Details for: DUOX2

Gene ID: 50506

Symbol: DUOX2

Ensembl ID: ENSG00000140279

Description: dual oxidase 2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 9.9817
    Cell Significance Index: 518.5200
  • Cell Name: thyroid follicular cell (CL0002258)
    Fold Change: 4.2316
    Cell Significance Index: 44.9600
  • Cell Name: ciliated cell of the bronchus (CL0002332)
    Fold Change: 3.4355
    Cell Significance Index: -3.2800
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 2.5638
    Cell Significance Index: 34.9800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: 2.4953
    Cell Significance Index: 152.9900
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 1.7337
    Cell Significance Index: 37.5600
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 1.5156
    Cell Significance Index: -4.0600
  • Cell Name: epithelial cell of prostate (CL0002231)
    Fold Change: 1.1970
    Cell Significance Index: 7.3900
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 1.0143
    Cell Significance Index: 32.4900
  • Cell Name: epithelial cell of esophagus (CL0002252)
    Fold Change: 0.6357
    Cell Significance Index: 4.2200
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5042
    Cell Significance Index: 49.8800
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.4752
    Cell Significance Index: 7.8300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.4337
    Cell Significance Index: 78.1800
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4107
    Cell Significance Index: 370.8300
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: 0.4101
    Cell Significance Index: 47.7900
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 0.4012
    Cell Significance Index: 8.5500
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: 0.3833
    Cell Significance Index: 3.5300
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.2614
    Cell Significance Index: 28.4300
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.2604
    Cell Significance Index: 42.3500
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: 0.2076
    Cell Significance Index: 1.2900
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.2065
    Cell Significance Index: 12.4000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1899
    Cell Significance Index: 23.3600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.1762
    Cell Significance Index: 4.7200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.1367
    Cell Significance Index: 9.4600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1058
    Cell Significance Index: 20.1300
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0996
    Cell Significance Index: 2.7800
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: 0.0859
    Cell Significance Index: 9.8000
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: 0.0759
    Cell Significance Index: 1.0800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.0482
    Cell Significance Index: 0.6900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.0408
    Cell Significance Index: 1.1100
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0302
    Cell Significance Index: 1.3700
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 0.0261
    Cell Significance Index: 0.1700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.0226
    Cell Significance Index: 0.6500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0184
    Cell Significance Index: 3.1500
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.0149
    Cell Significance Index: 6.6000
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.0131
    Cell Significance Index: 0.6600
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 0.0101
    Cell Significance Index: 0.1400
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0067
    Cell Significance Index: 4.6300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0065
    Cell Significance Index: 0.2300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: 0.0037
    Cell Significance Index: 2.2900
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: 0.0025
    Cell Significance Index: 0.2900
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0024
    Cell Significance Index: 0.0600
  • Cell Name: tracheal goblet cell (CL1000329)
    Fold Change: 0.0024
    Cell Significance Index: 0.0200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0009
    Cell Significance Index: -0.6900
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0012
    Cell Significance Index: -2.2400
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0018
    Cell Significance Index: -3.2800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0019
    Cell Significance Index: -1.0300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0020
    Cell Significance Index: -1.1000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0024
    Cell Significance Index: -3.6400
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0026
    Cell Significance Index: -0.7400
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0029
    Cell Significance Index: -2.2100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0029
    Cell Significance Index: -3.9200
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0037
    Cell Significance Index: -2.3800
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0053
    Cell Significance Index: -0.6800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0057
    Cell Significance Index: -1.2100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0060
    Cell Significance Index: -2.1600
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0074
    Cell Significance Index: -1.4900
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0085
    Cell Significance Index: -3.8700
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: -0.0087
    Cell Significance Index: -1.7200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0089
    Cell Significance Index: -1.2900
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0096
    Cell Significance Index: -0.2000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0231
    Cell Significance Index: -3.1700
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0241
    Cell Significance Index: -0.9900
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.0280
    Cell Significance Index: -1.9800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0307
    Cell Significance Index: -3.9700
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0326
    Cell Significance Index: -3.3900
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0337
    Cell Significance Index: -0.8700
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.0343
    Cell Significance Index: -4.0500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0349
    Cell Significance Index: -3.5600
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0380
    Cell Significance Index: -1.7700
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0386
    Cell Significance Index: -0.9700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0454
    Cell Significance Index: -3.0500
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0510
    Cell Significance Index: -3.8000
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0534
    Cell Significance Index: -4.1000
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0589
    Cell Significance Index: -0.9900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0615
    Cell Significance Index: -3.9700
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: -0.0634
    Cell Significance Index: -3.3000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0717
    Cell Significance Index: -3.1700
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0749
    Cell Significance Index: -3.5200
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0759
    Cell Significance Index: -4.2600
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: -0.0768
    Cell Significance Index: -0.8100
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0818
    Cell Significance Index: -2.4100
  • Cell Name: intestinal crypt stem cell (CL0002250)
    Fold Change: -0.0824
    Cell Significance Index: -0.5800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0824
    Cell Significance Index: -3.1200
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0834
    Cell Significance Index: -3.0600
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.0836
    Cell Significance Index: -1.2600
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0928
    Cell Significance Index: -4.8700
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0942
    Cell Significance Index: -3.3000
  • Cell Name: M cell of gut (CL0000682)
    Fold Change: -0.0960
    Cell Significance Index: -0.8000
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.1000
    Cell Significance Index: -1.6200
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.1005
    Cell Significance Index: -3.2900
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.1027
    Cell Significance Index: -3.2700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: -0.1043
    Cell Significance Index: -1.1900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1049
    Cell Significance Index: -3.6500
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.1093
    Cell Significance Index: -3.1200
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.1103
    Cell Significance Index: -2.9000
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.1112
    Cell Significance Index: -1.5000
  • Cell Name: epidermal cell (CL0000362)
    Fold Change: -0.1114
    Cell Significance Index: -0.2500
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.1185
    Cell Significance Index: -1.8800
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.1193
    Cell Significance Index: -3.0400

