Details for: INKA2 AS1

Gene ID: 100506343

Symbol: INKA2 AS1

Ensembl ID: ENSG00000227811

Description: INKA2 antisense RNA 1

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 1.4861
    Cell Significance Index: 7.8200
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 1.1372
    Cell Significance Index: 16.5800
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.2270
    Cell Significance Index: 3.7400
  • Cell Name: perivascular cell (CL4033054)
    Fold Change: 0.1689
    Cell Significance Index: 0.7800
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 0.1612
    Cell Significance Index: 1.3700
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.1265
    Cell Significance Index: 7.9700
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.1175
    Cell Significance Index: 22.3700
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 0.0938
    Cell Significance Index: 0.6100
  • Cell Name: primitive red blood cell (CL0002355)
    Fold Change: 0.0830
    Cell Significance Index: 0.9400
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0646
    Cell Significance Index: 2.9300
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0613
    Cell Significance Index: 1.0500
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0576
    Cell Significance Index: 11.5500
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0247
    Cell Significance Index: 7.1000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0199
    Cell Significance Index: 3.5900
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 0.0176
    Cell Significance Index: 0.2400
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0144
    Cell Significance Index: 5.1700
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0028
    Cell Significance Index: 0.4700
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.0019
    Cell Significance Index: 0.0200
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0006
    Cell Significance Index: -1.1700
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0011
    Cell Significance Index: -2.0900
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0016
    Cell Significance Index: -2.5200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0025
    Cell Significance Index: -3.3800
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0030
    Cell Significance Index: -1.6700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0033
    Cell Significance Index: -2.4200
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0033
    Cell Significance Index: -0.3900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0034
    Cell Significance Index: -2.6100
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0034
    Cell Significance Index: -0.4300
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0035
    Cell Significance Index: -2.2000
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0035
    Cell Significance Index: -1.9300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0042
    Cell Significance Index: -0.3300
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0045
    Cell Significance Index: -2.8400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0051
    Cell Significance Index: -2.3000
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0061
    Cell Significance Index: -0.8400
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0064
    Cell Significance Index: -0.3300
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0073
    Cell Significance Index: -0.1600
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0080
    Cell Significance Index: -0.9200
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0084
    Cell Significance Index: -1.2200
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: -0.0096
    Cell Significance Index: -0.1200
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0120
    Cell Significance Index: -0.7400
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0127
    Cell Significance Index: -2.6900
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0129
    Cell Significance Index: -1.5900
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0161
    Cell Significance Index: -1.6400
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0194
    Cell Significance Index: -1.0100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.0202
    Cell Significance Index: -1.0600
  • Cell Name: cell of skeletal muscle (CL0000188)
    Fold Change: -0.0219
    Cell Significance Index: -0.2800
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.0221
    Cell Significance Index: -0.3500
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0233
    Cell Significance Index: -0.3900
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: -0.0237
    Cell Significance Index: -0.2500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0247
    Cell Significance Index: -1.0100
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0263
    Cell Significance Index: -2.7400
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0271
    Cell Significance Index: -1.5200
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0307
    Cell Significance Index: -0.6000
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0312
    Cell Significance Index: -1.3800
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0320
    Cell Significance Index: -0.8700
  • Cell Name: large intestine goblet cell (CL1000320)
    Fold Change: -0.0397
    Cell Significance Index: -0.4300
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0426
    Cell Significance Index: -2.0000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0428
    Cell Significance Index: -1.5000
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: -0.0468
    Cell Significance Index: -0.9500
  • Cell Name: myometrial cell (CL0002366)
    Fold Change: -0.0469
    Cell Significance Index: -0.5400
  • Cell Name: radial glial cell (CL0000681)
    Fold Change: -0.0472
    Cell Significance Index: -0.2800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0516
    Cell Significance Index: -1.9600
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0530
    Cell Significance Index: -1.4200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.0541
    Cell Significance Index: -1.8800
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0543
    Cell Significance Index: -1.3200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0549
    Cell Significance Index: -2.5600
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0605
    Cell Significance Index: -3.7100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0609
    Cell Significance Index: -1.9400
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0638
    Cell Significance Index: -2.0900
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.0657
    Cell Significance Index: -0.8200
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0710
    Cell Significance Index: -2.0400
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0716
    Cell Significance Index: -1.4000
  • Cell Name: neuron (CL0000540)
    Fold Change: -0.0728
    Cell Significance Index: -0.6900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.0733
    Cell Significance Index: -2.1600
  • Cell Name: decidual cell (CL2000002)
    Fold Change: -0.0767
    Cell Significance Index: -1.2300
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.0779
    Cell Significance Index: -1.1500
  • Cell Name: cortical thymic epithelial cell (CL0002364)
    Fold Change: -0.0810
    Cell Significance Index: -0.6700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.0813
    Cell Significance Index: -1.3700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0820
    Cell Significance Index: -2.1900
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0846
    Cell Significance Index: -2.1100
  • Cell Name: cerebral cortex neuron (CL0010012)
    Fold Change: -0.0862
    Cell Significance Index: -0.8200
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0872
    Cell Significance Index: -1.8200
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.0888
    Cell Significance Index: -1.5300
  • Cell Name: cortical interneuron (CL0008031)
    Fold Change: -0.0892
    Cell Significance Index: -2.1400
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0907
    Cell Significance Index: -1.9600
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0909
    Cell Significance Index: -2.6200
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0919
    Cell Significance Index: -2.7000
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0932
    Cell Significance Index: -2.3800
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0973
    Cell Significance Index: -2.4800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0988
    Cell Significance Index: -2.0500
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.0997
    Cell Significance Index: -2.4900
  • Cell Name: neuron associated cell (sensu Vertebrata) (CL0000123)
    Fold Change: -0.1004
    Cell Significance Index: -1.1200
  • Cell Name: cardiac muscle cell (CL0000746)
    Fold Change: -0.1009
    Cell Significance Index: -1.4900
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: -0.1015
    Cell Significance Index: -1.2000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.1036
    Cell Significance Index: -3.6400
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.1047
    Cell Significance Index: -2.2200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.1062
    Cell Significance Index: -2.1000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.1071
    Cell Significance Index: -2.1500
  • Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
    Fold Change: -0.1081
    Cell Significance Index: -1.1800
  • Cell Name: helper T cell (CL0000912)
    Fold Change: -0.1119
    Cell Significance Index: -1.5900
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.1159
    Cell Significance Index: -1.9500

