Details for: GALNT2
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 310.8421
Cell Significance Index: -48.3500 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 184.4322
Cell Significance Index: -46.7800 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 112.1213
Cell Significance Index: -52.9400 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 107.8873
Cell Significance Index: -43.8300 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 98.0782
Cell Significance Index: -50.4500 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 45.9338
Cell Significance Index: -43.8600 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 40.7476
Cell Significance Index: -50.2400 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 18.8196
Cell Significance Index: -50.4200 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 14.1393
Cell Significance Index: -30.9500 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 12.9142
Cell Significance Index: -50.9600 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 4.7594
Cell Significance Index: 127.5300 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 2.7133
Cell Significance Index: 37.0200 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 2.5977
Cell Significance Index: 515.5300 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 2.2268
Cell Significance Index: 798.7100 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 1.9693
Cell Significance Index: 395.0300 - Cell Name: centrilobular region hepatocyte (CL0019029)
Fold Change: 1.8825
Cell Significance Index: 31.7100 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 1.2375
Cell Significance Index: 211.3100 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: 1.1897
Cell Significance Index: 30.5800 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 1.1660
Cell Significance Index: 75.2300 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 1.0914
Cell Significance Index: 754.8800 - Cell Name: type I muscle cell (CL0002211)
Fold Change: 0.8795
Cell Significance Index: 21.4600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: 0.7944
Cell Significance Index: 44.5800 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: 0.7049
Cell Significance Index: 17.6200 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.6940
Cell Significance Index: 626.6000 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: 0.6187
Cell Significance Index: 38.0300 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.5655
Cell Significance Index: 101.9500 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.5506
Cell Significance Index: 42.2600 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: 0.5043
Cell Significance Index: 62.0100 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: 0.4533
Cell Significance Index: 697.7700 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.4453
Cell Significance Index: 30.8000 - Cell Name: retinal rod cell (CL0000604)
Fold Change: 0.3238
Cell Significance Index: 3.8600 - Cell Name: cell in vitro (CL0001034)
Fold Change: 0.3024
Cell Significance Index: 165.1600 - Cell Name: anterior lens cell (CL0002223)
Fold Change: 0.2898
Cell Significance Index: 534.4900 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: 0.2684
Cell Significance Index: 11.8700 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.2485
Cell Significance Index: 7.1600 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.2201
Cell Significance Index: 30.2200 - Cell Name: cortical interneuron (CL0008031)
Fold Change: 0.1960
Cell Significance Index: 4.7000 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: 0.1807
Cell Significance Index: 11.3900 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: 0.1755
Cell Significance Index: 330.3600 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: 0.1387
Cell Significance Index: 188.5300 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 0.1286
Cell Significance Index: 6.6800 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.1209
Cell Significance Index: 11.9600 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: 0.1181
Cell Significance Index: 75.0000 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 0.0920
Cell Significance Index: 4.1700 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0721
Cell Significance Index: 31.8800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: 0.0636
Cell Significance Index: 2.4100 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.0539
Cell Significance Index: 2.8100 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: 0.0475
Cell Significance Index: 21.5800 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 0.0426
Cell Significance Index: 1.1900 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: 0.0393
Cell Significance Index: 1.3800 - Cell Name: Purkinje cell (CL0000121)
Fold Change: 0.0365
Cell Significance Index: 0.8000 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0186
Cell Significance Index: 1.2500 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.0049
Cell Significance Index: -0.3600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.0075
Cell Significance Index: -0.3500 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0211
Cell Significance Index: -15.6600 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.0250
Cell Significance Index: -3.6300 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0261
Cell Significance Index: -16.3100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0350
Cell Significance Index: -26.4800 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: -0.0403
Cell Significance Index: -7.6700 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: -0.0480
Cell Significance Index: -1.0300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0536
Cell Significance Index: -39.2900 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.0543
Cell Significance Index: -1.0600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0684
Cell Significance Index: -38.5700 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0774
Cell Significance Index: -2.2100 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.1142
Cell Significance Index: -11.6700 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1259
Cell Significance Index: -16.1400 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1311
Cell Significance Index: -3.3500 - Cell Name: periportal region hepatocyte (CL0019026)
Fold Change: -0.1369
Cell Significance Index: -2.0200 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1507
Cell Significance Index: -17.5600 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.1534
Cell Significance Index: -32.3200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.1555
Cell Significance Index: -44.7300 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: -0.1664
Cell Significance Index: -2.3900 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1940
Cell Significance Index: -25.0600 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: -0.2352
Cell Significance Index: -27.7400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.2462
Cell Significance Index: -28.2100 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.2595
Cell Significance Index: -12.2000 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.3110
Cell Significance Index: -5.3300 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.3334
Cell Significance Index: -7.1000 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.3391
Cell Significance Index: -38.7100 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.3930
Cell Significance Index: -40.9200 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.4282
Cell Significance Index: -6.8700 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.4317
Cell Significance Index: -8.9600 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.4982
Cell Significance Index: -7.1400 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.5965
Cell Significance Index: -47.2400 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.6262
Cell Significance Index: -44.2900 - Cell Name: umbrella cell of urothelium (CL4030056)
Fold Change: -0.6293
Cell Significance Index: -5.8000 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.6411
Cell Significance Index: -13.8900 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.6772
Cell Significance Index: -21.6900 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: -0.6888
Cell Significance Index: -13.6200 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.7156
Cell Significance Index: -43.8700 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.7343
Cell Significance Index: -15.5900 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: -0.8194
Cell Significance Index: -21.8800 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.8407
Cell Significance Index: -44.1400 - Cell Name: peg cell (CL4033014)
Fold Change: -0.8582
Cell Significance Index: -19.8300 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.8958
Cell Significance Index: -23.9600 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.8982
Cell Significance Index: -15.0300 - Cell Name: VIP GABAergic cortical interneuron (CL4023016)
Fold Change: -0.9045
Cell Significance Index: -18.1600 - Cell Name: astrocyte of the cerebral cortex (CL0002605)
Fold Change: -0.9199
Cell Significance Index: -15.9100 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.9239
Cell Significance Index: -24.3000 - Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
Fold Change: -0.9544
Cell Significance Index: -20.6200
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1313190343
Symbol: GALT2_HUMAN
Name: Polypeptide N-acetylgalactosaminyltransferase 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7592619
Title: Purification and cDNA cloning of a human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase.