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** DUOX2 is a dual oxidase enzyme that generates H2O2 through the reduction of oxygen by NADPH. The enzyme consists of two subunits, DUOX2A and DUOX2B, which interact to produce the reactive oxygen species. DUOX2 is characterized by its ability to regulate the production of H2O2, which is essential for immune defense, cell signaling, and metabolic regulation. The enzyme is also involved in the regulation of various cellular processes, including cell motility, wound healing, and the response to oxidative stress. **Pathways and Functions:** DUOX2 is involved in several key pathways, including: 1. **Immune Defense:** DUOX2 plays a crucial role in the innate immune response, particularly in the production of H2O2, which is essential for killing pathogens and activating immune cells. 2. **Cell Signaling:** DUOX2 regulates various cellular signaling pathways, including those involved in cell motility, wound healing, and the response to oxidative stress. 3. **Metabolic Regulation:** DUOX2 is involved in the regulation of metabolic processes, including the metabolism of amino acids and derivatives, thyroid hormone generation, and the biosynthesis of amine-derived hormones. 4. **Oxidative Stress Response:** DUOX2 is activated in response to oxidative stress, and its activity helps to regulate the production of ROS and mitigate oxidative damage. **Clinical Significance:** DUOX2 has been implicated in various diseases and disorders, including: 1. **Thyroid Disorders:** DUOX2 deficiency has been linked to thyroid disorders, such as hypothyroidism and goiter. 2. **Respiratory Diseases:** DUOX2 has been implicated in the pathogenesis of respiratory diseases, such as chronic obstructive pulmonary disease (COPD) and asthma. 3. **Cancer:** DUOX2 has been found to be overexpressed in certain types of cancer, including prostate cancer and breast cancer. 4. **Neurological Disorders:** DUOX2 has been implicated in the pathogenesis of neurological disorders, such as Alzheimer's disease and Parkinson's disease. In conclusion, DUOX2 is a critical gene involved in immune defense, metabolic regulation, and the response to oxidative stress. Its dysregulation has been implicated in various diseases and disorders, highlighting the importance of DUOX2 in maintaining human health. Further research is needed to fully elucidate the role of DUOX2 in human disease and to explore potential therapeutic strategies for the treatment of DUOX2-related disorders.