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** INKA2 AS1 is a long non-coding RNA (lncRNA) that is antisense to the INKA2 gene, a protein-coding gene involved in various cellular processes. The INKA2 AS1 transcript is characterized by its long length (approximately 15 kb) and its ability to regulate gene expression through various mechanisms, including transcriptional and post-transcriptional control. INKA2 AS1 is significantly expressed in various cell types, including stem cells, which suggests its potential role in maintaining tissue homeostasis and promoting cellular renewal. **Pathways and Functions:** INKA2 AS1 has been implicated in several biological pathways, including: 1. **Cell proliferation and differentiation:** INKA2 AS1 has been shown to regulate the expression of genes involved in cell cycle progression and differentiation, suggesting its role in maintaining tissue homeostasis. 2. **Stem cell maintenance:** INKA2 AS1 has been found to be highly expressed in stem cells, including intestinal crypt stem cells and cerebral cortex GABAergic interneurons, suggesting its role in maintaining these cell populations. 3. **Innate immune responses:** INKA2 AS1 has been implicated in the regulation of innate immune responses, including the expression of genes involved in the recognition of pathogens and the activation of immune cells. 4. **Neurodevelopment:** INKA2 AS1 has been found to be involved in neurodevelopmental processes, including the regulation of gene expression in the cerebral cortex and the maintenance of GABAergic interneurons. **Clinical Significance:** Dysregulation of INKA2 AS1 has been implicated in various diseases, including: 1. **Cancer:** Alterations in INKA2 AS1 expression have been found in various types of cancer, including colon cancer and leukemia, suggesting its potential role as a tumor suppressor. 2. **Neurological disorders:** INKA2 AS1 has been implicated in the pathogenesis of neurological disorders, including Alzheimer's disease and Parkinson's disease, suggesting its potential role in neurodegeneration. 3. **Immune-mediated diseases:** INKA2 AS1 has been found to be involved in the regulation of innate immune responses, suggesting its potential role in the pathogenesis of immune-mediated diseases, such as autoimmune arthritis. In conclusion, INKA2 AS1 is a non-coding RNA that plays a crucial role in multiple biological processes, including cell proliferation, differentiation, and survival. Its dysregulation has been implicated in various diseases, highlighting its potential as a therapeutic target. Further research is needed to fully elucidate the functions and clinical significance of INKA2 AS1.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.