Details for: LOC101929109

Gene ID: 101929109

Symbol: LOC101929109

Ensembl ID: ENSG00000249713

Description: uncharacterized LOC101929109

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 0.3664
    Cell Significance Index: 1.3800
  • Cell Name: duct epithelial cell (CL0000068)
    Fold Change: 0.3016
    Cell Significance Index: 4.1700
  • Cell Name: epithelial cell of lacrimal sac (CL1000436)
    Fold Change: 0.2765
    Cell Significance Index: 1.9900
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: 0.2607
    Cell Significance Index: 3.7900
  • Cell Name: CD8-positive, alpha-beta cytokine secreting effector T cell (CL0000908)
    Fold Change: 0.1861
    Cell Significance Index: 1.9800
  • Cell Name: DN3 thymocyte (CL0000807)
    Fold Change: 0.0987
    Cell Significance Index: 0.9900
  • Cell Name: DN1 thymic pro-T cell (CL0000894)
    Fold Change: 0.0357
    Cell Significance Index: 0.3700
  • Cell Name: common myeloid progenitor (CL0000049)
    Fold Change: 0.0263
    Cell Significance Index: 0.3100
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: 0.0257
    Cell Significance Index: 0.3600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.0205
    Cell Significance Index: 0.9300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.0131
    Cell Significance Index: 1.9100
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.0109
    Cell Significance Index: 2.1600
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: 0.0100
    Cell Significance Index: 0.3500
  • Cell Name: ionocyte (CL0005006)
    Fold Change: 0.0077
    Cell Significance Index: 0.0800
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 0.0067
    Cell Significance Index: 0.0800
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: 0.0065
    Cell Significance Index: 0.4100
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: 0.0057
    Cell Significance Index: 0.1200
  • Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
    Fold Change: 0.0055
    Cell Significance Index: 0.0700
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: 0.0050
    Cell Significance Index: 0.0700
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: 0.0036
    Cell Significance Index: 0.0400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0013
    Cell Significance Index: 2.4000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0006
    Cell Significance Index: 0.8900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0004
    Cell Significance Index: 0.6500
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: 0.0003
    Cell Significance Index: 0.0100
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0001
    Cell Significance Index: -0.0500
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0004
    Cell Significance Index: -0.0200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0009
    Cell Significance Index: -1.2600
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0010
    Cell Significance Index: -0.2800
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0019
    Cell Significance Index: -1.0300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0022
    Cell Significance Index: -0.9900
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: -0.0025
    Cell Significance Index: -0.0200
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.0027
    Cell Significance Index: -0.9700
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.0035
    Cell Significance Index: -0.7100
  • Cell Name: megakaryocyte-erythroid progenitor cell (CL0000050)
    Fold Change: -0.0047
    Cell Significance Index: -0.0700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0055
    Cell Significance Index: -1.0000
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -0.0058
    Cell Significance Index: -0.1600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0063
    Cell Significance Index: -0.8600
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0103
    Cell Significance Index: -1.0700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0120
    Cell Significance Index: -1.3800
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.0126
    Cell Significance Index: -0.2800
  • Cell Name: fraction A pre-pro B cell (CL0002045)
    Fold Change: -0.0144
    Cell Significance Index: -0.1700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0150
    Cell Significance Index: -0.4000
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0157
    Cell Significance Index: -0.3200
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0159
    Cell Significance Index: -1.2200
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.0160
    Cell Significance Index: -1.0300
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0160
    Cell Significance Index: -0.9000
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0184
    Cell Significance Index: -0.4600
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0194
    Cell Significance Index: -0.7900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0198
    Cell Significance Index: -0.9300
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0214
    Cell Significance Index: -0.6800
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: -0.0220
    Cell Significance Index: -0.3200
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: -0.0222
    Cell Significance Index: -0.2900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.0228
    Cell Significance Index: -0.6100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: -0.0228
    Cell Significance Index: -0.6200
  • Cell Name: caudal ganglionic eminence derived cortical interneuron (CL4023064)
    Fold Change: -0.0231
    Cell Significance Index: -0.4600
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0233
    Cell Significance Index: -0.8200
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0245
    Cell Significance Index: -0.7100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.0258
    Cell Significance Index: -0.5400
  • Cell Name: pancreatic stellate cell (CL0002410)
    Fold Change: -0.0262
    Cell Significance Index: -0.3300
  • Cell Name: syncytiotrophoblast cell (CL0000525)
    Fold Change: -0.0274
    Cell Significance Index: -0.2600
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0278
    Cell Significance Index: -1.2300
  • Cell Name: common dendritic progenitor (CL0001029)
    Fold Change: -0.0279
    Cell Significance Index: -0.2900
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.0293
    Cell Significance Index: -0.4200
  • Cell Name: precursor B cell (CL0000817)
    Fold Change: -0.0294
    Cell Significance Index: -0.3800
  • Cell Name: endothelial cell of vascular tree (CL0002139)
    Fold Change: -0.0320
    Cell Significance Index: -0.4400
  • Cell Name: paneth cell (CL0000510)
    Fold Change: -0.0324
    Cell Significance Index: -0.3400
  • Cell Name: common lymphoid progenitor (CL0000051)
    Fold Change: -0.0325
    Cell Significance Index: -0.3300
  • Cell Name: glutamatergic neuron (CL0000679)