PubMed ID: 7592619
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16710414
Title: The DNA sequence and biological annotation of human chromosome 1.
PubMed ID: 16710414
DOI: 10.1038/nature04727
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9295285
Title: Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3.
PubMed ID: 9295285
PubMed ID: 9394011
Title: Localization of three human polypeptide GalNAc-transferases in HeLa cells suggests initiation of O-linked glycosylation throughout the Golgi apparatus.
PubMed ID: 9394011
DOI: 10.1242/jcs.111.1.45
PubMed ID: 12438318
Title: Initiation of O-glycan synthesis in IgA1 hinge region is determined by a single enzyme, UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2.
PubMed ID: 12438318
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 37453717
Title: Mapping the Human Chondroitin Sulfate Glycoproteome Reveals an Unexpected Correlation Between Glycan Sulfation and Attachment Site Characteristics.
PubMed ID: 37453717
PubMed ID: 16434399
Title: Dynamic association between the catalytic and lectin domains of human UDP-GalNAc:polypeptide alpha-N-acetylgalactosaminyltransferase-2.
PubMed ID: 16434399
PubMed ID: 24954443
Title: Substrate-guided front-face reaction revealed by combined structural snapshots and metadynamics for the polypeptide N-acetylgalactosaminyltransferase2.
PubMed ID: 24954443
PubMed ID: 25939779
Title: Dynamic interplay between catalytic and lectin domains of GalNAc-transferases modulates protein O-glycosylation.
PubMed ID: 25939779
DOI: 10.1038/ncomms7937
PubMed ID: 27508872
Title: Loss of function of GALNT2 lowers high-density lipoproteins in humans, nonhuman primates, and rodents.
PubMed ID: 27508872
PubMed ID: 32293671
Title: Novel congenital disorder of O-linked glycosylation caused by GALNT2 loss of function.
PubMed ID: 32293671
Sequence Information:
- Length: 571
- Mass: 64733
- Checksum: D9A0F5D17C55BAF2
- Sequence:
MRRRSRMLLC FAFLWVLGIA YYMYSGGGSA LAGGAGGGAG RKEDWNEIDP IKKKDLHHSN GEEKAQSMET LPPGKVRWPD FNQEAYVGGT MVRSGQDPYA RNKFNQVESD KLRMDRAIPD TRHDQCQRKQ WRVDLPATSV VITFHNEARS ALLRTVVSVL KKSPPHLIKE IILVDDYSND PEDGALLGKI EKVRVLRNDR REGLMRSRVR GADAAQAKVL TFLDSHCECN EHWLEPLLER VAEDRTRVVS PIIDVINMDN FQYVGASADL KGGFDWNLVF KWDYMTPEQR RSRQGNPVAP IKTPMIAGGL FVMDKFYFEE LGKYDMMMDV WGGENLEISF RVWQCGGSLE IIPCSRVGHV FRKQHPYTFP GGSGTVFARN TRRAAEVWMD EYKNFYYAAV PSARNVPYGN IQSRLELRKK LSCKPFKWYL ENVYPELRVP DHQDIAFGAL QQGTNCLDTL GHFADGVVGV YECHNAGGNQ EWALTKEKSV KHMDLCLTVV DRAPGSLIKL QGCRENDSRQ KWEQIEGNSK LRHVGSNLCL DSRTAKSGGL SVEVCGPALS QQWKFTLNLQ Q
Genular Protein ID: 336674727
Symbol: B7Z6K2_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Sequence Information:
- Length: 533
- Mass: 60826
- Checksum: C8166676727BF4BF
- Sequence:
MADREDWNEI DPIKKKDLHH SNGEEKAQSM ETLPPGKVRW PDFNQEAYVG GTMVRSGQDP YARNKFNQVE SDKLRMDRAI PDTRHDQCQR KQWRVDLPAT SVVITFHNEA RSALLRTVVS VLKKSPPHLI KEIILVDDYS NDPEDGALLG KIEKVRVLRN DRREGLMRSR VRGADAAQAK VLTFLDSHCE CNEHWLEPLL ERVAEDRTRV VSPIIDVINM DNFQYVGASA DLKGGFDWNL VFKWDYMTPE QRRSRQGNPV APIKTPMIAG GLFVMDKFYF EELGKYDMMM DVWGGENLEI SFRVWQCGGS LEIIPCSRVG HVFRKQHPYT FPGGSGTVFA RNTRRAAEVW MDEYKNFYYA AVPSARNVPY GNIQSRLELR KKLSCKPFKW YLENVYPELR VPDHQDIAFG ALQQGTNCLD TLGHFADGVV GVYECHNAGG NQEWALTKEK SVKHMDLCLT VVDRAPGSLI KLQGCRENDS RQKWEQIEGN SKLRHVGSNL CLDSRTAKSG GLSVEMCGPA LSQQWKFTLN LQQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.