidized LDL receptor gene (OLR1) is associated with the risk of myocardial infarction.

PubMed ID: 12646194

DOI: 10.1016/s0006-291x(03)00326-7

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16541075

Title: The finished DNA sequence of human chromosome 12.

PubMed ID: 16541075

DOI: 10.1038/nature04569

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 11821063

Title: Lectin-like oxidized LDL receptor-1 (LOX-1) supports adhesion of mononuclear leukocytes and a monocyte-like cell line THP-1 cells under static and flow conditions.

PubMed ID: 11821063

DOI: 10.1016/s0014-5793(01)03297-5

PubMed ID: 12354387

Title: Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation.

PubMed ID: 12354387

DOI: 10.1016/s1074-7613(02)00388-6

PubMed ID: 12384789

Title: Investigation of oxidized LDL-receptor 1 (OLR1) as the candidate gene for Alzheimer's disease on chromosome 12.

PubMed ID: 12384789

DOI: 10.1007/s00439-002-0802-7

PubMed ID: 12878212

Title: Oxidized LDL through LOX-1 modulates LDL-receptor expression in human coronary artery endothelial cells.

PubMed ID: 12878212

DOI: 10.1016/s0006-291x(03)01295-6

PubMed ID: 12810610

Title: Genetic variation in lectin-like oxidized low-density lipoprotein receptor 1 (LOX1) gene and the risk of coronary artery disease.

PubMed ID: 12810610

DOI: 10.1161/01.cir.0000074207.85796.36

PubMed ID: 12807963

Title: Association of 3'-UTR polymorphisms of the oxidised LDL receptor 1 (OLR1) gene with Alzheimer's disease.

PubMed ID: 12807963

DOI: 10.1136/jmg.40.6.424

PubMed ID: 15000751

Title: Human lectin-like oxidized low-density lipoprotein receptor-1 functions as a dimer in living cells.

PubMed ID: 15000751

DOI: 10.1089/104454904322759920

PubMed ID: 15060104

Title: No association between a previously reported OLR1 3' UTR polymorphism and Alzheimer's disease in a large family sample.

PubMed ID: 15060104

DOI: 10.1136/jmg.2003.016980

PubMed ID: 15276231

Title: No association between polymorphisms in the lectin-like oxidised low density lipoprotein receptor (ORL1) gene on chromosome 12 and Alzheimer's disease in a UK cohort.

PubMed ID: 15276231

DOI: 10.1016/j.neulet.2004.05.023

PubMed ID: 15976314

Title: In vivo and in vitro studies support that a new splicing isoform of OLR1 gene is protective against acute myocardial infarction.

PubMed ID: 15976314

DOI: 10.1161/01.res.0000174563.62625.8e

PubMed ID: 15860461

Title: Polymorphisms in the oxidized low-density lipoprotein receptor-1 gene and risk of Alzheimer's disease.

PubMed ID: 15860461

DOI: 10.1093/gerona/60.3.280

PubMed ID: 15935375

Title: Essential role of cytoplasmic sequences for cell-surface sorting of the lectin-like oxidized LDL receptor-1 (LOX-1).

PubMed ID: 15935375

DOI: 10.1016/j.yjmcc.2005.05.001

PubMed ID: 22688517

Title: Site-specific N-glycosylation identification of recombinant human lectin-like oxidized low density lipoprotein receptor-1 (LOX-1).

PubMed ID: 22688517

DOI: 10.1007/s10719-012-9408-z

PubMed ID: 23583401

Title: Lectin-like oxidized LDL receptor-1 is palmitoylated and internalizes ligands via caveolae/raft-dependent endocytosis.

PubMed ID: 23583401

DOI: 10.1016/j.bbrc.2013.03.120

PubMed ID: 27302108

Title: Exploring host-pathogen interactions through genome wide protein microarray analysis.

PubMed ID: 27302108

DOI: 10.1038/srep27996

PubMed ID: 30327444

Title: NadA3 Structures Reveal Undecad Coiled Coils and LOX1 Binding Regions Competed by Meningococcus B Vaccine-Elicited Human Antibodies.

PubMed ID: 30327444

DOI: 10.1128/mbio.01914-18

PubMed ID: 15695803

Title: The 1.4 angstrom crystal structure of the human oxidized low density lipoprotein receptor lox-1.

PubMed ID: 15695803

DOI: 10.1074/jbc.m500768200

PubMed ID: 15939022

Title: Crystal structure of human lectin-like, oxidized low-density lipoprotein receptor 1 ligand binding domain and its ligand recognition mode to oxLDL.

PubMed ID: 15939022

DOI: 10.1016/j.str.2005.03.016

Sequence Information:

  • Length: 273
  • Mass: 30959
  • Checksum: 852DE6595DC3D361
  • Sequence:
    • MTFDDLKIQT VKDQPDEKSN GKKAKGLQFL YSPWWCLAAA TLGVLCLGLV VTIMVLGMQL 
SQVSDLLTQE QANLTHQKKK LEGQISARQQ AEEASQESEN ELKEMIETLA RKLNEKSKEQ 
MELHHQNLNL QETLKRVANC SAPCPQDWIW HGENCYLFSS GSFNWEKSQE KCLSLDAKLL 
KINSTADLDF IQQAISYSSF PFWMGLSRRN PSYPWLWEDG SPLMPHLFRV RGAVSQTYPS 
GTCAYIQRGA VYAENCILAA FSICQKKANL RAQ

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.