Genular Protein ID: 1843968870

Symbol: DUOX2_HUMAN

Name: Dual oxidase 2

UniProtKB Accession Codes:

Q9NRD8 A8MQ13 D2XI64 Q9NR02 Q9UHF9

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 3 CTD 1 ChEBI 19 ChiTaRS 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 EC 4 EMBL 5 Ensembl 1 ExpressionAtlas 1 GO 30 Gene3D 4 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 GlyCosmos 1 GlyGen 1 GuidetoPHARMACOLOGY 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 14 KEGG 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OpenTargets 1 Orphanet 2 OrthoDB 1 PANTHER 2 PRINTS 1 PRO 1 PROSITE 4 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 PeroxiBase 1 Pfam 6 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 1 RefSeq 1 Rhea 2 SABIO-RK 1 SFLD 3 SIGNOR 1 SMART 1 SMR 1 STRING 1 SUPFAM 4 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 UniPathway 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 10806195

Title: Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family.

PubMed ID: 10806195

DOI: 10.1074/jbc.m000916200

PubMed ID: 11514595

Title: Tyrosine cross-linking of extracellular matrix is catalyzed by Duox, a multidomain oxidase/peroxidase with homology to the phagocyte oxidase subunit gp91phox.

PubMed ID: 11514595

DOI: 10.1083/jcb.200103132

PubMed ID: 16572171

Title: Analysis of the DNA sequence and duplication history of human chromosome 15.

PubMed ID: 16572171

DOI: 10.1038/nature04601

PubMed ID: 10601291

Title: Purification of a novel flavoprotein involved in the thyroid NADPH oxidase. Cloning of the porcine and human cDNAs.

PubMed ID: 10601291

DOI: 10.1074/jbc.274.52.37265

PubMed ID: 20187165

Title: Compound heterozygosity for a novel hemizygous missense mutation and a partial deletion affecting the catalytic core of the H2O2-generating enzyme DUOX2 associated with transient congenital hypothyroidism.

PubMed ID: 20187165

DOI: 10.1002/humu.21227

PubMed ID: 11822874

Title: Characterization of ThOX proteins as components of the thyroid H(2)O(2)-generating system.

PubMed ID: 11822874

DOI: 10.1006/excr.2001.5444

PubMed ID: 12110737

Title: Inactivating mutations in the gene for thyroid oxidase 2 (THOX2) and congenital hypothyroidism.

PubMed ID: 12110737

DOI: 10.1056/nejmoa012752

PubMed ID: 12824283

Title: Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense.

PubMed ID: 12824283

DOI: 10.1096/fj.02-1104fje

PubMed ID: 15210697

Title: NADPH oxidase-dependent acid production in airway epithelial cells.

PubMed ID: 15210697

DOI: 10.1074/jbc.m404983200

PubMed ID: 15591162

Title: Dual oxidase2 is expressed all along the digestive tract.

PubMed ID: 15591162

DOI: 10.1152/ajpgi.00198.2004

PubMed ID: 15561711

Title: Identification of a novel partner of duox: EFP1, a thioredoxin-related protein.

PubMed ID: 15561711

DOI: 10.1074/jbc.m407709200

PubMed ID: 15972824

Title: Dual oxidase-2 has an intrinsic Ca2+-dependent H2O2-generating activity.

PubMed ID: 15972824

DOI: 10.1074/jbc.m500516200

PubMed ID: 16134168

Title: Persistent mild hypothyroidism associated with novel sequence variants of the DUOX2 gene in two siblings.

PubMed ID: 16134168

DOI: 10.1002/humu.9372

PubMed ID: 16322276

Title: Three mutations (p.Q36H, p.G418fsX482, and g.IVS19-2A-->C) in the dual oxidase 2 gene responsible for congenital goiter and iodide organification defect.

PubMed ID: 16322276

DOI: 10.1373/clinchem.2005.058321

PubMed ID: 25761904

Title: When an intramolecular disulfide bridge governs the interaction of DUOX2 with its partner DUOXA2.

PubMed ID: 25761904

DOI: 10.1089/ars.2015.6265

PubMed ID: 26301257

Title: Defects in NADPH oxidase genes NOX1 and DUOX2 in very early onset inflammatory bowel disease.

