Details for: RGPD4 AS1

Gene ID: 729121

Symbol: RGPD4 AS1

Ensembl ID: ENSG00000230651

Description: RGPD4 antisense RNA 1 (head to head)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: mature alpha-beta T cell (CL0000791)
    Fold Change: 2.5711
    Cell Significance Index: 14.0200
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.5576
    Cell Significance Index: 8.1300
  • Cell Name: keratocyte (CL0002363)
    Fold Change: 0.1778
    Cell Significance Index: 2.8200
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: 0.1707
    Cell Significance Index: 4.1400
  • Cell Name: epithelial cell of lacrimal sac (CL1000436)
    Fold Change: 0.1098
    Cell Significance Index: 0.7900
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.0902
    Cell Significance Index: 1.5200
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.0762
    Cell Significance Index: 1.0700
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: 0.0750
    Cell Significance Index: 0.9100
  • Cell Name: squamous epithelial cell (CL0000076)
    Fold Change: 0.0740
    Cell Significance Index: 0.9000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0697
    Cell Significance Index: 4.3900
  • Cell Name: late promyelocyte (CL0002151)
    Fold Change: 0.0482
    Cell Significance Index: 0.3200
  • Cell Name: paneth cell of colon (CL0009009)
    Fold Change: 0.0327
    Cell Significance Index: 0.4900
  • Cell Name: taste receptor cell (CL0000209)
    Fold Change: 0.0318
    Cell Significance Index: 0.3700
  • Cell Name: promonocyte (CL0000559)
    Fold Change: 0.0262
    Cell Significance Index: 0.2800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0234
    Cell Significance Index: 1.0600
  • Cell Name: proerythroblast (CL0000547)
    Fold Change: 0.0070
    Cell Significance Index: 0.1000
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: 0.0044
    Cell Significance Index: 0.0600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0030
    Cell Significance Index: 1.0900
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0006
    Cell Significance Index: 0.1200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0002
    Cell Significance Index: 0.0500
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0001
    Cell Significance Index: -0.2200
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0006
    Cell Significance Index: -1.0500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0006
    Cell Significance Index: -0.8600
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0008
    Cell Significance Index: -0.6100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0008
    Cell Significance Index: -1.0700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0009
    Cell Significance Index: -0.2500
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0010
    Cell Significance Index: -0.6200
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0010
    Cell Significance Index: -0.7600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0010
    Cell Significance Index: -0.7500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0010
    Cell Significance Index: -0.5400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0011
    Cell Significance Index: -0.6000
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0016
    Cell Significance Index: -0.7400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0018
    Cell Significance Index: -0.3000
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0022
    Cell Significance Index: -0.2600
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: -0.0022
    Cell Significance Index: -0.0300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0027
    Cell Significance Index: -0.3900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0027
    Cell Significance Index: -0.0500
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0030
    Cell Significance Index: -0.6300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0032
    Cell Significance Index: -0.5800
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0033
    Cell Significance Index: -0.3800
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0041
    Cell Significance Index: -0.5600
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0046
    Cell Significance Index: -0.0600
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0057
    Cell Significance Index: -0.7000
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.0059
    Cell Significance Index: -0.2500
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0067
    Cell Significance Index: -0.6900
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0072
    Cell Significance Index: -0.9300
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0080
    Cell Significance Index: -0.3300
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0082
    Cell Significance Index: -0.4100
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0083
    Cell Significance Index: -0.2900
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0084
    Cell Significance Index: -0.2300
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: -0.0090
    Cell Significance Index: -0.0900
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0091
    Cell Significance Index: -0.5900
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0091
    Cell Significance Index: -0.5600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0094
    Cell Significance Index: -0.7200
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0095
    Cell Significance Index: -0.6400
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.0103
    Cell Significance Index: -0.1400
  • Cell Name: L4 intratelencephalic projecting glutamatergic neuron (CL4030063)
    Fold Change: -0.0109
    Cell Significance Index: -0.1200
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: -0.0110
    Cell Significance Index: -0.0900
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.0120
    Cell Significance Index: -0.9000
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0122
    Cell Significance Index: -0.1800
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0135
    Cell Significance Index: -0.7600
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0137
    Cell Significance Index: -0.2300
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0147