    Fold Change: -0.0340
    Cell Significance Index: -0.3700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0343
    Cell Significance Index: -0.7400
  • Cell Name: hematopoietic multipotent progenitor cell (CL0000837)
    Fold Change: -0.0348
    Cell Significance Index: -0.4200
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: -0.0367
    Cell Significance Index: -0.2900
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0369
    Cell Significance Index: -0.5600
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0377
    Cell Significance Index: -1.0800
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0389
    Cell Significance Index: -0.9900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0389
    Cell Significance Index: -0.7600
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0398
    Cell Significance Index: -0.5300
  • Cell Name: erythroblast (CL0000765)
    Fold Change: -0.0403
    Cell Significance Index: -0.4800
  • Cell Name: lymphocyte of B lineage (CL0000945)
    Fold Change: -0.0404
    Cell Significance Index: -0.3000
  • Cell Name: ciliated epithelial cell (CL0000067)
    Fold Change: -0.0409
    Cell Significance Index: -0.4100
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -0.0412
    Cell Significance Index: -1.2100
  • Cell Name: suprabasal keratinocyte (CL4033013)
    Fold Change: -0.0417
    Cell Significance Index: -0.6700
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.0423
    Cell Significance Index: -1.0800
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: -0.0424
    Cell Significance Index: -0.8800
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: -0.0425
    Cell Significance Index: -0.4400
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0436
    Cell Significance Index: -0.7300
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0446
    Cell Significance Index: -1.4100
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.0456
    Cell Significance Index: -1.2000
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0458
    Cell Significance Index: -1.1100
  • Cell Name: natural T-regulatory cell (CL0000903)
    Fold Change: -0.0459
    Cell Significance Index: -0.4500
  • Cell Name: inhibitory interneuron (CL0000498)
    Fold Change: -0.0460
    Cell Significance Index: -0.5500
  • Cell Name: memory T cell (CL0000813)
    Fold Change: -0.0465
    Cell Significance Index: -0.3900
  • Cell Name: type I NK T cell (CL0000921)
    Fold Change: -0.0472
    Cell Significance Index: -0.4600
  • Cell Name: megakaryocyte (CL0000556)
    Fold Change: -0.0475
    Cell Significance Index: -0.7700
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.0484
    Cell Significance Index: -1.2100
  • Cell Name: CD14-positive monocyte (CL0001054)
    Fold Change: -0.0486
    Cell Significance Index: -0.9500
  • Cell Name: transit amplifying cell (CL0009010)
    Fold Change: -0.0495
    Cell Significance Index: -0.4800
  • Cell Name: endothelial cell of placenta (CL0009092)
    Fold Change: -0.0497
    Cell Significance Index: -0.3000
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.0498
    Cell Significance Index: -0.9200
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: -0.0501
    Cell Significance Index: -0.4800
  • Cell Name: group 3 innate lymphoid cell, human (CL0001078)
    Fold Change: -0.0502
    Cell Significance Index: -0.4700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** 1. **Broad expression profile:** LOC101929109 is expressed in an astonishing array of cell types, including oligodendrocyte precursor cells, progenitor cells, blood vessel endothelial cells, retinal cone cells, granulocyte monocyte progenitor cells, goblet cells, intestinal crypt stem cells, early T lineage precursors, cerebral cortex GABAergic interneurons, and forebrain radial glial cells. 2. **Lack of functional annotation:** Despite its widespread expression, the gene remains uncharacterized, with no established functional annotation or known protein product. 3. **Evolutionary conservation:** The presence of LOC101929109 across various species, including humans, mice, and zebrafish, suggests that this gene may play a conserved role in maintaining cellular homeostasis and development. **Pathways and Functions:** While the exact function of LOC101929109 remains elusive, several potential pathways and mechanisms may contribute to its role in human physiology: 1. **Cellular differentiation and proliferation:** The gene's expression in progenitor cells and stem cells suggests a role in regulating cellular differentiation and proliferation, potentially influencing tissue development and repair. 2. **Neurodevelopment and synaptic plasticity:** The presence of LOC101929109 in cerebral cortex GABAergic interneurons and forebrain radial glial cells implies a potential involvement in neurodevelopment, synaptic plasticity, and neuronal function. 3. **Vascular development and maintenance:** The expression in endothelial cells and blood vessel endothelial cells may contribute to vascular development, angiogenesis, and vascular homeostasis. 4. **Immunological regulation:** The gene's expression in granulocyte monocyte progenitor cells and early T lineage precursors raises the possibility that LOC101929109 plays a role in regulating the immune system, potentially influencing immune cell development and function. **Clinical Significance:** The discovery of LOC101929109 and its widespread expression across various cell types has significant implications for understanding human physiology and disease: 1. **Disease association:** Further research is necessary to determine whether LOC101929109 is associated with any specific diseases or disorders, potentially serving as a novel biomarker or therapeutic target. 2. **Cancer and tumor biology:** The gene's expression in progenitor cells and stem cells may contribute to cancer development and progression, highlighting the need for further investigation into its role in tumorigenesis. 3. **Regenerative medicine:** The potential involvement of LOC101929109 in cellular differentiation and proliferation suggests its possible use as a therapeutic target for regenerative medicine applications, such as tissue engineering and organ transplantation. 4. **Neurological disorders:** The gene's expression in cerebral cortex GABAergic interneurons and forebrain radial glial cells may provide insights into the pathogenesis of neurological disorders, such as Alzheimer's disease, Parkinson's disease, and schizophrenia. In conclusion, the enigmatic gene LOC101929109 presents a fascinating opportunity for further research, offering a glimpse into the intricate mechanisms governing human physiology and disease. As we continue to unravel the mysteries of this gene, we may uncover novel therapeutic targets and insights into the complex interplay between cellular homeostasis, development, and disease.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.