PubMed ID: 26301257

DOI: 10.1016/j.jcmgh.2015.06.005

Sequence Information:

  • Length: 1548
  • Mass: 175364
  • Checksum: 7BAA2350EC0A2A7E
  • Sequence:
    • MLRARPEALM LLGALLTGSL GPSGNQDALS LPWEVQRYDG WFNNLRHHER GAVGCRLQRR 
VPANYADGVY QALEEPQLPN PRRLSNAATR GIAGLPSLHN RTVLGVFFGY HVLSDVVSVE 
TPGCPAEFLN IRIPPGDPVF DPDQRGDVVL PFQRSRWDPE TGRSPSNPRD LANQVTGWLD 
GSAIYGSSHS WSDALRSFSG GQLASGPDPA FPRDSQNPLL MWAAPDPATG QNGPRGLYAF 
GAERGNREPF LQALGLLWFR YHNLWAQRLA RQHPDWEDEE LFQHARKRVI ATYQNIAVYE 
WLPSFLQKTL PEYTGYRPFL DPSISPEFVV ASEQFFSTMV PPGVYMRNAS CHFRKVLNKG 
FQSSQALRVC NNYWIRENPN LNSTQEVNEL LLGMASQISE LEDNIVVEDL RDYWPGPGKF 
SRTDYVASSI QRGRDMGLPS YSQALLAFGL DIPRNWSDLN PNVDPQVLEA TAALYNQDLS 
QLELLLGGLL ESHGDPGPLF SAIVLDQFVR LRDGDRYWFE NTRNGLFSKK EIEDIRNTTL 
RDVLVAVINI DPSALQPNVF VWHKGAPCPQ PKQLTTDGLP QCAPLTVLDF FEGSSPGFAI 
TIIALCCLPL VSLLLSGVVA YFRGREHKKL QKKLKESVKK EAAKDGVPAM EWPGPKERSS 
PIIIQLLSDR CLQVLNRHLT VLRVVQLQPL QQVNLILSNN RGCRTLLLKI PKEYDLVLLF 
SSEEERGAFV QQLWDFCVRW ALGLHVAEMS EKELFRKAVT KQQRERILEI FFRHLFAQVL 
DINQADAGTL PLDSSQKVRE ALTCELSRAE FAESLGLKPQ DMFVESMFSL ADKDGNGYLS 
FREFLDILVV FMKGSPEDKS RLMFTMYDLD ENGFLSKDEF FTMMRSFIEI SNNCLSKAQL 
AEVVESMFRE SGFQDKEELT WEDFHFMLRD HDSELRFTQL CVKGGGGGGN GIRDIFKQNI 
SCRVSFITRT PGERSHPQGL GPPAPEAPEL GGPGLKKRFG KKAAVPTPRL YTEALQEKMQ 
RGFLAQKLQQ YKRFVENYRR HIVCVAIFSA ICVGVFADRA YYYGFASPPS DIAQTTLVGI 
ILSRGTAASV SFMFSYILLT MCRNLITFLR ETFLNRYVPF DAAVDFHRWI AMAAVVLAIL 
HSAGHAVNVY IFSVSPLSLL ACIFPNVFVN DGSKLPQKFY WWFFQTVPGM TGVLLLLVLA 
IMYVFASHHF RRRSFRGFWL THHLYILLYA LLIIHGSYAL IQLPTFHIYF LVPAIIYGGD 
KLVSLSRKKV EISVVKAELL PSGVTYLQFQ RPQGFEYKSG QWVRIACLAL GTTEYHPFTL 
TSAPHEDTLS LHIRAVGPWT TRLREIYSSP KGNGCAGYPK LYLDGPFGEG HQEWHKFEVS 
VLVGGGIGVT PFASILKDLV FKSSLGSQML CKKIYFIWVT RTQRQFEWLA DIIQEVEEND 
HQDLVSVHIY VTQLAEKFDL RTTMLYICER HFQKVLNRSL FTGLRSITHF GRPPFEPFFN 
SLQEVHPQVR KIGVFSCGPP GMTKNVEKAC QLVNRQDRAH FMHHYENF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.