    Cell Significance Index: -0.4800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0148
    Cell Significance Index: -0.6900
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0151
    Cell Significance Index: -0.6700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0153
    Cell Significance Index: -0.3200
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0160
    Cell Significance Index: -0.4000
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0163
    Cell Significance Index: -0.4800
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0167
    Cell Significance Index: -0.3600
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0169
    Cell Significance Index: -0.6400
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0170
    Cell Significance Index: -0.5400
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0171
    Cell Significance Index: -0.6000
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0173
    Cell Significance Index: -0.2400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0177
    Cell Significance Index: -0.8300
  • Cell Name: vascular leptomeningeal cell (CL4023051)
    Fold Change: -0.0180
    Cell Significance Index: -0.2700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0180
    Cell Significance Index: -0.5200
  • Cell Name: chondrocyte (CL0000138)
    Fold Change: -0.0182
    Cell Significance Index: -0.2100
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0184
    Cell Significance Index: -0.4600
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0198
    Cell Significance Index: -0.5100
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0198
    Cell Significance Index: -0.4100
  • Cell Name: smooth muscle cell of prostate (CL1000487)
    Fold Change: -0.0207
    Cell Significance Index: -0.2400
  • Cell Name: epithelial cell of urethra (CL1000296)
    Fold Change: -0.0210
    Cell Significance Index: -0.1300
  • Cell Name: unswitched memory B cell (CL0000970)
    Fold Change: -0.0213
    Cell Significance Index: -0.1900
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0224
    Cell Significance Index: -0.7800
  • Cell Name: pulmonary capillary endothelial cell (CL4028001)
    Fold Change: -0.0226
    Cell Significance Index: -0.3100
  • Cell Name: CD8-positive, alpha-beta thymocyte (CL0000811)
    Fold Change: -0.0227
    Cell Significance Index: -0.2100
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: -0.0229
    Cell Significance Index: -0.2500
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0234
    Cell Significance Index: -0.4700
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0238
    Cell Significance Index: -0.4100
  • Cell Name: lung macrophage (CL1001603)
    Fold Change: -0.0238
    Cell Significance Index: -0.2600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0239
    Cell Significance Index: -0.6400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0240
    Cell Significance Index: -0.5100
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0243
    Cell Significance Index: -0.6500
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0248
    Cell Significance Index: -0.4900
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0249
    Cell Significance Index: -0.7100
  • Cell Name: adventitial cell (CL0002503)
    Fold Change: -0.0252
    Cell Significance Index: -0.2300
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: -0.0253
    Cell Significance Index: -0.2500
  • Cell Name: fibroblast of connective tissue of glandular part of prostate (CL1000305)
    Fold Change: -0.0253
    Cell Significance Index: -0.2800
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0254
    Cell Significance Index: -0.6800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** 1. **Antisense RNA expression**: RGPD4 AS1 is a non-coding RNA transcript that is transcribed in the opposite direction to the RGPD4 gene, a characteristic shared by other antisense RNAs. 2. **Widespread expression**: RGPD4 AS1 is significantly expressed in multiple cell types, including immune cells, epithelial cells, and stem cells. 3. **Head-to-head orientation**: The RGPD4 AS1 transcript is oriented head-to-head with the RGPD4 gene, suggesting a regulatory relationship between these two transcripts. 4. **Cell-type specificity**: RGPD4 AS1 expression is cell-type specific, with distinct patterns of expression observed in different cell types. **Pathways and Functions** 1. **Immune regulation**: RGPD4 AS1 may play a role in regulating immune responses, particularly in the context of inflammation and immune cell activation. 2. **Cellular differentiation**: RGPD4 AS1 may contribute to the regulation of cellular differentiation, particularly in the context of immune cell development and function. 3. **Stem cell maintenance**: RGPD4 AS1 may play a role in maintaining the stem cell compartment, particularly in the context of intestinal crypt stem cells. 4. **Gene regulation**: RGPD4 AS1 may act as a regulator of gene expression, potentially influencing the expression of other genes involved in immune response and cellular differentiation. **Clinical Significance** 1. **Inflammation and immune response**: RGPD4 AS1 may play a role in regulating immune responses, particularly in the context of inflammatory diseases such as atherosclerosis and autoimmune disorders. 2. **Cancer development**: RGPD4 AS1 expression has been observed in various types of cancer, suggesting a potential role in cancer development and progression. 3. **Neurological disorders**: RGPD4 AS1 expression has been observed in the cerebral cortex and forebrain, suggesting a potential role in neurological disorders such as Alzheimer's disease and Parkinson's disease. 4. **Regulatory RNAs**: RGPD4 AS1 may serve as a model for studying the functional significance of regulatory RNAs in various cellular processes. In conclusion, RGPD4 AS1 is a complex and multifunctional gene that plays a critical role in regulating immune responses, cellular differentiation, and stem cell maintenance. Further studies are needed to fully elucidate the functional significance of RGPD4 AS1 and its potential applications in the diagnosis and treatment of various diseases.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.